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The map label for this gene is kup2

Identifier: 13471445

GI number: 13471445

Start: 1182856

End: 1184769

Strand: Reverse

Name: kup2

Synonym: mll1417

Alternate gene names: 13471445

Gene position: 1184769-1182856 (Counterclockwise)

Preceding gene: 13471446

Following gene: 13471444

Centisome position: 16.84

GC content: 59.77

Gene sequence:

>1914_bases
ATGGACCTTGCCAGTCGCGATAGCGAGGCCGAAACCGTCGAGCAATCGAGCCATTCCGGGGCCGAACAGCACAGCACCAA
AGTTCTTATGCTGGGTGCGCTCGGCGTTGTCTATGGCGATATCGGCACCAGTCCGATCTACGCTTTCCGTGAGGCGCTTC
ACGCTTCGCCCGGTATCGATACGCGCGCTCAGGTGCTTGGTGTACTGTCGCTGATCGTCTGGGCGCTAACGATCATCGTG
ACGATAAAATATGTCGCCTTCGTACTTCGCGCCGACAATAAGGGCGAAGGCGGTACGTTGTCGCTGATGTCGCTGGCGCG
AACCGCCTATCCCAAAGGTGCGCGACTTATTCTGGCAATCGGCCTTTGCGGCGCGGCGTTGTTTTTCGGCGATTCGATCA
TAACGCCGGCCATCTCCGTGCTGTCGGCGGTCGAAGGCCTCAGGGTGGTGACGCCGACACTGGACCCCTACGTCGTGCCG
ATCACGCTGCTCATCCTGGCCATTCTGTTCTCGGTGCAGCGCTTCGGCACGGGAAAGGTGGCGGCGGTGTTCGGGCCGGT
GACCGCACTATGGTTCCTGGCTATCGGCGTAGCAGGGCTCTATCACCTGTTGGACGATCCATCGATCCTGCTGGCCATCA
ATCCCTATTACGCGGTCACCTATCTCGCCAGCACACCCACGGCCGCCTTTGTCACTGTCGGCGCGGTGTTCCTGGCGGTG
ACCGGGGCCGAGGCACTTTATGTCGATCTCGGCCATTTTGGGCGCAAGCCTATCGTGTTGGCGTGGTTTTCCGTGGTTTT
CCCATGCCTGCTGCTCAACTATTTCGGGCAAGGTGCTTTTGTGCTGGCCAATGGCGGGAGGCCGACCAATCCATTCTTCC
AGATGCTGCCCGACTGGGCACTGATGCCGATGGTGGGGCTGGCGACGGCCGCAACCGTCATCGCTAGCCAGGCAGTCATA
TCAGGTGCTTTTTCGCTGACCCGCCAGGCAGTGCAGCTCAACCTTCTGCCACGCATAGAGGTGCAGCATACGTCCGAAAT
GCAACTCGGCCAGATCTACATGCCCCGCATCAATCTGCTCGTCGCTCTGGGGGTGATGCTGCTGGTCGTCGGTTTCGGCA
GTTCGAGTTCGCTGGCTTCCGCCTACGGCATCTCGGTGACCGGCGAAATGCTGATGACGACGATCCTTTTGTTCGTCGTC
ATGCGCAAGCTGTGGAAATGGAGGCTGGCGGTCGCGCTGCCGCTGACATTGCTGTTCGGCATCATCGACAGCGGCTTCTT
CCTGGCAAACATCGTAAAGATATTCGAAGGCGGCTGGGTATCGATCACGGTTGCCTGCCTGATGGGGCTGATCATGTGGA
CCTGGATACGCGGCACGCGCTATCTGTTCGACAAGACCCGCCGCAACGAAATCCCGCTCGATTTTCTTGCCGCCAATCTG
TTGAAGAAGAAGCCGCACCTGGTGCCAGGCACGGCTGTGTTCCTGACCAGCGATCCCTTGAGTGCACCGACAGCGCTGAT
GCACAGCCTGAAGCACTACAAGGTGCTGCATGAGCAGAACGTCATCCTTTCGGTGGTGACGGCGCCACAGCCGGTGGTAT
CAGACAGCGACCGGGTCAAGATGGAGACGGTCAACGACCTGTTCATGCGGGTGACGCTGACCTTCGGCTATATGGAACAG
CCCAACATTCCGCGCGCGCTGGCGATCTGCCGCAAGCGGGGCTGGAAGTTCGACATCATGACGACATCGTTTTTCCTGTC
GCGGCGTTCGCTCAAGGCCTCGCCCAATTCCGGCATGCCGGTGTGGCAGGACAGGCTGTTCATCGGCCTGGCCCGCACGG
CGGCCGATGCAACCGAATATTTCCAGATCCCGACCGGACGTGTCGTGGAAATCGGCACGCAAGTCGCTATCTAA

