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The map label for this gene is yggW [C]

Identifier: 15603534

GI number: 15603534

Start: 1876025

End: 1877179

Strand: Direct

Name: yggW [C]

Synonym: PM1669

Alternate gene names: 15603534

Gene position: 1876025-1877179 (Clockwise)

Preceding gene: 15603533

Following gene: 15603535

Centisome position: 83.1

GC content: 40.61

Gene sequence:

>1155_bases
GTGAATATAAACCGCCTTCCCCCACTAAGCCTGTATATTCATATTCCTTGGTGTGTACAAAAATGCCCTTATTGTGATTT
TAATTCTCATGCACAAAAAGGACATATTCCTGAACAAGACTATATTGCCCACTTATTGCAAGATCTACATCAAGATCGGC
AACGTTTTCAAGACAGTATTCAAGATCGTTCTCTCCATTCGATTTTTATTGGGGGAGGAACACCTAGTCTATTTTCTGCG
GAAGGAATTCATACGCTCTTATCTGGCGTTGCACAATGTCTCCCTTTTCAACCCGACATTGAAATTACGCTTGAAGCTAA
TCCCGGTACAGCCGAAGCAGAACGTTTCAAAGGTTATGTCCAAGCAGGTGTCACCCGCATTTCAATGGGTATTCAAAGCT
TCAATGATGATAAATTAGTACGTTTAGGTCGCATCCATAATGCACAAGAAGCCAAAAGTGCGGTTGGTTTTGCCAAACTT
TCTGGGCTAAAAAGTTTTAATTTAGATCTGATGCACGGGCTACCTAACCAGACCTTAGAAGAAGCGCTCTCTGATTTACA
ACAAGCGATTGCACTCGAGCCTCCCCACCTTTCTTGGTATCAACTCACTATTGAACCTAATACGATGTTTGCCTATCGTC
CGCCCGTTTTGCCTGATGATGACGCACTCTGGGATATTTTTGAACAAGGTCATCAACTATTAACGGAGGCAGGTTATGTG
CAATATGAAACCTCTGCTTATGCGAAACCCGCTTTTCAATGTCGGCATAACCTGAATTATTGGCGTTTTGGTGATTATTT
AGCAATTGGTTGTGGTGCACATGGTAAAATCACACAACCAAACGGCGAAATTAAACGTTATTCAAAAACCAAACATCCAA
AAGGTTATATGCGTGGGGACTATTTGTACGAAGAAAAAACCGTTGCCACAGAAGATCTGGCTTTTGAATTTTTTATGAAC
CGTTTTCGTTTATTAGAAGCGGTCCCCAAAACAGATTTCACCCGACTCACTGGACTGTGTGAAGAAAGTATTCAGCCACA
AATTCAATGGGCATTAGCCAAAAAATATCTTGTTGAAACGGAAGTTGCATGGCAAGTGACCGAACAAGGCAAGTTATTTT
TAAATGAATTGTTAGCAGAATTTTTACCAAAATAG

Upstream 100 bases:

>100_bases
ATGCGGTTGTGGGTGTCGAAGTCAATTACACATCAATCAATGGTGAAGGCAAAAGTATGTTTATGATTGTGGCAAGTGGA
ACAGCCGTGGTGGTACGTTA

Downstream 100 bases:

>100_bases
GCTTGTTAATCCGCTTGAATAAGATTAAAGTAAGGCGTTATTACACCATGCGCAAACGATTACGCAAGTTATATATCAAT
CAAAAGATGTCGTGCTACAT

Product: coproporphyrinogen III oxidase

Products: Protoporphyrinogen IX; CO2; H2O

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MNINRLPPLSLYIHIPWCVQKCPYCDFNSHAQKGHIPEQDYIAHLLQDLHQDRQRFQDSIQDRSLHSIFIGGGTPSLFSA
EGIHTLLSGVAQCLPFQPDIEITLEANPGTAEAERFKGYVQAGVTRISMGIQSFNDDKLVRLGRIHNAQEAKSAVGFAKL
SGLKSFNLDLMHGLPNQTLEEALSDLQQAIALEPPHLSWYQLTIEPNTMFAYRPPVLPDDDALWDIFEQGHQLLTEAGYV
QYETSAYAKPAFQCRHNLNYWRFGDYLAIGCGAHGKITQPNGEIKRYSKTKHPKGYMRGDYLYEEKTVATEDLAFEFFMN
RFRLLEAVPKTDFTRLTGLCEESIQPQIQWALAKKYLVETEVAWQVTEQGKLFLNELLAEFLPK

Sequences:

>Translated_384_residues
MNINRLPPLSLYIHIPWCVQKCPYCDFNSHAQKGHIPEQDYIAHLLQDLHQDRQRFQDSIQDRSLHSIFIGGGTPSLFSA
EGIHTLLSGVAQCLPFQPDIEITLEANPGTAEAERFKGYVQAGVTRISMGIQSFNDDKLVRLGRIHNAQEAKSAVGFAKL
SGLKSFNLDLMHGLPNQTLEEALSDLQQAIALEPPHLSWYQLTIEPNTMFAYRPPVLPDDDALWDIFEQGHQLLTEAGYV
QYETSAYAKPAFQCRHNLNYWRFGDYLAIGCGAHGKITQPNGEIKRYSKTKHPKGYMRGDYLYEEKTVATEDLAFEFFMN
RFRLLEAVPKTDFTRLTGLCEESIQPQIQWALAKKYLVETEVAWQVTEQGKLFLNELLAEFLPK
>Mature_384_residues
MNINRLPPLSLYIHIPWCVQKCPYCDFNSHAQKGHIPEQDYIAHLLQDLHQDRQRFQDSIQDRSLHSIFIGGGTPSLFSA
EGIHTLLSGVAQCLPFQPDIEITLEANPGTAEAERFKGYVQAGVTRISMGIQSFNDDKLVRLGRIHNAQEAKSAVGFAKL
SGLKSFNLDLMHGLPNQTLEEALSDLQQAIALEPPHLSWYQLTIEPNTMFAYRPPVLPDDDALWDIFEQGHQLLTEAGYV
QYETSAYAKPAFQCRHNLNYWRFGDYLAIGCGAHGKITQPNGEIKRYSKTKHPKGYMRGDYLYEEKTVATEDLAFEFFMN
RFRLLEAVPKTDFTRLTGLCEESIQPQIQWALAKKYLVETEVAWQVTEQGKLFLNELLAEFLPK

Specific function: Unknown

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=305, Percent_Identity=35.7377049180328, Blast_Score=174, Evalue=1e-43,
Organism=Escherichia coli, GI1789325, Length=378, Percent_Identity=66.6666666666667, Blast_Score=533, Evalue=1e-153,
Organism=Escherichia coli, GI87082341, Length=405, Percent_Identity=26.4197530864197, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: 1.3.3.3

Molecular weight: Translated: 43724; Mature: 43724

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNINRLPPLSLYIHIPWCVQKCPYCDFNSHAQKGHIPEQDYIAHLLQDLHQDRQRFQDSI
CCCCCCCCEEEEEECCHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
QDRSLHSIFIGGGTPSLFSAEGIHTLLSGVAQCLPFQPDIEITLEANPGTAEAERFKGYV
HCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHH
QAGVTRISMGIQSFNDDKLVRLGRIHNAQEAKSAVGFAKLSGLKSFNLDLMHGLPNQTLE
HHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHH
EALSDLQQAIALEPPHLSWYQLTIEPNTMFAYRPPVLPDDDALWDIFEQGHQLLTEAGYV
HHHHHHHHHHCCCCCCCCEEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCE
QYETSAYAKPAFQCRHNLNYWRFGDYLAIGCGAHGKITQPNGEIKRYSKTKHPKGYMRGD
EEECCHHCCHHHHHHHCCCEEEECCEEEEECCCCCCEECCCCHHHHHHCCCCCCCCCCCC
YLYEEKTVATEDLAFEFFMNRFRLLEAVPKTDFTRLTGLCEESIQPQIQWALAKKYLVET
EEECCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
EVAWQVTEQGKLFLNELLAEFLPK
HHHEEEHHCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNINRLPPLSLYIHIPWCVQKCPYCDFNSHAQKGHIPEQDYIAHLLQDLHQDRQRFQDSI
CCCCCCCCEEEEEECCHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
QDRSLHSIFIGGGTPSLFSAEGIHTLLSGVAQCLPFQPDIEITLEANPGTAEAERFKGYV
HCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHH
QAGVTRISMGIQSFNDDKLVRLGRIHNAQEAKSAVGFAKLSGLKSFNLDLMHGLPNQTLE
HHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHH
EALSDLQQAIALEPPHLSWYQLTIEPNTMFAYRPPVLPDDDALWDIFEQGHQLLTEAGYV
HHHHHHHHHHCCCCCCCCEEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCE
QYETSAYAKPAFQCRHNLNYWRFGDYLAIGCGAHGKITQPNGEIKRYSKTKHPKGYMRGD
EEECCHHCCHHHHHHHCCCEEEECCEEEEECCCCCCEECCCCHHHHHHCCCCCCCCCCCC
YLYEEKTVATEDLAFEFFMNRFRLLEAVPKTDFTRLTGLCEESIQPQIQWALAKKYLVET
EEECCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
EVAWQVTEQGKLFLNELLAEFLPK
HHHEEEHHCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coproporphyrinogen III; O2; H+

Specific reaction: coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]