Click here to switch to the map view.

The map label for this gene is catE [H]

Identifier: 13470384

GI number: 13470384

Start: 54043

End: 54855

Strand: Direct

Name: catE [H]

Synonym: mlr0078

Alternate gene names: 13470384

Gene position: 54043-54855 (Clockwise)

Preceding gene: 13470381

Following gene: 13470388

Centisome position: 0.77

GC content: 65.44

Gene sequence:

>813_bases
ATGAGCGAACTGCCATTTGCCGCTACCACGCCGGTGAGCGTTGCCCGCGTCGGGTTGAAGGCGCGCGACGCCGAAAGCCT
CGCTGCCTATTACCGCAGGGTTGTCGGCCTGCAGGAATTGAGCCGTGCCGATGGCGCGATCACCCTCGGTGCCGGCAGCC
GTCCGTTGCTGGTCCTCGAGCCGGATGCTTCCGCCAAGCCTGACGATCCGCGCAGCGCCGGCCTGTTCCACACGGCCTTC
CTGCTGCCCAGCCGTGCCGATCTCGGCCGCTGGATCAACCACGCCATATCAGACAAGATCGCCATCGAGGGCGCGTCCGA
CCATCTGGTCAGCGAAGCGCTCTACCTGACCGACCCCGAAGGCAACGGCATCGAGATCTATGCCGACCGCCGGCCGCAGG
ACTGGAAGTGGAACGGCGACAAGATCGCCATGGCGACCGAGCGGCTCAACATTCCGGCTGTCGTCGGCGAAGTACCGGTC
GGCGATGCAGGCTGGCAAGGCGCGCCGGAAAACAGCATTGTCGGCCATGTCCATCTTCGTGTCGGCAGGCCGGAAGAGGC
GGAAGCCTGGTGGAACCAGGAATTCGGCTTCGACACGGTGGCCAAATATGGCGGTCAGGCAGTGTTCCTGTCGTCGGGCC
ATTACCATCATCACATCGGCGCCAATGCCTGGCAGAGCGCCGGCGCCGGCCGTCGCGACCCGTCGCGTTCGGGCCTCGCC
TGGGTCGAGATGCGTTCGGACAATGTGACCGGCGAAACGACCCGTGAGGATCCTTGGGGCACGGTGATCAGGACCGTTCC
GGGAAAGGCGTGA

Upstream 100 bases:

>100_bases
AAGGACCGGGATTTTGGCACTGACACGACGTACAATGATCGGCGGCGCCGGCTTCCTGGCATTGGGAGCTTCATCAAGCG
TTGCCGCAACGGAGACAATG

Downstream 100 bases:

>100_bases
TCGGCTTTGTCCTTCGCGAGTTCGGATACGAAAAGGCCCGCCGGAAAGGCGGGCCTTTTTCTTTGGCGCGTTTAGGTTCT
CAAGCCTCCCCGAACACCCG

Product: hypothetical protein

Products: NA

Alternate protein names: Catechol-induced ring cleavage extradiol dioxygenase [H]

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MSELPFAATTPVSVARVGLKARDAESLAAYYRRVVGLQELSRADGAITLGAGSRPLLVLEPDASAKPDDPRSAGLFHTAF
LLPSRADLGRWINHAISDKIAIEGASDHLVSEALYLTDPEGNGIEIYADRRPQDWKWNGDKIAMATERLNIPAVVGEVPV
GDAGWQGAPENSIVGHVHLRVGRPEEAEAWWNQEFGFDTVAKYGGQAVFLSSGHYHHHIGANAWQSAGAGRRDPSRSGLA
WVEMRSDNVTGETTREDPWGTVIRTVPGKA

Sequences:

>Translated_270_residues
MSELPFAATTPVSVARVGLKARDAESLAAYYRRVVGLQELSRADGAITLGAGSRPLLVLEPDASAKPDDPRSAGLFHTAF
LLPSRADLGRWINHAISDKIAIEGASDHLVSEALYLTDPEGNGIEIYADRRPQDWKWNGDKIAMATERLNIPAVVGEVPV
GDAGWQGAPENSIVGHVHLRVGRPEEAEAWWNQEFGFDTVAKYGGQAVFLSSGHYHHHIGANAWQSAGAGRRDPSRSGLA
WVEMRSDNVTGETTREDPWGTVIRTVPGKA
>Mature_269_residues
SELPFAATTPVSVARVGLKARDAESLAAYYRRVVGLQELSRADGAITLGAGSRPLLVLEPDASAKPDDPRSAGLFHTAFL
LPSRADLGRWINHAISDKIAIEGASDHLVSEALYLTDPEGNGIEIYADRRPQDWKWNGDKIAMATERLNIPAVVGEVPVG
DAGWQGAPENSIVGHVHLRVGRPEEAEAWWNQEFGFDTVAKYGGQAVFLSSGHYHHHIGANAWQSAGAGRRDPSRSGLAW
VEMRSDNVTGETTREDPWGTVIRTVPGKA

Specific function: Involved in the meta cleavage of catechol to 2- hydroxymuconic semialdehyde. Essential for growth and viability in the presence of catechol and probably involved in the detoxification of catechol [H]

COG id: COG2514

COG function: function code R; Predicted ring-cleavage extradiol dioxygenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the extradiol ring-cleavage dioxygenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360
- InterPro:   IPR000486 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: =1.13.11.2 [H]

Molecular weight: Translated: 29191; Mature: 29060

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELPFAATTPVSVARVGLKARDAESLAAYYRRVVGLQELSRADGAITLGAGSRPLLVLE
CCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEEC
PDASAKPDDPRSAGLFHTAFLLPSRADLGRWINHAISDKIAIEGASDHLVSEALYLTDPE
CCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCEEEEECCCHHHHHCEEEEECCC
GNGIEIYADRRPQDWKWNGDKIAMATERLNIPAVVGEVPVGDAGWQGAPENSIVGHVHLR
CCCEEEEECCCCCCCCCCCCEEEEEEECCCCCEEECCCCCCCCCCCCCCCCCEEEEEEEE
VGRPEEAEAWWNQEFGFDTVAKYGGQAVFLSSGHYHHHIGANAWQSAGAGRRDPSRSGLA
ECCCCHHHHHHCCCCCHHHHHHHCCCEEEEECCCEEEECCCCHHHHCCCCCCCCCCCCEE
WVEMRSDNVTGETTREDPWGTVIRTVPGKA
EEEEECCCCCCCCCCCCCCCEEEEECCCCC
>Mature Secondary Structure 
SELPFAATTPVSVARVGLKARDAESLAAYYRRVVGLQELSRADGAITLGAGSRPLLVLE
CCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEEC
PDASAKPDDPRSAGLFHTAFLLPSRADLGRWINHAISDKIAIEGASDHLVSEALYLTDPE
CCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCEEEEECCCHHHHHCEEEEECCC
GNGIEIYADRRPQDWKWNGDKIAMATERLNIPAVVGEVPVGDAGWQGAPENSIVGHVHLR
CCCEEEEECCCCCCCCCCCCEEEEEEECCCCCEEECCCCCCCCCCCCCCCCCEEEEEEEE
VGRPEEAEAWWNQEFGFDTVAKYGGQAVFLSSGHYHHHIGANAWQSAGAGRRDPSRSGLA
ECCCCHHHHHHCCCCCHHHHHHHCCCEEEEECCCEEEECCCCHHHHCCCCCCCCCCCCEE
WVEMRSDNVTGETTREDPWGTVIRTVPGKA
EEEEECCCCCCCCCCCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8704981; 9384377 [H]