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The map label for this gene is clpB

Identifier: 15603569

GI number: 15603569

Start: 1910791

End: 1913358

Strand: Direct

Name: clpB

Synonym: PM1704

Alternate gene names: 15603569

Gene position: 1910791-1913358 (Clockwise)

Preceding gene: 15603563

Following gene: 15603570

Centisome position: 84.64

GC content: 43.81

Gene sequence:

>2568_bases
ATGAATATCGAAAAATTTACGACAAAATTTCAACAAGCACTGCAAGAGGCGCAATCTTTAGCCATTGGCAAAGATAACCA
ATTTATTGAACCCGTCCATTTACTCACCGCCTTGTTAAATCAACAAGGTGGTTCCACTGCGCCAATTTTAACAGCAAGTG
GGGCAAACTTACCGCTCTTGCGTAATGAATTAAATGCCGAGCTCAGTAAATTACCACAAGTGTCAGGCAGCGGTGGTGAT
GTACAAGTTTCACGGAGTTTAGTGAATCTATTAAACTTGTGCGACAAGTTAGCACAGCAACGCCAAGATAAATTTATTTC
CTCTGAATTGTTTTTACTGGCAGCGTTAGAAGACAAAACACTTGGTGATGTGTTGAAAAAGTGCGGTGTGAAAAAAGAAA
ATTTACAACAGGCAATAGAGAAAGTCCGTGGCGGACAAAATGTGAATGATCCAAATGCGGAAGAAAGTCGCCAAGCGTTA
GAAAAATATACGATTGATTTAACCGCGCGTGCAGAAAGCGGCAAACTTGACCCCGTGATTGGGCGTGATGAAGAAATTCG
TCGTGCCATTCAAGTATTACAACGCCGTACCAAAAACAACCCAGTGTTAATCGGTGAACCGGGCGTGGGGAAAACTGCGA
TTGTCGAAGGGCTGGCGCAACGCATTGTTAATGGTGAAGTACCCGAAGGCTTGAAAAATAAGCGCGTTCTGTCTTTAGAT
ATGGGGGCATTGATTGCCGGTGCAAAATACCGTGGTGAATTTGAAGAACGTTTAAAAGCGGTGTTAAATGAACTGTCAAA
AGAAGAAGGACGCGTGATTCTCTTTATTGATGAAATTCACACCATGGTGGGGGCAGGGAAAACCGATGGCGCGATGGATG
CCGGTAACTTGCTCAAACCAAGCTTAGCCCGTGGGGAATTACACTGCGTGGGGGCGACAACACTAGATGAATATCGTCAA
TACATAGAGAAAGATGCCGCCCTTGAGCGTCGTTTCCAAAAAGTGTTTGTTGGTGAGCCAACGGTGGAAGATACCATTGC
GATCTTACGTGGGTTAAAAGAACGTTACGAAATCCACCACCATGTTCAAATTACTGACCCTGCGATTGTGGCGGCAGCGA
CCCTTTCTCATCGTTATGTATCTGATCGTCAGCTACCTGATAAAGCGATTGATTTAATTGATGAAGCAGCATCGAGCATT
CGTATGGAAATTGACTCTAAACCTCAGCCGTTAGATCGTTTAGAGCGCCGTATCATTCAATTAAAATTAGAGCAACAAGC
GCTACAAAAAGAAGATGATGATGCGAGTCGTAAACGTTTAGCAATGCTTGAAAAAGAATTAGGTGAAAAAGAACGTGAAT
ATGCAGAATTAGAAGATGTTTGGAAAGCTGAAAAAGCCGCCCTTTCAGGTACACAGCATATTAAAGCGGAGCTAGACAGT
GCCAAAACACAAATGGAACAAGCTCGCCGTGCCAGTGACTTCGCAAAAATGTCGGAATTACAATACGGAGTGATCCCCGC
GCTAGAAAAACAATTGGCGCAAGCAGAATCCGCTGAAGGCAAAGAAATGACTTTACTGCGCTATCGTGTGACCGACGAGG
AAATTGCCGAAGTGCTTTCGCGTGCAACTGGTATTCCTGTGGCGAAGATGATGGAAGGGGAAAAAGAAAAACTCTTACGT
ATGGAAGAAGAATTGCACAAACGAGTGATTGGTCAACATGAAGCCATTGAAGCAGTATCGAATGCAATTCGCCGTAGCCG
TGCCGGGTTATCCGATCCAAATCGTCCAATTGGATCGTTCTTGTTCTTAGGTCCAACCGGGGTCGGGAAAACAGAACTTT
GTAAAACCCTTGCCAATTTCCTGTTTGATGACGAAAACGCGATGGTGCGTATTGATATGTCAGAATTTATGGAAAAACAC
AGTGTTTCACGCTTAGTGGGCGCCCCTCCGGGTTATGTGGGTTACGAAGAAGGAGGCTATTTAACCGAAGCCGTTCGTCG
TCGCCCTTATTCCGTGATCTTGCTTGATGAAGTGGAAAAAGCACACCATGATGTGTTTAACATTTTATTACAAGTGTTAG
ATGATGGACGCTTAACTGATGGACAAGGGCGCACTGTGGATTTCCGCAATACTGTAGTAATCATGACATCTAACTTAGGC
TCACACTTGATCCAAGAAAACAGTACATTGGATTACCCAAGTATGAAAGAGTTAGTGATGTCTGTGGTGGGACAACATTT
CCGCCCAGAATTTATCAACCGTATTGATGAAACCGTCGTCTTCCACCCATTAGGTAAAGAAAACATTCGTGAGATTGCGA
CAATCCAACTTGCTCGCTTAATCAAACGTATGGAAAGCCATGGTTATCAATTACACTTCACCGATGCTTGCTTAGACTTC
ATTGGCGAAGTAGGTTACGATCCGGTGTATGGCGCACGTCCGTTAAAACGTGCAATTCAACAAGAAATTGAGAACCCGTT
GGCACAACAAATTCTGTCAGGCAAATTATTACCGAATCAATTAGTCACCATTGACTATGTTGACGGAAAAGTGATTGCCA
ATCAGTAA

