The gene/protein map for NC_002678 is currently unavailable.
Definition Mesorhizobium loti MAFF303099 chromosome, complete genome.
Accession NC_002678
Length 7,036,071

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The map label for this gene is hmuV

Identifier: 13471233

GI number: 13471233

Start: 962094

End: 962885

Strand: Reverse

Name: hmuV

Synonym: mll1149

Alternate gene names: 13471233

Gene position: 962885-962094 (Counterclockwise)

Preceding gene: 13471234

Following gene: 13471231

Centisome position: 13.68

GC content: 64.77

Gene sequence:

>792_bases
ATGATCGAGGCAAGGGATGTTTCCGTCGATATCGCCGGCAAGCGCATCGTCGGCGGTGTCGATTTCGACGCCCGGCCCGG
CGAAGTCGCGGCCATCGTCGGTCCTAACGGTTCGGGCAAGACGACCTTCCTGAAGGCTTTGTCGGGCGAGTTCGCCTACA
CCGGGCGCATCGCGCTCAACGGCCATAACCTTTCGTCGATGAGGCCGGCCGAGATGGCGGTGCATCGCGCGGTGCTGCCG
CAGGCGACGACGCTGTCCTTCCCGTTCACAGTGCGCGAGGTGGTCAAGCTCGGCCTTGTCGGCGGGCGCTCGGGCGCCTT
GCCGGGCGAGGATGCGCGGCTGCCGGAGCGGGCGCTGGCGCGTGTCGACCTCGACGGTTTTGCAGGACGTTTCTATCAGG
AGCTTTCGGGCGGCGAGCAGCAGCGCGTCCAGCTTGCGCGCGTGCTGTGCCAGGTCTGGGCGCCGGTGCTCGACGGCAAG
CCGCGCTACCTGTTCCTCGACGAGCCGGTTTCCAGCCTCGACATCAAGCACCAGCTGATCATCATGAATATCGCCCGGGA
TTTCGCCAAAAGGGGCGGGGGTGTGGTCGCCATCCTGCACGACCTCAATCTGACTTCCATGTATGCCGACCGGATTTTCG
TCATGCATCGCGGCCGGCTCGCGGCCACCGGTTCGCCACAGGACGTGCTGAGCGATGATCTGATCGAAAAAGTGTTTGAT
TGCCGGCTCAGGGTCGGCGTGCTGCCGGCCGGCAACATGCCGTTCGTGTTGCCGCAATCGTCGGTCTATTGA

Upstream 100 bases:

>100_bases
CCGATCGGCATCGTCACCGCGATCGCGGGCGCGCCGTTCTTCCTGTGGATCCTGCTGCGCAAGCGCGGCGTGGTCGATCT
CTGAGACCTATGAGGCGTTG

Downstream 100 bases:

>100_bases
GGCCGGCCTGCGAATGGCAGGTTTCCTGCGCTTCCGGTACTCACGTACCCGAAAGTACGCTCCGTTCCGGTTCTCGGAAC
CCGCCATTCTCGACTCGGCC

Product: hemin importer ATP-binding subunit

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MIEARDVSVDIAGKRIVGGVDFDARPGEVAAIVGPNGSGKTTFLKALSGEFAYTGRIALNGHNLSSMRPAEMAVHRAVLP
QATTLSFPFTVREVVKLGLVGGRSGALPGEDARLPERALARVDLDGFAGRFYQELSGGEQQRVQLARVLCQVWAPVLDGK
PRYLFLDEPVSSLDIKHQLIIMNIARDFAKRGGGVVAILHDLNLTSMYADRIFVMHRGRLAATGSPQDVLSDDLIEKVFD
CRLRVGVLPAGNMPFVLPQSSVY

Sequences:

>Translated_263_residues
MIEARDVSVDIAGKRIVGGVDFDARPGEVAAIVGPNGSGKTTFLKALSGEFAYTGRIALNGHNLSSMRPAEMAVHRAVLP
QATTLSFPFTVREVVKLGLVGGRSGALPGEDARLPERALARVDLDGFAGRFYQELSGGEQQRVQLARVLCQVWAPVLDGK
PRYLFLDEPVSSLDIKHQLIIMNIARDFAKRGGGVVAILHDLNLTSMYADRIFVMHRGRLAATGSPQDVLSDDLIEKVFD
CRLRVGVLPAGNMPFVLPQSSVY
>Mature_263_residues
MIEARDVSVDIAGKRIVGGVDFDARPGEVAAIVGPNGSGKTTFLKALSGEFAYTGRIALNGHNLSSMRPAEMAVHRAVLP
QATTLSFPFTVREVVKLGLVGGRSGALPGEDARLPERALARVDLDGFAGRFYQELSGGEQQRVQLARVLCQVWAPVLDGK
PRYLFLDEPVSSLDIKHQLIIMNIARDFAKRGGGVVAILHDLNLTSMYADRIFVMHRGRLAATGSPQDVLSDDLIEKVFD
CRLRVGVLPAGNMPFVLPQSSVY

