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The map label for this gene is hslO

Identifier: 15603412

GI number: 15603412

Start: 1749788

End: 1750654

Strand: Direct

Name: hslO

Synonym: PM1547

Alternate gene names: 15603412

Gene position: 1749788-1750654 (Clockwise)

Preceding gene: 15603411

Following gene: 15603413

Centisome position: 77.51

GC content: 42.33

Gene sequence:

>867_bases
ATGACAGACAACACAGACAATGACAAACTGTATCGCTACCTTTTCCAAGATCGCGCGGTGCGTGGTGAATGGGTACGGTT
AAACCAAACGTTTACTGATACGTTAAATACACATCAATATCCGAAAGTCATCCAAAACTTGCTCGGTGAAATGATGGTGG
CGACCAGTTTATTGACGGCGACGTTAAAATTTGAAGGGGATATTACCGTTCAAGTACAAGGTGATGGACCGTTAAAATTA
GCATTAGTTAATGGCAATCATCAGCAGCAAATTCGCGCATTAGCGCGTTTACAAGCGGATGTCAGTGATGATATGAGTTT
GGCGCAATTAGTCGGGAAAGGGGTATTAGTGATTACGATTGCACCGACAGAAGGCGAGCGTTACCAAGGCGTGATTGCGT
TAGATAAGCCAACCATTACTGCCTGTCTTGAAGATTATTTTGTGCGTTCAGAACAATTGCAAACCCAGCTTATTATTCGT
GCTGGCGAATTTGAAGGACAACCTGTGGCAGCCGGTATGTTGTTACAAATTATGCCGGACGGTTCAGGTTCTCCAGAGGA
TTTTGAACACTTAGCAACATTGGCAGCGACGGTGAAAGAGGAAGAACTATTTGGTTTAACAGCAGAAGAATTATTGTACC
GTTTATATCATGAAGAGCGTGTTGAAATTTTCCCTTCACAGCCGATCTCATTTTTCTGTGGCTGCTCACAAGAACGTTCT
GGTGCCGCATTGTTGTTGATTTCTGATGAAGAATTGGATGAAGTCTTGGCAGAGCATAACGGTACCATTGATATGCAGTG
TGAATGTTGTGGGACGCATTATTTCTTCAATAAAGCAGCAATTATGCAATTGAAAGTAGAAAAATAA

Upstream 100 bases:

>100_bases
TAGCTTTTCATCTTGATGATGTGATTTACCTACTTTTCTTATTAAAGAAAGGAATATGGGGAAGCTGTGTGCTTGCCCTT
AACCTGAATAAAGGCTTTTT

Downstream 100 bases:

>100_bases
GTCTTGGCATTATGGATTTTGTTGCAGGCTATCAAGATATTTGATAGCCTGTTTTTCCTTTGCAGCAAACGATTTTATGA
GAAAAACGCCGTCTTCTCAC

Product: Hsp33-like chaperonin

Products: NA

Alternate protein names: Heat shock protein 33 homolog; HSP33

Number of amino acids: Translated: 288; Mature: 287

Protein sequence:

>288_residues
MTDNTDNDKLYRYLFQDRAVRGEWVRLNQTFTDTLNTHQYPKVIQNLLGEMMVATSLLTATLKFEGDITVQVQGDGPLKL
ALVNGNHQQQIRALARLQADVSDDMSLAQLVGKGVLVITIAPTEGERYQGVIALDKPTITACLEDYFVRSEQLQTQLIIR
AGEFEGQPVAAGMLLQIMPDGSGSPEDFEHLATLAATVKEEELFGLTAEELLYRLYHEERVEIFPSQPISFFCGCSQERS
GAALLLISDEELDEVLAEHNGTIDMQCECCGTHYFFNKAAIMQLKVEK

Sequences:

>Translated_288_residues
MTDNTDNDKLYRYLFQDRAVRGEWVRLNQTFTDTLNTHQYPKVIQNLLGEMMVATSLLTATLKFEGDITVQVQGDGPLKL
ALVNGNHQQQIRALARLQADVSDDMSLAQLVGKGVLVITIAPTEGERYQGVIALDKPTITACLEDYFVRSEQLQTQLIIR
AGEFEGQPVAAGMLLQIMPDGSGSPEDFEHLATLAATVKEEELFGLTAEELLYRLYHEERVEIFPSQPISFFCGCSQERS
GAALLLISDEELDEVLAEHNGTIDMQCECCGTHYFFNKAAIMQLKVEK
>Mature_287_residues
TDNTDNDKLYRYLFQDRAVRGEWVRLNQTFTDTLNTHQYPKVIQNLLGEMMVATSLLTATLKFEGDITVQVQGDGPLKLA
LVNGNHQQQIRALARLQADVSDDMSLAQLVGKGVLVITIAPTEGERYQGVIALDKPTITACLEDYFVRSEQLQTQLIIRA
GEFEGQPVAAGMLLQIMPDGSGSPEDFEHLATLAATVKEEELFGLTAEELLYRLYHEERVEIFPSQPISFFCGCSQERSG
AALLLISDEELDEVLAEHNGTIDMQCECCGTHYFFNKAAIMQLKVEK

Specific function: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress

COG id: COG1281

COG function: function code O; Disulfide bond chaperones of the HSP33 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HSP33 family

Homologues:

Organism=Escherichia coli, GI87082260, Length=279, Percent_Identity=54.4802867383513, Blast_Score=330, Evalue=6e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSLO_PASMU (Q9CKQ9)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_246486.1
- ProteinModelPortal:   Q9CKQ9
- SMR:   Q9CKQ9
- GeneID:   1244894
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM1547
- NMPDR:   fig|272843.1.peg.1548
- HOGENOM:   HBG296531
- OMA:   AMTIDQG
- ProtClustDB:   PRK00114
- BioCyc:   PMUL272843:PM1547-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00117
- InterPro:   IPR000397
- InterPro:   IPR016154
- InterPro:   IPR016153
- InterPro:   IPR023212
- Gene3D:   G3DSA:1.10.287.480
- Gene3D:   G3DSA:3.90.1280.10
- Gene3D:   G3DSA:3.55.30.10
- PIRSF:   PIRSF005261

Pfam domain/function: PF01430 HSP33; SSF64397 Heat_shock_Hsp33_N

EC number: NA

Molecular weight: Translated: 32140; Mature: 32009

Theoretical pI: Translated: 4.30; Mature: 4.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDNTDNDKLYRYLFQDRAVRGEWVRLNQTFTDTLNTHQYPKVIQNLLGEMMVATSLLTA
CCCCCCCHHHHHHHHHHCCCCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHE
TLKFEGDITVQVQGDGPLKLALVNGNHQQQIRALARLQADVSDDMSLAQLVGKGVLVITI
EEEECCEEEEEEECCCCEEEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEEEEE
APTEGERYQGVIALDKPTITACLEDYFVRSEQLQTQLIIRAGEFEGQPVAAGMLLQIMPD
ECCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCEECCEEEEEECC
GSGSPEDFEHLATLAATVKEEELFGLTAEELLYRLYHEERVEIFPSQPISFFCGCSQERS
CCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEECCCCCCEEEECCCCCCC
GAALLLISDEELDEVLAEHNGTIDMQCECCGTHYFFNKAAIMQLKVEK
CEEEEEECCHHHHHHHHHCCCCEEEEEEEECCEEEECCEEEEEEEECC
>Mature Secondary Structure 
TDNTDNDKLYRYLFQDRAVRGEWVRLNQTFTDTLNTHQYPKVIQNLLGEMMVATSLLTA
CCCCCCHHHHHHHHHHCCCCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHE
TLKFEGDITVQVQGDGPLKLALVNGNHQQQIRALARLQADVSDDMSLAQLVGKGVLVITI
EEEECCEEEEEEECCCCEEEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEEEEE
APTEGERYQGVIALDKPTITACLEDYFVRSEQLQTQLIIRAGEFEGQPVAAGMLLQIMPD
ECCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCEECCEEEEEECC
GSGSPEDFEHLATLAATVKEEELFGLTAEELLYRLYHEERVEIFPSQPISFFCGCSQERS
CCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEECCCCCCEEEECCCCCCC
GAALLLISDEELDEVLAEHNGTIDMQCECCGTHYFFNKAAIMQLKVEK
CEEEEEECCHHHHHHHHHCCCCEEEEEEEECCEEEECCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100