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The map label for this gene is rhmA [H]

Identifier: 13470381

GI number: 13470381

Start: 51088

End: 51861

Strand: Direct

Name: rhmA [H]

Synonym: mlr0073

Alternate gene names: 13470381

Gene position: 51088-51861 (Clockwise)

Preceding gene: 13470380

Following gene: 13470384

Centisome position: 0.73

GC content: 63.31

Gene sequence:

>774_bases
ATGTCCCTGAAGTCCCGCCTTGCCGCCGATGAAACGCTGGTCACCGCCTGGTCCGGAGTGCCGGATGCCCTGACCGTCGA
GATCCTCGCCAAACAGGGCTTCGATGCCATCACGCTCGACATGCAGCATGGCGGTCATCACGAGGACAGCGTGCTGCGCG
GTCTTATGCCCGTGCTTGCCGCAAACAAGCCTGCGCTGGTGCGCATCCCCGTCGGCCGTTTCGACATGGCAAGCCGCGCG
CTCGATTTCGGCGCCGAGGCGGTGATCGCGCCGATGGTGAATTCGGTGGCCGATGCAAAGTTGTTCGCCGCGGCAATGAA
ATATCCACCGCTCGGCGAGCGCTCGTGGGGGCCCACCTACGCCTTTCCGCGCCATGGCAAGGGCGACCATGCCGAATGGC
TGCGCGACACCAATCAGCGCACCATGGCCTTTGCCATGGTCGAGACGCGCGCCGCGCTCGACGCGCTCGACGGCATTCTC
GACACGCCGGGCATTGATGGCATCTTCCTCGGCCCATCGGATTTCTCGATCGCCTGGACCAATGGCGCCACGGTCAGTTC
GACCCTGGAGAGCATGATGGAGACGGTGGCGTCGGTGGCCGAGCGCACCCGCAAGGCCGGAAAACATGCCGCGATCTATG
TCGTCGAACCAGCAATTGCCGGCCGTGTCGTCTCGATGGGCTATCGCCTACTCGCCACCGGGTCCGAGCATGCGTTGATT
TCATTGGGGGCAAAGACTCTGCTGAAAGATATCAAGGATTCGATCGGAGCCTGA

Upstream 100 bases:

>100_bases
GACTGGACCAATCGACCGCCCGGCCAAGCCGGGCGGTTTTTCTTTGCCTTCGCCGTGGTTTCCGGCTGAAACTGCCGGCA
TTAACGAGGAAAGAGATTAG

Downstream 100 bases:

>100_bases
ACCCAAACCGGAGGAGCTGCCGTCACGGCGCCGGGCGATCAGGCGCTCGCTGCAGCAGGTGCCGCGGCCATAGGGCCGCC
GCGCCTGAATCTGTTGAACA

Product: 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase

Products: NA

Alternate protein names: KDR aldolase; 2-dehydro-3-deoxyrhamnonate aldolase [H]

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MSLKSRLAADETLVTAWSGVPDALTVEILAKQGFDAITLDMQHGGHHEDSVLRGLMPVLAANKPALVRIPVGRFDMASRA
LDFGAEAVIAPMVNSVADAKLFAAAMKYPPLGERSWGPTYAFPRHGKGDHAEWLRDTNQRTMAFAMVETRAALDALDGIL
DTPGIDGIFLGPSDFSIAWTNGATVSSTLESMMETVASVAERTRKAGKHAAIYVVEPAIAGRVVSMGYRLLATGSEHALI
SLGAKTLLKDIKDSIGA

Sequences:

>Translated_257_residues
MSLKSRLAADETLVTAWSGVPDALTVEILAKQGFDAITLDMQHGGHHEDSVLRGLMPVLAANKPALVRIPVGRFDMASRA
LDFGAEAVIAPMVNSVADAKLFAAAMKYPPLGERSWGPTYAFPRHGKGDHAEWLRDTNQRTMAFAMVETRAALDALDGIL
DTPGIDGIFLGPSDFSIAWTNGATVSSTLESMMETVASVAERTRKAGKHAAIYVVEPAIAGRVVSMGYRLLATGSEHALI
SLGAKTLLKDIKDSIGA
>Mature_256_residues
SLKSRLAADETLVTAWSGVPDALTVEILAKQGFDAITLDMQHGGHHEDSVLRGLMPVLAANKPALVRIPVGRFDMASRAL
DFGAEAVIAPMVNSVADAKLFAAAMKYPPLGERSWGPTYAFPRHGKGDHAEWLRDTNQRTMAFAMVETRAALDALDGILD
TPGIDGIFLGPSDFSIAWTNGATVSSTLESMMETVASVAERTRKAGKHAAIYVVEPAIAGRVVSMGYRLLATGSEHALIS
LGAKTLLKDIKDSIGA

Specific function: Catalyzes the reversible retro-aldol cleavage of 2-keto- 3-deoxy-L-rhamnonate (KDR) to pyruvate and lactaldehyde [H]

COG id: COG3836

COG function: function code G; 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HpcH/HpaI aldolase family. KDR aldolase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788578, Length=240, Percent_Identity=29.5833333333333, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1789514, Length=250, Percent_Identity=26.4, Blast_Score=101, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005000
- InterPro:   IPR015813 [H]

Pfam domain/function: PF03328 HpcH_HpaI [H]

EC number: NA

Molecular weight: Translated: 27315; Mature: 27183

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLKSRLAADETLVTAWSGVPDALTVEILAKQGFDAITLDMQHGGHHEDSVLRGLMPVLA
CCCHHHHCCCHHHEEECCCCCCHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHH
ANKPALVRIPVGRFDMASRALDFGAEAVIAPMVNSVADAKLFAAAMKYPPLGERSWGPTY
CCCCCEEEECCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
AFPRHGKGDHAEWLRDTNQRTMAFAMVETRAALDALDGILDTPGIDGIFLGPSDFSIAWT
CCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEE
NGATVSSTLESMMETVASVAERTRKAGKHAAIYVVEPAIAGRVVSMGYRLLATGSEHALI
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHCEEEEECCCCCEEE
SLGAKTLLKDIKDSIGA
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLKSRLAADETLVTAWSGVPDALTVEILAKQGFDAITLDMQHGGHHEDSVLRGLMPVLA
CCHHHHCCCHHHEEECCCCCCHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHH
ANKPALVRIPVGRFDMASRALDFGAEAVIAPMVNSVADAKLFAAAMKYPPLGERSWGPTY
CCCCCEEEECCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
AFPRHGKGDHAEWLRDTNQRTMAFAMVETRAALDALDGILDTPGIDGIFLGPSDFSIAWT
CCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEE
NGATVSSTLESMMETVASVAERTRKAGKHAAIYVVEPAIAGRVVSMGYRLLATGSEHALI
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHCEEEEECCCCCEEE
SLGAKTLLKDIKDSIGA
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA