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The map label for this gene is kup1

Identifier: 13471444

GI number: 13471444

Start: 1180750

End: 1182669

Strand: Reverse

Name: kup1

Synonym: mll1416

Alternate gene names: 13471444

Gene position: 1182669-1180750 (Counterclockwise)

Preceding gene: 13471445

Following gene: 13471443

Centisome position: 16.81

GC content: 61.61

Gene sequence:

>1920_bases
ATGGCCCTTGCCAACACTGGTAGTGAGGCAGAACCCGTCGAACAGTCGAGCCATCCGGAAATCGAACAGCATAGCACCAA
GGTGCTGATGCTGGGCGCGCTGGGCGTTGTCTACGGCGATATCGGCACCAGCCCGATCTATGCCTTTCGCGAGGCGCTGG
TGGCGTCGTCTCACGGCACCGTCGCGCAACGCGGCGATATCCTTGGCGTGCTGTCGCTGATCATCTGGTCGCTGACGATC
ATCGTCACCATCAAATACATCATGTTCGTGCTGCGCGCCGACAACCGCGGTGAGGGCGGCGTGCTGTCGCTGATGGCGCT
GGCGCGCGGCAGTTTCCCGAAGCGCTCGGCGGTGATCCTGGGCATCGGCATTGTCGGCGCCTCGCTGTTTTTCGGCGATG
CGGTCATCACGCCGGCGATTTCGGTGCTGTCGGCGGTCGAAGGCATGAATGTCGTCACCCCCACCTTCCAGCCCTATGTC
GTGCCGCTGACACTTGTGATTCTCGCCGTGGTGTTCGCGGTGCAACGTTTCGGCACGGGCGGTGTGGGACTGGTCTTCGG
TCCGGTGACCGCGGTCTGGTTCCTGGCGATCGGTCTTTCGGGCCTCAAGCACATCATCGCCGATCCGGAAATCCTTTGGG
CGATCAGCCCGCACTACATCGTCGCCTTCCTGATTCATTCGCCCGACGTCGCCTTCGTCACCATCGGCGCCATCTTCCTG
GCTGTCACCGGCGCCGAGGCGCTTTATGCCGATCTCGGCCATTTCGGACGCAAGCCCATCGTGCTTGCCTGGCTGTCGAT
CGTGTTTCCCTGTCTGCTGCTGAACTATGCCGGGCAGGGCGCCTTCGTGCTGGCCAAGAATGGCGTCGTCGGTCATCCGT
TCTTCGAGATGAACGAGGGCTGGGCACTGATCCCGATGGTGGTGCTGGCGACCGCCGCGACGGTCATCGCCAGTCAGGCT
GTGATTTCGGGTGCCTTCTCGCTGACCAGGCAGGCAGTGCAGCTCAACATGCTGCCGCGCCTCGAAATCCTGCACACCTC
GGAAAAACAGTCCGGCCAGATCTACATGCCGCGTGTCAACCTTCTGCTGGCATTGGTGGTGATGATGCTGGTGGTCGGCT
TCGGCGAGTCCAGCAAGCTCGCCTCTGCCTATGGCATCTCGGTGACCGGCAACATGCTGGTGACGACGGTGCTGCTCTAT
GTCGTGATGACCCGCATCTGGAAATGGCGGCTCTGGGTTGCGATCAGCTTGACGGTGCTGTTTGCCTTCATCGATATCGG
CTTCTTCGCTTCCAACATCGTCAAGGTGTTCGAAGGCGGCTGGGCGTCATTGCTGGTGGCCTTCACAATCGTGCTGGGTA
TGTGGACCTGGGTGCGCGGCAGCCGCTATCTGTTCGACAAGACCCGCCGCAACGAGATCCCGCTCGATTTCCTCGCCGGC
AATCTGTTGAAGAAGAAGCCGCAGCTTGTATCCGGCACCGCGGTGTTCCTGACCAGCGATCCCTTGAGTGCACCGACAGC
GCTGATGCACAGCCTGAAGCACTACAAGGTGCTGCATGAGCAGAACGTCATCCTTTCGGTGGTGACTGCGCCACAGCCGG
TGGTGCCCGACAGCGACCGGGTCAAGATGGAGACGGTCAACGAGCTGTTCATGCGGGTGACGCTGACTTTCGGCTACATG
GAACAGCCCAACATTCCGCGCGCGCTGGCGATCTGCCGCAAGCAGGGCTGGAAGTTCGACATCATGACGACGTCGTTCTT
CCTGTCGCGGCGTTCGCTCAAGGCTTCGCCCAATTCCGGCATGCCGGTGTGGCAGGACCGACTGTTCATCGGGCTGGCGC
GTACGGCGGCCGACGCGACCGAGTATTTCCAGATCCCTACCGGGCGTGTGGTAGAGATCGGCACGCAGGTGGCGATCTGA

