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The map label for this gene is asd [H]

Identifier: 15603497

GI number: 15603497

Start: 1842756

End: 1843865

Strand: Reverse

Name: asd [H]

Synonym: PM1632

Alternate gene names: 15603497

Gene position: 1843865-1842756 (Counterclockwise)

Preceding gene: 15603503

Following gene: 15603496

Centisome position: 81.68

GC content: 44.05

Gene sequence:

>1110_bases
ATGCAAAACGTTGGTTTTATCGGTTGGCGTGGGATGGTGGGGTCCGTCTTGATGGATCGTATGCAAGAAGAAAATGACTT
TGCCAATATCAATCCTGTGTTTTTTACCACATCACAAGCGGGTCAAAACGCCCCCGTATTTGGTGGCAAGCAAGCGGGTG
AGCTGAAAGATGCTTTTGATATCGCTGAATTACAAAAATTAGACATTATCGTGACCTGCCAAGGTGGTGATTATACCAAC
GAGGTGTATCCGAAATTACGTGCAGCAGGTTGGAAGGGATATTGGATTGATGCCGCGTCCGCATTACGCATGGAAAAAGA
CGCGATTATCGTGCTTGATCCAGTGAACCAAAATGTCATCAGCGAAGGCTTAAAAAATGGCATTAAAACCTACGTTGGCG
GTAACTGTACTGTGAGTTTAATGTTAATGGCGTTAGGCGGTTTATTTGAACGTGATTTAGTAGAATGGGTGTCTGTGGCA
ACATACCAAGCAGCAAGTGGTGCGGGTGCGAAAAACATGCGCGAATTATTGGTACAAATGGGTCAACTTGAAGACAGCGT
GAAAGTGGATTTAGATAATCCAGCCTCCTCCATTTTAGACATTGAACGTAAAGTAACAGCAAAAATGCGTGGTGATTTAC
CGATTGAAAACTTTGGTGCACCACTGGCAGGGAGCTTAATTCCGTGGATTGATAAACTCTGGGAAGATGGTCAAACCAAA
GAAGAATGGAAAGGCTATGCGGAAACCAATAAAATTCTTGGCTTAGACGACAGTCCAATTCCTGTTGATGGTTTATGTGT
GCGTATCGGTGCATTGCGTTGCCACAGCCAAGCGTTCACCATCAAAATGAAAAAAGATTTACCACTTGAAGAAATTGAAC
AAATTCTTGCAAGTCACAATGAATGGGTGAAAGTGATCCCAAATGAAAAAGACGTGACCTTACGTGAACTGACGCCAACC
AAAGTGACAGGAACTTTATCTGTGCCCGTTGGTCGTTTACGTAAACTCAAAATGGGACCGGAATATTTAGCCGCGTTCAC
AGTGGGCGACCAATTACTCTGGGGTGCCGCTGAGCCACTTCGCCGTATTTTAAAACAACTTGTGGCGTAA

Upstream 100 bases:

>100_bases
TTTTATAGATAAAAAGGCTTGCATTTATTGAAACGATCTTGTAATTAATTAGCTTTATTCAAACACAATATCATTCATAT
TTTTAGATAAGGAAAATTTT

Downstream 100 bases:

>100_bases
TCCCCTTTCCTATCATAAAGAGCAGGCAACACGCCTGCTTTTTTCCTTTCTACGCCTCATCCTAACTGTCTGGCACATAG
TCGGCAAACCGATTTTATGC

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MQNVGFIGWRGMVGSVLMDRMQEENDFANINPVFFTTSQAGQNAPVFGGKQAGELKDAFDIAELQKLDIIVTCQGGDYTN
EVYPKLRAAGWKGYWIDAASALRMEKDAIIVLDPVNQNVISEGLKNGIKTYVGGNCTVSLMLMALGGLFERDLVEWVSVA
TYQAASGAGAKNMRELLVQMGQLEDSVKVDLDNPASSILDIERKVTAKMRGDLPIENFGAPLAGSLIPWIDKLWEDGQTK
EEWKGYAETNKILGLDDSPIPVDGLCVRIGALRCHSQAFTIKMKKDLPLEEIEQILASHNEWVKVIPNEKDVTLRELTPT
KVTGTLSVPVGRLRKLKMGPEYLAAFTVGDQLLWGAAEPLRRILKQLVA

Sequences:

>Translated_369_residues
MQNVGFIGWRGMVGSVLMDRMQEENDFANINPVFFTTSQAGQNAPVFGGKQAGELKDAFDIAELQKLDIIVTCQGGDYTN
EVYPKLRAAGWKGYWIDAASALRMEKDAIIVLDPVNQNVISEGLKNGIKTYVGGNCTVSLMLMALGGLFERDLVEWVSVA
TYQAASGAGAKNMRELLVQMGQLEDSVKVDLDNPASSILDIERKVTAKMRGDLPIENFGAPLAGSLIPWIDKLWEDGQTK
EEWKGYAETNKILGLDDSPIPVDGLCVRIGALRCHSQAFTIKMKKDLPLEEIEQILASHNEWVKVIPNEKDVTLRELTPT
KVTGTLSVPVGRLRKLKMGPEYLAAFTVGDQLLWGAAEPLRRILKQLVA
>Mature_369_residues
MQNVGFIGWRGMVGSVLMDRMQEENDFANINPVFFTTSQAGQNAPVFGGKQAGELKDAFDIAELQKLDIIVTCQGGDYTN
EVYPKLRAAGWKGYWIDAASALRMEKDAIIVLDPVNQNVISEGLKNGIKTYVGGNCTVSLMLMALGGLFERDLVEWVSVA
TYQAASGAGAKNMRELLVQMGQLEDSVKVDLDNPASSILDIERKVTAKMRGDLPIENFGAPLAGSLIPWIDKLWEDGQTK
EEWKGYAETNKILGLDDSPIPVDGLCVRIGALRCHSQAFTIKMKKDLPLEEIEQILASHNEWVKVIPNEKDVTLRELTPT
KVTGTLSVPVGRLRKLKMGPEYLAAFTVGDQLLWGAAEPLRRILKQLVA

Specific function: Second step in the common biosynthetic pathway leading from Asp to the cell wall precursor meso-diaminopimelate, to Lys, to Met, to Ile and to Thr. [C]

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789841, Length=368, Percent_Identity=72.2826086956522, Blast_Score=562, Evalue=1e-161,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR011534
- InterPro:   IPR012080
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 40593; Mature: 40593

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS01103 ASD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNVGFIGWRGMVGSVLMDRMQEENDFANINPVFFTTSQAGQNAPVFGGKQAGELKDAFD
CCCCCCEEHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHH
IAELQKLDIIVTCQGGDYTNEVYPKLRAAGWKGYWIDAASALRMEKDAIIVLDPVNQNVI
HHHHHHEEEEEEECCCCCCHHHHHHHHHCCCCCEEECCHHHHEECCCCEEEECCCCHHHH
SEGLKNGIKTYVGGNCTVSLMLMALGGLFERDLVEWVSVATYQAASGAGAKNMRELLVQM
HHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
GQLEDSVKVDLDNPASSILDIERKVTAKMRGDLPIENFGAPLAGSLIPWIDKLWEDGQTK
HCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHCCCCCH
EEWKGYAETNKILGLDDSPIPVDGLCVRIGALRCHSQAFTIKMKKDLPLEEIEQILASHN
HHHCCHHHCCCEECCCCCCCCCCHHHHHHHHHEECCCEEEEEECCCCCHHHHHHHHHCCC
EWVKVIPNEKDVTLRELTPTKVTGTLSVPVGRLRKLKMGPEYLAAFTVGDQLLWGAAEPL
CEEEECCCCCCCEEEECCCCEEEEEEECCHHHHHHHCCCHHHHEEHHHCCHHHHCCHHHH
RRILKQLVA
HHHHHHHCC
>Mature Secondary Structure
MQNVGFIGWRGMVGSVLMDRMQEENDFANINPVFFTTSQAGQNAPVFGGKQAGELKDAFD
CCCCCCEEHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHH
IAELQKLDIIVTCQGGDYTNEVYPKLRAAGWKGYWIDAASALRMEKDAIIVLDPVNQNVI
HHHHHHEEEEEEECCCCCCHHHHHHHHHCCCCCEEECCHHHHEECCCCEEEECCCCHHHH
SEGLKNGIKTYVGGNCTVSLMLMALGGLFERDLVEWVSVATYQAASGAGAKNMRELLVQM
HHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
GQLEDSVKVDLDNPASSILDIERKVTAKMRGDLPIENFGAPLAGSLIPWIDKLWEDGQTK
HCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHCCCCCH
EEWKGYAETNKILGLDDSPIPVDGLCVRIGALRCHSQAFTIKMKKDLPLEEIEQILASHN
HHHCCHHHCCCEECCCCCCCCCCHHHHHHHHHEECCCEEEEEECCCCCHHHHHHHHHCCC
EWVKVIPNEKDVTLRELTPTKVTGTLSVPVGRLRKLKMGPEYLAAFTVGDQLLWGAAEPL
CEEEECCCCCCCEEEECCCCEEEEEEECCHHHHHHHCCCHHHHEEHHHCCHHHHCCHHHH
RRILKQLVA
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]