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The map label for this gene is intZ [H]

Identifier: 13470710

GI number: 13470710

Start: 358249

End: 359457

Strand: Reverse

Name: intZ [H]

Synonym: mll0487

Alternate gene names: 13470710

Gene position: 359457-358249 (Counterclockwise)

Preceding gene: 13470712

Following gene: 13470709

Centisome position: 5.11

GC content: 53.1

Gene sequence:

>1209_bases
ATGCTCACTATTCGGGAAATTCAGTCATTGGTTCACAAGGGTGAACCGGGTCAATGGAGCCATACAAAAGCGCTCTATTT
CTTCATCGCGCCGTCCGGTCGTCCCTTTTGGGCAATACGGTACATGCTCAAAGGTCGTCGTCGGCAAATGTCGCTGACGG
ACTCAATCCCGGCGACTGTCCGGGAATTGAAGCAAATCGAATTGCTGTCTGAAACCGAGCGCGAAAAGGTCAGAAAAGGG
ATTGACCCTCTAGCCGAACGGGAGGCGGCGAAGGCTGCCAGTCCAGAACCGGTCCGACAGCTAGTCACGTTCAAATCGGT
CGCCCTGGACTATATCGCGGCGAACCGGGGCGGCTGGAAAAATGCCAAGCATGTTCAACAGTGGGAAAACACGCTCGCGA
CGTACGTATATCCTGTGATCGGCCATCTCGAACCACAGTCGATTACAACAGCCGAAGTCCTGAAAATTCTCCAACCGCTA
TGGGCGACAAAGCGCGAGACGGCATCTCGCGTACGCTCTCGCGTTGAGACAATTATCGGAGCCGCCAAGGCCAAGGGAAT
GTCTGAAAAGCCGGAGATATGGGCAAACCATCACAACCCGGCGCGATGGGCAGACAATCTGGAATTCTGGCTAAACGGCA
AACAGGAAAAGAACCATTTTTCCGCGATGCCGTATCCGGAAATTCCCGCGTTTGCTCAATCAATAGCCGAACGGGAGGAT
TACTCGACCAAGGCGCTTCAATTTCTGATTTTGACAGCGACACGGACGAACGAAACACTTGGCGCTGAATGGTCGGAAAT
AGACACTGAAAAAGCGGTCTGGACGATCCCGGCAAGCCGGATGAAATCCGGCAAGGAACATCGGGTTCCCTTGTCCAGTG
AAGCGTTGAAGCTCGTGGCATCATTGCTCCGCATTGAGGGAAACCCGTATCTTTTCCCCGGAGCAATACGCAACAAATCA
CTCAGCAACATGGCGTTGCTCATGGTCATGCGTGGTTTGAAATTAGGCCACTATGTCCCGCACGGTTTCCGGTCGGCTTT
CCGCGATTGGGCGGCGGAGGAAACCGTATACCCGAACCACATTGTTGAAATGGCGCTGGCCCACACAATCAAAAATAAAG
TTGAAGCCGCTTATCGACGGGGAGATTTGATGGAGAAGCGCCGGCAGTTAATGGAAGATTGGTCGGCATATTTAGCAAGC
GCCCGATAA

Upstream 100 bases:

>100_bases
GCTCACTAACGCTCACAACAGTTCACTGACGCATCACAACGTTTTCTCGCGATTTGGCCACTGGATTTGGCTAGTTCGCC
GTCAGCCGGGATTCAAAATC

Downstream 100 bases:

>100_bases
AACAATTGCCGGCATACTTTTATTTGTGGACACAAAGCGCAACGATTCAAAACGCGTTGACGCTTTGTGTTCCTCTTTGT
ACCTACGAAATCGTCCTTGA

Product: prophage integrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MLTIREIQSLVHKGEPGQWSHTKALYFFIAPSGRPFWAIRYMLKGRRRQMSLTDSIPATVRELKQIELLSETEREKVRKG
IDPLAEREAAKAASPEPVRQLVTFKSVALDYIAANRGGWKNAKHVQQWENTLATYVYPVIGHLEPQSITTAEVLKILQPL
WATKRETASRVRSRVETIIGAAKAKGMSEKPEIWANHHNPARWADNLEFWLNGKQEKNHFSAMPYPEIPAFAQSIAERED
YSTKALQFLILTATRTNETLGAEWSEIDTEKAVWTIPASRMKSGKEHRVPLSSEALKLVASLLRIEGNPYLFPGAIRNKS
LSNMALLMVMRGLKLGHYVPHGFRSAFRDWAAEETVYPNHIVEMALAHTIKNKVEAAYRRGDLMEKRRQLMEDWSAYLAS
AR

Sequences:

>Translated_402_residues
MLTIREIQSLVHKGEPGQWSHTKALYFFIAPSGRPFWAIRYMLKGRRRQMSLTDSIPATVRELKQIELLSETEREKVRKG
IDPLAEREAAKAASPEPVRQLVTFKSVALDYIAANRGGWKNAKHVQQWENTLATYVYPVIGHLEPQSITTAEVLKILQPL
WATKRETASRVRSRVETIIGAAKAKGMSEKPEIWANHHNPARWADNLEFWLNGKQEKNHFSAMPYPEIPAFAQSIAERED
YSTKALQFLILTATRTNETLGAEWSEIDTEKAVWTIPASRMKSGKEHRVPLSSEALKLVASLLRIEGNPYLFPGAIRNKS
LSNMALLMVMRGLKLGHYVPHGFRSAFRDWAAEETVYPNHIVEMALAHTIKNKVEAAYRRGDLMEKRRQLMEDWSAYLAS
AR
>Mature_402_residues
MLTIREIQSLVHKGEPGQWSHTKALYFFIAPSGRPFWAIRYMLKGRRRQMSLTDSIPATVRELKQIELLSETEREKVRKG
IDPLAEREAAKAASPEPVRQLVTFKSVALDYIAANRGGWKNAKHVQQWENTLATYVYPVIGHLEPQSITTAEVLKILQPL
WATKRETASRVRSRVETIIGAAKAKGMSEKPEIWANHHNPARWADNLEFWLNGKQEKNHFSAMPYPEIPAFAQSIAERED
YSTKALQFLILTATRTNETLGAEWSEIDTEKAVWTIPASRMKSGKEHRVPLSSEALKLVASLLRIEGNPYLFPGAIRNKS
LSNMALLMVMRGLKLGHYVPHGFRSAFRDWAAEETVYPNHIVEMALAHTIKNKVEAAYRRGDLMEKRRQLMEDWSAYLAS
AR

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI145693166, Length=386, Percent_Identity=28.4974093264249, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1788690, Length=409, Percent_Identity=26.4058679706601, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1788974, Length=416, Percent_Identity=27.8846153846154, Blast_Score=114, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 45824; Mature: 45824

Theoretical pI: Translated: 10.24; Mature: 10.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTIREIQSLVHKGEPGQWSHTKALYFFIAPSGRPFWAIRYMLKGRRRQMSLTDSIPATV
CCCHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCHHHCCHHHH
RELKQIELLSETEREKVRKGIDPLAEREAAKAASPEPVRQLVTFKSVALDYIAANRGGWK
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
NAKHVQQWENTLATYVYPVIGHLEPQSITTAEVLKILQPLWATKRETASRVRSRVETIIG
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAKAKGMSEKPEIWANHHNPARWADNLEFWLNGKQEKNHFSAMPYPEIPAFAQSIAERED
HHHHCCCCCCCCCCCCCCCCHHHHCCCHHEECCCCCCCCCCCCCCCCCHHHHHHHHHHHC
YSTKALQFLILTATRTNETLGAEWSEIDTEKAVWTIPASRMKSGKEHRVPLSSEALKLVA
CHHHHHHHHEEEECCCCCCCCCCHHHCCCCCEEEECCHHHHCCCCCCCCCCCHHHHHHHH
SLLRIEGNPYLFPGAIRNKSLSNMALLMVMRGLKLGHYVPHGFRSAFRDWAAEETVYPNH
HHHHHCCCCEECCCHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHH
IVEMALAHTIKNKVEAAYRRGDLMEKRRQLMEDWSAYLASAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLTIREIQSLVHKGEPGQWSHTKALYFFIAPSGRPFWAIRYMLKGRRRQMSLTDSIPATV
CCCHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCHHHCCHHHH
RELKQIELLSETEREKVRKGIDPLAEREAAKAASPEPVRQLVTFKSVALDYIAANRGGWK
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
NAKHVQQWENTLATYVYPVIGHLEPQSITTAEVLKILQPLWATKRETASRVRSRVETIIG
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAKAKGMSEKPEIWANHHNPARWADNLEFWLNGKQEKNHFSAMPYPEIPAFAQSIAERED
HHHHCCCCCCCCCCCCCCCCHHHHCCCHHEECCCCCCCCCCCCCCCCCHHHHHHHHHHHC
YSTKALQFLILTATRTNETLGAEWSEIDTEKAVWTIPASRMKSGKEHRVPLSSEALKLVA
CHHHHHHHHEEEECCCCCCCCCCHHHCCCCCEEEECCHHHHCCCCCCCCCCCHHHHHHHH
SLLRIEGNPYLFPGAIRNKSLSNMALLMVMRGLKLGHYVPHGFRSAFRDWAAEETVYPNH
HHHHHCCCCEECCCHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHH
IVEMALAHTIKNKVEAAYRRGDLMEKRRQLMEDWSAYLASAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]