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The map label for this gene is birA [H]

Identifier: 13471392

GI number: 13471392

Start: 1130933

End: 1131754

Strand: Reverse

Name: birA [H]

Synonym: mll1351

Alternate gene names: 13471392

Gene position: 1131754-1130933 (Counterclockwise)

Preceding gene: 13471393

Following gene: 13471391

Centisome position: 16.09

GC content: 67.03

Gene sequence:

>822_bases
ATGGCATTTCGGCTGGCCCCAACCTCGTTGTCGGAAGGGTTCCGGCTCGAGGCCCATGACAGCGTCGGCTCCACCAACAC
GGTGGCGCTGGACCACGCAAGGGCAGGCGACCCGGGCAGGCTGTGGGTCGTTTCCAAGAAGCAGGAAAGCGGGCGTGGCC
GGCGCGGCCGCGCCTGGGTGTCGCCTGAAGGCAATCTCGCGGCGACCCTGCTCGTCATCACCGGTGGTGAACTGCGCCTC
GCCGCGACGCTGGGTTTCGTCGCCGGCCTGTCGCTTGCCGACGCACTCGACGCCGTGGTGCCGAAAGGCCGCGTCGCCGT
CGGGCTTGATGGCGCGAGCCAGGGACAAAACCGTTTCGAGCTGAAATGGCCGAACGATGTGCTTGCCTCGGGCGCGAAGC
TCGCCGGCATCCTGCTGGAGTCGGCGATACTGGAGGGTGGCCGCTTTGCGGTGGCGGTCGGCATCGGCGTCAATGTGGTG
GCGCACCCTAAGGATTTGCCTTATCCCGCGACATCGCTGCAGGCTCTGGGCGCGACATGCGATGCCGAGACGCTGTTCCT
GGCGCTGTCCGATGCCTGGAGCGAGAATGCCCGTCTGTGGGATGAAGGCCGCGGCCTCTCTGCCGTCAGGCGGCGCTGGC
TGGCGCGCGCGGCGGGACTTGGCGGCGAGGTTGCCGTCAGAATTGACGGTAATGTGGTGCGTGGGGTGTTCGAGACCATT
GACGAGGACTGCCGTTTCGTGATCCGCGACGATGAGGGGACTGTCCTGACGATCGCGGCCGGCGACGTGCATTTCGGCGC
AGTGGCGTCCGCTCGGGTATAA

Upstream 100 bases:

>100_bases
GTGCTCGGCGTCTGCGGCGCCTTCGTGCTGTTCTATGTGCTGATCGGCGGACCGATCGGCACCTATGCCGAAGCCGCCGC
CAAGACATTTTTCTGACGGG

Downstream 100 bases:

>100_bases
TGGGCTGGCCTGAGGGCCAGGAAGGGAAAAATCATGGCGAAAGCGGAAAACGCCGAACTCGTCTTCGTGCCGCTCGGCGG
CGTCGGCGAGATCGGCATGA

Product: biotin--protein ligase

Products: NA

Alternate protein names: Biotin--protein ligase [H]

Number of amino acids: Translated: 273; Mature: 272

Protein sequence:

>273_residues
MAFRLAPTSLSEGFRLEAHDSVGSTNTVALDHARAGDPGRLWVVSKKQESGRGRRGRAWVSPEGNLAATLLVITGGELRL
AATLGFVAGLSLADALDAVVPKGRVAVGLDGASQGQNRFELKWPNDVLASGAKLAGILLESAILEGGRFAVAVGIGVNVV
AHPKDLPYPATSLQALGATCDAETLFLALSDAWSENARLWDEGRGLSAVRRRWLARAAGLGGEVAVRIDGNVVRGVFETI
DEDCRFVIRDDEGTVLTIAAGDVHFGAVASARV

Sequences:

>Translated_273_residues
MAFRLAPTSLSEGFRLEAHDSVGSTNTVALDHARAGDPGRLWVVSKKQESGRGRRGRAWVSPEGNLAATLLVITGGELRL
AATLGFVAGLSLADALDAVVPKGRVAVGLDGASQGQNRFELKWPNDVLASGAKLAGILLESAILEGGRFAVAVGIGVNVV
AHPKDLPYPATSLQALGATCDAETLFLALSDAWSENARLWDEGRGLSAVRRRWLARAAGLGGEVAVRIDGNVVRGVFETI
DEDCRFVIRDDEGTVLTIAAGDVHFGAVASARV
>Mature_272_residues
AFRLAPTSLSEGFRLEAHDSVGSTNTVALDHARAGDPGRLWVVSKKQESGRGRRGRAWVSPEGNLAATLLVITGGELRLA
ATLGFVAGLSLADALDAVVPKGRVAVGLDGASQGQNRFELKWPNDVLASGAKLAGILLESAILEGGRFAVAVGIGVNVVA
HPKDLPYPATSLQALGATCDAETLFLALSDAWSENARLWDEGRGLSAVRRRWLARAAGLGGEVAVRIDGNVVRGVFETID
EDCRFVIRDDEGTVLTIAAGDVHFGAVASARV

Specific function: Activates biotin to form biotinyl-5'-adenylate and transfers the biotin moiety to biotin-accepting proteins [H]

COG id: COG0340

COG function: function code H; Biotin-(acetyl-CoA carboxylase) ligase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the biotin--protein ligase family [H]

Homologues:

Organism=Escherichia coli, GI1790408, Length=237, Percent_Identity=26.1603375527426, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004408
- InterPro:   IPR003142
- InterPro:   IPR004143 [H]

Pfam domain/function: PF02237 BPL_C; PF03099 BPL_LipA_LipB [H]

EC number: =6.3.4.15 [H]

Molecular weight: Translated: 28558; Mature: 28426

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFRLAPTSLSEGFRLEAHDSVGSTNTVALDHARAGDPGRLWVVSKKQESGRGRRGRAWV
CEEEECCCCCCCCCEEEECCCCCCCCEEEEECCCCCCCCEEEEEECCCCCCCCCCCCEEE
SPEGNLAATLLVITGGELRLAATLGFVAGLSLADALDAVVPKGRVAVGLDGASQGQNRFE
CCCCCEEEEEEEEECCCEEEEEHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEE
LKWPNDVLASGAKLAGILLESAILEGGRFAVAVGIGVNVVAHPKDLPYPATSLQALGATC
EECCHHHHHCCHHHHHHHHHHHHHCCCCEEEEEECCEEEEECCCCCCCCCHHHHHHCCCC
DAETLFLALSDAWSENARLWDEGRGLSAVRRRWLARAAGLGGEVAVRIDGNVVRGVFETI
CCCEEEEEEECCCCCCCEEECCCCCHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHH
DEDCRFVIRDDEGTVLTIAAGDVHFGAVASARV
CCCCEEEEECCCCCEEEEEECCEEECCEEECCC
>Mature Secondary Structure 
AFRLAPTSLSEGFRLEAHDSVGSTNTVALDHARAGDPGRLWVVSKKQESGRGRRGRAWV
EEEECCCCCCCCCEEEECCCCCCCCEEEEECCCCCCCCEEEEEECCCCCCCCCCCCEEE
SPEGNLAATLLVITGGELRLAATLGFVAGLSLADALDAVVPKGRVAVGLDGASQGQNRFE
CCCCCEEEEEEEEECCCEEEEEHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEE
LKWPNDVLASGAKLAGILLESAILEGGRFAVAVGIGVNVVAHPKDLPYPATSLQALGATC
EECCHHHHHCCHHHHHHHHHHHHHCCCCEEEEEECCEEEEECCCCCCCCCHHHHHHCCCC
DAETLFLALSDAWSENARLWDEGRGLSAVRRRWLARAAGLGGEVAVRIDGNVVRGVFETI
CCCEEEEEEECCCCCCCEEECCCCCHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHH
DEDCRFVIRDDEGTVLTIAAGDVHFGAVASARV
CCCCEEEEECCCCCEEEEEECCEEECCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8422400 [H]