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The map label for this gene is hpaD [H]

Identifier: 15603396

GI number: 15603396

Start: 1730303

End: 1731148

Strand: Direct

Name: hpaD [H]

Synonym: PM1531

Alternate gene names: 15603396

Gene position: 1730303-1731148 (Clockwise)

Preceding gene: 15603395

Following gene: 15603397

Centisome position: 76.65

GC content: 44.56

Gene sequence:

>846_bases
ATGGGTAAACTCGCTTTAGCTGCCAAGATTACACATGTTCCGTCAATGTATTTGTCAGAACAACCGGGCAAACATTATGG
TTGCCGTGCTTCCGCCATTGAAGGTCACAAAGAAATTAGCCGACGTTGTCGTGATTTGGGGGTCGATACGATCATCGTAT
TTGATACACATTGGCTGGTGAATAGTGCATATCATGTGAACTGTTGTTCGCATTTTGAAGGGGTTTATACCAGTAATGAG
CTCCCACACTTTATTCGTGATATCACTTTTAATTATGAAGGCAATCCTGAATTAGGTCACATGATCGTCAAACATGCGGT
GGCGAAAGGGGTGCGCGCTCAGGCACATGAGATTGATAGCCTGAAATTGGAATACGGCACGTTGGTTCCAATGCGTTATA
TGAACGAAGATAAAGCCTTTAAAGTAATTTCCATTGCGGCATTCTGCACCTCGCATTCATTCGAAGATAGTCGCAAGCTC
GGTGAGGCGGTATTAGACGCCATTAAAGAATACGATGGCATTGTTGCCGTGTTAGCCAGCGGCTCGTTATCACACTACTT
TATTCCCGATCATTTAGCCAAAGACGGGATGAACAGCTATACCCGTGAATTTGAGCGCCAAATTGATTTGCATGTAGTGG
ATATGTGGCGTAAAGGCAATTTCAAAGACTTTTGCAAAATGTTACCGGAATACGCGGAATTCTGTCGCGGCGAGGGCAAT
ATGCACGATACAGTAATGTTGCTCGGTATGCTGGGTTGGGATAAATACGATAAGCCAGTTGAAATCTTGACGGATTTATT
CCCAAGTTCCGGTACGGGACAAATTAACGCCGTCTTCCCGGTGTAA

Upstream 100 bases:

>100_bases
ATACAGCTTTGAAGTCTTTGCTGAATTGAAAAATGTGTGCATCTCAATGCACGATCATCCAATTCCTCGCTGGGGATTAT
AAAATTAAAGGAGCAACAAT

Downstream 100 bases:

>100_bases
TCCGCACAAGTGCGGTTGGTTTCTGACACTTTTTGCTAAACAGACCGCACTTTTCTCTTCATAAAAAGGAAAATATGCAT
GCCACACTTTATTGTTGAAG

Product: HpaD

Products: NA

Alternate protein names: Homoprotocatechuate 2,3-dioxygenase; HPC dioxygenase [H]

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MGKLALAAKITHVPSMYLSEQPGKHYGCRASAIEGHKEISRRCRDLGVDTIIVFDTHWLVNSAYHVNCCSHFEGVYTSNE
LPHFIRDITFNYEGNPELGHMIVKHAVAKGVRAQAHEIDSLKLEYGTLVPMRYMNEDKAFKVISIAAFCTSHSFEDSRKL
GEAVLDAIKEYDGIVAVLASGSLSHYFIPDHLAKDGMNSYTREFERQIDLHVVDMWRKGNFKDFCKMLPEYAEFCRGEGN
MHDTVMLLGMLGWDKYDKPVEILTDLFPSSGTGQINAVFPV

Sequences:

>Translated_281_residues
MGKLALAAKITHVPSMYLSEQPGKHYGCRASAIEGHKEISRRCRDLGVDTIIVFDTHWLVNSAYHVNCCSHFEGVYTSNE
LPHFIRDITFNYEGNPELGHMIVKHAVAKGVRAQAHEIDSLKLEYGTLVPMRYMNEDKAFKVISIAAFCTSHSFEDSRKL
GEAVLDAIKEYDGIVAVLASGSLSHYFIPDHLAKDGMNSYTREFERQIDLHVVDMWRKGNFKDFCKMLPEYAEFCRGEGN
MHDTVMLLGMLGWDKYDKPVEILTDLFPSSGTGQINAVFPV
>Mature_280_residues
GKLALAAKITHVPSMYLSEQPGKHYGCRASAIEGHKEISRRCRDLGVDTIIVFDTHWLVNSAYHVNCCSHFEGVYTSNEL
PHFIRDITFNYEGNPELGHMIVKHAVAKGVRAQAHEIDSLKLEYGTLVPMRYMNEDKAFKVISIAAFCTSHSFEDSRKLG
EAVLDAIKEYDGIVAVLASGSLSHYFIPDHLAKDGMNSYTREFERQIDLHVVDMWRKGNFKDFCKMLPEYAEFCRGEGNM
HDTVMLLGMLGWDKYDKPVEILTDLFPSSGTGQINAVFPV

Specific function: Transforms homoprotocatechuic acid (HPC) into 5- carboxymethyl-2-hydroxy-muconic semialdehyde (CHMS) [H]

COG id: COG3384

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011984
- InterPro:   IPR004183 [H]

Pfam domain/function: PF02900 LigB [H]

EC number: =1.13.11.15 [H]

Molecular weight: Translated: 31716; Mature: 31584

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKLALAAKITHVPSMYLSEQPGKHYGCRASAIEGHKEISRRCRDLGVDTIIVFDTHWLV
CCCHHHHHHHHHCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECHHHH
NSAYHVNCCSHFEGVYTSNELPHFIRDITFNYEGNPELGHMIVKHAVAKGVRAQAHEIDS
CCCEEEEHHHHCCCCCCCCCCHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
LKLEYGTLVPMRYMNEDKAFKVISIAAFCTSHSFEDSRKLGEAVLDAIKEYDGIVAVLAS
EEEECCCCCCHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCEEEEEEC
GSLSHYFIPDHLAKDGMNSYTREFERQIDLHVVDMWRKGNFKDFCKMLPEYAEFCRGEGN
CCCCEEECCHHHHHCCHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCC
MHDTVMLLGMLGWDKYDKPVEILTDLFPSSGTGQINAVFPV
CHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCEEEEECC
>Mature Secondary Structure 
GKLALAAKITHVPSMYLSEQPGKHYGCRASAIEGHKEISRRCRDLGVDTIIVFDTHWLV
CCHHHHHHHHHCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECHHHH
NSAYHVNCCSHFEGVYTSNELPHFIRDITFNYEGNPELGHMIVKHAVAKGVRAQAHEIDS
CCCEEEEHHHHCCCCCCCCCCHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
LKLEYGTLVPMRYMNEDKAFKVISIAAFCTSHSFEDSRKLGEAVLDAIKEYDGIVAVLAS
EEEECCCCCCHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCEEEEEEC
GSLSHYFIPDHLAKDGMNSYTREFERQIDLHVVDMWRKGNFKDFCKMLPEYAEFCRGEGN
CCCCEEECCHHHHHCCHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCC
MHDTVMLLGMLGWDKYDKPVEILTDLFPSSGTGQINAVFPV
CHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2261999 [H]