Upstream 100 bases:

>100_bases
AAGGGTAGAGTTTCGCCTTGCAGGTATGGCAGCCATAGCGTGCAACTGACATCGCATCGTAGCATGCGTGAAGCACCGCG
CGCTCGTCGGGGAGTGGTCT

Downstream 100 bases:

>100_bases
AGGCGGATATGGCAGCTTTTATGGGCGCCCTCCATGCCCCACGGCCGCGAATTCAGCCCGCGACCATTGGATTACGGCCA
TTTCCCAAGGAGCCTAGCGT

Product: potassium uptake protein Kup

Products: K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 637; Mature: 637

Protein sequence:

>637_residues
MDLASRDSEAETVEQSSHSGAEQHSTKVLMLGALGVVYGDIGTSPIYAFREALHASPGIDTRAQVLGVLSLIVWALTIIV
TIKYVAFVLRADNKGEGGTLSLMSLARTAYPKGARLILAIGLCGAALFFGDSIITPAISVLSAVEGLRVVTPTLDPYVVP
ITLLILAILFSVQRFGTGKVAAVFGPVTALWFLAIGVAGLYHLLDDPSILLAINPYYAVTYLASTPTAAFVTVGAVFLAV
TGAEALYVDLGHFGRKPIVLAWFSVVFPCLLLNYFGQGAFVLANGGRPTNPFFQMLPDWALMPMVGLATAATVIASQAVI
SGAFSLTRQAVQLNLLPRIEVQHTSEMQLGQIYMPRINLLVALGVMLLVVGFGSSSSLASAYGISVTGEMLMTTILLFVV
MRKLWKWRLAVALPLTLLFGIIDSGFFLANIVKIFEGGWVSITVACLMGLIMWTWIRGTRYLFDKTRRNEIPLDFLAANL
LKKKPHLVPGTAVFLTSDPLSAPTALMHSLKHYKVLHEQNVILSVVTAPQPVVSDSDRVKMETVNDLFMRVTLTFGYMEQ
PNIPRALAICRKRGWKFDIMTTSFFLSRRSLKASPNSGMPVWQDRLFIGLARTAADATEYFQIPTGRVVEIGTQVAI

Sequences:

>Translated_637_residues
MDLASRDSEAETVEQSSHSGAEQHSTKVLMLGALGVVYGDIGTSPIYAFREALHASPGIDTRAQVLGVLSLIVWALTIIV
TIKYVAFVLRADNKGEGGTLSLMSLARTAYPKGARLILAIGLCGAALFFGDSIITPAISVLSAVEGLRVVTPTLDPYVVP
ITLLILAILFSVQRFGTGKVAAVFGPVTALWFLAIGVAGLYHLLDDPSILLAINPYYAVTYLASTPTAAFVTVGAVFLAV
TGAEALYVDLGHFGRKPIVLAWFSVVFPCLLLNYFGQGAFVLANGGRPTNPFFQMLPDWALMPMVGLATAATVIASQAVI
SGAFSLTRQAVQLNLLPRIEVQHTSEMQLGQIYMPRINLLVALGVMLLVVGFGSSSSLASAYGISVTGEMLMTTILLFVV
MRKLWKWRLAVALPLTLLFGIIDSGFFLANIVKIFEGGWVSITVACLMGLIMWTWIRGTRYLFDKTRRNEIPLDFLAANL
LKKKPHLVPGTAVFLTSDPLSAPTALMHSLKHYKVLHEQNVILSVVTAPQPVVSDSDRVKMETVNDLFMRVTLTFGYMEQ
PNIPRALAICRKRGWKFDIMTTSFFLSRRSLKASPNSGMPVWQDRLFIGLARTAADATEYFQIPTGRVVEIGTQVAI
>Mature_637_residues
MDLASRDSEAETVEQSSHSGAEQHSTKVLMLGALGVVYGDIGTSPIYAFREALHASPGIDTRAQVLGVLSLIVWALTIIV
TIKYVAFVLRADNKGEGGTLSLMSLARTAYPKGARLILAIGLCGAALFFGDSIITPAISVLSAVEGLRVVTPTLDPYVVP
ITLLILAILFSVQRFGTGKVAAVFGPVTALWFLAIGVAGLYHLLDDPSILLAINPYYAVTYLASTPTAAFVTVGAVFLAV
TGAEALYVDLGHFGRKPIVLAWFSVVFPCLLLNYFGQGAFVLANGGRPTNPFFQMLPDWALMPMVGLATAATVIASQAVI
SGAFSLTRQAVQLNLLPRIEVQHTSEMQLGQIYMPRINLLVALGVMLLVVGFGSSSSLASAYGISVTGEMLMTTILLFVV
MRKLWKWRLAVALPLTLLFGIIDSGFFLANIVKIFEGGWVSITVACLMGLIMWTWIRGTRYLFDKTRRNEIPLDFLAANL
LKKKPHLVPGTAVFLTSDPLSAPTALMHSLKHYKVLHEQNVILSVVTAPQPVVSDSDRVKMETVNDLFMRVTLTFGYMEQ
PNIPRALAICRKRGWKFDIMTTSFFLSRRSLKASPNSGMPVWQDRLFIGLARTAADATEYFQIPTGRVVEIGTQVAI

Specific function: Transport of potassium into the cell

COG id: COG3158

COG function: function code P; K+ transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAK/KUP transporter (TC 2.A.72) family

Homologues:

Organism=Escherichia coli, GI48994960, Length=621, Percent_Identity=44.2834138486312, Blast_Score=530, Evalue=1e-151,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KUP2_RHILO (Q98KL7)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_103011.1
- GeneID:   1225674
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mll1417
- NMPDR:   fig|266835.1.peg.1116
- HOGENOM:   HBG351154
- OMA:   LPRFEIR
- ProtClustDB:   CLSK863270
- HAMAP:   MF_01522
- InterPro:   IPR003855
- InterPro:   IPR023051

Pfam domain/function: PF02705 K_trans

EC number: NA

Molecular weight: Translated: 69094; Mature: 69094

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xd19bf80)-; HASH(0xe3f8154)-; HASH(0xdaec7dc)-; HASH(0xdce2eb0)-; HASH(0xd665368)-; HASH(0xbc9abb8)-; HASH(0xe3d7abc)-; HASH(0xdebf808)-; HASH(0xde62cb8)-; HASH(0xdaeb560)-; HASH(0xdbe1b78)-; HASH(0xdf8b9d4)-;

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLASRDSEAETVEQSSHSGAEQHSTKVLMLGALGVVYGDIGTSPIYAFREALHASPGID
CCCCCCCCHHHHHHHHCCCCCHHHCCEEEEEEHHHHHHCCCCCCHHHHHHHHHHCCCCCC
TRAQVLGVLSLIVWALTIIVTIKYVAFVLRADNKGEGGTLSLMSLARTAYPKGARLILAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEH
GLCGAALFFGDSIITPAISVLSAVEGLRVVTPTLDPYVVPITLLILAILFSVQRFGTGKV
HHHHHHHHHCCHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCH
AAVFGPVTALWFLAIGVAGLYHLLDDPSILLAINPYYAVTYLASTPTAAFVTVGAVFLAV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCCCHHHHHHHHHHHHH
TGAEALYVDLGHFGRKPIVLAWFSVVFPCLLLNYFGQGAFVLANGGRPTNPFFQMLPDWA
CCCCEEEEEHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHCCCHH
LMPMVGLATAATVIASQAVISGAFSLTRQAVQLNLLPRIEVQHTSEMQLGQIYMPRINLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEECCCCCCCCCCEEHHHHHHH
VALGVMLLVVGFGSSSSLASAYGISVTGEMLMTTILLFVVMRKLWKWRLAVALPLTLLFG
HHHHHHHHHHCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IIDSGFFLANIVKIFEGGWVSITVACLMGLIMWTWIRGTRYLFDKTRRNEIPLDFLAANL
HHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHH
LKKKPHLVPGTAVFLTSDPLSAPTALMHSLKHYKVLHEQNVILSVVTAPQPVVSDSDRVK
HHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCEE
METVNDLFMRVTLTFGYMEQPNIPRALAICRKRGWKFDIMTTSFFLSRRSLKASPNSGMP
HHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHCCCEEEEEHHHHHHHHHHCCCCCCCCCC
VWQDRLFIGLARTAADATEYFQIPTGRVVEIGTQVAI
CHHHHHHHHHHHHHHCCHHHEECCCCCEEECCCEECH
>Mature Secondary Structure
MDLASRDSEAETVEQSSHSGAEQHSTKVLMLGALGVVYGDIGTSPIYAFREALHASPGID
CCCCCCCCHHHHHHHHCCCCCHHHCCEEEEEEHHHHHHCCCCCCHHHHHHHHHHCCCCCC
TRAQVLGVLSLIVWALTIIVTIKYVAFVLRADNKGEGGTLSLMSLARTAYPKGARLILAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEH
GLCGAALFFGDSIITPAISVLSAVEGLRVVTPTLDPYVVPITLLILAILFSVQRFGTGKV
HHHHHHHHHCCHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCH
AAVFGPVTALWFLAIGVAGLYHLLDDPSILLAINPYYAVTYLASTPTAAFVTVGAVFLAV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCCCHHHHHHHHHHHHH
TGAEALYVDLGHFGRKPIVLAWFSVVFPCLLLNYFGQGAFVLANGGRPTNPFFQMLPDWA
CCCCEEEEEHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHCCCHH
LMPMVGLATAATVIASQAVISGAFSLTRQAVQLNLLPRIEVQHTSEMQLGQIYMPRINLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEECCCCCCCCCCEEHHHHHHH
VALGVMLLVVGFGSSSSLASAYGISVTGEMLMTTILLFVVMRKLWKWRLAVALPLTLLFG
HHHHHHHHHHCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IIDSGFFLANIVKIFEGGWVSITVACLMGLIMWTWIRGTRYLFDKTRRNEIPLDFLAANL
HHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHH
LKKKPHLVPGTAVFLTSDPLSAPTALMHSLKHYKVLHEQNVILSVVTAPQPVVSDSDRVK
HHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCEE
METVNDLFMRVTLTFGYMEQPNIPRALAICRKRGWKFDIMTTSFFLSRRSLKASPNSGMP
HHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHCCCEEEEEHHHHHHHHHHCCCCCCCCCC
VWQDRLFIGLARTAADATEYFQIPTGRVVEIGTQVAI
CHHHHHHHHHHHHHHCCHHHEECCCCCEEECCCEECH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11214968