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The map label for this gene is trx [H]

Identifier: 15603570

GI number: 15603570

Start: 1913515

End: 1913889

Strand: Direct

Name: trx [H]

Synonym: PM1705

Alternate gene names: 15603570

Gene position: 1913515-1913889 (Clockwise)

Preceding gene: 15603569

Following gene: 15603571

Centisome position: 84.76

GC content: 39.2

Gene sequence:

>375_bases
ATGAAAAAACTTTTGACCTTCGTTGCTACTTGCTTACTGTCCGTTCAAGCTTTTGCGGTGGATTTCAAACCATTTGAACA
AGCAGCATTTGATGTAGCCCTACAAAGCGATAAACCGGTTTTAGTCGATGTTTATGCCAATTGGTGTCCAACTTGCAAAC
GTCAAGTCAACGTACTTGAGCCAATGTTAAAAGAGGCACAATTTAAAGATTACACTGTCTTTAAAGTGGATTATGACGAA
CATAAAGATGCTTTAAAACATTTCAATGTCACTCGTCAAAGTACCTTAATTCTGTTTAACCAAGGCAAAGAAGTACGCCG
CAGTATTGCTGAAACAAGCGAAGACGGTTTGCGTCGTTTTATCACCCTCCCATAA

Upstream 100 bases:

>100_bases
GCGGTCATCTTTTACAAAGTTTCTGTAAGGATTTCTCTCTTCCTTCGTCTAAATCACCATATCGCTACCATTTATGTTTA
ATTTACTTTAGGAGAACTTT

Downstream 100 bases:

>100_bases
GGAAACTGACATAATATGGATATCAGTGTCACCGTTTTAGGCTTAAGTTTACTGGCAGGATTGCTTACTACTCTTTCCCC
ATGTGTTTTACCTATTCTGC

Product: Trx

Products: NA

Alternate protein names: Trx; MPT46 [H]

Number of amino acids: Translated: 124; Mature: 124

Protein sequence:

>124_residues
MKKLLTFVATCLLSVQAFAVDFKPFEQAAFDVALQSDKPVLVDVYANWCPTCKRQVNVLEPMLKEAQFKDYTVFKVDYDE
HKDALKHFNVTRQSTLILFNQGKEVRRSIAETSEDGLRRFITLP

Sequences:

>Translated_124_residues
MKKLLTFVATCLLSVQAFAVDFKPFEQAAFDVALQSDKPVLVDVYANWCPTCKRQVNVLEPMLKEAQFKDYTVFKVDYDE
HKDALKHFNVTRQSTLILFNQGKEVRRSIAETSEDGLRRFITLP
>Mature_124_residues
MKKLLTFVATCLLSVQAFAVDFKPFEQAAFDVALQSDKPVLVDVYANWCPTCKRQVNVLEPMLKEAQFKDYTVFKVDYDE
HKDALKHFNVTRQSTLILFNQGKEVRRSIAETSEDGLRRFITLP

Specific function: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: NA

Molecular weight: Translated: 14306; Mature: 14306

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLLTFVATCLLSVQAFAVDFKPFEQAAFDVALQSDKPVLVDVYANWCPTCKRQVNVLE
CHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHH
PMLKEAQFKDYTVFKVDYDEHKDALKHFNVTRQSTLILFNQGKEVRRSIAETSEDGLRRF
HHHHHCCCCCEEEEEEECHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHCCHHHHHHH
ITLP
CCCC
>Mature Secondary Structure
MKKLLTFVATCLLSVQAFAVDFKPFEQAAFDVALQSDKPVLVDVYANWCPTCKRQVNVLE
CHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHH
PMLKEAQFKDYTVFKVDYDEHKDALKHFNVTRQSTLILFNQGKEVRRSIAETSEDGLRRF
HHHHHCCCCCEEEEEEECHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHCCHHHHHHH
ITLP
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Reduction reactions; participates in dithiol-disulfide exchange reactions [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]