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The map label for this gene is fabF [H]

Identifier: 13471256

GI number: 13471256

Start: 987706

End: 988896

Strand: Direct

Name: fabF [H]

Synonym: mlr1176

Alternate gene names: 13471256

Gene position: 987706-988896 (Clockwise)

Preceding gene: 161621453

Following gene: 13471257

Centisome position: 14.04

GC content: 66.58

Gene sequence:

>1191_bases
ATGAGTAGCCCCTGCGACGTCGTCATCACTGGTATCGGCCTTGTCTCCTCGCTGGGAGAAGGCCCTGACGCCCACTGGCA
GAAACTCGCGCAACCGGGCCTGCAGCCGGTGCTCGAAGCCGCGCGCTTCGCGCCCTATACCGTTCATCCGCTGCCGGAGA
TCGACTGGAACCTGCAGATCGCCAAGCGTGGCGATCAGCGGCAGATGGAGACGTGGCAACGGCTTGGCACCTATGCCGCC
GGCCTGGCGCTCGATGACGCCGGCATCAAGGGCAATGACGAGCTTTGCACGACCATGGACATGGTGGTGGCCGCCGGCGG
CGGCGAGCGCGACGAGGCGGTCGACGCCGCTATCCTCGCCGCCTCGGAAAGCCGCAACGACCGCGACGTGCTGCTCAACG
AGAAGCTGACCACCGAATTGCGGCCGACCTTGTTCCTCGCGCAGCTTTCCAACCTTCTCGCCGGCAACATCTCCATCGTC
CATAAGGTGACGGGCTCCTCGCGCACCTTCATGGGCGAGGAAGGCGCAGGTGTTTCCGCCGTCGAGACGGCCGCGGCGCG
CATCCGCTCGGGCCAGTCGACGCACGTGCTGGTCGGCGGCGCTTTCCAGACCGAACATTCCGATATGCTGCTCGGTTACG
AGCTCGCCGGCTATCTGCATCGCGGCCCCTGGAAGCCTGTCTGGCAACGGCAGGGCGCCGAGGGCGGCGGCGTGGTCTCG
GGCTCCGGCGGCGCCTTCCTGGTGCTGGAACAGCGCGAACACGCGGAAAGCCGTGGGCGCAAAATCTATGCCGAGCTCGG
ACCGGTCGTCTCAGGGCGGGCCAGGCGGTCGCGCGGAGAACTCGACGCCGAGATCGCCGGATTGCTCGGCGCGGCGGCCC
TGCCGAACGGCAAGCTGCTGGCGCTTTCGGGTGCCTCGGGCGCGCATGCGGCAACGTCAGCCGAGAAAACAGCGCTCGAT
GCCAATCCGGCAATATCAGCACGCGGCTTCTCGACACTGACCGGGCACATGAAGGAAGCGCAGTTTCCGTTCGCCGTGGC
GCTTGCCGCACTCGCCGTCGACCGCAAGGCCGCCTACCCCGTCTTCGATGCCGCAGCCGAAAAGCCGTTTGAGGGCATTC
CCGCAAGCGTCCTTGCAACGGCGATCGGCTATCACCAATTCGAGGGCATGGCGCTGGTCAAGTCGACGTAA

Upstream 100 bases:

>100_bases
CTGTGCGCCAAGATCGACGCGCTGGTCGCCGCCAAGACCGCCTGACGTAGTTGAGCGCGCGACCTTGACGCGCTTTGCCG
CCTGACCCACAAAGCCGCCC

Downstream 100 bases:

>100_bases
GGCGGCGCCCGCCATGTTGTTAGAGACAAACCGCCCGAGGGCTTCCCGATGACCAATTTCAGAGATCACATGGGCAGGCC
CGTCGTCGCCGTCACCGGTA

Product: 3-oxoacyl-(acyl carrier protein) synthase II

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MSSPCDVVITGIGLVSSLGEGPDAHWQKLAQPGLQPVLEAARFAPYTVHPLPEIDWNLQIAKRGDQRQMETWQRLGTYAA
GLALDDAGIKGNDELCTTMDMVVAAGGGERDEAVDAAILAASESRNDRDVLLNEKLTTELRPTLFLAQLSNLLAGNISIV
HKVTGSSRTFMGEEGAGVSAVETAAARIRSGQSTHVLVGGAFQTEHSDMLLGYELAGYLHRGPWKPVWQRQGAEGGGVVS
GSGGAFLVLEQREHAESRGRKIYAELGPVVSGRARRSRGELDAEIAGLLGAAALPNGKLLALSGASGAHAATSAEKTALD
ANPAISARGFSTLTGHMKEAQFPFAVALAALAVDRKAAYPVFDAAAEKPFEGIPASVLATAIGYHQFEGMALVKST

Sequences:

>Translated_396_residues
MSSPCDVVITGIGLVSSLGEGPDAHWQKLAQPGLQPVLEAARFAPYTVHPLPEIDWNLQIAKRGDQRQMETWQRLGTYAA
GLALDDAGIKGNDELCTTMDMVVAAGGGERDEAVDAAILAASESRNDRDVLLNEKLTTELRPTLFLAQLSNLLAGNISIV
HKVTGSSRTFMGEEGAGVSAVETAAARIRSGQSTHVLVGGAFQTEHSDMLLGYELAGYLHRGPWKPVWQRQGAEGGGVVS
GSGGAFLVLEQREHAESRGRKIYAELGPVVSGRARRSRGELDAEIAGLLGAAALPNGKLLALSGASGAHAATSAEKTALD
ANPAISARGFSTLTGHMKEAQFPFAVALAALAVDRKAAYPVFDAAAEKPFEGIPASVLATAIGYHQFEGMALVKST
>Mature_395_residues
SSPCDVVITGIGLVSSLGEGPDAHWQKLAQPGLQPVLEAARFAPYTVHPLPEIDWNLQIAKRGDQRQMETWQRLGTYAAG
LALDDAGIKGNDELCTTMDMVVAAGGGERDEAVDAAILAASESRNDRDVLLNEKLTTELRPTLFLAQLSNLLAGNISIVH
KVTGSSRTFMGEEGAGVSAVETAAARIRSGQSTHVLVGGAFQTEHSDMLLGYELAGYLHRGPWKPVWQRQGAEGGGVVSG
SGGAFLVLEQREHAESRGRKIYAELGPVVSGRARRSRGELDAEIAGLLGAAALPNGKLLALSGASGAHAATSAEKTALDA
NPAISARGFSTLTGHMKEAQFPFAVALAALAVDRKAAYPVFDAAAEKPFEGIPASVLATAIGYHQFEGMALVKST

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Has a preference for short chain acid substrates and may function to supply the octanoic substrates for lipoic acid biosynthes

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Escherichia coli, GI1787337, Length=268, Percent_Identity=26.4925373134328, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 41472; Mature: 41341

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSPCDVVITGIGLVSSLGEGPDAHWQKLAQPGLQPVLEAARFAPYTVHPLPEIDWNLQI
CCCCCCEEEEHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHCCCEEECCCCCCCCCEEE
AKRGDQRQMETWQRLGTYAAGLALDDAGIKGNDELCTTMDMVVAAGGGERDEAVDAAILA
ECCCCHHHHHHHHHHHHHHHCEEEECCCCCCCCHHHHHHHHHEECCCCCCHHHHHHHHEE
ASESRNDRDVLLNEKLTTELRPTLFLAQLSNLLAGNISIVHKVTGSSRTFMGEEGAGVSA
ECCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCEECCCCCCCCHH
VETAAARIRSGQSTHVLVGGAFQTEHSDMLLGYELAGYLHRGPWKPVWQRQGAEGGGVVS
HHHHHHHHHCCCCCEEEEECEEECCCCCEEEHHHHHHHHHCCCCCHHHHHCCCCCCCEEE
GSGGAFLVLEQREHAESRGRKIYAELGPVVSGRARRSRGELDAEIAGLLGAAALPNGKLL
CCCCEEEEEECHHHHHHCCCEEEEHHCCCCCCCHHHCCCCCHHHHHHHHHHHCCCCCCEE
ALSGASGAHAATSAEKTALDANPAISARGFSTLTGHMKEAQFPFAVALAALAVDRKAAYP
EEECCCCCCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCC
VFDAAAEKPFEGIPASVLATAIGYHQFEGMALVKST
HHHHHHCCCCCCCCHHHHHHHHHHHHHCCEEEEECC
>Mature Secondary Structure 
SSPCDVVITGIGLVSSLGEGPDAHWQKLAQPGLQPVLEAARFAPYTVHPLPEIDWNLQI
CCCCCEEEEHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHCCCEEECCCCCCCCCEEE
AKRGDQRQMETWQRLGTYAAGLALDDAGIKGNDELCTTMDMVVAAGGGERDEAVDAAILA
ECCCCHHHHHHHHHHHHHHHCEEEECCCCCCCCHHHHHHHHHEECCCCCCHHHHHHHHEE
ASESRNDRDVLLNEKLTTELRPTLFLAQLSNLLAGNISIVHKVTGSSRTFMGEEGAGVSA
ECCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCEECCCCCCCCHH
VETAAARIRSGQSTHVLVGGAFQTEHSDMLLGYELAGYLHRGPWKPVWQRQGAEGGGVVS
HHHHHHHHHCCCCCEEEEECEEECCCCCEEEHHHHHHHHHCCCCCHHHHHCCCCCCCEEE
GSGGAFLVLEQREHAESRGRKIYAELGPVVSGRARRSRGELDAEIAGLLGAAALPNGKLL
CCCCEEEEEECHHHHHHCCCEEEEHHCCCCCCCHHHCCCCCHHHHHHHHHHHCCCCCCEE
ALSGASGAHAATSAEKTALDANPAISARGFSTLTGHMKEAQFPFAVALAALAVDRKAAYP
EEECCCCCCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCC
VFDAAAEKPFEGIPASVLATAIGYHQFEGMALVKST
HHHHHHCCCCCCCCHHHHHHHHHHHHHCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550484 [H]