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The map label for this gene is appB [H]

Identifier: 13471629

GI number: 13471629

Start: 1377413

End: 1378447

Strand: Reverse

Name: appB [H]

Synonym: mll1659

Alternate gene names: 13471629

Gene position: 1378447-1377413 (Counterclockwise)

Preceding gene: 13471630

Following gene: 13471628

Centisome position: 19.59

GC content: 60.19

Gene sequence:

>1035_bases
ATGCTTTCCTTCGTTATCAGGCGTCTTGGCACCATGGCACTGACGATGCTGTGCCTGACTATGATCGTCTTTTTCCTGAT
CAACCTTGAACCCAATCTGAAGAAGCTGGCGATCAGCCAGACCGAAATGCACACGTCGGCCGAGCAGCTCGAGAGCTGGC
TGGTCAATCATGGCTACCGGCAGAACTTCTTTGTCCGCTACGGGCAGTGGCTGGGCGTCATGCCAAAGCAGCCGGTGACC
GACCCGGCGACCGGCAAGCCGGCGCAGCGTTTCTCGTTCTGCAATGACCCGGTCGTGCCGACCTTCGCCGGCGTCGTCGA
AGGCGATTTCGGCTGCTCGACCAAGTTCAAGACAACGGTCGCCTCGAAATTGTTTCCCGCACTTGGCGCCACTGGCATCC
TGATGTTCTGTGTGTTGGCGGTGATGGTGCCGGTATCGCTCTTGATCGGCATCCTGGCCGGCATGCGCGAGGGGTCGCGA
ACCGACCGGGTGCTTTCGGTCGCCTCGATCGCCTCGACGGCGACGCCCGAATATGTGTCGGGCGTCATCTTCACCGTCAT
CTTCGCCTCATGGCTCGGCTGGCTGAACGGTTCGGCCGCGTCGGCAAGCCAGGGCATCACCTTCTACAATTTCACCCTGC
CGGTGATGACGTTGGCGATCTACGGCATCGGCTACATCGCCCGCATGACACGCGCCTCGATGGTCGAGGTGATGACGCAG
CAATATATCCGCACCGCCCGGCTGAAGGGCCTCTCCTTCGGCGGCGTGGTGGTGAAACATGCGCTGCGCAACGCGCTGAT
CGCACCGTTCACCGTCATCATGCTGCAATTTCCCTGGCTGCTCACCGGCGTCGTCATCGTCGAGGTGATGTTCCGCTACC
AGGGCTTCGGCTACACGCTGGTCGAGGCCGCCGGCAACAACGACATCGACCTTTTGCTTGGCTGCTCGCTGGTCTCGGTG
TTCATCGTCTTGATCACACAGCTCATTTCCGATGTCGGCTACGCGTTTCTCAATCCGCGTATCAGAGTTCAGTAG

Upstream 100 bases:

>100_bases
TGATTGCATCCGAGGGCCTGTTTGACAGCCAGTTCCGCCGTCGCGGCTGAGGTGACTTTTCAACGGGCTCCAACCCCAAC
CAGACCGGCAGGGGGCCGCC

Downstream 100 bases:

>100_bases
GGGGCGAAGCGGATGCAGGTCCAATATATCAGTGCCTTCACCGTCATTCTCGAAGTGCTGTCGCGCTTCTGGCCGGTCTG
GATCGCGCTCATCATCGTCA

Product: permease protein of oligopeptide ABC transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MLSFVIRRLGTMALTMLCLTMIVFFLINLEPNLKKLAISQTEMHTSAEQLESWLVNHGYRQNFFVRYGQWLGVMPKQPVT
DPATGKPAQRFSFCNDPVVPTFAGVVEGDFGCSTKFKTTVASKLFPALGATGILMFCVLAVMVPVSLLIGILAGMREGSR
TDRVLSVASIASTATPEYVSGVIFTVIFASWLGWLNGSAASASQGITFYNFTLPVMTLAIYGIGYIARMTRASMVEVMTQ
QYIRTARLKGLSFGGVVVKHALRNALIAPFTVIMLQFPWLLTGVVIVEVMFRYQGFGYTLVEAAGNNDIDLLLGCSLVSV
FIVLITQLISDVGYAFLNPRIRVQ

