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The map label for this gene is rfaC [H]

Identifier: 15603708

GI number: 15603708

Start: 2083018

End: 2083983

Strand: Reverse

Name: rfaC [H]

Synonym: PM1843

Alternate gene names: 15603708

Gene position: 2083983-2083018 (Counterclockwise)

Preceding gene: 15603709

Following gene: 15603704

Centisome position: 92.31

GC content: 45.86

Gene sequence:

>966_bases
ATGAAAATTTGTTTAGTCAAAACCTCATCAATGGGCGATATTCTGCACAGTTTACCTGCGCTCACCGATGCCCAACGCGC
CCTCCCCAATTTACAAGTTGATTGGGTGGTCGAAGAAAGTTTCGCTGAAATTCCCCATTGGCATAGCGCCGTCCGACAGG
TTATCCCCATTGCTCTGCGACGTTGGCGTAAAACCCCGTTTACCGCCCTAACTCGAAAACAGTGGAAAACTTACCGCACT
TTATTACAATCAGAACAATATGATGCGGTCATTGATGCACAAGGCTTACTTAAAAGTGCCCTTTTTGCCACTCGATTAGC
ACGTGGCACACGCCATGGTTACGATCGTCATTCGATTCGTGAACCGATTGCCGCCTGTTTCTACGATAAAAAATACGCCA
TTAGCTATCAACAACATGCTGTCGAACGTATTCGCCAGCTGTTTGCACAAAGCCTAAATTATCCCTTGCCCCATACACAA
GGCGATTACGGCATAGCACGCCATTTCCCACAACACGCACAAACGATGCCCTATGTCCTCTTTTTCCATGGCACCACACG
CCAAGATAAATTTCTACCGGACAGACAATGGCGGACATTAGCAGAAAAACTGACCGCACAGGGTATCCAAATTCACGTAC
CTTGGTCAAATTCTCAAGAAAAACAGCGTGCAGAGAGGATCGCCCAAGGGCTTGATCTTGTAACGATTTTGCCAAAATCC
ACATTATCCGAGTTAGCACAGCAGATTGTGAATGCCAGCGCTGTTGTTTCTGTTGACACCGGATTGGCACATTTAAGTGC
CGCACTCGATAAAACCAACTTGACTCTCTATGGTGCCACGGATCCCAAACTGATAGGCTCCTACGGCAAAAACCAGCATT
ATCTCGTTGCTGAGAGTATGGATAAGATTGAAGCTGATGAAATTTTCCAAAAATTGACCGCACTTTTATCGTTAAACACG
ATATAA

Upstream 100 bases:

>100_bases
TGCGTAAAGGCAAAGACAGTGACGAAGGTTACCATCAAAGTTTAATTGATATTCAACCGGAATTGGTATTCGATAAACTC
ACAGGATTACTTGCTAACAC

Downstream 100 bases:

>100_bases
GCTAACAGACCGATCCCCATATCCAACTGTTTTAGTCATATACCAACAGTCAATTGAAACTGCCTATACGGCAGTTAACT
CTTGAAAGCAACAGCAGACA

Product: ADP-heptose:LPS heptosyl transferase I

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MKICLVKTSSMGDILHSLPALTDAQRALPNLQVDWVVEESFAEIPHWHSAVRQVIPIALRRWRKTPFTALTRKQWKTYRT
LLQSEQYDAVIDAQGLLKSALFATRLARGTRHGYDRHSIREPIAACFYDKKYAISYQQHAVERIRQLFAQSLNYPLPHTQ
GDYGIARHFPQHAQTMPYVLFFHGTTRQDKFLPDRQWRTLAEKLTAQGIQIHVPWSNSQEKQRAERIAQGLDLVTILPKS
TLSELAQQIVNASAVVSVDTGLAHLSAALDKTNLTLYGATDPKLIGSYGKNQHYLVAESMDKIEADEIFQKLTALLSLNT
I

Sequences:

>Translated_321_residues
MKICLVKTSSMGDILHSLPALTDAQRALPNLQVDWVVEESFAEIPHWHSAVRQVIPIALRRWRKTPFTALTRKQWKTYRT
LLQSEQYDAVIDAQGLLKSALFATRLARGTRHGYDRHSIREPIAACFYDKKYAISYQQHAVERIRQLFAQSLNYPLPHTQ
GDYGIARHFPQHAQTMPYVLFFHGTTRQDKFLPDRQWRTLAEKLTAQGIQIHVPWSNSQEKQRAERIAQGLDLVTILPKS
TLSELAQQIVNASAVVSVDTGLAHLSAALDKTNLTLYGATDPKLIGSYGKNQHYLVAESMDKIEADEIFQKLTALLSLNT
I
>Mature_321_residues
MKICLVKTSSMGDILHSLPALTDAQRALPNLQVDWVVEESFAEIPHWHSAVRQVIPIALRRWRKTPFTALTRKQWKTYRT
LLQSEQYDAVIDAQGLLKSALFATRLARGTRHGYDRHSIREPIAACFYDKKYAISYQQHAVERIRQLFAQSLNYPLPHTQ
GDYGIARHFPQHAQTMPYVLFFHGTTRQDKFLPDRQWRTLAEKLTAQGIQIHVPWSNSQEKQRAERIAQGLDLVTILPKS
TLSELAQQIVNASAVVSVDTGLAHLSAALDKTNLTLYGATDPKLIGSYGKNQHYLVAESMDKIEADEIFQKLTALLSLNT
I

Specific function: Heptose transfer to the lipopolysaccharide core. It transfers the innnermost heptose to [4'-P](3-deoxy-D-manno- octulosonic acid)2-IVA [H]

COG id: COG0859

COG function: function code M; ADP-heptose:LPS heptosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 9 family [H]

Homologues:

Organism=Escherichia coli, GI1790051, Length=319, Percent_Identity=53.2915360501567, Blast_Score=355, Evalue=2e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002201
- InterPro:   IPR011908 [H]

Pfam domain/function: PF01075 Glyco_transf_9 [H]

EC number: 2.4.1.-

Molecular weight: Translated: 36454; Mature: 36454

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKICLVKTSSMGDILHSLPALTDAQRALPNLQVDWVVEESFAEIPHWHSAVRQVIPIALR
CEEEEEECCCHHHHHHHHHCHHHHHHHCCCCEEEEEEHHHHHHCCHHHHHHHHHHHHHHH
RWRKTPFTALTRKQWKTYRTLLQSEQYDAVIDAQGLLKSALFATRLARGTRHGYDRHSIR
HHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
EPIAACFYDKKYAISYQQHAVERIRQLFAQSLNYPLPHTQGDYGIARHFPQHAQTMPYVL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCHHHCCCCEEE
FFHGTTRQDKFLPDRQWRTLAEKLTAQGIQIHVPWSNSQEKQRAERIAQGLDLVTILPKS
EEECCCCCCCCCCCHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHCCCCEEEECCHH
TLSELAQQIVNASAVVSVDTGLAHLSAALDKTNLTLYGATDPKLIGSYGKNQHYLVAESM
HHHHHHHHHHCCHHEEEEHHHHHHHHHHHHHCCEEEEECCCCHHHHCCCCCCEEEEHHHH
DKIEADEIFQKLTALLSLNTI
HHCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKICLVKTSSMGDILHSLPALTDAQRALPNLQVDWVVEESFAEIPHWHSAVRQVIPIALR
CEEEEEECCCHHHHHHHHHCHHHHHHHCCCCEEEEEEHHHHHHCCHHHHHHHHHHHHHHH
RWRKTPFTALTRKQWKTYRTLLQSEQYDAVIDAQGLLKSALFATRLARGTRHGYDRHSIR
HHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
EPIAACFYDKKYAISYQQHAVERIRQLFAQSLNYPLPHTQGDYGIARHFPQHAQTMPYVL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCHHHCCCCEEE
FFHGTTRQDKFLPDRQWRTLAEKLTAQGIQIHVPWSNSQEKQRAERIAQGLDLVTILPKS
EEECCCCCCCCCCCHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHCCCCEEEECCHH
TLSELAQQIVNASAVVSVDTGLAHLSAALDKTNLTLYGATDPKLIGSYGKNQHYLVAESM
HHHHHHHHHHCCHHEEEEHHHHHHHHHHHHHCCEEEEECCCCHHHHCCCCCCEEEEHHHH
DKIEADEIFQKLTALLSLNTI
HHCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8478319; 8041620; 9278503; 1624462 [H]