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The map label for this gene is lctP [C]

Identifier: 15603717

GI number: 15603717

Start: 2093273

End: 2094859

Strand: Direct

Name: lctP [C]

Synonym: PM1852

Alternate gene names: 15603717

Gene position: 2093273-2094859 (Clockwise)

Preceding gene: 15603716

Following gene: 15603718

Centisome position: 92.73

GC content: 39.32

Gene sequence:

>1587_bases
ATGGTTTTCTTTTTAAGTATTCTTCCTATTGTCTTATTGATTTATTTAATGGTAAAACGTAATAGCTTACCGTCTTATAT
CGCACTTCCTTTGATTGCTGTTTTAACTTATCTCTTACAAGCATTTTATTTTGGGACAGATTTAACCCGTTTAAATGCCA
ATGTCATTGCGGGATTAATTGCGACACAAACACCGATTACAATTATTTTTGGTGCAATTTTATTTAACCGCATGATGGAA
GTATCAGGCAGCACCGATGTATTACGTAAATGGTTAGCCAATATCAATCCGAATCCAGTGGCGCAAATTATGATCATTGG
TTGGGCATTTGCCTTTATGATTGAAGGCGCGAGTGGCTTTGGAACGCCAGCAGCGATTGCCGCGCCAATCTTGATGGGTT
TAGGTTTTAAACCGCTACAAGTGGCAATGCTAGCGTTAGTGATGAACTCTGTGCCGGTTTCTTTCGGTGCGGTTGGTACA
CCAACTTGGTTTGGTTTCGGACCATTAGGATTAAGCGAAGACGTAGTACTTGAAGTGGGGCAGAAAACGGCATTTATTCA
CTTCATTGCAGCCTTTGTGATTCCCGTCTTAGCGTTACGTTTCTTAGTCAGCTGGCAACAAATCAAACAGAATCTTGTTT
TCATTTATATCAGTATTTTAGCTTGTACTATTCCTTATTTCTTATTAGCGCAAGTGAACTATGAGTTCCCTGCTTTAGTG
GGGGGAGCCATCGGTTTATTTATCTCAATTCTCGTGGCGAATAAAGGGATTGGGGTGAGTAAAACAGCGCAGGCAGAAAT
ACAGCTCGAAAAAGTGGAATTTGGCGTACTGGTTAAAGCCTTATTCCCAACCATGATGTTGATTGCGATCTTAATTGTGA
CACGTATTCACCAATTAGGGATTAAGCAATTATTAAATGATGCGACCACCTGGTTCTCTGTATCTTTAGGTGCCTTCGGT
GAATTCAAAGTGAGCCAAGCGTTAATCTTGTCTTTAAACAATATCTTGGGTCAAGGTATTAACGAAAGCTATAAAACTTT
ATATGTGCCTTCACTGATTCCATTTATTGTCACGGTGATCATTTCGATTTTTGTGTTTAAACTCAATGGGACAAAAGCCA
AAACCATTGCGGTGAGCACCTATCAACAAACGAAAAAACCATTCTTTGCGTTATTAGGCGCCTTAGTTATGGTAAAATTA
ATGTTAGTTGGCAATGAGAATTATGATTCTATGGTGATTACTATTGGTAAAACCTTCGCTGATGTTACAGGAGATAAATG
GGTGTATTTCTCCTCTTATCTTGGTGCTATCGGTGCATTTTTCTCAGGATCTAATACTGTTTCAAATTTAACTTTTGGTG
GGATCCAACTCTCTATCGCTGAAACCACAGGCATGTCTGTACCATTAATCCTTGCACTACAATCTGTGGGCGGTGCAATG
GGTAACATGGTGTGTTTGAATAACATTATTGCCGTATGTACTGTATTAAATGTCAGTAACCAAGAAGGTTCGATTTTAAA
ACGGACGGTGGTTCCAATGTTCCTCTATGGTGTTATCGCAGCGTTGGTTGCAGTTGTTATTTACTAA

Upstream 100 bases:

>100_bases
GTAGTTTTATTTTTCATGAAAATACATACTCATAAATAGTTATTCTTTGGCGTTGATATTTTGATGTTATCTCAAATTTA
ATTTTTATGTAGGGTTTTTT

Downstream 100 bases:

>100_bases
TTTATTTTTGATGTCTTTTTTTAAATATAGCTAACTTGCCCGAGTTAGCTATATCCGCATTTATTGGAGTGATGAAAATG
AATGTCAATTTTTATGTGAC

Product: LctP

Products: Proton [Cytoplasm]; lactate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 528; Mature: 528

Protein sequence:

>528_residues
MVFFLSILPIVLLIYLMVKRNSLPSYIALPLIAVLTYLLQAFYFGTDLTRLNANVIAGLIATQTPITIIFGAILFNRMME
VSGSTDVLRKWLANINPNPVAQIMIIGWAFAFMIEGASGFGTPAAIAAPILMGLGFKPLQVAMLALVMNSVPVSFGAVGT
PTWFGFGPLGLSEDVVLEVGQKTAFIHFIAAFVIPVLALRFLVSWQQIKQNLVFIYISILACTIPYFLLAQVNYEFPALV
GGAIGLFISILVANKGIGVSKTAQAEIQLEKVEFGVLVKALFPTMMLIAILIVTRIHQLGIKQLLNDATTWFSVSLGAFG
EFKVSQALILSLNNILGQGINESYKTLYVPSLIPFIVTVIISIFVFKLNGTKAKTIAVSTYQQTKKPFFALLGALVMVKL
MLVGNENYDSMVITIGKTFADVTGDKWVYFSSYLGAIGAFFSGSNTVSNLTFGGIQLSIAETTGMSVPLILALQSVGGAM
GNMVCLNNIIAVCTVLNVSNQEGSILKRTVVPMFLYGVIAALVAVVIY

Sequences:

>Translated_528_residues
MVFFLSILPIVLLIYLMVKRNSLPSYIALPLIAVLTYLLQAFYFGTDLTRLNANVIAGLIATQTPITIIFGAILFNRMME
VSGSTDVLRKWLANINPNPVAQIMIIGWAFAFMIEGASGFGTPAAIAAPILMGLGFKPLQVAMLALVMNSVPVSFGAVGT
PTWFGFGPLGLSEDVVLEVGQKTAFIHFIAAFVIPVLALRFLVSWQQIKQNLVFIYISILACTIPYFLLAQVNYEFPALV
GGAIGLFISILVANKGIGVSKTAQAEIQLEKVEFGVLVKALFPTMMLIAILIVTRIHQLGIKQLLNDATTWFSVSLGAFG
EFKVSQALILSLNNILGQGINESYKTLYVPSLIPFIVTVIISIFVFKLNGTKAKTIAVSTYQQTKKPFFALLGALVMVKL
MLVGNENYDSMVITIGKTFADVTGDKWVYFSSYLGAIGAFFSGSNTVSNLTFGGIQLSIAETTGMSVPLILALQSVGGAM
GNMVCLNNIIAVCTVLNVSNQEGSILKRTVVPMFLYGVIAALVAVVIY
>Mature_528_residues
MVFFLSILPIVLLIYLMVKRNSLPSYIALPLIAVLTYLLQAFYFGTDLTRLNANVIAGLIATQTPITIIFGAILFNRMME
VSGSTDVLRKWLANINPNPVAQIMIIGWAFAFMIEGASGFGTPAAIAAPILMGLGFKPLQVAMLALVMNSVPVSFGAVGT
PTWFGFGPLGLSEDVVLEVGQKTAFIHFIAAFVIPVLALRFLVSWQQIKQNLVFIYISILACTIPYFLLAQVNYEFPALV
GGAIGLFISILVANKGIGVSKTAQAEIQLEKVEFGVLVKALFPTMMLIAILIVTRIHQLGIKQLLNDATTWFSVSLGAFG
EFKVSQALILSLNNILGQGINESYKTLYVPSLIPFIVTVIISIFVFKLNGTKAKTIAVSTYQQTKKPFFALLGALVMVKL
MLVGNENYDSMVITIGKTFADVTGDKWVYFSSYLGAIGAFFSGSNTVSNLTFGGIQLSIAETTGMSVPLILALQSVGGAM
GNMVCLNNIIAVCTVLNVSNQEGSILKRTVVPMFLYGVIAALVAVVIY