Sequences:

>Translated_344_residues
MLSFVIRRLGTMALTMLCLTMIVFFLINLEPNLKKLAISQTEMHTSAEQLESWLVNHGYRQNFFVRYGQWLGVMPKQPVT
DPATGKPAQRFSFCNDPVVPTFAGVVEGDFGCSTKFKTTVASKLFPALGATGILMFCVLAVMVPVSLLIGILAGMREGSR
TDRVLSVASIASTATPEYVSGVIFTVIFASWLGWLNGSAASASQGITFYNFTLPVMTLAIYGIGYIARMTRASMVEVMTQ
QYIRTARLKGLSFGGVVVKHALRNALIAPFTVIMLQFPWLLTGVVIVEVMFRYQGFGYTLVEAAGNNDIDLLLGCSLVSV
FIVLITQLISDVGYAFLNPRIRVQ
>Mature_344_residues
MLSFVIRRLGTMALTMLCLTMIVFFLINLEPNLKKLAISQTEMHTSAEQLESWLVNHGYRQNFFVRYGQWLGVMPKQPVT
DPATGKPAQRFSFCNDPVVPTFAGVVEGDFGCSTKFKTTVASKLFPALGATGILMFCVLAVMVPVSLLIGILAGMREGSR
TDRVLSVASIASTATPEYVSGVIFTVIFASWLGWLNGSAASASQGITFYNFTLPVMTLAIYGIGYIARMTRASMVEVMTQ
QYIRTARLKGLSFGGVVVKHALRNALIAPFTVIMLQFPWLLTGVVIVEVMFRYQGFGYTLVEAAGNNDIDLLLGCSLVSV
FIVLITQLISDVGYAFLNPRIRVQ

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=344, Percent_Identity=29.3604651162791, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1789965, Length=370, Percent_Identity=27.5675675675676, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1787497, Length=346, Percent_Identity=27.7456647398844, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1789888, Length=345, Percent_Identity=25.7971014492754, Blast_Score=101, Evalue=9e-23,
Organism=Escherichia coli, GI1788504, Length=253, Percent_Identity=28.8537549407115, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787761, Length=259, Percent_Identity=29.3436293436293, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787550, Length=283, Percent_Identity=27.9151943462898, Blast_Score=83, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 37707; Mature: 37707

Theoretical pI: Translated: 9.52; Mature: 9.52

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSFVIRRLGTMALTMLCLTMIVFFLINLEPNLKKLAISQTEMHTSAEQLESWLVNHGYR
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
QNFFVRYGQWLGVMPKQPVTDPATGKPAQRFSFCNDPVVPTFAGVVEGDFGCSTKFKTTV
HHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCCCCCHHHHHHHCCCCCCCCHHHHHH
ASKLFPALGATGILMFCVLAVMVPVSLLIGILAGMREGSRTDRVLSVASIASTATPEYVS
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHH
GVIFTVIFASWLGWLNGSAASASQGITFYNFTLPVMTLAIYGIGYIARMTRASMVEVMTQ
HHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QYIRTARLKGLSFGGVVVKHALRNALIAPFTVIMLQFPWLLTGVVIVEVMFRYQGFGYTL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
VEAAGNNDIDLLLGCSLVSVFIVLITQLISDVGYAFLNPRIRVQ
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECC
>Mature Secondary Structure
MLSFVIRRLGTMALTMLCLTMIVFFLINLEPNLKKLAISQTEMHTSAEQLESWLVNHGYR
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
QNFFVRYGQWLGVMPKQPVTDPATGKPAQRFSFCNDPVVPTFAGVVEGDFGCSTKFKTTV
HHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCCCCCHHHHHHHCCCCCCCCHHHHHH
ASKLFPALGATGILMFCVLAVMVPVSLLIGILAGMREGSRTDRVLSVASIASTATPEYVS
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHH
GVIFTVIFASWLGWLNGSAASASQGITFYNFTLPVMTLAIYGIGYIARMTRASMVEVMTQ
HHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QYIRTARLKGLSFGGVVVKHALRNALIAPFTVIMLQFPWLLTGVVIVEVMFRYQGFGYTL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
VEAAGNNDIDLLLGCSLVSVFIVLITQLISDVGYAFLNPRIRVQ
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]