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The map label for this gene is ytfL [C]

Identifier: 15603542

GI number: 15603542

Start: 1883439

End: 1884788

Strand: Direct

Name: ytfL [C]

Synonym: PM1677

Alternate gene names: 15603542

Gene position: 1883439-1884788 (Clockwise)

Preceding gene: 15603541

Following gene: 15603543

Centisome position: 83.43

GC content: 41.04

Gene sequence:

>1350_bases
TTGTTTCTTCCTAGCCTCCCTTACCGTTCAAAACAGAGATATTTTATGAGTTTATTTGAAGCAATTCTAAGTTTAGGCAT
ACTGATCATTATCAGTGCGGTGATTTCAGCCGCTGAAATGTCACTCGCCGGTGCGCGAAAAATCAAACTACAAAGTTTAG
TCAACGACGGTGATGCACGCGCGCAATTAGTACTTGAGCTACAAAGCCAACCCGGGCGCTTTATTACTGTTGTCCAAATT
GGCTTAAATATGGTCGCCATTTTAGGCGGAATTATTGGCGAAAGTGCGATTCGCCCCTACTTAGCCCTCGTCTTAACCCA
ACACGTCAGTGTCGAATGGCTAGATAGCGCCGCCTCTTGGTTGGCATTCGCTTTAGTCACAACCTTATTTGTGCTGCTTG
CGGATCTCGTGCCTAAACGTTTAGCGATGATTAATCCTGAAAAAGTGGCACTGCGTACTGTACGTATTATGTCTGTCTGT
ATTTTCTTACTCAAACCCTTGGTGATGATTTTTGATTCTATTGCCAATGGCTTTTTTAAGCTCTTTAGAATTTCGACCAT
ACGTGAAGAAAATATGACCCCAGAAGATATCGTCGCGATTGTCGGGGCAGGAGCGGAAGCTGGGGTTGTTAATGCACAAG
AACATTATTTGATCGAAAATATTTTTGAGATGCAACAACGCACAGTCACTTCAACGATGACAACGCGTGAAAATATTGTG
TTTTTAGACCGCTCTTTTGATCGCCAAGCCGTGCTAGATACCCTCACACACAATTCGCATTCTAAATTATTAATTTGTGA
TAACGGCTTAGATCGCATTCTCGGTTATGTAGAATCGCACACATTACTGACAATGTATCTCCAAGTTGAAAAAGGGGTCT
CATTAACAGACAGTCGTCTTTTACGTAAAGCCCTATTTATTCCAGATACGCTCTCGTTATTTGAAGTGCTTGAATTATTC
AAATCGACAGGGGAAGATTTTGCTGTGATTGTTAATGAGTACGCACTGGTGGTCGGGATTATTACTTTAAATGATGTGAT
GAGCATTGTTATGGGTGAATTAGTGTCAAATGAAGAAGAACAAATCGTGCGCCGTGATGAAGACTCTTGGTTGATTGATG
GTGCAACGCCCTTGGAAGATGTTATGCGCGCCCTCAATTTAAGTCATTTTCCGGGCGAAGAAAATTACGAAACAATCGGT
GGCTTTATGATGTATATGCTGCGTAAGATTCCGAAAAAAACCGATTTTGTATTGTATGACAAATACAAATTTGAAATTAT
TGATACCGAAAATGTGAAAATTGACCAACTGTTAGTTTCTCTCAGAAAGGACATTGACCCTACCGTTTAA

Upstream 100 bases:

>100_bases
TACGCTTTTCTTTTCAGTCCAATTCATTCGTGGCTGGTTTGATAGCGAAAACTAGCGCCTCTTTTCTCTCACGTGGTTTA
ATCTCACATTAAGCCACGTT

Downstream 100 bases:

>100_bases
ATGCTCACATTCCCACTGCAACAAAAACAAATAGATCATAATTCTTATCCGGTCTAAGTGTTTTGTTGCAGTACTCAGGG
CGAAAGGCGTAGATTCGCGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MFLPSLPYRSKQRYFMSLFEAILSLGILIIISAVISAAEMSLAGARKIKLQSLVNDGDARAQLVLELQSQPGRFITVVQI
GLNMVAILGGIIGESAIRPYLALVLTQHVSVEWLDSAASWLAFALVTTLFVLLADLVPKRLAMINPEKVALRTVRIMSVC
IFLLKPLVMIFDSIANGFFKLFRISTIREENMTPEDIVAIVGAGAEAGVVNAQEHYLIENIFEMQQRTVTSTMTTRENIV
FLDRSFDRQAVLDTLTHNSHSKLLICDNGLDRILGYVESHTLLTMYLQVEKGVSLTDSRLLRKALFIPDTLSLFEVLELF
KSTGEDFAVIVNEYALVVGIITLNDVMSIVMGELVSNEEEQIVRRDEDSWLIDGATPLEDVMRALNLSHFPGEENYETIG
GFMMYMLRKIPKKTDFVLYDKYKFEIIDTENVKIDQLLVSLRKDIDPTV

Sequences:

>Translated_449_residues
MFLPSLPYRSKQRYFMSLFEAILSLGILIIISAVISAAEMSLAGARKIKLQSLVNDGDARAQLVLELQSQPGRFITVVQI
GLNMVAILGGIIGESAIRPYLALVLTQHVSVEWLDSAASWLAFALVTTLFVLLADLVPKRLAMINPEKVALRTVRIMSVC
IFLLKPLVMIFDSIANGFFKLFRISTIREENMTPEDIVAIVGAGAEAGVVNAQEHYLIENIFEMQQRTVTSTMTTRENIV
FLDRSFDRQAVLDTLTHNSHSKLLICDNGLDRILGYVESHTLLTMYLQVEKGVSLTDSRLLRKALFIPDTLSLFEVLELF
KSTGEDFAVIVNEYALVVGIITLNDVMSIVMGELVSNEEEQIVRRDEDSWLIDGATPLEDVMRALNLSHFPGEENYETIG
GFMMYMLRKIPKKTDFVLYDKYKFEIIDTENVKIDQLLVSLRKDIDPTV
>Mature_449_residues
MFLPSLPYRSKQRYFMSLFEAILSLGILIIISAVISAAEMSLAGARKIKLQSLVNDGDARAQLVLELQSQPGRFITVVQI
GLNMVAILGGIIGESAIRPYLALVLTQHVSVEWLDSAASWLAFALVTTLFVLLADLVPKRLAMINPEKVALRTVRIMSVC
IFLLKPLVMIFDSIANGFFKLFRISTIREENMTPEDIVAIVGAGAEAGVVNAQEHYLIENIFEMQQRTVTSTMTTRENIV
FLDRSFDRQAVLDTLTHNSHSKLLICDNGLDRILGYVESHTLLTMYLQVEKGVSLTDSRLLRKALFIPDTLSLFEVLELF
KSTGEDFAVIVNEYALVVGIITLNDVMSIVMGELVSNEEEQIVRRDEDSWLIDGATPLEDVMRALNLSHFPGEENYETIG
GFMMYMLRKIPKKTDFVLYDKYKFEIIDTENVKIDQLLVSLRKDIDPTV

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=390, Percent_Identity=23.0769230769231, Blast_Score=123, Evalue=4e-28,
Organism=Escherichia coli, GI1790664, Length=424, Percent_Identity=51.6509433962264, Blast_Score=449, Evalue=1e-127,
Organism=Escherichia coli, GI145693175, Length=416, Percent_Identity=23.3173076923077, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI87082033, Length=243, Percent_Identity=32.5102880658436, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1788119, Length=228, Percent_Identity=25.4385964912281, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1786879, Length=282, Percent_Identity=22.3404255319149, Blast_Score=89, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 50453; Mature: 50453

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLPSLPYRSKQRYFMSLFEAILSLGILIIISAVISAAEMSLAGARKIKLQSLVNDGDAR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
AQLVLELQSQPGRFITVVQIGLNMVAILGGIIGESAIRPYLALVLTQHVSVEWLDSAASW
HHEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LAFALVTTLFVLLADLVPKRLAMINPEKVALRTVRIMSVCIFLLKPLVMIFDSIANGFFK
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFRISTIREENMTPEDIVAIVGAGAEAGVVNAQEHYLIENIFEMQQRTVTSTMTTRENIV
HHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEE
FLDRSFDRQAVLDTLTHNSHSKLLICDNGLDRILGYVESHTLLTMYLQVEKGVSLTDSRL
EEECCCCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHCCHHEEEEEEHHCCCCCHHHHH
LRKALFIPDTLSLFEVLELFKSTGEDFAVIVNEYALVVGIITLNDVMSIVMGELVSNEEE
HHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
QIVRRDEDSWLIDGATPLEDVMRALNLSHFPGEENYETIGGFMMYMLRKIPKKTDFVLYD
HHHHCCCCCEEECCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEE
KYKFEIIDTENVKIDQLLVSLRKDIDPTV
EEEEEEECCCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MFLPSLPYRSKQRYFMSLFEAILSLGILIIISAVISAAEMSLAGARKIKLQSLVNDGDAR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
AQLVLELQSQPGRFITVVQIGLNMVAILGGIIGESAIRPYLALVLTQHVSVEWLDSAASW
HHEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LAFALVTTLFVLLADLVPKRLAMINPEKVALRTVRIMSVCIFLLKPLVMIFDSIANGFFK
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFRISTIREENMTPEDIVAIVGAGAEAGVVNAQEHYLIENIFEMQQRTVTSTMTTRENIV
HHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEE
FLDRSFDRQAVLDTLTHNSHSKLLICDNGLDRILGYVESHTLLTMYLQVEKGVSLTDSRL
EEECCCCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHCCHHEEEEEEHHCCCCCHHHHH
LRKALFIPDTLSLFEVLELFKSTGEDFAVIVNEYALVVGIITLNDVMSIVMGELVSNEEE
HHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
QIVRRDEDSWLIDGATPLEDVMRALNLSHFPGEENYETIGGFMMYMLRKIPKKTDFVLYD
HHHHCCCCCEEECCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEE
KYKFEIIDTENVKIDQLLVSLRKDIDPTV
EEEEEEECCCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]