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The map label for this gene is 13471391

Identifier: 13471391

GI number: 13471391

Start: 1129229

End: 1130899

Strand: Reverse

Name: 13471391

Synonym: mll1350

Alternate gene names: NA

Gene position: 1130899-1129229 (Counterclockwise)

Preceding gene: 13471392

Following gene: 13471389

Centisome position: 16.07

GC content: 65.23

Gene sequence:

>1671_bases
ATGGCGAAAGCGGAAAACGCCGAACTCGTCTTCGTGCCGCTCGGCGGCGTCGGCGAGATCGGCATGAACTTCGCCCTCTA
CGGCTACGGCCCGCCGAGTGCGCGCGAATGGATCGTCATCGATGTCGGCGTCACCTTTCCCGACGCGGCGCATCCGGGCG
TCGACCTGATCCTGCCCGACACGCGCTTCATCGAGGAAAACCTCGCCAATCTGCGTGGCATCATCATCACCCACGCGCAT
GAAGACCATTACGGCGCGCTGCTCGACACCTGGCCGAAGCTGAAGGCGCCGGTATGGATGACGCCGTTCAGTGCCGGGCT
GCTGGAAGCCAAGCGGCAGGGCGAGCAGGGGGCACCGAAGATTCCGCTTACGATCTATCGGGCCGGCGAGAAATTCACCG
TCGGTCCGTTCGAGATCGAAGCCATTCCGGTGGCGCACTCGATCCCCGAGCCGATGTCGCTGGCCATCACCACGCCGGCC
GGCACCGTCATCCACACCGGCGACTGGAAGATCGATCCTGAACCGACGATCGGGCCGAAGACCGACGAGGCGCGGTTTCG
TGCCTATGGCGACAAGGGCGTGCTGGCGCTGATCTGCGATTCGACCAATGCGCTGCGGGAAGGGGAATCACCGTCGGAAG
TGGCGGTTGGCGAGGGGCTCAAGGGCGTCATCCAGAGTGCCGTCGGCCGGGTCGCCGTGACAACCTTCTCCTCCAACGTC
GGGCGTATCGTCTCCATTGCCAAGGCGGCGCGCGATGCCGGCCGCCAGTGCCTGGTGCTCGGCCGCTCGCTGAAGCGCGT
CATCGATGTCGCCGACGAGCTCGGCTATATGGACGGCCTGCCGGAGTTCATTGCGGAGGAGGATTTCGGCTTCATCCCGC
GCGAAAACCTGGTCATCATCTGCACCGGCAGCCAGGGCGAGCCGCTGGCGGCGCTGGCGAAACTGTCGCGCGACGAGATG
AAATCGGTGTCGCTGACGGCGGGCGACACGGTGGTGTTTTCCTCACGCACCATTCCCGGCAACGAGAAGGCGATCCTCGA
GATCAAGAACCGCCTCATCGATCTCGGCATCAAGATCATCGAGGACGGCGACGCGCTGGTACATGTCTCCGGCCATCCCC
GGCGCAGCGAGTTGCGCAAGATGTATGAATGGGTGCGCCCGCAGATCGGCGTTCCCGTGCATGGCGAGGCGGCGCATCTG
GTGGCCCAGGGATCGCTGATGTCGACATCCGGCATCGGCCAGGTGGCGCAGGTGCGCGACGGCGACATGCTGCGGCTTGC
TCCCGGCCCCGCCACCATCATCGACCAGGTGCCGTTCGGCCGCATCTACAAGGACGGCAATCTGATCGGCACCGACCAGG
CGATGGGCATTCGCGACCGGCGCAAACTGTCCTTTGCCGGCCATGTCGCGGTCAATGTCGTGCTCGACGACAAATACGAA
CTGGCCGGTGATCCCGATCTGGTCGCCATCGGCGTCGCCGAGGCCGACGCCAGCGGCGAGACGCTGGAGGATCTGATGAT
CGATGCGGCCGTCGGTGCGGTCGATTCGATTCCCCGCCAGCGGCGCAAAGACCTCGACCTGGTTCAGGAAGCGGTGCGGC
GCGCGGTGCGCGGCGCTGCCAACGAAGCCTGGGGCAAGAAGCCACTGGTTACGGTTTTCGTCACCAGGTGA

Upstream 100 bases:

>100_bases
GGGGACTGTCCTGACGATCGCGGCCGGCGACGTGCATTTCGGCGCAGTGGCGTCCGCTCGGGTATAATGGGCTGGCCTGA
GGGCCAGGAAGGGAAAAATC

Downstream 100 bases:

>100_bases
GGGGCGGCAGCGGTTCGCTACCCGTTCAGCTGATAGCTGACCGGAAGCCAGCGAAAAGAACCGTTCACCGATTCGATGTA
GCCCAGGCCTGGAAACGGCA

Product: hypothetical protein

Products: NA

Alternate protein names: RNase J [H]

Number of amino acids: Translated: 556; Mature: 555

Protein sequence:

>556_residues
MAKAENAELVFVPLGGVGEIGMNFALYGYGPPSAREWIVIDVGVTFPDAAHPGVDLILPDTRFIEENLANLRGIIITHAH
EDHYGALLDTWPKLKAPVWMTPFSAGLLEAKRQGEQGAPKIPLTIYRAGEKFTVGPFEIEAIPVAHSIPEPMSLAITTPA
GTVIHTGDWKIDPEPTIGPKTDEARFRAYGDKGVLALICDSTNALREGESPSEVAVGEGLKGVIQSAVGRVAVTTFSSNV
GRIVSIAKAARDAGRQCLVLGRSLKRVIDVADELGYMDGLPEFIAEEDFGFIPRENLVIICTGSQGEPLAALAKLSRDEM
KSVSLTAGDTVVFSSRTIPGNEKAILEIKNRLIDLGIKIIEDGDALVHVSGHPRRSELRKMYEWVRPQIGVPVHGEAAHL
VAQGSLMSTSGIGQVAQVRDGDMLRLAPGPATIIDQVPFGRIYKDGNLIGTDQAMGIRDRRKLSFAGHVAVNVVLDDKYE
LAGDPDLVAIGVAEADASGETLEDLMIDAAVGAVDSIPRQRRKDLDLVQEAVRRAVRGAANEAWGKKPLVTVFVTR

Sequences:

>Translated_556_residues
MAKAENAELVFVPLGGVGEIGMNFALYGYGPPSAREWIVIDVGVTFPDAAHPGVDLILPDTRFIEENLANLRGIIITHAH
EDHYGALLDTWPKLKAPVWMTPFSAGLLEAKRQGEQGAPKIPLTIYRAGEKFTVGPFEIEAIPVAHSIPEPMSLAITTPA
GTVIHTGDWKIDPEPTIGPKTDEARFRAYGDKGVLALICDSTNALREGESPSEVAVGEGLKGVIQSAVGRVAVTTFSSNV
GRIVSIAKAARDAGRQCLVLGRSLKRVIDVADELGYMDGLPEFIAEEDFGFIPRENLVIICTGSQGEPLAALAKLSRDEM
KSVSLTAGDTVVFSSRTIPGNEKAILEIKNRLIDLGIKIIEDGDALVHVSGHPRRSELRKMYEWVRPQIGVPVHGEAAHL
VAQGSLMSTSGIGQVAQVRDGDMLRLAPGPATIIDQVPFGRIYKDGNLIGTDQAMGIRDRRKLSFAGHVAVNVVLDDKYE
LAGDPDLVAIGVAEADASGETLEDLMIDAAVGAVDSIPRQRRKDLDLVQEAVRRAVRGAANEAWGKKPLVTVFVTR
>Mature_555_residues
AKAENAELVFVPLGGVGEIGMNFALYGYGPPSAREWIVIDVGVTFPDAAHPGVDLILPDTRFIEENLANLRGIIITHAHE
DHYGALLDTWPKLKAPVWMTPFSAGLLEAKRQGEQGAPKIPLTIYRAGEKFTVGPFEIEAIPVAHSIPEPMSLAITTPAG
TVIHTGDWKIDPEPTIGPKTDEARFRAYGDKGVLALICDSTNALREGESPSEVAVGEGLKGVIQSAVGRVAVTTFSSNVG
RIVSIAKAARDAGRQCLVLGRSLKRVIDVADELGYMDGLPEFIAEEDFGFIPRENLVIICTGSQGEPLAALAKLSRDEMK
SVSLTAGDTVVFSSRTIPGNEKAILEIKNRLIDLGIKIIEDGDALVHVSGHPRRSELRKMYEWVRPQIGVPVHGEAAHLV
AQGSLMSTSGIGQVAQVRDGDMLRLAPGPATIIDQVPFGRIYKDGNLIGTDQAMGIRDRRKLSFAGHVAVNVVLDDKYEL
AGDPDLVAIGVAEADASGETLEDLMIDAAVGAVDSIPRQRRKDLDLVQEAVRRAVRGAANEAWGKKPLVTVFVTR

Specific function: Unknown

COG id: COG0595

COG function: function code R; Predicted hydrolase of the metallo-beta-lactamase superfamily

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. RNase J subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR011108
- InterPro:   IPR001587 [H]

Pfam domain/function: PF00753 Lactamase_B; PF07521 RMMBL [H]

EC number: NA

Molecular weight: Translated: 59661; Mature: 59530

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKAENAELVFVPLGGVGEIGMNFALYGYGPPSAREWIVIDVGVTFPDAAHPGVDLILPD
CCCCCCCCEEEEECCCCCCCCCCEEEEECCCCCCCEEEEEEECCCCCCCCCCCCEEEECC
TRFIEENLANLRGIIITHAHEDHYGALLDTWPKLKAPVWMTPFSAGLLEAKRQGEQGAPK
HHHHHHHHHCCCEEEEEECCCCCCCHHHHCCCCCCCCEEECCCHHHHHHHHHCCCCCCCC
IPLTIYRAGEKFTVGPFEIEAIPVAHSIPEPMSLAITTPAGTVIHTGDWKIDPEPTIGPK
CCEEEEECCCEEECCCEEEEEEECCCCCCCCCEEEEECCCCCEEECCCEEECCCCCCCCC
TDEARFRAYGDKGVLALICDSTNALREGESPSEVAVGEGLKGVIQSAVGRVAVTTFSSNV
CCCCCEEEECCCCEEEEEECCCHHHHCCCCCCCHHHCCCHHHHHHHHHCEEEEEEECCCC
GRIVSIAKAARDAGRQCLVLGRSLKRVIDVADELGYMDGLPEFIAEEDFGFIPRENLVII
HHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCEEEE
CTGSQGEPLAALAKLSRDEMKSVSLTAGDTVVFSSRTIPGNEKAILEIKNRLIDLGIKII
EECCCCCHHHHHHHHCHHHHHEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHCCEEEE
EDGDALVHVSGHPRRSELRKMYEWVRPQIGVPVHGEAAHLVAQGSLMSTSGIGQVAQVRD
ECCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCEECCCCCCCEEEECC
GDMLRLAPGPATIIDQVPFGRIYKDGNLIGTDQAMGIRDRRKLSFAGHVAVNVVLDDKYE
CCEEEECCCCCHHHCCCCCCEEEECCCEEECCCCCCCCCCCEEEEECEEEEEEEECCCEE
LAGDPDLVAIGVAEADASGETLEDLMIDAAVGAVDSIPRQRRKDLDLVQEAVRRAVRGAA
CCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NEAWGKKPLVTVFVTR
HHHCCCCCEEEEEEEC
>Mature Secondary Structure 
AKAENAELVFVPLGGVGEIGMNFALYGYGPPSAREWIVIDVGVTFPDAAHPGVDLILPD
CCCCCCCEEEEECCCCCCCCCCEEEEECCCCCCCEEEEEEECCCCCCCCCCCCEEEECC
TRFIEENLANLRGIIITHAHEDHYGALLDTWPKLKAPVWMTPFSAGLLEAKRQGEQGAPK
HHHHHHHHHCCCEEEEEECCCCCCCHHHHCCCCCCCCEEECCCHHHHHHHHHCCCCCCCC
IPLTIYRAGEKFTVGPFEIEAIPVAHSIPEPMSLAITTPAGTVIHTGDWKIDPEPTIGPK
CCEEEEECCCEEECCCEEEEEEECCCCCCCCCEEEEECCCCCEEECCCEEECCCCCCCCC
TDEARFRAYGDKGVLALICDSTNALREGESPSEVAVGEGLKGVIQSAVGRVAVTTFSSNV
CCCCCEEEECCCCEEEEEECCCHHHHCCCCCCCHHHCCCHHHHHHHHHCEEEEEEECCCC
GRIVSIAKAARDAGRQCLVLGRSLKRVIDVADELGYMDGLPEFIAEEDFGFIPRENLVII
HHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCEEEE
CTGSQGEPLAALAKLSRDEMKSVSLTAGDTVVFSSRTIPGNEKAILEIKNRLIDLGIKII
EECCCCCHHHHHHHHCHHHHHEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHCCEEEE
EDGDALVHVSGHPRRSELRKMYEWVRPQIGVPVHGEAAHLVAQGSLMSTSGIGQVAQVRD
ECCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCEECCCCCCCEEEECC
GDMLRLAPGPATIIDQVPFGRIYKDGNLIGTDQAMGIRDRRKLSFAGHVAVNVVLDDKYE
CCEEEECCCCCHHHCCCCCCEEEECCCEEECCCCCCCCCCCEEEEECEEEEEEEECCCEE
LAGDPDLVAIGVAEADASGETLEDLMIDAAVGAVDSIPRQRRKDLDLVQEAVRRAVRGAA
CCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NEAWGKKPLVTVFVTR
HHHCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12948626 [H]