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The map label for this gene is folB [H]

Identifier: 15603562

GI number: 15603562

Start: 1905089

End: 1905445

Strand: Direct

Name: folB [H]

Synonym: PM1697

Alternate gene names: 15603562

Gene position: 1905089-1905445 (Clockwise)

Preceding gene: 15603560

Following gene: 15603563

Centisome position: 84.39

GC content: 41.18

Gene sequence:

>357_bases
ATGATTGATCACATTTTCATTGAGGAACTGACCGTTTTCGCTCAAATTGGGGTATATGACTGGGAACAGCAAATTAAACA
AAAATTAGTGTTTGATCTGGAAATGGCATGGGATTGCCGTCAAGCGGCAGAAACTGACGATGTGCAATATTGTTTAAATT
ATGCTGAAGTGAGTGCGTTTATTCTTGATTATGTGCAATCAAAACCCTTCTTATTGATTGAACGCGTGGCATATGAAGTG
GCGGAGCAATTACAACAACGCTTTGGCATCCGCTGGTTACGTTTAAAATTGAGTAAACCGAAAGCCGTGGCACAAGCACG
TAATGTCGGCATCATTATTGAGCGCGGAATACGATGA

Upstream 100 bases:

>100_bases
GTCCTTTAGAGTGGTCGGCATGGAAAAATTTTATTCGTCTATTGTACATAAAGTTGATAGCATAAGCCTAATGAAATTTC
ATATTGGAAGGAATAAATGA

Downstream 100 bases:

>100_bases
CGAACAAACAAGGTTATGGCTATTTTTGCTTACTGTTAGCCACCTTCTTTTGGGGCGGTAACTACCTATTTGGCAAAATA
CTCAGCACGGACATTCCACC

Product: hypothetical protein

Products: NA

Alternate protein names: DHNA [H]

Number of amino acids: Translated: 118; Mature: 118

Protein sequence:

>118_residues
MIDHIFIEELTVFAQIGVYDWEQQIKQKLVFDLEMAWDCRQAAETDDVQYCLNYAEVSAFILDYVQSKPFLLIERVAYEV
AEQLQQRFGIRWLRLKLSKPKAVAQARNVGIIIERGIR

Sequences:

>Translated_118_residues
MIDHIFIEELTVFAQIGVYDWEQQIKQKLVFDLEMAWDCRQAAETDDVQYCLNYAEVSAFILDYVQSKPFLLIERVAYEV
AEQLQQRFGIRWLRLKLSKPKAVAQARNVGIIIERGIR
>Mature_118_residues
MIDHIFIEELTVFAQIGVYDWEQQIKQKLVFDLEMAWDCRQAAETDDVQYCLNYAEVSAFILDYVQSKPFLLIERVAYEV
AEQLQQRFGIRWLRLKLSKPKAVAQARNVGIIIERGIR

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin [H]

COG id: COG1539

COG function: function code H; Dihydroneopterin aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHNA family [H]

Homologues:

Organism=Escherichia coli, GI87082204, Length=115, Percent_Identity=60, Blast_Score=147, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006156
- InterPro:   IPR006157 [H]

Pfam domain/function: PF02152 FolB [H]

EC number: =4.1.2.25 [H]

Molecular weight: Translated: 13896; Mature: 13896

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDHIFIEELTVFAQIGVYDWEQQIKQKLVFDLEMAWDCRQAAETDDVQYCLNYAEVSAF
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
ILDYVQSKPFLLIERVAYEVAEQLQQRFGIRWLRLKLSKPKAVAQARNVGIIIERGIR
HHHHHCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHCCCCEEEECCCC
>Mature Secondary Structure
MIDHIFIEELTVFAQIGVYDWEQQIKQKLVFDLEMAWDCRQAAETDDVQYCLNYAEVSAF
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
ILDYVQSKPFLLIERVAYEVAEQLQQRFGIRWLRLKLSKPKAVAQARNVGIIIERGIR
HHHHHCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHCCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]