Click here to switch to the map view.

The map label for this gene is citT [C]

Identifier: 15603450

GI number: 15603450

Start: 1795379

End: 1796785

Strand: Reverse

Name: citT [C]

Synonym: PM1585

Alternate gene names: 15603450

Gene position: 1796785-1795379 (Counterclockwise)

Preceding gene: 15603451

Following gene: 15603449

Centisome position: 79.59

GC content: 41.01

Gene sequence:

>1407_bases
ATGAAGTACTTACAAATAATAACAATGGTAAAAAGTAGGCGTTTCCTGTTTTTCTGTGTTTCTATCCTATTTGCTTTGCT
GATGACAATCTTACTTTCGGATGCCAGTTTTACGAAAGTGCAAAACTATGTACTTTTCCTGCTTTTCTTTGCGATCAGTT
TATGGGTCACTGAAGCCATTCCACCGTTTTCTGTCAGTATCTTAATTGTTGGCTTTTTAGTTTTTGTGATGGGTAAAAGT
GAAGCTTATGATGCCATTCAGTACCTACAAACATGGTCTGATAGTGTGATTTGGCTATTTTTAGGGGGATTTTTCCTCGC
TGAAGCCATGAAAAAAACCAAACTCGACCTTTTATTATTAAAAGCTGTCTTACCAAAATTTGGCAACAACCCGGTGTATG
TACTTTGGGGATTGATGTTAGTCACAGCTATCATGTCCATGCTGATGAGTAATACCGCTACGACTGCCATGATGATCGCG
ACGATCAGTCCGCTCTTTACTCGTCTAAATGAAAGTTCAAACCTCTCCAAAGCACTCCTCCTTGGTATTCCAGCCGCCGC
CTCTGTCGGTGGTATGGGGACAATTATTGGGTCAGCACCCAATGCGATTGCAGTCGGTGCACTGGAGAAATTAGGTCACC
CAATTTCCTTCTTAGAATGGATGATGGTAGGTACCCCGTTAGCTTTAATCCTATTGTTCATTTTCTGGCGTGTTTTAGTG
AAAAAATATGAGATTAATAAGACTGAAAGTTTAGATTTTAGTTTTTTACAAGAAACGCCTGCGATTCACTCCAACCGTGT
CGAATTTTTACACAAAATCATTGTATTAGTGATCTTAGCTGTCACACTTTTCTGCTGGCTGATGTCTAAATGGATTGGCA
TCCCTGTGGCAGCGGCCTCTGGTATTCCAATCGTGGGATTAACTATTACTGGTGTGCTCAGTGAAAAAGATATTCGCCAA
TTACCTTGGGATACCTTAATGCTCGTTGCCGGAGGTTTAGCACTTGGTTTAGCCATTGAAGAACAGCGTATTGCCGCACA
CTTTGTCGAGCAAATTAGTCACATTCAGGTGAGTTTTATCATGTTACTCAGCCTATTTGGTTTCATTACTGTGATTCTGT
CTAACTTCATGAGTAACACGGCAGCCACAACGATATTGATCCCAATGGGCGTTTCTTTACTGGCAATGGTTGGAGGTAAC
GATATTCACCCAATGATTTTACCGTTAGTGATTGGATTAAGCGCATCCTGCGCGTTATTCTTACCAGTATCAACACCACC
AAATGCGATTGCATTCAGTACGGGTTTAATTAAACAGTCTGAGTTCCGTTTAGGTGGGGTGATTATTGGTTTCCTGGGTC
CAATTCTCAGTATGTTGTGGATTTTAGCTATTTCTCCTCTACTCTAA

Upstream 100 bases:

>100_bases
TTGGTTTAAAATACGTACTTTCTTTGAACAAGATCAGAAAATACGTTTTTATTTTTGATTACAATCAGATCGATTTTAAT
TCTATTTTAAGAGGTCAACT

Downstream 100 bases:

>100_bases
CAAAATTTAACGGTATCCACTTAAAACTCACCGCACAAGAAAAGTTAATGTGCGGTGAGTCCTTTCATTCAAAAGCATTA
ACATGCTTTTTTCGCAGCAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MKYLQIITMVKSRRFLFFCVSILFALLMTILLSDASFTKVQNYVLFLLFFAISLWVTEAIPPFSVSILIVGFLVFVMGKS
EAYDAIQYLQTWSDSVIWLFLGGFFLAEAMKKTKLDLLLLKAVLPKFGNNPVYVLWGLMLVTAIMSMLMSNTATTAMMIA
TISPLFTRLNESSNLSKALLLGIPAAASVGGMGTIIGSAPNAIAVGALEKLGHPISFLEWMMVGTPLALILLFIFWRVLV
KKYEINKTESLDFSFLQETPAIHSNRVEFLHKIIVLVILAVTLFCWLMSKWIGIPVAAASGIPIVGLTITGVLSEKDIRQ
LPWDTLMLVAGGLALGLAIEEQRIAAHFVEQISHIQVSFIMLLSLFGFITVILSNFMSNTAATTILIPMGVSLLAMVGGN
DIHPMILPLVIGLSASCALFLPVSTPPNAIAFSTGLIKQSEFRLGGVIIGFLGPILSMLWILAISPLL

Sequences:

>Translated_468_residues
MKYLQIITMVKSRRFLFFCVSILFALLMTILLSDASFTKVQNYVLFLLFFAISLWVTEAIPPFSVSILIVGFLVFVMGKS
EAYDAIQYLQTWSDSVIWLFLGGFFLAEAMKKTKLDLLLLKAVLPKFGNNPVYVLWGLMLVTAIMSMLMSNTATTAMMIA
TISPLFTRLNESSNLSKALLLGIPAAASVGGMGTIIGSAPNAIAVGALEKLGHPISFLEWMMVGTPLALILLFIFWRVLV
KKYEINKTESLDFSFLQETPAIHSNRVEFLHKIIVLVILAVTLFCWLMSKWIGIPVAAASGIPIVGLTITGVLSEKDIRQ
LPWDTLMLVAGGLALGLAIEEQRIAAHFVEQISHIQVSFIMLLSLFGFITVILSNFMSNTAATTILIPMGVSLLAMVGGN
DIHPMILPLVIGLSASCALFLPVSTPPNAIAFSTGLIKQSEFRLGGVIIGFLGPILSMLWILAISPLL
>Mature_468_residues
MKYLQIITMVKSRRFLFFCVSILFALLMTILLSDASFTKVQNYVLFLLFFAISLWVTEAIPPFSVSILIVGFLVFVMGKS
EAYDAIQYLQTWSDSVIWLFLGGFFLAEAMKKTKLDLLLLKAVLPKFGNNPVYVLWGLMLVTAIMSMLMSNTATTAMMIA
TISPLFTRLNESSNLSKALLLGIPAAASVGGMGTIIGSAPNAIAVGALEKLGHPISFLEWMMVGTPLALILLFIFWRVLV
KKYEINKTESLDFSFLQETPAIHSNRVEFLHKIIVLVILAVTLFCWLMSKWIGIPVAAASGIPIVGLTITGVLSEKDIRQ
LPWDTLMLVAGGLALGLAIEEQRIAAHFVEQISHIQVSFIMLLSLFGFITVILSNFMSNTAATTILIPMGVSLLAMVGGN
DIHPMILPLVIGLSASCALFLPVSTPPNAIAFSTGLIKQSEFRLGGVIIGFLGPILSMLWILAISPLL

Specific function: Responsible For The Uptake Of Citrate In Exchange To The Efflux Of Succinate. Has A Relatively Broad Specificity For C(4)- Dicarboxylates And Tricarboxylates. [C]

COG id: COG0471

COG function: function code P; Di- and tricarboxylate transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SLC13A transporter (TC 2.A.47) family. NADC subfamily [H]

Homologues:

Organism=Homo sapiens, GI29171306, Length=499, Percent_Identity=25.6513026052104, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI301069349, Length=305, Percent_Identity=24.5901639344262, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI31377715, Length=335, Percent_Identity=23.8805970149254, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI58761541, Length=375, Percent_Identity=23.7333333333333, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI301069353, Length=375, Percent_Identity=23.7333333333333, Blast_Score=75, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI32565804, Length=443, Percent_Identity=26.1851015801354, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI71988385, Length=474, Percent_Identity=25.9493670886076, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71989118, Length=512, Percent_Identity=25.390625, Blast_Score=115, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6324340, Length=453, Percent_Identity=30.0220750551876, Blast_Score=140, Evalue=4e-34,
Organism=Saccharomyces cerevisiae, GI6322263, Length=443, Percent_Identity=28.8939051918736, Blast_Score=116, Evalue=9e-27,
Organism=Saccharomyces cerevisiae, GI6319885, Length=444, Percent_Identity=28.6036036036036, Blast_Score=110, Evalue=6e-25,
Organism=Drosophila melanogaster, GI281366409, Length=487, Percent_Identity=25.0513347022587, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17737623, Length=487, Percent_Identity=25.0513347022587, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24666468, Length=487, Percent_Identity=25.0513347022587, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI45551633, Length=487, Percent_Identity=25.0513347022587, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI281362116, Length=459, Percent_Identity=25.4901960784314, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI281362114, Length=458, Percent_Identity=25.3275109170306, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI281362112, Length=458, Percent_Identity=25.3275109170306, Blast_Score=83, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001898 [H]

Pfam domain/function: PF00939 Na_sulph_symp [H]

EC number: NA

Molecular weight: Translated: 51084; Mature: 51084

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYLQIITMVKSRRFLFFCVSILFALLMTILLSDASFTKVQNYVLFLLFFAISLWVTEAI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
PPFSVSILIVGFLVFVMGKSEAYDAIQYLQTWSDSVIWLFLGGFFLAEAMKKTKLDLLLL
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KAVLPKFGNNPVYVLWGLMLVTAIMSMLMSNTATTAMMIATISPLFTRLNESSNLSKALL
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
LGIPAAASVGGMGTIIGSAPNAIAVGALEKLGHPISFLEWMMVGTPLALILLFIFWRVLV
HCCCCHHCCCCCHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHH
KKYEINKTESLDFSFLQETPAIHSNRVEFLHKIIVLVILAVTLFCWLMSKWIGIPVAAAS
HHHCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCC
GIPIVGLTITGVLSEKDIRQLPWDTLMLVAGGLALGLAIEEQRIAAHFVEQISHIQVSFI
CCCEEEEEEEEHHCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLLSLFGFITVILSNFMSNTAATTILIPMGVSLLAMVGGNDIHPMILPLVIGLSASCALF
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEE
LPVSTPPNAIAFSTGLIKQSEFRLGGVIIGFLGPILSMLWILAISPLL
EECCCCCCCCEEHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKYLQIITMVKSRRFLFFCVSILFALLMTILLSDASFTKVQNYVLFLLFFAISLWVTEAI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
PPFSVSILIVGFLVFVMGKSEAYDAIQYLQTWSDSVIWLFLGGFFLAEAMKKTKLDLLLL
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KAVLPKFGNNPVYVLWGLMLVTAIMSMLMSNTATTAMMIATISPLFTRLNESSNLSKALL
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
LGIPAAASVGGMGTIIGSAPNAIAVGALEKLGHPISFLEWMMVGTPLALILLFIFWRVLV
HCCCCHHCCCCCHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHH
KKYEINKTESLDFSFLQETPAIHSNRVEFLHKIIVLVILAVTLFCWLMSKWIGIPVAAAS
HHHCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCC
GIPIVGLTITGVLSEKDIRQLPWDTLMLVAGGLALGLAIEEQRIAAHFVEQISHIQVSFI
CCCEEEEEEEEHHCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLLSLFGFITVILSNFMSNTAATTILIPMGVSLLAMVGGNDIHPMILPLVIGLSASCALF
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEE
LPVSTPPNAIAFSTGLIKQSEFRLGGVIIGFLGPILSMLWILAISPLL
EECCCCCCCCEEHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]