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The map label for this gene is cobT [H]

Identifier: 13470770

GI number: 13470770

Start: 413279

End: 414277

Strand: Reverse

Name: cobT [H]

Synonym: mll0563

Alternate gene names: 13470770

Gene position: 414277-413279 (Counterclockwise)

Preceding gene: 13470773

Following gene: 13470768

Centisome position: 5.89

GC content: 67.97

Gene sequence:

>999_bases
ATGACCAGCGCTCTGCCTTTCGACGATTTTCGCAACCTGCTCGACAATATGCCGGCAGCCGATCTCAAAGCCGAAGCGCG
CGTGCGCGCGCTGTTTGCCAAGGCCGACAAGCCGGCGCATTCGCTCGGCCGCATCGAGGACATCGCCGCGTGGCTTGCCG
CCTGGAGCGGCCGGTCTCCGCCCGCGGTGACACGGCCGTTGATGGCGGTCTTTGCCGGCAATCACGGCGTGACCCGTCAT
GGCATTTCGCCGCGCCCGGTGGCGGCAACCGCCAACGCGGTCGAGCTTTGCGCGGCAGGCGGTGCGGCGATCAACCAGAT
CTGCATTGCCTATGATCTGGGATTGAAGGTGTTCGATCTTGCCCTGCATATCCCGACCGGCGACATCGCAGAGGATGCCG
CGCTTGACGAGCGCGGATGCGCGGCGACCATGGCCTTCGGCATGGAAGCGATCGCCGGCGGCACCGATCTGCTTTGCCTC
GGCGATCTCGGCGTCGGCAATTCCACCGTCGCCGCCGCCCTGTTTGCCGCGCTGTTCGGAGGCAGGGGTGCCGATTGGGT
TGGCCCGGGATCCGGCGCCGACGCGGCAATGCAGGCGCGCAAGGCGGATGTGGTCGATGCGGCGCTGGCCTTTCACCACG
GCCATCTCGACGACCCGTTGGAAGTGCTGCGCCGGGTCGGCGGCCGCGAGTTCGCCGCGATAGCCGGCGCCATCCTCGCC
GCGCGGATGCAGAAGATTCCCGTGCTGCTCGACGGCTTTGCCACAACGGCTGCCGCGGCGGTGCTTTATGCCGCGAATCC
TGGGGCCCTGGATCATTGTCTTCTCGCCAGCCTGTCGCCGGAGCCCGCGCATACCAGGGCCGCCGAGCTGCTTGGCTTCC
GTCCGCTGCTCGACCTCGGCATAGGCCATGGCGAAGGGGCAGGGGCTGCACTTGGCGCGGGCCTGGTCAAGGCGGCGGCG
CTAACCAGTTCAGGCATGGCGGCGGCGGTTCGGATCTAG

Upstream 100 bases:

>100_bases
GCCATCTTTGCGGCAATCAAGGCGGATGTTTGGGAGAGGTTGTGCCGATCACGCAACGCAGCTATGCCGCTCACCAAATC
CAGGAATGATTGCTCACGAC

Downstream 100 bases:

>100_bases
GTGCAAGGCACATCGGACGCTGACGAGGTCCGTTACCGCCGTCGCGCCGCCACCGCCGCGGTCGGCAACGCCGGCAGTTC
TTCCATCACCCGGCTCAGGG

Product: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MTSALPFDDFRNLLDNMPAADLKAEARVRALFAKADKPAHSLGRIEDIAAWLAAWSGRSPPAVTRPLMAVFAGNHGVTRH
GISPRPVAATANAVELCAAGGAAINQICIAYDLGLKVFDLALHIPTGDIAEDAALDERGCAATMAFGMEAIAGGTDLLCL
GDLGVGNSTVAAALFAALFGGRGADWVGPGSGADAAMQARKADVVDAALAFHHGHLDDPLEVLRRVGGREFAAIAGAILA
ARMQKIPVLLDGFATTAAAAVLYAANPGALDHCLLASLSPEPAHTRAAELLGFRPLLDLGIGHGEGAGAALGAGLVKAAA
LTSSGMAAAVRI