Specific function: Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system

COG id: COG4559

COG function: function code P; ABC-type hemin transport system, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain

Homologues:

Organism=Homo sapiens, GI45446740, Length=229, Percent_Identity=30.1310043668122, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI47078218, Length=229, Percent_Identity=30.1310043668122, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI9955963, Length=242, Percent_Identity=30.1652892561983, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI27477115, Length=230, Percent_Identity=26.9565217391304, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI11967969, Length=229, Percent_Identity=27.9475982532751, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI150417984, Length=205, Percent_Identity=27.3170731707317, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI255708477, Length=232, Percent_Identity=26.7241379310345, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI148612844, Length=232, Percent_Identity=26.7241379310345, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI42741659, Length=228, Percent_Identity=25.8771929824561, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI171184400, Length=214, Percent_Identity=29.4392523364486, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI42490749, Length=236, Percent_Identity=28.3898305084746, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI21536376, Length=203, Percent_Identity=27.5862068965517, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI25914749, Length=211, Percent_Identity=34.5971563981043, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI27436953, Length=231, Percent_Identity=26.8398268398268, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI9961252, Length=228, Percent_Identity=25, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI4505771, Length=228, Percent_Identity=25, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI21536378, Length=231, Percent_Identity=25.1082251082251, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1790739, Length=259, Percent_Identity=31.2741312741313, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1786345, Length=254, Percent_Identity=31.496062992126, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1786803, Length=240, Percent_Identity=30, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1788002, Length=235, Percent_Identity=32.7659574468085, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1787029, Length=235, Percent_Identity=30.2127659574468, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1787370, Length=225, Percent_Identity=33.7777777777778, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1788225, Length=244, Percent_Identity=30.7377049180328, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI87081709, Length=232, Percent_Identity=30.1724137931034, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87081791, Length=240, Percent_Identity=32.0833333333333, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1790544, Length=228, Percent_Identity=31.140350877193, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1789672, Length=235, Percent_Identity=27.2340425531915, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1789873, Length=214, Percent_Identity=32.2429906542056, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1789991, Length=241, Percent_Identity=27.8008298755187, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1788165, Length=233, Percent_Identity=27.0386266094421, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787712, Length=231, Percent_Identity=30.3030303030303, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1789593, Length=240, Percent_Identity=23.75, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1787792, Length=243, Percent_Identity=27.9835390946502, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1786872, Length=212, Percent_Identity=28.3018867924528, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1787500, Length=231, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788761, Length=235, Percent_Identity=27.6595744680851, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI87081834, Length=213, Percent_Identity=32.3943661971831, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788210, Length=239, Percent_Identity=28.8702928870293, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1789864, Length=234, Percent_Identity=27.7777777777778, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1786563, Length=223, Percent_Identity=26.9058295964126, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790467, Length=214, Percent_Identity=28.9719626168224, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI48994883, Length=235, Percent_Identity=28.0851063829787, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI87082267, Length=218, Percent_Identity=27.9816513761468, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1789032, Length=224, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI48995001, Length=218, Percent_Identity=28.8990825688073, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1789891, Length=216, Percent_Identity=30.0925925925926, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1786319, Length=222, Percent_Identity=26.5765765765766, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI87081782, Length=233, Percent_Identity=27.8969957081545, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI48994943, Length=235, Percent_Identity=28.0851063829787, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1786253, Length=210, Percent_Identity=29.5238095238095, Blast_Score=70, Evalue=9e-14,
Organism=Escherichia coli, GI145693107, Length=228, Percent_Identity=29.8245614035088, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788897, Length=211, Percent_Identity=29.3838862559242, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788644, Length=235, Percent_Identity=29.3617021276596, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789962, Length=229, Percent_Identity=27.0742358078603, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789963, Length=232, Percent_Identity=27.5862068965517, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1786703, Length=215, Percent_Identity=32.093023255814, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788053, Length=183, Percent_Identity=30.6010928961749, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1790190, Length=254, Percent_Identity=24.0157480314961, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1787164, Length=216, Percent_Identity=30.5555555555556, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788450, Length=252, Percent_Identity=25, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1787112, Length=220, Percent_Identity=28.6363636363636, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1788506, Length=216, Percent_Identity=25, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787972, Length=238, Percent_Identity=27.7310924369748, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787759, Length=231, Percent_Identity=25.5411255411255, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI193209708, Length=236, Percent_Identity=29.6610169491525, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17541710, Length=231, Percent_Identity=30.7359307359307, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71996809, Length=229, Percent_Identity=28.82096069869, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI193211017, Length=229, Percent_Identity=28.3842794759825, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI193211015, Length=229, Percent_Identity=28.3842794759825, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI25146777, Length=226, Percent_Identity=29.2035398230088, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17565938, Length=226, Percent_Identity=28.3185840707965, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17569145, Length=226, Percent_Identity=29.646017699115, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17558664, Length=229, Percent_Identity=27.0742358078603, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71992285, Length=229, Percent_Identity=27.5109170305677, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI212646699, Length=238, Percent_Identity=28.1512605042017, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193208177, Length=221, Percent_Identity=28.0542986425339, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI115533608, Length=218, Percent_Identity=26.605504587156, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17543740, Length=224, Percent_Identity=27.2321428571429, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI71983523, Length=218, Percent_Identity=30.2752293577982, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71983510, Length=218, Percent_Identity=30.2752293577982, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71983516, Length=218, Percent_Identity=30.2752293577982, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17539902, Length=230, Percent_Identity=29.5652173913043, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17569143, Length=226, Percent_Identity=28.3185840707965, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71984940, Length=236, Percent_Identity=27.9661016949153, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17510237, Length=216, Percent_Identity=28.7037037037037, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71992290, Length=241, Percent_Identity=27.3858921161826, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI193202349, Length=227, Percent_Identity=26.8722466960352, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17567269, Length=221, Percent_Identity=28.9592760180996, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17567265, Length=223, Percent_Identity=28.2511210762332, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI115534520, Length=247, Percent_Identity=25.5060728744939, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115535101, Length=222, Percent_Identity=27.9279279279279, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322640, Length=231, Percent_Identity=29.4372294372294, Blast_Score=80, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6323959, Length=227, Percent_Identity=31.7180616740088, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21357907, Length=246, Percent_Identity=31.7073170731707, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI23397593, Length=220, Percent_Identity=30.9090909090909, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI85816269, Length=226, Percent_Identity=27.8761061946903, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24580553, Length=226, Percent_Identity=27.8761061946903, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI85724864, Length=226, Percent_Identity=27.8761061946903, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24580555, Length=226, Percent_Identity=27.8761061946903, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24666092, Length=237, Percent_Identity=25.7383966244726, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HMUV_RHILO (Q98L75)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_102802.1
- HSSP:   Q5SH92
- ProteinModelPortal:   Q98L75
- GeneID:   1225465
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mll1149
- NMPDR:   fig|266835.1.peg.907
- HOGENOM:   HBG758042
- OMA:   AAMDISH
- ProtClustDB:   PRK13548
- HAMAP:   MF_01718
- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR015863
- InterPro:   IPR003593
- SMART:   SM00382

Pfam domain/function: PF00005 ABC_tran

EC number: NA

Molecular weight: Translated: 28452; Mature: 28452

Theoretical pI: Translated: 8.70; Mature: 8.70

Prosite motif: PS00211 ABC_TRANSPORTER_1; PS50893 ABC_TRANSPORTER_2; PS51261 HMUV

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MIEARDVSVDIAGKRIVGGVDFDARPGEVAAIVGPNGSGKTTFLKALSGEFAYTGRIALN
CCCCCEEEEEECCCEEEECCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCEEEEEEEEEC
GHNLSSMRPAEMAVHRAVLPQATTLSFPFTVREVVKLGLVGGRSGALPGEDARLPERALA
CCCCCCCCHHHHHHHHHHCCCCEEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHH
RVDLDGFAGRFYQELSGGEQQRVQLARVLCQVWAPVLDGKPRYLFLDEPVSSLDIKHQLI
HCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHCCCCCEEE
IMNIARDFAKRGGGVVAILHDLNLTSMYADRIFVMHRGRLAATGSPQDVLSDDLIEKVFD
HHHHHHHHHHCCCCEEEEEECCCHHHHHHHEEEEEECCEEEECCCCHHHHHHHHHHHHHH
CRLRVGVLPAGNMPFVLPQSSVY
HHEEEEEECCCCCCEECCCCCCC
>Mature Secondary Structure
MIEARDVSVDIAGKRIVGGVDFDARPGEVAAIVGPNGSGKTTFLKALSGEFAYTGRIALN
CCCCCEEEEEECCCEEEECCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCEEEEEEEEEC
GHNLSSMRPAEMAVHRAVLPQATTLSFPFTVREVVKLGLVGGRSGALPGEDARLPERALA
CCCCCCCCHHHHHHHHHHCCCCEEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHH
RVDLDGFAGRFYQELSGGEQQRVQLARVLCQVWAPVLDGKPRYLFLDEPVSSLDIKHQLI
HCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHCCCCCEEE
IMNIARDFAKRGGGVVAILHDLNLTSMYADRIFVMHRGRLAATGSPQDVLSDDLIEKVFD
HHHHHHHHHHCCCCEEEEEECCCHHHHHHHEEEEEECCEEEECCCCHHHHHHHHHHHHHH
CRLRVGVLPAGNMPFVLPQSSVY
HHEEEEEECCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11214968