Upstream 100 bases:

>100_bases
TACTCTTGAAAATGGTAAAAAGGGGCTTATTTATTCCTTGTAAATCGAAGGGATATTTGAACATTCCCTAACCCGATTTA
ATTTTTACAGGAGAGCAAAT

Downstream 100 bases:

>100_bases
ATCTGTGTTTCATCTCTCAAGCCCAATGCTGATGCGTTGGGCTTTTTTTATCAAGTGCGGTCATCTTTTACAAAGTTTCT
GTAAGGATTTCTCTCTTCCT

Product: ClpB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 855; Mature: 855

Protein sequence:

>855_residues
MNIEKFTTKFQQALQEAQSLAIGKDNQFIEPVHLLTALLNQQGGSTAPILTASGANLPLLRNELNAELSKLPQVSGSGGD
VQVSRSLVNLLNLCDKLAQQRQDKFISSELFLLAALEDKTLGDVLKKCGVKKENLQQAIEKVRGGQNVNDPNAEESRQAL
EKYTIDLTARAESGKLDPVIGRDEEIRRAIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPEGLKNKRVLSLD
MGALIAGAKYRGEFEERLKAVLNELSKEEGRVILFIDEIHTMVGAGKTDGAMDAGNLLKPSLARGELHCVGATTLDEYRQ
YIEKDAALERRFQKVFVGEPTVEDTIAILRGLKERYEIHHHVQITDPAIVAAATLSHRYVSDRQLPDKAIDLIDEAASSI
RMEIDSKPQPLDRLERRIIQLKLEQQALQKEDDDASRKRLAMLEKELGEKEREYAELEDVWKAEKAALSGTQHIKAELDS
AKTQMEQARRASDFAKMSELQYGVIPALEKQLAQAESAEGKEMTLLRYRVTDEEIAEVLSRATGIPVAKMMEGEKEKLLR
MEEELHKRVIGQHEAIEAVSNAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELCKTLANFLFDDENAMVRIDMSEFMEKH
SVSRLVGAPPGYVGYEEGGYLTEAVRRRPYSVILLDEVEKAHHDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNLG
SHLIQENSTLDYPSMKELVMSVVGQHFRPEFINRIDETVVFHPLGKENIREIATIQLARLIKRMESHGYQLHFTDACLDF
IGEVGYDPVYGARPLKRAIQQEIENPLAQQILSGKLLPNQLVTIDYVDGKVIANQ

Sequences:

>Translated_855_residues
MNIEKFTTKFQQALQEAQSLAIGKDNQFIEPVHLLTALLNQQGGSTAPILTASGANLPLLRNELNAELSKLPQVSGSGGD
VQVSRSLVNLLNLCDKLAQQRQDKFISSELFLLAALEDKTLGDVLKKCGVKKENLQQAIEKVRGGQNVNDPNAEESRQAL
EKYTIDLTARAESGKLDPVIGRDEEIRRAIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPEGLKNKRVLSLD
MGALIAGAKYRGEFEERLKAVLNELSKEEGRVILFIDEIHTMVGAGKTDGAMDAGNLLKPSLARGELHCVGATTLDEYRQ
YIEKDAALERRFQKVFVGEPTVEDTIAILRGLKERYEIHHHVQITDPAIVAAATLSHRYVSDRQLPDKAIDLIDEAASSI
RMEIDSKPQPLDRLERRIIQLKLEQQALQKEDDDASRKRLAMLEKELGEKEREYAELEDVWKAEKAALSGTQHIKAELDS
AKTQMEQARRASDFAKMSELQYGVIPALEKQLAQAESAEGKEMTLLRYRVTDEEIAEVLSRATGIPVAKMMEGEKEKLLR
MEEELHKRVIGQHEAIEAVSNAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELCKTLANFLFDDENAMVRIDMSEFMEKH
SVSRLVGAPPGYVGYEEGGYLTEAVRRRPYSVILLDEVEKAHHDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNLG
SHLIQENSTLDYPSMKELVMSVVGQHFRPEFINRIDETVVFHPLGKENIREIATIQLARLIKRMESHGYQLHFTDACLDF
IGEVGYDPVYGARPLKRAIQQEIENPLAQQILSGKLLPNQLVTIDYVDGKVIANQ
>Mature_855_residues
MNIEKFTTKFQQALQEAQSLAIGKDNQFIEPVHLLTALLNQQGGSTAPILTASGANLPLLRNELNAELSKLPQVSGSGGD
VQVSRSLVNLLNLCDKLAQQRQDKFISSELFLLAALEDKTLGDVLKKCGVKKENLQQAIEKVRGGQNVNDPNAEESRQAL
EKYTIDLTARAESGKLDPVIGRDEEIRRAIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPEGLKNKRVLSLD
MGALIAGAKYRGEFEERLKAVLNELSKEEGRVILFIDEIHTMVGAGKTDGAMDAGNLLKPSLARGELHCVGATTLDEYRQ
YIEKDAALERRFQKVFVGEPTVEDTIAILRGLKERYEIHHHVQITDPAIVAAATLSHRYVSDRQLPDKAIDLIDEAASSI
RMEIDSKPQPLDRLERRIIQLKLEQQALQKEDDDASRKRLAMLEKELGEKEREYAELEDVWKAEKAALSGTQHIKAELDS
AKTQMEQARRASDFAKMSELQYGVIPALEKQLAQAESAEGKEMTLLRYRVTDEEIAEVLSRATGIPVAKMMEGEKEKLLR
MEEELHKRVIGQHEAIEAVSNAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELCKTLANFLFDDENAMVRIDMSEFMEKH
SVSRLVGAPPGYVGYEEGGYLTEAVRRRPYSVILLDEVEKAHHDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNLG
SHLIQENSTLDYPSMKELVMSVVGQHFRPEFINRIDETVVFHPLGKENIREIATIQLARLIKRMESHGYQLHFTDACLDF
IGEVGYDPVYGARPLKRAIQQEIENPLAQQILSGKLLPNQLVTIDYVDGKVIANQ

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family

Homologues:

Organism=Homo sapiens, GI13540606, Length=309, Percent_Identity=36.5695792880259, Blast_Score=200, Evalue=4e-51,
Organism=Escherichia coli, GI1788943, Length=857, Percent_Identity=77.0128354725788, Blast_Score=1359, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=393, Percent_Identity=41.7302798982188, Blast_Score=278, Evalue=1e-75,
Organism=Saccharomyces cerevisiae, GI6320464, Length=709, Percent_Identity=53.0324400564175, Blast_Score=764, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=864, Percent_Identity=42.9398148148148, Blast_Score=690, Evalue=0.0,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): CLPB_PASMU (Q9CKC0)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_246643.1
- ProteinModelPortal:   Q9CKC0
- GeneID:   1245051
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM1704
- NMPDR:   fig|272843.1.peg.1705
- HOGENOM:   HBG413133
- OMA:   GSEYLAN
- ProtClustDB:   CLSK870580
- BioCyc:   PMUL272843:PM1704-MONOMER
- GO:   GO:0005737
- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR017730
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- Gene3D:   G3DSA:1.10.1780.10
- PRINTS:   PR00300
- SMART:   SM00382
- TIGRFAMs:   TIGR03346