Upstream 100 bases:

>100_bases
AAGGAGCCTAGCGTTGCCAACATGGGAGCCATCACGCTACGGCACTTGATATTGCATTGCAGCAAGCGTAGAGCACCGCG
CGCTTATCGGAGTGTCGTCC

Downstream 100 bases:

>100_bases
CAAGCTCGATCGCCTTGCTTGTCACCGGCGGATCTGGCTTCCTCGGCGCGCACTGTGTCCTTGCCCTGCTGAACGCGGGC
CACCGCGTGCGCACCACGGT

Product: potassium uptake protein Kup

Products: K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 639; Mature: 638

Protein sequence:

>639_residues
MALANTGSEAEPVEQSSHPEIEQHSTKVLMLGALGVVYGDIGTSPIYAFREALVASSHGTVAQRGDILGVLSLIIWSLTI
IVTIKYIMFVLRADNRGEGGVLSLMALARGSFPKRSAVILGIGIVGASLFFGDAVITPAISVLSAVEGMNVVTPTFQPYV
VPLTLVILAVVFAVQRFGTGGVGLVFGPVTAVWFLAIGLSGLKHIIADPEILWAISPHYIVAFLIHSPDVAFVTIGAIFL
AVTGAEALYADLGHFGRKPIVLAWLSIVFPCLLLNYAGQGAFVLAKNGVVGHPFFEMNEGWALIPMVVLATAATVIASQA
VISGAFSLTRQAVQLNMLPRLEILHTSEKQSGQIYMPRVNLLLALVVMMLVVGFGESSKLASAYGISVTGNMLVTTVLLY
VVMTRIWKWRLWVAISLTVLFAFIDIGFFASNIVKVFEGGWASLLVAFTIVLGMWTWVRGSRYLFDKTRRNEIPLDFLAG
NLLKKKPQLVSGTAVFLTSDPLSAPTALMHSLKHYKVLHEQNVILSVVTAPQPVVPDSDRVKMETVNELFMRVTLTFGYM
EQPNIPRALAICRKQGWKFDIMTTSFFLSRRSLKASPNSGMPVWQDRLFIGLARTAADATEYFQIPTGRVVEIGTQVAI

Sequences:

>Translated_639_residues
MALANTGSEAEPVEQSSHPEIEQHSTKVLMLGALGVVYGDIGTSPIYAFREALVASSHGTVAQRGDILGVLSLIIWSLTI
IVTIKYIMFVLRADNRGEGGVLSLMALARGSFPKRSAVILGIGIVGASLFFGDAVITPAISVLSAVEGMNVVTPTFQPYV
VPLTLVILAVVFAVQRFGTGGVGLVFGPVTAVWFLAIGLSGLKHIIADPEILWAISPHYIVAFLIHSPDVAFVTIGAIFL
AVTGAEALYADLGHFGRKPIVLAWLSIVFPCLLLNYAGQGAFVLAKNGVVGHPFFEMNEGWALIPMVVLATAATVIASQA
VISGAFSLTRQAVQLNMLPRLEILHTSEKQSGQIYMPRVNLLLALVVMMLVVGFGESSKLASAYGISVTGNMLVTTVLLY
VVMTRIWKWRLWVAISLTVLFAFIDIGFFASNIVKVFEGGWASLLVAFTIVLGMWTWVRGSRYLFDKTRRNEIPLDFLAG
NLLKKKPQLVSGTAVFLTSDPLSAPTALMHSLKHYKVLHEQNVILSVVTAPQPVVPDSDRVKMETVNELFMRVTLTFGYM
EQPNIPRALAICRKQGWKFDIMTTSFFLSRRSLKASPNSGMPVWQDRLFIGLARTAADATEYFQIPTGRVVEIGTQVAI
>Mature_638_residues
ALANTGSEAEPVEQSSHPEIEQHSTKVLMLGALGVVYGDIGTSPIYAFREALVASSHGTVAQRGDILGVLSLIIWSLTII
VTIKYIMFVLRADNRGEGGVLSLMALARGSFPKRSAVILGIGIVGASLFFGDAVITPAISVLSAVEGMNVVTPTFQPYVV
PLTLVILAVVFAVQRFGTGGVGLVFGPVTAVWFLAIGLSGLKHIIADPEILWAISPHYIVAFLIHSPDVAFVTIGAIFLA
VTGAEALYADLGHFGRKPIVLAWLSIVFPCLLLNYAGQGAFVLAKNGVVGHPFFEMNEGWALIPMVVLATAATVIASQAV
ISGAFSLTRQAVQLNMLPRLEILHTSEKQSGQIYMPRVNLLLALVVMMLVVGFGESSKLASAYGISVTGNMLVTTVLLYV
VMTRIWKWRLWVAISLTVLFAFIDIGFFASNIVKVFEGGWASLLVAFTIVLGMWTWVRGSRYLFDKTRRNEIPLDFLAGN
LLKKKPQLVSGTAVFLTSDPLSAPTALMHSLKHYKVLHEQNVILSVVTAPQPVVPDSDRVKMETVNELFMRVTLTFGYME
QPNIPRALAICRKQGWKFDIMTTSFFLSRRSLKASPNSGMPVWQDRLFIGLARTAADATEYFQIPTGRVVEIGTQVAI

Specific function: Transport of potassium into the cell

COG id: COG3158

COG function: function code P; K+ transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAK/KUP transporter (TC 2.A.72) family

Homologues:

Organism=Escherichia coli, GI48994960, Length=619, Percent_Identity=43.1340872374798, Blast_Score=519, Evalue=1e-148,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KUP1_RHILO (Q98KL8)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_103010.1
- GeneID:   1225673
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mll1416
- NMPDR:   fig|266835.1.peg.1115
- HOGENOM:   HBG351154
- OMA:   ANSEHAS
- ProtClustDB:   CLSK863270
- HAMAP:   MF_01522
- InterPro:   IPR003855
- InterPro:   IPR023051

Pfam domain/function: PF02705 K_trans

EC number: NA

Molecular weight: Translated: 69324; Mature: 69193

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xe362e94)-; HASH(0xe085f58)-; HASH(0xe518d6c)-; HASH(0xe51a350)-; HASH(0xe0e4f94)-; HASH(0xd536aec)-; HASH(0xb582064)-; HASH(0xe518e8c)-; HASH(0xe08e7b8)-; HASH(0xe515144)-; HASH(0xe51a128)-; HASH(0xe3c5fe0)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALANTGSEAEPVEQSSHPEIEQHSTKVLMLGALGVVYGDIGTSPIYAFREALVASSHGT
CCCCCCCCCCCCCCCCCCCCHHHCCCEEEEEEHHHHHHCCCCCCHHHHHHHHHHHCCCCC
VAQRGDILGVLSLIIWSLTIIVTIKYIMFVLRADNRGEGGVLSLMALARGSFPKRSAVIL
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCEEEE
GIGIVGASLFFGDAVITPAISVLSAVEGMNVVTPTFQPYVVPLTLVILAVVFAVQRFGTG
EHHHHHHHHHHCHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHCCCC
GVGLVFGPVTAVWFLAIGLSGLKHIIADPEILWAISPHYIVAFLIHSPDVAFVTIGAIFL
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHEEEEEEECCCCHHHHHHHHHH
AVTGAEALYADLGHFGRKPIVLAWLSIVFPCLLLNYAGQGAFVLAKNGVVGHPFFEMNEG
HHHCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEECCCC
WALIPMVVLATAATVIASQAVISGAFSLTRQAVQLNMLPRLEILHTSEKQSGQIYMPRVN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEECHHH
LLLALVVMMLVVGFGESSKLASAYGISVTGNMLVTTVLLYVVMTRIWKWRLWVAISLTVL
HHHHHHHHHHHHCCCCCCCHHHHCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FAFIDIGFFASNIVKVFEGGWASLLVAFTIVLGMWTWVRGSRYLFDKTRRNEIPLDFLAG
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHH
NLLKKKPQLVSGTAVFLTSDPLSAPTALMHSLKHYKVLHEQNVILSVVTAPQPVVPDSDR
HHHHCCCCEECCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCC
VKMETVNELFMRVTLTFGYMEQPNIPRALAICRKQGWKFDIMTTSFFLSRRSLKASPNSG
CHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCEEEEEHHHHHHHHHHCCCCCCCC
MPVWQDRLFIGLARTAADATEYFQIPTGRVVEIGTQVAI
CCCHHHHHHHHHHHHHHCCHHHEECCCCCEEECCCEECH
>Mature Secondary Structure 
ALANTGSEAEPVEQSSHPEIEQHSTKVLMLGALGVVYGDIGTSPIYAFREALVASSHGT
CCCCCCCCCCCCCCCCCCCHHHCCCEEEEEEHHHHHHCCCCCCHHHHHHHHHHHCCCCC
VAQRGDILGVLSLIIWSLTIIVTIKYIMFVLRADNRGEGGVLSLMALARGSFPKRSAVIL
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCEEEE
GIGIVGASLFFGDAVITPAISVLSAVEGMNVVTPTFQPYVVPLTLVILAVVFAVQRFGTG
EHHHHHHHHHHCHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHCCCC
GVGLVFGPVTAVWFLAIGLSGLKHIIADPEILWAISPHYIVAFLIHSPDVAFVTIGAIFL
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHEEEEEEECCCCHHHHHHHHHH
AVTGAEALYADLGHFGRKPIVLAWLSIVFPCLLLNYAGQGAFVLAKNGVVGHPFFEMNEG
HHHCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEECCCC
WALIPMVVLATAATVIASQAVISGAFSLTRQAVQLNMLPRLEILHTSEKQSGQIYMPRVN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEECHHH
LLLALVVMMLVVGFGESSKLASAYGISVTGNMLVTTVLLYVVMTRIWKWRLWVAISLTVL
HHHHHHHHHHHHCCCCCCCHHHHCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FAFIDIGFFASNIVKVFEGGWASLLVAFTIVLGMWTWVRGSRYLFDKTRRNEIPLDFLAG
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHH
NLLKKKPQLVSGTAVFLTSDPLSAPTALMHSLKHYKVLHEQNVILSVVTAPQPVVPDSDR
HHHHCCCCEECCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCC
VKMETVNELFMRVTLTFGYMEQPNIPRALAICRKQGWKFDIMTTSFFLSRRSLKASPNSG
CHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCEEEEEHHHHHHHHHHCCCCCCCC
MPVWQDRLFIGLARTAADATEYFQIPTGRVVEIGTQVAI
CCCHHHHHHHHHHHHHHCCHHHEECCCCCEEECCCEECH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11214968