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The map label for this gene is xerC

Identifier: 15603566

GI number: 15603566

Start: 1907534

End: 1908421

Strand: Reverse

Name: xerC

Synonym: PM1701

Alternate gene names: 15603566

Gene position: 1908421-1907534 (Counterclockwise)

Preceding gene: 15603567

Following gene: 15603565

Centisome position: 84.54

GC content: 41.22

Gene sequence:

>888_bases
ATGCAAGAACAGTTAGACAAATATTGGAATTATCTGCGCATTGAAAGACAAGTAAGCCCGCATACGTTGACGAATTACCA
GCGTCAGCTTTATCGCATTGTGGACATTCTGGCGGAAAATGGGATCACAAGTTGGCAAGCCGTGACACCCAGTATTGTGC
GTTTTATTTTGGCGCAAAGTAATAAAGATGGTTTAAAAGAACGCAGTTTAGCATTGCGTTTGTCGGTATTACGCCGTTTT
TTTACCTATTTAGTCCAACAACAAGATATTAACGTCAATCCCGCTACTGGCGTGTCTGCCCCAAAACAAAATCGACACTT
ACCGAAGAATATTGACGCTGAACAAGTACAGCAATTACTGAACAACGATAGCAAGGAACCAATTGATATTCGGGATCGAG
CGATTTTAGAGTTGTTATACAGTTCCGGTTTACGTTTATCCGAATTACAAAGTTTGAATTTAAACAGCATTAATACTCGA
GTACGAGAAGTGCGGGTGATGGGTAAAGGTAATAAAGAACGTATTGTGCCTTTCGGGCGTTATGCCTCTCATGCAATTCA
ACAGTGGTTGAAAGTGCGTATCTTGTTTAACCCAAAAGATGAAGCGCTGTTTGTCAGCCAATTAGGCAATCGCCTTACTC
ACAGAGCTATTCAACAACGGCTCGAAGTTTGGGGAATTAAACAAGGACTAAGCAGTCATTTAAATCCACATAAACTGCGT
CATTCCTTTGCCACACATATGCTCGAGGCGAGCTCTGATTTACGCGCGGTACAAGAATTATTAGGTCACAGTAATTTATC
CACCACTCAAATTTATACCCATTTAAATTTTCAACATCTTGCGGAGGTGTATGATTCAGCACATCCGCGTGCGAAACGCA
AAAAATAG

Upstream 100 bases:

>100_bases
TAGTGGATATTGTCACCTTACATTTGGGACGATGGGTGGACAGTTTTAAAAAAGCCTAAGTTGGCTTGTGTTAAAAAATA
AGTGGGTAACGGGGAGTGAA

Downstream 100 bases:

>100_bases
GAAAATTGTATGAAATTCTACCGCACTTTACGCCCTTTCAAATTAATCAGTTTTGATTTGGACGACACCCTGTACGATAA
CAGCGACGTGATTCGCCTCG

Product: site-specific tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MQEQLDKYWNYLRIERQVSPHTLTNYQRQLYRIVDILAENGITSWQAVTPSIVRFILAQSNKDGLKERSLALRLSVLRRF
FTYLVQQQDINVNPATGVSAPKQNRHLPKNIDAEQVQQLLNNDSKEPIDIRDRAILELLYSSGLRLSELQSLNLNSINTR
VREVRVMGKGNKERIVPFGRYASHAIQQWLKVRILFNPKDEALFVSQLGNRLTHRAIQQRLEVWGIKQGLSSHLNPHKLR
HSFATHMLEASSDLRAVQELLGHSNLSTTQIYTHLNFQHLAEVYDSAHPRAKRKK

Sequences:

>Translated_295_residues
MQEQLDKYWNYLRIERQVSPHTLTNYQRQLYRIVDILAENGITSWQAVTPSIVRFILAQSNKDGLKERSLALRLSVLRRF
FTYLVQQQDINVNPATGVSAPKQNRHLPKNIDAEQVQQLLNNDSKEPIDIRDRAILELLYSSGLRLSELQSLNLNSINTR
VREVRVMGKGNKERIVPFGRYASHAIQQWLKVRILFNPKDEALFVSQLGNRLTHRAIQQRLEVWGIKQGLSSHLNPHKLR
HSFATHMLEASSDLRAVQELLGHSNLSTTQIYTHLNFQHLAEVYDSAHPRAKRKK
>Mature_295_residues
MQEQLDKYWNYLRIERQVSPHTLTNYQRQLYRIVDILAENGITSWQAVTPSIVRFILAQSNKDGLKERSLALRLSVLRRF
FTYLVQQQDINVNPATGVSAPKQNRHLPKNIDAEQVQQLLNNDSKEPIDIRDRAILELLYSSGLRLSELQSLNLNSINTR
VREVRVMGKGNKERIVPFGRYASHAIQQWLKVRILFNPKDEALFVSQLGNRLTHRAIQQRLEVWGIKQGLSSHLNPHKLR
HSFATHMLEASSDLRAVQELLGHSNLSTTQIYTHLNFQHLAEVYDSAHPRAKRKK

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4973

COG function: function code L; Site-specific recombinase XerC

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily

Homologues:

Organism=Escherichia coli, GI1790244, Length=295, Percent_Identity=57.2881355932203, Blast_Score=355, Evalue=2e-99,
Organism=Escherichia coli, GI1789261, Length=293, Percent_Identity=37.8839590443686, Blast_Score=192, Evalue=1e-50,
Organism=Escherichia coli, GI1790768, Length=182, Percent_Identity=26.9230769230769, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1790767, Length=180, Percent_Identity=26.6666666666667, Blast_Score=71, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XERC_PASMU (Q9CKC2)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_246640.1
- ProteinModelPortal:   Q9CKC2
- SMR:   Q9CKC2
- GeneID:   1245048
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM1701
- NMPDR:   fig|272843.1.peg.1702
- HOGENOM:   HBG727654
- OMA:   TTEGIRD
- ProtClustDB:   PRK00236
- BioCyc:   PMUL272843:PM1701-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01808
- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931
- Gene3D:   G3DSA:1.10.150.130
- Gene3D:   G3DSA:1.10.443.10
- TIGRFAMs:   TIGR02224

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase; SSF56349 DNA_brk_join_enz; SSF47823 L_intgrse_like_N

EC number: NA

Molecular weight: Translated: 34207; Mature: 34207

Theoretical pI: Translated: 10.68; Mature: 10.68

Prosite motif: NA

Important sites: ACT_SITE 145-145 ACT_SITE 169-169 ACT_SITE 237-237 ACT_SITE 240-240 ACT_SITE 263-263 ACT_SITE 272-272

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEQLDKYWNYLRIERQVSPHTLTNYQRQLYRIVDILAENGITSWQAVTPSIVRFILAQS
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCC
NKDGLKERSLALRLSVLRRFFTYLVQQQDINVNPATGVSAPKQNRHLPKNIDAEQVQQLL
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
NNDSKEPIDIRDRAILELLYSSGLRLSELQSLNLNSINTRVREVRVMGKGNKERIVPFGR
CCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCHH
YASHAIQQWLKVRILFNPKDEALFVSQLGNRLTHRAIQQRLEVWGIKQGLSSHLNPHKLR
HHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
HSFATHMLEASSDLRAVQELLGHSNLSTTQIYTHLNFQHLAEVYDSAHPRAKRKK
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MQEQLDKYWNYLRIERQVSPHTLTNYQRQLYRIVDILAENGITSWQAVTPSIVRFILAQS
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCC
NKDGLKERSLALRLSVLRRFFTYLVQQQDINVNPATGVSAPKQNRHLPKNIDAEQVQQLL
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
NNDSKEPIDIRDRAILELLYSSGLRLSELQSLNLNSINTRVREVRVMGKGNKERIVPFGR
CCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCHH
YASHAIQQWLKVRILFNPKDEALFVSQLGNRLTHRAIQQRLEVWGIKQGLSSHLNPHKLR
HHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
HSFATHMLEASSDLRAVQELLGHSNLSTTQIYTHLNFQHLAEVYDSAHPRAKRKK
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100