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The map label for this gene is mclA [H]

Identifier: 15603653

GI number: 15603653

Start: 2012430

End: 2013020

Strand: Reverse

Name: mclA [H]

Synonym: PM1788

Alternate gene names: 15603653

Gene position: 2013020-2012430 (Counterclockwise)

Preceding gene: 15603654

Following gene: 15603652

Centisome position: 89.17

GC content: 39.59

Gene sequence:

>591_bases
ATGCAAAAAGAGTTACTTTCAGCCTATATTGATGGTGAACAAGTCAGCGCTGAATTGACTGAAAAATTATGCCAAGATGA
CGAATTACAGCAATCTTGGGCAAATTTTCATACAATTCGTGCAGTCATGCGTCAAGAAAGCGAAGTATTACTGGGTGCAG
ATTTTACCGCGAAAATGGAAGCGCTCATTGAAGCAGAGGAAATGAAAGTCGTCACACCGATGATTTCACAACCGTTGCCA
GAAGAAGTAGAACACTTACCATTTATGCAAAAACTCAAAGGTCTTTTTGCTCCCTTGGCACAAGTCGCTGTGGCGGCAAG
CGTTTGCTTAGTTGCGGTGCTCGGCACACAATCTGTGATTACGGCTAAGAATGAAGCACAAAACAATGTTGATGCGCCAA
TTTTACAAACCTTACCGTTTAATAATGTCGTACAGCAAGTAAGTTATAATGCACCGATTAAAGATGTAGTCACACCAGAG
CAATTGGAACAAAAAAATAAACGCATTGGTGCAATGTTACAAAACTATGAAGTACAACGTCGTCTTTATGCTGACTCTTT
AATCTTAAATCAGCAAAACACACAAAAATAA

Upstream 100 bases:

>100_bases
TTCCGTGCGCGTGAAATTATCGAAAGTAAAGTGCAACCTATGTTGCAACGTTAAATACAATACAAAAAATCCAAAACCAA
GCAAAAGTTGGAGTGTCCAA

Downstream 100 bases:

>100_bases
TGTTTTTCGTTAATTCACCTTCACCACCTTTATAGGTGGTGAATTTGTTTTATGGTGGCAACTATGTTTAAAGCACTGCA
AAAATCTCTCACCTTTTTCT

Product: MclA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MQKELLSAYIDGEQVSAELTEKLCQDDELQQSWANFHTIRAVMRQESEVLLGADFTAKMEALIEAEEMKVVTPMISQPLP
EEVEHLPFMQKLKGLFAPLAQVAVAASVCLVAVLGTQSVITAKNEAQNNVDAPILQTLPFNNVVQQVSYNAPIKDVVTPE
QLEQKNKRIGAMLQNYEVQRRLYADSLILNQQNTQK

Sequences:

>Translated_196_residues
MQKELLSAYIDGEQVSAELTEKLCQDDELQQSWANFHTIRAVMRQESEVLLGADFTAKMEALIEAEEMKVVTPMISQPLP
EEVEHLPFMQKLKGLFAPLAQVAVAASVCLVAVLGTQSVITAKNEAQNNVDAPILQTLPFNNVVQQVSYNAPIKDVVTPE
QLEQKNKRIGAMLQNYEVQRRLYADSLILNQQNTQK
>Mature_196_residues
MQKELLSAYIDGEQVSAELTEKLCQDDELQQSWANFHTIRAVMRQESEVLLGADFTAKMEALIEAEEMKVVTPMISQPLP
EEVEHLPFMQKLKGLFAPLAQVAVAASVCLVAVLGTQSVITAKNEAQNNVDAPILQTLPFNNVVQQVSYNAPIKDVVTPE
QLEQKNKRIGAMLQNYEVQRRLYADSLILNQQNTQK

Specific function: Negative regulator of rpoE [H]

COG id: COG3073

COG function: function code T; Negative regulator of sigma E activity

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rseA family [H]

Homologues:

Organism=Escherichia coli, GI1788925, Length=192, Percent_Identity=34.8958333333333, Blast_Score=112, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005573
- InterPro:   IPR005572 [H]

Pfam domain/function: PF03873 RseA_C; PF03872 RseA_N [H]

EC number: NA

Molecular weight: Translated: 21924; Mature: 21924

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKELLSAYIDGEQVSAELTEKLCQDDELQQSWANFHTIRAVMRQESEVLLGADFTAKME
CCHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHH
ALIEAEEMKVVTPMISQPLPEEVEHLPFMQKLKGLFAPLAQVAVAASVCLVAVLGTQSVI
HHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
TAKNEAQNNVDAPILQTLPFNNVVQQVSYNAPIKDVVTPEQLEQKNKRIGAMLQNYEVQR
CCCHHHCCCCCCCHHHHCCHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHH
RLYADSLILNQQNTQK
HHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQKELLSAYIDGEQVSAELTEKLCQDDELQQSWANFHTIRAVMRQESEVLLGADFTAKME
CCHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHH
ALIEAEEMKVVTPMISQPLPEEVEHLPFMQKLKGLFAPLAQVAVAASVCLVAVLGTQSVI
HHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
TAKNEAQNNVDAPILQTLPFNNVVQQVSYNAPIKDVVTPEQLEQKNKRIGAMLQNYEVQR
CCCHHHCCCCCCCHHHHCCHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHH
RLYADSLILNQQNTQK
HHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]