Sequences:

>Translated_332_residues
MTSALPFDDFRNLLDNMPAADLKAEARVRALFAKADKPAHSLGRIEDIAAWLAAWSGRSPPAVTRPLMAVFAGNHGVTRH
GISPRPVAATANAVELCAAGGAAINQICIAYDLGLKVFDLALHIPTGDIAEDAALDERGCAATMAFGMEAIAGGTDLLCL
GDLGVGNSTVAAALFAALFGGRGADWVGPGSGADAAMQARKADVVDAALAFHHGHLDDPLEVLRRVGGREFAAIAGAILA
ARMQKIPVLLDGFATTAAAAVLYAANPGALDHCLLASLSPEPAHTRAAELLGFRPLLDLGIGHGEGAGAALGAGLVKAAA
LTSSGMAAAVRI
>Mature_331_residues
TSALPFDDFRNLLDNMPAADLKAEARVRALFAKADKPAHSLGRIEDIAAWLAAWSGRSPPAVTRPLMAVFAGNHGVTRHG
ISPRPVAATANAVELCAAGGAAINQICIAYDLGLKVFDLALHIPTGDIAEDAALDERGCAATMAFGMEAIAGGTDLLCLG
DLGVGNSTVAAALFAALFGGRGADWVGPGSGADAAMQARKADVVDAALAFHHGHLDDPLEVLRRVGGREFAAIAGAILAA
RMQKIPVLLDGFATTAAAAVLYAANPGALDHCLLASLSPEPAHTRAAELLGFRPLLDLGIGHGEGAGAALGAGLVKAAAL
TSSGMAAAVRI

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=334, Percent_Identity=30.2395209580838, Blast_Score=117, Evalue=9e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 33583; Mature: 33452

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSALPFDDFRNLLDNMPAADLKAEARVRALFAKADKPAHSLGRIEDIAAWLAAWSGRSP
CCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCC
PAVTRPLMAVFAGNHGVTRHGISPRPVAATANAVELCAAGGAAINQICIAYDLGLKVFDL
CHHHHHHHHHHCCCCCCEECCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCEEEEE
ALHIPTGDIAEDAALDERGCAATMAFGMEAIAGGTDLLCLGDLGVGNSTVAAALFAALFG
EEECCCCCCHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHC
GRGADWVGPGSGADAAMQARKADVVDAALAFHHGHLDDPLEVLRRVGGREFAAIAGAILA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHH
ARMQKIPVLLDGFATTAAAAVLYAANPGALDHCLLASLSPEPAHTRAAELLGFRPLLDLG
HHHHHCCHHHHHHHHHHHHHHHEECCCCHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHC
IGHGEGAGAALGAGLVKAAALTSSGMAAAVRI
CCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEC
>Mature Secondary Structure 
TSALPFDDFRNLLDNMPAADLKAEARVRALFAKADKPAHSLGRIEDIAAWLAAWSGRSP
CCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCC
PAVTRPLMAVFAGNHGVTRHGISPRPVAATANAVELCAAGGAAINQICIAYDLGLKVFDL
CHHHHHHHHHHCCCCCCEECCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCEEEEE
ALHIPTGDIAEDAALDERGCAATMAFGMEAIAGGTDLLCLGDLGVGNSTVAAALFAALFG
EEECCCCCCHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHC
GRGADWVGPGSGADAAMQARKADVVDAALAFHHGHLDDPLEVLRRVGGREFAAIAGAILA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHH
ARMQKIPVLLDGFATTAAAAVLYAANPGALDHCLLASLSPEPAHTRAAELLGFRPLLDLG
HHHHHCCHHHHHHHHHHHHHHHEECCCCHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHC
IGHGEGAGAALGAGLVKAAALTSSGMAAAVRI
CCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA