Click here to switch to the map view.

The map label for this gene is nuoC

Identifier: 13471405

GI number: 13471405

Start: 1146012

End: 1146617

Strand: Reverse

Name: nuoC

Synonym: mll1369

Alternate gene names: 13471405

Gene position: 1146617-1146012 (Counterclockwise)

Preceding gene: 13471406

Following gene: 13471404

Centisome position: 16.3

GC content: 58.58

Gene sequence:

>606_bases
ATGGCCGCATCCCTTAGCGAACTGTCGACCTATCTCGGCGAAAGGCTGATTGGTCGCGTCAACGACGCTGATATCGCCTA
TGGCGAGCTCACCATGCATGTCGAGCCGCGCAACCTCATCGAAGTCGTGACCTTCCTGCGCGACGATCAGCGCTGCCAGT
TCATCTCGATCATCGATGTCTGCGGTGCTGACTATCCGTCGCGGCCCAAGCGCTTCGACGTCGTCTATCACCTGCTTTCG
CCGAAGCAGAATGTGCGCATCCGGCTCAAGGTGCAGGCCGACGAGGAGACGATGGTGCCGTCGATCACCGGTGTATTCCC
GGGGGCCGACTGGTTCGAGCGCGAGACCTACGATCTCTATGGCGTGCTGTTCTCCGGCCATCCCGATCTGCGCCGCCTTT
TGACCGACTACGGTTTCGAAGGCCATCCGCTGCGCAAGGATTTCCCGCTGACCGGTTTTGTCGAAGTGCGTTACGACGAC
GAAGCCAAGCGCGTCATCTACGAGCCGGTCGAGCTCAAGCAGGAATTCCGCAATTTCGATTTTCTCTCGCCATGGGAAGG
GACGGATTACGTTCTGCCTGGCGATGAAAAAGCCAAGACGAATTGA

Upstream 100 bases:

>100_bases
TATGTGCCCGGCTGCCCGCCGAGCGCCGAAGCTTTGCTCTACGGCATTCTTCTCCTGCAGAAGAAAATCCGCCGCACCGG
CACGATCGAACGGTAAATCC

Downstream 100 bases:

>100_bases
GGCGCCACAATGGCTGAGACCTCCGTCCGCAATTTCAACATCAACTTCGGCCCGCAACACCCTGCGGCGCACGGCGTTTT
GCGCCTCGTTCTGGAGCTCG

Product: NADH dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C

Number of amino acids: Translated: 201; Mature: 200

Protein sequence:

>201_residues
MAASLSELSTYLGERLIGRVNDADIAYGELTMHVEPRNLIEVVTFLRDDQRCQFISIIDVCGADYPSRPKRFDVVYHLLS
PKQNVRIRLKVQADEETMVPSITGVFPGADWFERETYDLYGVLFSGHPDLRRLLTDYGFEGHPLRKDFPLTGFVEVRYDD
EAKRVIYEPVELKQEFRNFDFLSPWEGTDYVLPGDEKAKTN

Sequences:

>Translated_201_residues
MAASLSELSTYLGERLIGRVNDADIAYGELTMHVEPRNLIEVVTFLRDDQRCQFISIIDVCGADYPSRPKRFDVVYHLLS
PKQNVRIRLKVQADEETMVPSITGVFPGADWFERETYDLYGVLFSGHPDLRRLLTDYGFEGHPLRKDFPLTGFVEVRYDD
EAKRVIYEPVELKQEFRNFDFLSPWEGTDYVLPGDEKAKTN
>Mature_200_residues
AASLSELSTYLGERLIGRVNDADIAYGELTMHVEPRNLIEVVTFLRDDQRCQFISIIDVCGADYPSRPKRFDVVYHLLSP
KQNVRIRLKVQADEETMVPSITGVFPGADWFERETYDLYGVLFSGHPDLRRLLTDYGFEGHPLRKDFPLTGFVEVRYDDE
AKRVIYEPVELKQEFRNFDFLSPWEGTDYVLPGDEKAKTN

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family

Homologues:

Organism=Homo sapiens, GI4758788, Length=185, Percent_Identity=52.972972972973, Blast_Score=207, Evalue=5e-54,
Organism=Escherichia coli, GI145693162, Length=166, Percent_Identity=35.5421686746988, Blast_Score=99, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71990788, Length=183, Percent_Identity=50.2732240437158, Blast_Score=195, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI32563621, Length=183, Percent_Identity=50.2732240437158, Blast_Score=195, Evalue=1e-50,
Organism=Drosophila melanogaster, GI24656494, Length=185, Percent_Identity=50.8108108108108, Blast_Score=200, Evalue=4e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOC_RHILO (Q98KQ7)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_102971.1
- ProteinModelPortal:   Q98KQ7
- SMR:   Q98KQ7
- GeneID:   1225634
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mll1369
- NMPDR:   fig|266835.1.peg.1076
- HOGENOM:   HBG727675
- OMA:   VVYEPVR
- ProtClustDB:   PRK06074
- GO:   GO:0006810
- HAMAP:   MF_01357
- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581
- TIGRFAMs:   TIGR01961

Pfam domain/function: PF00329 Complex1_30kDa

EC number: =1.6.99.5

Molecular weight: Translated: 23248; Mature: 23116

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAASLSELSTYLGERLIGRVNDADIAYGELTMHVEPRNLIEVVTFLRDDQRCQFISIIDV
CCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCHHHHHHHHHHCCCCCCHHEEHHHH
CGADYPSRPKRFDVVYHLLSPKQNVRIRLKVQADEETMVPSITGVFPGADWFERETYDLY
HCCCCCCCCCHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCEECCCCCCHHHCCCCEEEE
GVLFSGHPDLRRLLTDYGFEGHPLRKDFPLTGFVEVRYDDEAKRVIYEPVELKQEFRNFD
EEEECCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCHHEEECCHHHHHHHHCCC
FLSPWEGTDYVLPGDEKAKTN
CCCCCCCCCEEECCCCCCCCC
>Mature Secondary Structure 
AASLSELSTYLGERLIGRVNDADIAYGELTMHVEPRNLIEVVTFLRDDQRCQFISIIDV
CCCHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCHHHHHHHHHHCCCCCCHHEEHHHH
CGADYPSRPKRFDVVYHLLSPKQNVRIRLKVQADEETMVPSITGVFPGADWFERETYDLY
HCCCCCCCCCHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCEECCCCCCHHHCCCCEEEE
GVLFSGHPDLRRLLTDYGFEGHPLRKDFPLTGFVEVRYDDEAKRVIYEPVELKQEFRNFD
EEEECCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCHHEEECCHHHHHHHHCCC
FLSPWEGTDYVLPGDEKAKTN
CCCCCCCCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11214968