Click here to switch to the map view.

The map label for this gene is cysQ [H]

Identifier: 15603413

GI number: 15603413

Start: 1750828

End: 1751655

Strand: Direct

Name: cysQ [H]

Synonym: PM1548

Alternate gene names: 15603413

Gene position: 1750828-1751655 (Clockwise)

Preceding gene: 15603412

Following gene: 15603414

Centisome position: 77.56

GC content: 41.06

Gene sequence:

>828_bases
ATGTTAGCACTTTCACCATCATTACTTGAAAAAACACTTGAAATCGCGGATCAAGCAGGGGATTTTTTAACGCGATTTTA
TACCGACTCAGGGCAAAATGCGTTAGCAATTCAAACCAAACAAGATAACACGCCAGTGACTGCCGTGGATTTATTTTTGA
GTCAATTTTTAATTGAAAAATTGACCTCACTGACACCTGAGGTCCCGATTCTTTCCGAAGAGAGTTGTAAAATCCCCTTA
CAAGATCGTGCACATTGGGCAGAATATTGGTTAATTGACCCACTCGATGGAACCCAACAATTTATTAATCGCACCGATCA
ATTTTCCATTTTGATTACACTTGTCCAACACAATCAACCCGTCTTAAGCATTACCCATGCCCCTATTTTACAAACGACCT
ATTATGCTATGCAGGGCTTTGGTGCTTACAGAAGACAGGGCAATCAACAAGAAAAGCTAAACAACCAAGCGCGACCTGAG
CAGCGAAAAATCAAAATTGCTGTGGGAGTCGGGGGCGTTGAACGGAAAATTCAGCCCTTGTTAAATCCAGCTTATCAATA
TGAATTTTTGGTTTATGGTTCAAGTGGCTTAAAAGGCGGCTTAGTAGCCGATGGCACTTGTGATTGCTATATTCGAGTAG
GAAAAACGGGTGAATGGGATACGGGGGCGGCTGAAATCCTCTTACGTGAAATGGGAGGTGCTGTGTTTGACTTTGCTTTT
CAACCGCTTAGCTATAATCAGAGAGAAAGTTTTATTAATCCCAATTTTGTGATGGTGGCGAATACAGAATTTGATTGGCA
GAAAATTTTTCAATTTCATTCGCACTAG

Upstream 100 bases:

>100_bases
TTTATGAGAAAAACGCCGTCTTCTCACACAGTAGTTTAGGTATTGCATAGCATGAAGCGGGAAACTATGTTTGGCGCTTG
TCTGTTTAAAAAGGTTATCT

Downstream 100 bases:

>100_bases
GCATTATTTATTATAAGATGCGATATCTTATGACCTCTATTTTTAACAAACGGATTTCAGGAAAAAAATGAAAATTGAAG
CAGACAACAATTGTATTGTA

Product: CysQ

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MLALSPSLLEKTLEIADQAGDFLTRFYTDSGQNALAIQTKQDNTPVTAVDLFLSQFLIEKLTSLTPEVPILSEESCKIPL
QDRAHWAEYWLIDPLDGTQQFINRTDQFSILITLVQHNQPVLSITHAPILQTTYYAMQGFGAYRRQGNQQEKLNNQARPE
QRKIKIAVGVGGVERKIQPLLNPAYQYEFLVYGSSGLKGGLVADGTCDCYIRVGKTGEWDTGAAEILLREMGGAVFDFAF
QPLSYNQRESFINPNFVMVANTEFDWQKIFQFHSH

Sequences:

>Translated_275_residues
MLALSPSLLEKTLEIADQAGDFLTRFYTDSGQNALAIQTKQDNTPVTAVDLFLSQFLIEKLTSLTPEVPILSEESCKIPL
QDRAHWAEYWLIDPLDGTQQFINRTDQFSILITLVQHNQPVLSITHAPILQTTYYAMQGFGAYRRQGNQQEKLNNQARPE
QRKIKIAVGVGGVERKIQPLLNPAYQYEFLVYGSSGLKGGLVADGTCDCYIRVGKTGEWDTGAAEILLREMGGAVFDFAF
QPLSYNQRESFINPNFVMVANTEFDWQKIFQFHSH
>Mature_275_residues
MLALSPSLLEKTLEIADQAGDFLTRFYTDSGQNALAIQTKQDNTPVTAVDLFLSQFLIEKLTSLTPEVPILSEESCKIPL
QDRAHWAEYWLIDPLDGTQQFINRTDQFSILITLVQHNQPVLSITHAPILQTTYYAMQGFGAYRRQGNQQEKLNNQARPE
QRKIKIAVGVGGVERKIQPLLNPAYQYEFLVYGSSGLKGGLVADGTCDCYIRVGKTGEWDTGAAEILLREMGGAVFDFAF
QPLSYNQRESFINPNFVMVANTEFDWQKIFQFHSH

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG1218

COG function: function code P; 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Escherichia coli, GI1790659, Length=249, Percent_Identity=34.5381526104418, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1788882, Length=235, Percent_Identity=27.6595744680851, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71995897, Length=165, Percent_Identity=26.6666666666667, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71995905, Length=165, Percent_Identity=26.6666666666667, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI193202572, Length=261, Percent_Identity=27.2030651340996, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24664918, Length=259, Percent_Identity=27.4131274131274, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24664926, Length=229, Percent_Identity=27.5109170305677, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 31033; Mature: 31033

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS00629 IMP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLALSPSLLEKTLEIADQAGDFLTRFYTDSGQNALAIQTKQDNTPVTAVDLFLSQFLIEK
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHH
LTSLTPEVPILSEESCKIPLQDRAHWAEYWLIDPLDGTQQFINRTDQFSILITLVQHNQP
HHHCCCCCCCCCCCCCCCCHHHCCCEEHEEEECCCCHHHHHHCCCCCEEEEEEEECCCCC
VLSITHAPILQTTYYAMQGFGAYRRQGNQQEKLNNQARPEQRKIKIAVGVGGVERKIQPL
EEEEECCCHHHHHHHHHHCCHHHHHCCCHHHHHCCCCCCCCCEEEEEEECCCHHHHHHHH
LNPAYQYEFLVYGSSGLKGGLVADGTCDCYIRVGKTGEWDTGAAEILLREMGGAVFDFAF
CCCCCEEEEEEECCCCCCCCEEECCCCEEEEEECCCCCCCCHHHHHHHHHHCCCEEEHCC
QPLSYNQRESFINPNFVMVANTEFDWQKIFQFHSH
CCCCCCCHHHCCCCCEEEEECCCCCHHHHHHHHCC
>Mature Secondary Structure
MLALSPSLLEKTLEIADQAGDFLTRFYTDSGQNALAIQTKQDNTPVTAVDLFLSQFLIEK
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHH
LTSLTPEVPILSEESCKIPLQDRAHWAEYWLIDPLDGTQQFINRTDQFSILITLVQHNQP
HHHCCCCCCCCCCCCCCCCHHHCCCEEHEEEECCCCHHHHHHCCCCCEEEEEEEECCCCC
VLSITHAPILQTTYYAMQGFGAYRRQGNQQEKLNNQARPEQRKIKIAVGVGGVERKIQPL
EEEEECCCHHHHHHHHHHCCHHHHHCCCHHHHHCCCCCCCCCEEEEEEECCCHHHHHHHH
LNPAYQYEFLVYGSSGLKGGLVADGTCDCYIRVGKTGEWDTGAAEILLREMGGAVFDFAF
CCCCCEEEEEEECCCCCCCCEEECCCCEEEEEECCCCCCCCHHHHHHHHHHCCCEEEHCC
QPLSYNQRESFINPNFVMVANTEFDWQKIFQFHSH
CCCCCCCHHHCCCCCEEEEECCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9020051 [H]