Click here to switch to the map view.

The map label for this gene is namA [H]

Identifier: 13470442

GI number: 13470442

Start: 104408

End: 105511

Strand: Reverse

Name: namA [H]

Synonym: mll0149

Alternate gene names: 13470442

Gene position: 105511-104408 (Counterclockwise)

Preceding gene: 13470444

Following gene: 13470441

Centisome position: 1.5

GC content: 67.3

Gene sequence:

>1104_bases
ATGACTGCATCGCTTTTCCAGCCGATCACCCTCGACGGCCTCACCTTCCCCAACCGCATCGCCGTGGCGCCGATGTGCCA
GTATTCCGCCGAGGACGGGTCGGCCAGCGACTGGCATCTTTACCACTGGATGAACCTGGCCATGTCCGGCGCCGGCATGG
TCACGGTGGAGATGACCGATGTCGAGCGGCGCGGGCGCATCTCCCATGGTTGCCTCGGGCTTTACTCCGACGACAACGAA
GCCGCCGCGCGCCGCACACTGGACGCGGCACGACGCGTCGCCGCGCCGGGCACGAAATTCGGCACCCAGTTGGCGCACGC
CGGCCGCAAGGCCTCAAATCGCAAGCCCTGGGAGGGCGGCGGGCCACTGCAGCCAAACGAAGACCCCTGGCAGACCGTCT
CGGCCTCGGCCATGGCCTACGACACCGGCTGGAACGTGCCGCGCGCGCTCGATGAGGAAGAGATCCTGCAGCTCATCGAA
CGGTTCGCCCAAGCGGCAAGGCGGGCCGAACGCGCCGGCTTCGACTTCATCGAACTGCACGCAGCACACGGCTATCTGAT
CTTCCAGTTCCTGTCGCCGCTGTCCAACCAGCGCACCGACCGCTGGGGCGGCTCGCTGGAAAACCGGATGCGTCTTGTCG
TCGAAATCGCCAGGGCGGTGAAGAAGGCGGTGCCGAAGCTGATGCTCGGCGCCCGGCTGTCGGTGAAGGACTGGGTCGAC
GGCGGCTTCGACGTCGAGGATGCGATCGAGGTGGCGAAGGCCTTGAAGGCCGAGGGCATCGCCTATCTCTGCTGCTCCAG
CGGCGGCAATTCGCCGTTACAGAAATTGCCCACCGGCCCCGGCTATCAGGTGCATCTGGCAGAAGCCGTGCGCAAGGGCG
CCGGCATCCCGACCCGCGCGGTCGGCCTGATCGACGATCCCCAGCAAGCCGAGGCTGTGATCGCCGAGGGCCGTGCCGAC
ATGGTGGCACTGGCGCGTGCCTTCCTCGCCGATCCGCGCTGGGGCTGGCGTGCGGCCGCCACATTCAAGGAAAAGATCCA
TCCGGCGCCGCAGCTCGCGCGCTCGGTGACGACGATGGAGCACTGGATGAAGGCGGCGGGCTGA

Upstream 100 bases:

>100_bases
TGGGGCAGCGATTGGTCCAGCAAGCGTTTCACTCTCTCGTGTGTGGTATGCAAGATATCTGTCGCCTAGATAACGCGTTC
CCTCTCCCGGAGCCCTCTTC

Downstream 100 bases:

>100_bases
ACCGCCCATTCTCCCGATACCAGCGCGATCCTGACCGGCTCGTTTGCCACAGCCCGCTTCAATTCTGGTCGCAAACTGTT
ACGTTGGGTCAGGCTGCGGC

Product: oxidoreductase

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MTASLFQPITLDGLTFPNRIAVAPMCQYSAEDGSASDWHLYHWMNLAMSGAGMVTVEMTDVERRGRISHGCLGLYSDDNE
AAARRTLDAARRVAAPGTKFGTQLAHAGRKASNRKPWEGGGPLQPNEDPWQTVSASAMAYDTGWNVPRALDEEEILQLIE
RFAQAARRAERAGFDFIELHAAHGYLIFQFLSPLSNQRTDRWGGSLENRMRLVVEIARAVKKAVPKLMLGARLSVKDWVD
GGFDVEDAIEVAKALKAEGIAYLCCSSGGNSPLQKLPTGPGYQVHLAEAVRKGAGIPTRAVGLIDDPQQAEAVIAEGRAD
MVALARAFLADPRWGWRAAATFKEKIHPAPQLARSVTTMEHWMKAAG

Sequences:

>Translated_367_residues
MTASLFQPITLDGLTFPNRIAVAPMCQYSAEDGSASDWHLYHWMNLAMSGAGMVTVEMTDVERRGRISHGCLGLYSDDNE
AAARRTLDAARRVAAPGTKFGTQLAHAGRKASNRKPWEGGGPLQPNEDPWQTVSASAMAYDTGWNVPRALDEEEILQLIE
RFAQAARRAERAGFDFIELHAAHGYLIFQFLSPLSNQRTDRWGGSLENRMRLVVEIARAVKKAVPKLMLGARLSVKDWVD
GGFDVEDAIEVAKALKAEGIAYLCCSSGGNSPLQKLPTGPGYQVHLAEAVRKGAGIPTRAVGLIDDPQQAEAVIAEGRAD
MVALARAFLADPRWGWRAAATFKEKIHPAPQLARSVTTMEHWMKAAG
>Mature_366_residues
TASLFQPITLDGLTFPNRIAVAPMCQYSAEDGSASDWHLYHWMNLAMSGAGMVTVEMTDVERRGRISHGCLGLYSDDNEA
AARRTLDAARRVAAPGTKFGTQLAHAGRKASNRKPWEGGGPLQPNEDPWQTVSASAMAYDTGWNVPRALDEEEILQLIER
FAQAARRAERAGFDFIELHAAHGYLIFQFLSPLSNQRTDRWGGSLENRMRLVVEIARAVKKAVPKLMLGARLSVKDWVDG
GFDVEDAIEVAKALKAEGIAYLCCSSGGNSPLQKLPTGPGYQVHLAEAVRKGAGIPTRAVGLIDDPQQAEAVIAEGRADM
VALARAFLADPRWGWRAAATFKEKIHPAPQLARSVTTMEHWMKAAG

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789463, Length=355, Percent_Identity=31.2676056338028, Blast_Score=144, Evalue=7e-36,
Organism=Escherichia coli, GI1787939, Length=366, Percent_Identity=31.1475409836066, Blast_Score=132, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI17540738, Length=279, Percent_Identity=29.3906810035842, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17565138, Length=199, Percent_Identity=35.1758793969849, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17559802, Length=226, Percent_Identity=31.858407079646, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17564188, Length=175, Percent_Identity=34.8571428571429, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17559804, Length=235, Percent_Identity=31.4893617021277, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI72001454, Length=223, Percent_Identity=32.7354260089686, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17566914, Length=115, Percent_Identity=37.3913043478261, Blast_Score=91, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6321973, Length=90, Percent_Identity=44.4444444444444, Blast_Score=84, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6325086, Length=90, Percent_Identity=41.1111111111111, Blast_Score=81, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 40004; Mature: 39873

Theoretical pI: Translated: 7.64; Mature: 7.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASLFQPITLDGLTFPNRIAVAPMCQYSAEDGSASDWHLYHWMNLAMSGAGMVTVEMTD
CCCCCCCCCEECCCCCCCCEEECHHHHCCCCCCCCCCEEHHHHHHHHHCCCCEEEEEECC
VERRGRISHGCLGLYSDDNEAAARRTLDAARRVAAPGTKFGTQLAHAGRKASNRKPWEGG
CHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCC
GPLQPNEDPWQTVSASAMAYDTGWNVPRALDEEEILQLIERFAQAARRAERAGFDFIELH
CCCCCCCCHHHHHHHHHEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
AAHGYLIFQFLSPLSNQRTDRWGGSLENRMRLVVEIARAVKKAVPKLMLGARLSVKDWVD
CCCHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCC
GGFDVEDAIEVAKALKAEGIAYLCCSSGGNSPLQKLPTGPGYQVHLAEAVRKGAGIPTRA
CCCCHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHCCCCCCCEEEHHHHHHHCCCCCHHE
VGLIDDPQQAEAVIAEGRADMVALARAFLADPRWGWRAAATFKEKIHPAPQLARSVTTME
ECCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHH
HWMKAAG
HHHHHCC
>Mature Secondary Structure 
TASLFQPITLDGLTFPNRIAVAPMCQYSAEDGSASDWHLYHWMNLAMSGAGMVTVEMTD
CCCCCCCCEECCCCCCCCEEECHHHHCCCCCCCCCCEEHHHHHHHHHCCCCEEEEEECC
VERRGRISHGCLGLYSDDNEAAARRTLDAARRVAAPGTKFGTQLAHAGRKASNRKPWEGG
CHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCC
GPLQPNEDPWQTVSASAMAYDTGWNVPRALDEEEILQLIERFAQAARRAERAGFDFIELH
CCCCCCCCHHHHHHHHHEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
AAHGYLIFQFLSPLSNQRTDRWGGSLENRMRLVVEIARAVKKAVPKLMLGARLSVKDWVD
CCCHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCC
GGFDVEDAIEVAKALKAEGIAYLCCSSGGNSPLQKLPTGPGYQVHLAEAVRKGAGIPTRA
CCCCHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHCCCCCCCEEEHHHHHHHCCCCCHHE
VGLIDDPQQAEAVIAEGRADMVALARAFLADPRWGWRAAATFKEKIHPAPQLARSVTTME
ECCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHH
HWMKAAG
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]