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small

EC number: NA

Molecular weight: Translated: 95397; Mature: 95397

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS00870 CLPAB_1; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIEKFTTKFQQALQEAQSLAIGKDNQFIEPVHLLTALLNQQGGSTAPILTASGANLPLL
CCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHH
RNELNAELSKLPQVSGSGGDVQVSRSLVNLLNLCDKLAQQRQDKFISSELFLLAALEDKT
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCH
LGDVLKKCGVKKENLQQAIEKVRGGQNVNDPNAEESRQALEKYTIDLTARAESGKLDPVI
HHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHEEEEEECCCCCCCCCC
GRDEEIRRAIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPEGLKNKRVLSLD
CCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEE
MGALIAGAKYRGEFEERLKAVLNELSKEEGRVILFIDEIHTMVGAGKTDGAMDAGNLLKP
HHHHHHCCHHCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCCCCCCCC
SLARGELHCVGATTLDEYRQYIEKDAALERRFQKVFVGEPTVEDTIAILRGLKERYEIHH
CCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
HVQITDPAIVAAATLSHRYVSDRQLPDKAIDLIDEAASSIRMEIDSKPQPLDRLERRIIQ
EEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHH
LKLEQQALQKEDDDASRKRLAMLEKELGEKEREYAELEDVWKAEKAALSGTQHIKAELDS
HHHHHHHHCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
AKTQMEQARRASDFAKMSELQYGVIPALEKQLAQAESAEGKEMTLLRYRVTDEEIAEVLS
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHH
RATGIPVAKMMEGEKEKLLRMEEELHKRVIGQHEAIEAVSNAIRRSRAGLSDPNRPIGSF
HHCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCE
LFLGPTGVGKTELCKTLANFLFDDENAMVRIDMSEFMEKHSVSRLVGAPPGYVGYEEGGY
EEECCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCH
LTEAVRRRPYSVILLDEVEKAHHDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNLG
HHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEEECCHH
SHLIQENSTLDYPSMKELVMSVVGQHFRPEFINRIDETVVFHPLGKENIREIATIQLARL
HHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHH
IKRMESHGYQLHFTDACLDFIGEVGYDPVYGARPLKRAIQQEIENPLAQQILSGKLLPNQ
HHHHHHCCCEEEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
LVTIDYVDGKVIANQ
EEEEEEECCEEECCC
>Mature Secondary Structure
MNIEKFTTKFQQALQEAQSLAIGKDNQFIEPVHLLTALLNQQGGSTAPILTASGANLPLL
CCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHH
RNELNAELSKLPQVSGSGGDVQVSRSLVNLLNLCDKLAQQRQDKFISSELFLLAALEDKT
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCH
LGDVLKKCGVKKENLQQAIEKVRGGQNVNDPNAEESRQALEKYTIDLTARAESGKLDPVI
HHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHEEEEEECCCCCCCCCC
GRDEEIRRAIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPEGLKNKRVLSLD
CCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEE
MGALIAGAKYRGEFEERLKAVLNELSKEEGRVILFIDEIHTMVGAGKTDGAMDAGNLLKP
HHHHHHCCHHCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCCCCCCCC
SLARGELHCVGATTLDEYRQYIEKDAALERRFQKVFVGEPTVEDTIAILRGLKERYEIHH
CCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
HVQITDPAIVAAATLSHRYVSDRQLPDKAIDLIDEAASSIRMEIDSKPQPLDRLERRIIQ
EEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHH
LKLEQQALQKEDDDASRKRLAMLEKELGEKEREYAELEDVWKAEKAALSGTQHIKAELDS
HHHHHHHHCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
AKTQMEQARRASDFAKMSELQYGVIPALEKQLAQAESAEGKEMTLLRYRVTDEEIAEVLS
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHH
RATGIPVAKMMEGEKEKLLRMEEELHKRVIGQHEAIEAVSNAIRRSRAGLSDPNRPIGSF
HHCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCE
LFLGPTGVGKTELCKTLANFLFDDENAMVRIDMSEFMEKHSVSRLVGAPPGYVGYEEGGY
EEECCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCH
LTEAVRRRPYSVILLDEVEKAHHDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNLG
HHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEEECCHH
SHLIQENSTLDYPSMKELVMSVVGQHFRPEFINRIDETVVFHPLGKENIREIATIQLARL
HHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHH
IKRMESHGYQLHFTDACLDFIGEVGYDPVYGARPLKRAIQQEIENPLAQQILSGKLLPNQ
HHHHHHCCCEEEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
LVTIDYVDGKVIANQ
EEEEEEECCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11248100