Specific function: May play a role in L-lactate transport [H]

COG id: COG1620

COG function: function code C; L-lactate permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lactate permease family [H]

Homologues:

Organism=Escherichia coli, GI1790031, Length=543, Percent_Identity=25.2302025782689, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1789347, Length=159, Percent_Identity=35.2201257861635, Blast_Score=86, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003804 [H]

Pfam domain/function: PF02652 Lactate_perm [H]

EC number: NA

Molecular weight: Translated: 56928; Mature: 56928

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVFFLSILPIVLLIYLMVKRNSLPSYIALPLIAVLTYLLQAFYFGTDLTRLNANVIAGLI
CEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ATQTPITIIFGAILFNRMMEVSGSTDVLRKWLANINPNPVAQIMIIGWAFAFMIEGASGF
HCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCC
GTPAAIAAPILMGLGFKPLQVAMLALVMNSVPVSFGAVGTPTWFGFGPLGLSEDVVLEVG
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCC
QKTAFIHFIAAFVIPVLALRFLVSWQQIKQNLVFIYISILACTIPYFLLAQVNYEFPALV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
GGAIGLFISILVANKGIGVSKTAQAEIQLEKVEFGVLVKALFPTMMLIAILIVTRIHQLG
HHHHHHHHHHHHHCCCCCCCCCCHHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IKQLLNDATTWFSVSLGAFGEFKVSQALILSLNNILGQGINESYKTLYVPSLIPFIVTVI
HHHHHHCHHHHEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHEEEHHHHHHHHHHHH
ISIFVFKLNGTKAKTIAVSTYQQTKKPFFALLGALVMVKLMLVGNENYDSMVITIGKTFA
HHHHHEEECCCCEEEEEEEHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHH
DVTGDKWVYFSSYLGAIGAFFSGSNTVSNLTFGGIQLSIAETTGMSVPLILALQSVGGAM
HCCCCCEEHHHHHHHHHHHHHCCCCCCCCEEECCEEEEEECCCCCCHHHHHHHHHHCCHH
GNMVCLNNIIAVCTVLNVSNQEGSILKRTVVPMFLYGVIAALVAVVIY
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVFFLSILPIVLLIYLMVKRNSLPSYIALPLIAVLTYLLQAFYFGTDLTRLNANVIAGLI
CEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ATQTPITIIFGAILFNRMMEVSGSTDVLRKWLANINPNPVAQIMIIGWAFAFMIEGASGF
HCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCC
GTPAAIAAPILMGLGFKPLQVAMLALVMNSVPVSFGAVGTPTWFGFGPLGLSEDVVLEVG
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCC
QKTAFIHFIAAFVIPVLALRFLVSWQQIKQNLVFIYISILACTIPYFLLAQVNYEFPALV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
GGAIGLFISILVANKGIGVSKTAQAEIQLEKVEFGVLVKALFPTMMLIAILIVTRIHQLG
HHHHHHHHHHHHHCCCCCCCCCCHHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IKQLLNDATTWFSVSLGAFGEFKVSQALILSLNNILGQGINESYKTLYVPSLIPFIVTVI
HHHHHHCHHHHEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHEEEHHHHHHHHHHHH
ISIFVFKLNGTKAKTIAVSTYQQTKKPFFALLGALVMVKLMLVGNENYDSMVITIGKTFA
HHHHHEEECCCCEEEEEEEHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHH
DVTGDKWVYFSSYLGAIGAFFSGSNTVSNLTFGGIQLSIAETTGMSVPLILALQSVGGAM
HCCCCCEEHHHHHHHHHHHHHCCCCCCCCEEECCEEEEEECCCCCCHHHHHHHHHHCCHH
GNMVCLNNIIAVCTVLNVSNQEGSILKRTVVPMFLYGVIAALVAVVIY
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; lactate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + lactate [Periplasm] = Proton [Cytoplasm] + lactate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]