BacMap

Definition	Mesorhizobium loti MAFF303099 chromosome, complete genome.
Accession	NC_002678
Length	7,036,071

Click here to switch to the map view.

The map label for this gene is fabG [C]

Identifier: 13471572

GI number: 13471572

Start: 1321425

End: 1322156

Strand: Direct

Name: fabG [C]

Synonym: mlr1583

Alternate gene names: 13471572

Gene position: 1321425-1322156 (Clockwise)

Preceding gene: 13471570

Following gene: 13471574

Centisome position: 18.78

GC content: 65.44

Gene sequence:

>732_bases
ATGTCCCAGTCTCTGCACGGCAAAACCGCAATCGTCACCGGCAGTTCGCGCGGCATCGGCCGGGCGATCGCCGAAGGGCT
CGCGGCTGAGGGCGCTGCCGTCGTCGTCAATTATGTCGGCAACCAGAAAGCCGCGGATGAGGTCGTCGCCGGCATCGCCG
GCAAGGGAGGAAAGGCAATCGCCATCCAGGCCGACATATCAAGCGTTTCGGATGTCCGCCGCTTGTTTGACGAGACCGAG
AGCAGGCTGGGCGCGATCGACATCGTCGTCGCCAATGTTGGCGTCGCCGTCATCAAACCGCTGACCGAAGCAACCGAAGC
CGATTTCGACCTTGTCTTCGGCACCAATGCCAAGGGCACCTTCTTCACGCTGCAGGAAGCAGCGCGCCGGGTAAGGGATG
GCGGCCGTATCATCGCCGTCTCCACCGGCGGCACAAAGATGTTCTTCACCCAGACGGCGCTCTACCTCGGCAGCAAGGGC
GCAGTCGAACAGTTCGTCCGCGTGCTCTCGCGTGAACTCGGATCGCGCGGCATCACCGTCAATGCGCTGTCGCCGGGCTT
CACTGACACAGACCTGCTCCCCGAGCGCGATCGCGCCGTGGCGGCCGGCATGTCGCCCTTCGGCAGGATCGGCGCGCCGC
ACGACGTTGCCGATGTCGCGGTCTTCCTGGCCAGCGACGAGGCCCGCTGGCTGACCGGCGACAACATCCAGGCCGGCGGT
GGCGTGGCGTAA

Upstream 100 bases:

>100_bases
ATAATAGGGCATTATCTGATCAATTGCATGCCGCTATTTCTCAGCCATCGGCCACATCGCACCCAAAGCTGCGGGCCAGA
ATGGTTGAAGGAAATTGATC

Downstream 100 bases:

>100_bases
GGATAGGCAGTAGGCAGTAGGCAGTAGGCAGCAGGCAGCAGGCAGCAGGCAGCAGGAAAATAGCAAAGGTGACATTCAAA
GCGGCAGTATAATAAACGAT

Product: dehydrogenase/reductase

Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]

Alternate protein names: ORFC [H]

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MSQSLHGKTAIVTGSSRGIGRAIAEGLAAEGAAVVVNYVGNQKAADEVVAGIAGKGGKAIAIQADISSVSDVRRLFDETE
SRLGAIDIVVANVGVAVIKPLTEATEADFDLVFGTNAKGTFFTLQEAARRVRDGGRIIAVSTGGTKMFFTQTALYLGSKG
AVEQFVRVLSRELGSRGITVNALSPGFTDTDLLPERDRAVAAGMSPFGRIGAPHDVADVAVFLASDEARWLTGDNIQAGG
GVA

Sequences:

>Translated_243_residues
MSQSLHGKTAIVTGSSRGIGRAIAEGLAAEGAAVVVNYVGNQKAADEVVAGIAGKGGKAIAIQADISSVSDVRRLFDETE
SRLGAIDIVVANVGVAVIKPLTEATEADFDLVFGTNAKGTFFTLQEAARRVRDGGRIIAVSTGGTKMFFTQTALYLGSKG
AVEQFVRVLSRELGSRGITVNALSPGFTDTDLLPERDRAVAAGMSPFGRIGAPHDVADVAVFLASDEARWLTGDNIQAGG
GVA
>Mature_242_residues
SQSLHGKTAIVTGSSRGIGRAIAEGLAAEGAAVVVNYVGNQKAADEVVAGIAGKGGKAIAIQADISSVSDVRRLFDETES
RLGAIDIVVANVGVAVIKPLTEATEADFDLVFGTNAKGTFFTLQEAARRVRDGGRIIAVSTGGTKMFFTQTALYLGSKGA
VEQFVRVLSRELGSRGITVNALSPGFTDTDLLPERDRAVAAGMSPFGRIGAPHDVADVAVFLASDEARWLTGDNIQAGGG
VA

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=256, Percent_Identity=33.984375, Blast_Score=115, Evalue=3e-26,
Organism=Homo sapiens, GI40254992, Length=241, Percent_Identity=31.9502074688797, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI32483357, Length=249, Percent_Identity=30.5220883534137, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI19923817, Length=250, Percent_Identity=28.4, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI7705925, Length=253, Percent_Identity=28.8537549407115, Blast_Score=85, Evalue=5e-17,
Organism=Homo sapiens, GI5031737, Length=246, Percent_Identity=29.2682926829268, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI209862901, Length=207, Percent_Identity=29.951690821256, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI19923983, Length=207, Percent_Identity=29.951690821256, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI59889578, Length=194, Percent_Identity=32.4742268041237, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI126723750, Length=249, Percent_Identity=28.9156626506024, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI31542939, Length=201, Percent_Identity=30.3482587064677, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI109715829, Length=241, Percent_Identity=28.2157676348548, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI4758504, Length=260, Percent_Identity=28.4615384615385, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI33667109, Length=193, Percent_Identity=30.0518134715026, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI10190746, Length=217, Percent_Identity=26.2672811059908, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1787335, Length=246, Percent_Identity=33.3333333333333, Blast_Score=124, Evalue=4e-30,
Organism=Escherichia coli, GI2367175, Length=244, Percent_Identity=36.4754098360656, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI2367365, Length=231, Percent_Identity=35.4978354978355, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1787905, Length=244, Percent_Identity=35.2459016393443, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1790717, Length=246, Percent_Identity=28.4552845528455, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1789208, Length=247, Percent_Identity=31.5789473684211, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI87082100, Length=254, Percent_Identity=31.8897637795276, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1788459, Length=245, Percent_Identity=26.530612244898, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1789378, Length=237, Percent_Identity=31.2236286919831, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI87082160, Length=247, Percent_Identity=29.1497975708502, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1789057, Length=254, Percent_Identity=28.3464566929134, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786812, Length=253, Percent_Identity=28.4584980237154, Blast_Score=72, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17555706, Length=259, Percent_Identity=30.8880308880309, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17561402, Length=254, Percent_Identity=31.1023622047244, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17560676, Length=249, Percent_Identity=30.1204819277108, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI25147288, Length=249, Percent_Identity=32.1285140562249, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI115534694, Length=243, Percent_Identity=28.8065843621399, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI193204405, Length=262, Percent_Identity=31.6793893129771, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17562910, Length=258, Percent_Identity=30.6201550387597, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI71994604, Length=251, Percent_Identity=28.2868525896414, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17560220, Length=261, Percent_Identity=31.4176245210728, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17538182, Length=258, Percent_Identity=28.6821705426357, Blast_Score=80, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17531453, Length=257, Percent_Identity=30.7392996108949, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17560150, Length=257, Percent_Identity=29.9610894941634, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17563726, Length=258, Percent_Identity=27.5193798449612, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17568967, Length=196, Percent_Identity=33.6734693877551, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17538480, Length=272, Percent_Identity=30.8823529411765, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562906, Length=262, Percent_Identity=28.2442748091603, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17560332, Length=258, Percent_Identity=28.6821705426357, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17565030, Length=264, Percent_Identity=28.030303030303, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17551412, Length=273, Percent_Identity=29.6703296703297, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17559104, Length=257, Percent_Identity=26.8482490272374, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17561272, Length=257, Percent_Identity=29.1828793774319, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17562990, Length=263, Percent_Identity=29.277566539924, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17555612, Length=213, Percent_Identity=32.3943661971831, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17567345, Length=214, Percent_Identity=27.1028037383178, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17564282, Length=196, Percent_Identity=27.5510204081633, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17536651, Length=253, Percent_Identity=27.2727272727273, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17508651, Length=261, Percent_Identity=27.2030651340996, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=268, Percent_Identity=27.6119402985075, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=197, Percent_Identity=24.3654822335025, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17544670, Length=262, Percent_Identity=25.9541984732824, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=261, Percent_Identity=26.4367816091954, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71994600, Length=252, Percent_Identity=27.3809523809524, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI72000259, Length=259, Percent_Identity=25.4826254826255, Blast_Score=70, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI71982365, Length=191, Percent_Identity=30.3664921465969, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17538486, Length=265, Percent_Identity=26.4150943396226, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71997099, Length=211, Percent_Identity=31.2796208530806, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17536025, Length=253, Percent_Identity=27.6679841897233, Blast_Score=67, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6322226, Length=193, Percent_Identity=28.4974093264249, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24639444, Length=246, Percent_Identity=34.5528455284553, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI21355319, Length=251, Percent_Identity=33.8645418326693, Blast_Score=116, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24643142, Length=249, Percent_Identity=30.1204819277108, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI28571526, Length=251, Percent_Identity=32.2709163346614, Blast_Score=98, Evalue=6e-21,
Organism=Drosophila melanogaster, GI23397609, Length=245, Percent_Identity=31.8367346938775, Blast_Score=97, Evalue=8e-21,
Organism=Drosophila melanogaster, GI21357041, Length=255, Percent_Identity=31.7647058823529, Blast_Score=95, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24644339, Length=247, Percent_Identity=30.3643724696356, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI17737361, Length=254, Percent_Identity=29.5275590551181, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24640492, Length=194, Percent_Identity=26.2886597938144, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24641232, Length=213, Percent_Identity=31.4553990610329, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI18859837, Length=146, Percent_Identity=36.3013698630137, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24644337, Length=197, Percent_Identity=29.4416243654822, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI116007234, Length=208, Percent_Identity=30.2884615384615, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24663911, Length=229, Percent_Identity=25.764192139738, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI161076371, Length=204, Percent_Identity=27.9411764705882, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100 [C]

Molecular weight: Translated: 25022; Mature: 24890

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQSLHGKTAIVTGSSRGIGRAIAEGLAAEGAAVVVNYVGNQKAADEVVAGIAGKGGKAI
CCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCCCCEE
AIQADISSVSDVRRLFDETESRLGAIDIVVANVGVAVIKPLTEATEADFDLVFGTNAKGT
EEEECHHHHHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHHCCCCEEEEECCCCCCC
FFTLQEAARRVRDGGRIIAVSTGGTKMFFTQTALYLGSKGAVEQFVRVLSRELGSRGITV
EEEHHHHHHHHHCCCEEEEEECCCCEEEEEHHHHHHCCCHHHHHHHHHHHHHHCCCCEEE
NALSPGFTDTDLLPERDRAVAAGMSPFGRIGAPHDVADVAVFLASDEARWLTGDNIQAGG
EECCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCHHHEEEEEECCCCCEEECCCCCCCC
GVA
CCC
>Mature Secondary Structure 
SQSLHGKTAIVTGSSRGIGRAIAEGLAAEGAAVVVNYVGNQKAADEVVAGIAGKGGKAI
CCCCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCCCCEE
AIQADISSVSDVRRLFDETESRLGAIDIVVANVGVAVIKPLTEATEADFDLVFGTNAKGT
EEEECHHHHHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHHCCCCEEEEECCCCCCC
FFTLQEAARRVRDGGRIIAVSTGGTKMFFTQTALYLGSKGAVEQFVRVLSRELGSRGITV
EEEHHHHHHHHHCCCEEEEEECCCCEEEEEHHHHHHCCCHHHHHHHHHHHHHHCCCCEEE
NALSPGFTDTDLLPERDRAVAAGMSPFGRIGAPHDVADVAVFLASDEARWLTGDNIQAGG
EECCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCHHHEEEEEECCCCCEEECCCCCCCC
GVA
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]

Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8868443 [H]