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The map label for this gene is pepE [C]

Identifier: 15603455

GI number: 15603455

Start: 1801010

End: 1801633

Strand: Reverse

Name: pepE [C]

Synonym: PM1590

Alternate gene names: 15603455

Gene position: 1801633-1801010 (Counterclockwise)

Preceding gene: 15603456

Following gene: 15603454

Centisome position: 79.81

GC content: 39.9

Gene sequence:

>624_bases
ATGAAGAAATTATTTTTAGCCTCTTCTTTTGCTGATGTCTTCGATCTCTTTCTTGATTTTGCGGGTAATATCCAAAATAA
AAGCATCACGTTTATTCCCACAGCGAGCAAAGTCGAAGAGGTTAAGTTTTATGTTGATGATGCAAGAAATGCCTTCTTAC
AACAAGGTGCGTTCATTGATGAACTTGATCTCTCGACAGCAAGCCTTGCCGAAATCACGGATAAATTAGCCAAAAACGAG
ATGATCTATGTCAGTGGCGGTAATACCTTCTTTTTACTGCAGGAATTAACACGCACAGGGACAGCACAGCTCATTCAACA
ACACATTCAAGCTGGCAAAATGTATATTGGCGAATCCGCAGGTGCCATGATTAGCGCGCCCAATATCGACTACGTCAAAT
ACATGGACAGCCTAGACCAAGCACCAATGTTACGTGATTTTACAGCACTTAATTTAGTCGATTTTTACGTTGTACCACAC
TATACCAATTTTCCTTTTGTCGAGGCGGCACAAAAGATCATTGACACTTATTCTACGACATTGCCGTTACAACCCATTGA
CAATCACCAAGCAATATTGGTCAATAACGAAACAAAAATCATCAGAGGAAACCATAAAGGATAA

Upstream 100 bases:

>100_bases
ACGAACGTGCTACACAACTTAATGCACATTTACGCATTGCAAACCGCCCGTCTGGGGGAACTGAAATCAAACTGACATTA
CATCAAAATAGGAATCTGAC

Downstream 100 bases:

>100_bases
CCTATGCAAAATCTCCAACCCTTTCATACTTTTTCTCTGCCCGTACAAGCACAGAAAATTATTGAAATTACCGATATTGA
GCAACTGAAACAACAATGGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MKKLFLASSFADVFDLFLDFAGNIQNKSITFIPTASKVEEVKFYVDDARNAFLQQGAFIDELDLSTASLAEITDKLAKNE
MIYVSGGNTFFLLQELTRTGTAQLIQQHIQAGKMYIGESAGAMISAPNIDYVKYMDSLDQAPMLRDFTALNLVDFYVVPH
YTNFPFVEAAQKIIDTYSTTLPLQPIDNHQAILVNNETKIIRGNHKG

Sequences:

>Translated_207_residues
MKKLFLASSFADVFDLFLDFAGNIQNKSITFIPTASKVEEVKFYVDDARNAFLQQGAFIDELDLSTASLAEITDKLAKNE
MIYVSGGNTFFLLQELTRTGTAQLIQQHIQAGKMYIGESAGAMISAPNIDYVKYMDSLDQAPMLRDFTALNLVDFYVVPH
YTNFPFVEAAQKIIDTYSTTLPLQPIDNHQAILVNNETKIIRGNHKG
>Mature_207_residues
MKKLFLASSFADVFDLFLDFAGNIQNKSITFIPTASKVEEVKFYVDDARNAFLQQGAFIDELDLSTASLAEITDKLAKNE
MIYVSGGNTFFLLQELTRTGTAQLIQQHIQAGKMYIGESAGAMISAPNIDYVKYMDSLDQAPMLRDFTALNLVDFYVVPH
YTNFPFVEAAQKIIDTYSTTLPLQPIDNHQAILVNNETKIIRGNHKG

Specific function: Hydrolyzes Dipeptides Containing N-Terminal Aspartate Residues. May Play A Role In Allowing The Cell To Use Peptide Aspartate To Spare Carbon Otherwise Required For The Synthesis Of The Aspartate Family Of Amino Acids. [C]

COG id: COG3340

COG function: function code E; Peptidase E

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S51 family

Homologues:

Organism=Escherichia coli, GI1790452, Length=141, Percent_Identity=31.9148936170213, Blast_Score=64, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1590_PASMU (Q9CKM2)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_246529.1
- ProteinModelPortal:   Q9CKM2
- SMR:   Q9CKM2
- GeneID:   1244937
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM1590
- NMPDR:   fig|272843.1.peg.1591
- HOGENOM:   HBG291289
- OMA:   NTFFLLQ
- BioCyc:   PMUL272843:PM1590-MONOMER
- GO:   GO:0006508
- InterPro:   IPR005320

Pfam domain/function: PF03575 Peptidase_S51

EC number: 3.4.13.21 [C]

Molecular weight: Translated: 23148; Mature: 23148

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: ACT_SITE 119-119 ACT_SITE 160-160

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLFLASSFADVFDLFLDFAGNIQNKSITFIPTASKVEEVKFYVDDARNAFLQQGAFID
CCCEEHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCEE
ELDLSTASLAEITDKLAKNEMIYVSGGNTFFLLQELTRTGTAQLIQQHIQAGKMYIGESA
HHCCCHHHHHHHHHHHHCCCEEEEECCCEEEEHHHHHCCCHHHHHHHHHHHCCEEECCCC
GAMISAPNIDYVKYMDSLDQAPMLRDFTALNLVDFYVVPHYTNFPFVEAAQKIIDTYSTT
CCEEECCCCHHHHHHHHHCCCCHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHHCC
LPLQPIDNHQAILVNNETKIIRGNHKG
CCCCCCCCCCEEEEECCEEEEECCCCC
>Mature Secondary Structure
MKKLFLASSFADVFDLFLDFAGNIQNKSITFIPTASKVEEVKFYVDDARNAFLQQGAFID
CCCEEHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCEE
ELDLSTASLAEITDKLAKNEMIYVSGGNTFFLLQELTRTGTAQLIQQHIQAGKMYIGESA
HHCCCHHHHHHHHHHHHCCCEEEEECCCEEEEHHHHHCCCHHHHHHHHHHHCCEEECCCC
GAMISAPNIDYVKYMDSLDQAPMLRDFTALNLVDFYVVPHYTNFPFVEAAQKIIDTYSTT
CCEEECCCCHHHHHHHHHCCCCHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHHCC
LPLQPIDNHQAILVNNETKIIRGNHKG
CCCCCCCCCCEEEEECCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100