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The map label for this gene is siaP [H]

Identifier: 15603574

GI number: 15603574

Start: 1917948

End: 1918931

Strand: Reverse

Name: siaP [H]

Synonym: PM1709

Alternate gene names: 15603574

Gene position: 1918931-1917948 (Counterclockwise)

Preceding gene: 15603581

Following gene: 15603573

Centisome position: 85.0

GC content: 37.3

Gene sequence:

>984_bases
ATGAAATTTAAAAAACTACTACTTGCATCTTTATGTTTAGGTGTTTCAGCTTCTGTATTTGCAGCAGATTACGATCTTAA
ATTCGGTATGGTTGCGGGTCCAAGCTCAAACGAATATAAAGCAGTAGAATTCTTTGCGAAAGAAGTGAAAGAAAAATCCA
ATGGCAAAATTGATGTGGCTATTTTCCCTAGCTCACAGTTAGGTGATGACCGTGTGATGATTAAACAATTAAAAGACGGT
GCATTAGACTTTACGTTAGGTGAATCAGCACGTTTCCAAATTTACTTCCCAGAAGCAGAAGTATTTGCGTTGCCTTATAT
GATTCCTAATTTTGAAACCTCTAAAAAAGCGTTGCTCGACACAAAATTTGGTCAAGGTTTATTGAAAAAAATTGATAAAG
AGTTAAACGTACAAGTGTTATCTGTGGCGTATAACGGTACACGTCAAACAACTTCTAACCGTGCAATCAACAGCATTGAA
GACATGAAAGGGTTAAAATTACGTGTACCTAACGCGGCAACCAACCTTGCTTATGCAAAATACGTGGGTGCAGCGCCAAC
ACCAATGGCATTCTCTGAAGTTTACCTTGCACTTCAAACAAACTCTGTGGATGGTCAAGAAAACCCATTACCGACAATCC
AAGCACAAAAATTCTATGAAGTACAAAAATACTTAGCATTAACTAACCACATCTTAAATGACCAACTTTACTTAATCAGT
AACGATACGTTGGCAGATTTACCAGAAGATTTACAAAAAGTGGTTAAAGATGCAGCAGCGAAAGCCGCTGAATATCACAC
TAAACTCTTCGTTGACGGTGAGAACAGCTTAGTTGAGTTCTTCAAAAGTCAAGGTGTGACAGTCACACAACCAGACTTAA
AACCATTTAAAGCAGCACTTACACCATACTATGATGAATATCTCAAGAAAAATGGTGAAGTCGGTAAAATGGCGATTGAA
GAAATTTCTAATCTCGCTAAATAA

Upstream 100 bases:

>100_bases
ATAAAAAATAGTTTTTTCACTTTAGAATGCCAAACGTGTGAAATTTATTTCATCATCATTTTAACGTAATCCCAACGTAA
CCAATAGAGGAGAACTCATA

Downstream 100 bases:

>100_bases
ATATAGTAACCTTATCCCTGCGCCTTAAGGGATAAGGTTCCTTTTTATTGGGTTGTCTTGAGGTATCTATGAAAATAATA
AATAAATTAGAAGAGTGGAT

Product: hypothetical protein

Products: NA

Alternate protein names: Extracytoplasmic solute receptor protein siaP; N-acetylneuraminic-binding protein; Neu5Ac-binding protein [H]

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MKFKKLLLASLCLGVSASVFAADYDLKFGMVAGPSSNEYKAVEFFAKEVKEKSNGKIDVAIFPSSQLGDDRVMIKQLKDG
ALDFTLGESARFQIYFPEAEVFALPYMIPNFETSKKALLDTKFGQGLLKKIDKELNVQVLSVAYNGTRQTTSNRAINSIE
DMKGLKLRVPNAATNLAYAKYVGAAPTPMAFSEVYLALQTNSVDGQENPLPTIQAQKFYEVQKYLALTNHILNDQLYLIS
NDTLADLPEDLQKVVKDAAAKAAEYHTKLFVDGENSLVEFFKSQGVTVTQPDLKPFKAALTPYYDEYLKKNGEVGKMAIE
EISNLAK

Sequences:

>Translated_327_residues
MKFKKLLLASLCLGVSASVFAADYDLKFGMVAGPSSNEYKAVEFFAKEVKEKSNGKIDVAIFPSSQLGDDRVMIKQLKDG
ALDFTLGESARFQIYFPEAEVFALPYMIPNFETSKKALLDTKFGQGLLKKIDKELNVQVLSVAYNGTRQTTSNRAINSIE
DMKGLKLRVPNAATNLAYAKYVGAAPTPMAFSEVYLALQTNSVDGQENPLPTIQAQKFYEVQKYLALTNHILNDQLYLIS
NDTLADLPEDLQKVVKDAAAKAAEYHTKLFVDGENSLVEFFKSQGVTVTQPDLKPFKAALTPYYDEYLKKNGEVGKMAIE
EISNLAK
>Mature_327_residues
MKFKKLLLASLCLGVSASVFAADYDLKFGMVAGPSSNEYKAVEFFAKEVKEKSNGKIDVAIFPSSQLGDDRVMIKQLKDG
ALDFTLGESARFQIYFPEAEVFALPYMIPNFETSKKALLDTKFGQGLLKKIDKELNVQVLSVAYNGTRQTTSNRAINSIE
DMKGLKLRVPNAATNLAYAKYVGAAPTPMAFSEVYLALQTNSVDGQENPLPTIQAQKFYEVQKYLALTNHILNDQLYLIS
NDTLADLPEDLQKVVKDAAAKAAEYHTKLFVDGENSLVEFFKSQGVTVTQPDLKPFKAALTPYYDEYLKKNGEVGKMAIE
EISNLAK

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid. This protein specifically binds sialic acid [H]

COG id: COG1638

COG function: function code G; TRAP-type C4-dicarboxylate transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 7 family [H]

Homologues:

Organism=Escherichia coli, GI1790004, Length=305, Percent_Identity=31.4754098360656, Blast_Score=154, Evalue=9e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018389
- InterPro:   IPR004682 [H]

Pfam domain/function: PF03480 SBP_bac_7 [H]

EC number: NA

Molecular weight: Translated: 36209; Mature: 36209

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFKKLLLASLCLGVSASVFAADYDLKFGMVAGPSSNEYKAVEFFAKEVKEKSNGKIDVA
CCHHHHHHHHHHHCCCCHHEEEECCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEE
IFPSSQLGDDRVMIKQLKDGALDFTLGESARFQIYFPEAEVFALPYMIPNFETSKKALLD
ECCCCCCCCHHHHHHHHCCCCEEEEECCCCEEEEECCCCCEEEECEECCCCCCCHHHHHH
TKFGQGLLKKIDKELNVQVLSVAYNGTRQTTSNRAINSIEDMKGLKLRVPNAATNLAYAK
HHHCHHHHHHHHHHCCEEEEEEEECCCCCCCCCHHHHHHHHCCCCEEECCCCHHHHHHHH
YVGAAPTPMAFSEVYLALQTNSVDGQENPLPTIQAQKFYEVQKYLALTNHILNDQLYLIS
HCCCCCCCCHHEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEE
NDTLADLPEDLQKVVKDAAAKAAEYHTKLFVDGENSLVEFFKSQGVTVTQPDLKPFKAAL
CCCHHHCHHHHHHHHHHHHHHHHHHCEEEEECCCHHHHHHHHHCCCEEECCCCHHHHHHH
TPYYDEYLKKNGEVGKMAIEEISNLAK
CHHHHHHHHCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKFKKLLLASLCLGVSASVFAADYDLKFGMVAGPSSNEYKAVEFFAKEVKEKSNGKIDVA
CCHHHHHHHHHHHCCCCHHEEEECCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEE
IFPSSQLGDDRVMIKQLKDGALDFTLGESARFQIYFPEAEVFALPYMIPNFETSKKALLD
ECCCCCCCCHHHHHHHHCCCCEEEEECCCCEEEEECCCCCEEEECEECCCCCCCHHHHHH
TKFGQGLLKKIDKELNVQVLSVAYNGTRQTTSNRAINSIEDMKGLKLRVPNAATNLAYAK
HHHCHHHHHHHHHHCCEEEEEEEECCCCCCCCCHHHHHHHHCCCCEEECCCCHHHHHHHH
YVGAAPTPMAFSEVYLALQTNSVDGQENPLPTIQAQKFYEVQKYLALTNHILNDQLYLIS
HCCCCCCCCHHEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEE
NDTLADLPEDLQKVVKDAAAKAAEYHTKLFVDGENSLVEFFKSQGVTVTQPDLKPFKAAL
CCCHHHCHHHHHHHHHHHHHHHHHHCEEEEECCCHHHHHHHHHCCCEEECCCCHHHHHHH
TPYYDEYLKKNGEVGKMAIEEISNLAK
CHHHHHHHHCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA