BacMap

Definition	Pasteurella multocida subsp. multocida str. Pm70, complete genome.
Accession	NC_002663
Length	2,257,487

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The map label for this gene is hpaE [H]

Identifier: 15603395

GI number: 15603395

Start: 1728824

End: 1730284

Strand: Direct

Name: hpaE [H]

Synonym: PM1530

Alternate gene names: 15603395

Gene position: 1728824-1730284 (Clockwise)

Preceding gene: 15603394

Following gene: 15603396

Centisome position: 76.58

GC content: 44.42

Gene sequence:

>1461_bases
ATGATTAAGCATTGGATAAATGGTAAAGAAGTTGCCAGTGAAGAAACCTTTGATAATTTTAATCCTGCAACAGGTGAAGT
AATTTGTCAGGTTGCCTCTGGCGGTGAAAAAGAAATTAATGCGGCAGTTCAAGCAGCAAAAGACGCGTTCCCAAAGTGGT
CAAAAACACCAGCCAAAGAACGCGCCCGGTTGATGCGTAAGTTAGGTGAATTAATTGATCAAAATGTGGCGAAATTGGCC
GAATTGGAAACCTTAGATACGGGCTTACCCATTCATCAAACCAAAAACGTGTTGATTCCCCGTGCCTCGCATAACTTTGA
TTTCTTTGCCGAAGTTTGTACGCGTATGAATGGGCATAGCTATCCAGTCGATGACAAAATGCTCAACTATACCCTTTATC
AACCGGTTGGGGTATGTGGCTTGGTTTCCCCATGGAACGTGCCATTTATGACAGCAACCTGGAAAACCGCACCTTGTTTG
GCATTAGGCAATACTGCGGTACTTAAAATGTCCGAACTTTCACCTTTAACCGCGAATGAATTAGGGCGTTTAGCCTTGGA
GGCAGGTATTCCTGAAGGGGTTTTCAATGTGGTGCAAGGTCTCGGTTCAACAGCAGGTCATGCGTTAGTCACACACGATG
ACGTGCGTGCGATTTCATTTACCGGTGGCACGGCGACAGGTAAGCATATTTTAAAACATGCCGGTTTGAAAAAATATTCA
ATGGAGTTAGGGGGCAAATCCCCAGTGTTGATTTTTGATGATGCGGATTTAGATCGCGCCTTAGATGCGGCATTGTTCAC
CATTTTCTCGCTCAATGGCGAGCGTTGTACTGCGGGTTCACGGATTTTTATTCAAGAAACAGTGTATGACGAGTTCGTGA
AACAATTTGCAGCACGTGCAAAACGGTTAATCGTGGGCGATCCGCAAGATTTCAATACCCAAGTAGGTTCTATGATTACC
CGTCAACATTATGACAAAGTGACAGGCTATATCCGTATTGGTCTGGAAGAAGGCGCCACTTTACTTGCTGGCGGTTTAGA
ACGCCCGCAAAACTTACCAGCACATTTACAAAAAGGTCACTTTATTCAACCAACGGTCTTTGCTGATGTTGATAACCGTA
TGCGTATTGCGCAAGAGGAAATTTTTGGTCCGGTGGTGTGTTTAATGAAATTTAAAGATGAAGCAGAGGCATTACGTTTG
GCAAATGACGTGGAATACGGTCTAGCTTCTTACATTTGGACAAAAGACATTGCGAAAGCATTGCGTTTATCCAATGGCAT
TGAAGCGGGGATGGTCTTCGTCAACAGTCAAAACGTACGCGATTTACGTCAACCGTTCGGTGGCATCAAAGCCTCAGGTA
TTGGACGCGAAGGCGGCGAATACAGCTTTGAAGTCTTTGCTGAATTGAAAAATGTGTGCATCTCAATGCACGATCATCCA
ATTCCTCGCTGGGGATTATAA

Upstream 100 bases:

>100_bases
TAGAAATTGAAATTGAGCAAATTGGCAAATTGACGAACTACATTGTGAGTGAAACAGCCTTTTTTGCGCAAAACGAATAA
AGAGAAAAGGAGACAACCCT

Downstream 100 bases:

>100_bases
AATTAAAGGAGCAACAATATGGGTAAACTCGCTTTAGCTGCCAAGATTACACATGTTCCGTCAATGTATTTGTCAGAACA
ACCGGGCAAACATTATGGTT

Product: HpaE

Products: 5-carboxymethyl-2-hydroxymuconate; NADH; H+

Alternate protein names: CHMS dehydrogenase [H]

Number of amino acids: Translated: 486; Mature: 486

Protein sequence:

>486_residues
MIKHWINGKEVASEETFDNFNPATGEVICQVASGGEKEINAAVQAAKDAFPKWSKTPAKERARLMRKLGELIDQNVAKLA
ELETLDTGLPIHQTKNVLIPRASHNFDFFAEVCTRMNGHSYPVDDKMLNYTLYQPVGVCGLVSPWNVPFMTATWKTAPCL
ALGNTAVLKMSELSPLTANELGRLALEAGIPEGVFNVVQGLGSTAGHALVTHDDVRAISFTGGTATGKHILKHAGLKKYS
MELGGKSPVLIFDDADLDRALDAALFTIFSLNGERCTAGSRIFIQETVYDEFVKQFAARAKRLIVGDPQDFNTQVGSMIT
RQHYDKVTGYIRIGLEEGATLLAGGLERPQNLPAHLQKGHFIQPTVFADVDNRMRIAQEEIFGPVVCLMKFKDEAEALRL
ANDVEYGLASYIWTKDIAKALRLSNGIEAGMVFVNSQNVRDLRQPFGGIKASGIGREGGEYSFEVFAELKNVCISMHDHP
IPRWGL

Sequences:

>Translated_486_residues
MIKHWINGKEVASEETFDNFNPATGEVICQVASGGEKEINAAVQAAKDAFPKWSKTPAKERARLMRKLGELIDQNVAKLA
ELETLDTGLPIHQTKNVLIPRASHNFDFFAEVCTRMNGHSYPVDDKMLNYTLYQPVGVCGLVSPWNVPFMTATWKTAPCL
ALGNTAVLKMSELSPLTANELGRLALEAGIPEGVFNVVQGLGSTAGHALVTHDDVRAISFTGGTATGKHILKHAGLKKYS
MELGGKSPVLIFDDADLDRALDAALFTIFSLNGERCTAGSRIFIQETVYDEFVKQFAARAKRLIVGDPQDFNTQVGSMIT
RQHYDKVTGYIRIGLEEGATLLAGGLERPQNLPAHLQKGHFIQPTVFADVDNRMRIAQEEIFGPVVCLMKFKDEAEALRL
ANDVEYGLASYIWTKDIAKALRLSNGIEAGMVFVNSQNVRDLRQPFGGIKASGIGREGGEYSFEVFAELKNVCISMHDHP
IPRWGL
>Mature_486_residues
MIKHWINGKEVASEETFDNFNPATGEVICQVASGGEKEINAAVQAAKDAFPKWSKTPAKERARLMRKLGELIDQNVAKLA
ELETLDTGLPIHQTKNVLIPRASHNFDFFAEVCTRMNGHSYPVDDKMLNYTLYQPVGVCGLVSPWNVPFMTATWKTAPCL
ALGNTAVLKMSELSPLTANELGRLALEAGIPEGVFNVVQGLGSTAGHALVTHDDVRAISFTGGTATGKHILKHAGLKKYS
MELGGKSPVLIFDDADLDRALDAALFTIFSLNGERCTAGSRIFIQETVYDEFVKQFAARAKRLIVGDPQDFNTQVGSMIT
RQHYDKVTGYIRIGLEEGATLLAGGLERPQNLPAHLQKGHFIQPTVFADVDNRMRIAQEEIFGPVVCLMKFKDEAEALRL
ANDVEYGLASYIWTKDIAKALRLSNGIEAGMVFVNSQNVRDLRQPFGGIKASGIGREGGEYSFEVFAELKNVCISMHDHP
IPRWGL

Specific function: Transforms 5-carboxymethyl-2-hydroxy-muconic semialdehyde (CHMS) into 5-carboxymethyl-2-hydroxy-muconic acid (CHM) [H]

COG id: COG1012

COG function: function code C; NAD-dependent aldehyde dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI25777732, Length=473, Percent_Identity=43.9746300211416, Blast_Score=402, Evalue=1e-112,
Organism=Homo sapiens, GI12007648, Length=477, Percent_Identity=40.251572327044, Blast_Score=400, Evalue=1e-111,
Organism=Homo sapiens, GI25777724, Length=479, Percent_Identity=42.1711899791232, Blast_Score=386, Evalue=1e-107,
Organism=Homo sapiens, GI25777730, Length=474, Percent_Identity=41.5611814345992, Blast_Score=385, Evalue=1e-107,
Organism=Homo sapiens, GI153266822, Length=484, Percent_Identity=41.7355371900826, Blast_Score=383, Evalue=1e-106,
Organism=Homo sapiens, GI21361176, Length=470, Percent_Identity=41.7021276595745, Blast_Score=372, Evalue=1e-103,
Organism=Homo sapiens, GI238814322, Length=485, Percent_Identity=40, Blast_Score=363, Evalue=1e-100,
Organism=Homo sapiens, GI21614513, Length=481, Percent_Identity=41.7879417879418, Blast_Score=362, Evalue=1e-100,
Organism=Homo sapiens, GI115387104, Length=462, Percent_Identity=38.3116883116883, Blast_Score=355, Evalue=4e-98,
Organism=Homo sapiens, GI25777728, Length=422, Percent_Identity=42.8909952606635, Blast_Score=353, Evalue=2e-97,
Organism=Homo sapiens, GI25777726, Length=476, Percent_Identity=38.4453781512605, Blast_Score=332, Evalue=7e-91,
Organism=Homo sapiens, GI25952152, Length=477, Percent_Identity=36.4779874213836, Blast_Score=328, Evalue=8e-90,
Organism=Homo sapiens, GI4507229, Length=478, Percent_Identity=36.6108786610879, Blast_Score=270, Evalue=2e-72,
Organism=Homo sapiens, GI25777721, Length=491, Percent_Identity=35.4378818737271, Blast_Score=260, Evalue=3e-69,
Organism=Homo sapiens, GI301500698, Length=281, Percent_Identity=40.5693950177936, Blast_Score=240, Evalue=2e-63,
Organism=Homo sapiens, GI11095441, Length=440, Percent_Identity=29.0909090909091, Blast_Score=196, Evalue=5e-50,
Organism=Homo sapiens, GI188035924, Length=495, Percent_Identity=26.4646464646465, Blast_Score=196, Evalue=6e-50,
Organism=Homo sapiens, GI310128093, Length=479, Percent_Identity=27.1398747390397, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI310128103, Length=479, Percent_Identity=26.9311064718163, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI310128091, Length=479, Percent_Identity=25.678496868476, Blast_Score=169, Evalue=4e-42,
Organism=Homo sapiens, GI223972651, Length=462, Percent_Identity=28.5714285714286, Blast_Score=166, Evalue=6e-41,
Organism=Homo sapiens, GI310128089, Length=333, Percent_Identity=30.3303303303303, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI310128097, Length=265, Percent_Identity=31.6981132075472, Blast_Score=142, Evalue=1e-33,
Organism=Homo sapiens, GI238859541, Length=463, Percent_Identity=24.8380129589633, Blast_Score=141, Evalue=2e-33,
Organism=Homo sapiens, GI25777736, Length=461, Percent_Identity=24.7288503253796, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI25777734, Length=461, Percent_Identity=24.7288503253796, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI310128095, Length=320, Percent_Identity=28.75, Blast_Score=133, Evalue=4e-31,
Organism=Homo sapiens, GI4557303, Length=342, Percent_Identity=28.6549707602339, Blast_Score=131, Evalue=2e-30,
Organism=Homo sapiens, GI73466520, Length=342, Percent_Identity=28.6549707602339, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI223972653, Length=460, Percent_Identity=25.6521739130435, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI206597441, Length=352, Percent_Identity=29.5454545454545, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI206597439, Length=352, Percent_Identity=29.5454545454545, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI22907049, Length=352, Percent_Identity=29.5454545454545, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI71773324, Length=338, Percent_Identity=26.6272189349112, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI4502043, Length=338, Percent_Identity=26.6272189349112, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI238814371, Length=338, Percent_Identity=26.6272189349112, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI73695881, Length=351, Percent_Identity=25.0712250712251, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI73695879, Length=351, Percent_Identity=25.0712250712251, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI310128087, Length=477, Percent_Identity=22.8511530398323, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI310128099, Length=236, Percent_Identity=22.4576271186441, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI310128101, Length=236, Percent_Identity=22.4576271186441, Blast_Score=71, Evalue=3e-12,
Organism=Escherichia coli, GI1787558, Length=480, Percent_Identity=40.4166666666667, Blast_Score=347, Evalue=8e-97,
Organism=Escherichia coli, GI1789015, Length=478, Percent_Identity=37.8661087866109, Blast_Score=337, Evalue=9e-94,
Organism=Escherichia coli, GI87082295, Length=489, Percent_Identity=37.0143149284254, Blast_Score=332, Evalue=3e-92,
Organism=Escherichia coli, GI1786504, Length=467, Percent_Identity=37.9014989293362, Blast_Score=326, Evalue=2e-90,
Organism=Escherichia coli, GI87081896, Length=482, Percent_Identity=36.9294605809129, Blast_Score=317, Evalue=8e-88,
Organism=Escherichia coli, GI1787715, Length=487, Percent_Identity=36.7556468172485, Blast_Score=295, Evalue=4e-81,
Organism=Escherichia coli, GI1787684, Length=462, Percent_Identity=31.8181818181818, Blast_Score=248, Evalue=5e-67,
Organism=Escherichia coli, GI87081926, Length=456, Percent_Identity=30.0438596491228, Blast_Score=213, Evalue=3e-56,
Organism=Escherichia coli, GI1788042, Length=474, Percent_Identity=28.0590717299578, Blast_Score=174, Evalue=2e-44,
Organism=Escherichia coli, GI1787250, Length=466, Percent_Identity=25.5364806866953, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1787653, Length=301, Percent_Identity=24.5847176079734, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI25144435, Length=470, Percent_Identity=41.063829787234, Blast_Score=387, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI17562198, Length=484, Percent_Identity=40.2892561983471, Blast_Score=384, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI32564736, Length=422, Percent_Identity=40.9952606635071, Blast_Score=349, Evalue=2e-96,
Organism=Caenorhabditis elegans, GI133930964, Length=486, Percent_Identity=38.477366255144, Blast_Score=345, Evalue=3e-95,
Organism=Caenorhabditis elegans, GI17551164, Length=477, Percent_Identity=39.2033542976939, Blast_Score=330, Evalue=1e-90,
Organism=Caenorhabditis elegans, GI25143874, Length=485, Percent_Identity=35.8762886597938, Blast_Score=327, Evalue=7e-90,
Organism=Caenorhabditis elegans, GI25143876, Length=485, Percent_Identity=35.8762886597938, Blast_Score=327, Evalue=8e-90,
Organism=Caenorhabditis elegans, GI71995606, Length=485, Percent_Identity=33.4020618556701, Blast_Score=295, Evalue=5e-80,
Organism=Caenorhabditis elegans, GI17534119, Length=478, Percent_Identity=35.3556485355649, Blast_Score=275, Evalue=4e-74,
Organism=Caenorhabditis elegans, GI71995613, Length=421, Percent_Identity=33.729216152019, Blast_Score=256, Evalue=2e-68,
Organism=Caenorhabditis elegans, GI71986308, Length=440, Percent_Identity=32.2727272727273, Blast_Score=207, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI115534176, Length=502, Percent_Identity=27.0916334661355, Blast_Score=184, Evalue=9e-47,
Organism=Caenorhabditis elegans, GI25146391, Length=446, Percent_Identity=28.47533632287, Blast_Score=146, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI32566756, Length=446, Percent_Identity=28.47533632287, Blast_Score=146, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI25146394, Length=446, Percent_Identity=28.47533632287, Blast_Score=146, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI17564084, Length=450, Percent_Identity=27.7777777777778, Blast_Score=141, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI17534447, Length=501, Percent_Identity=24.750499001996, Blast_Score=131, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI32564151, Length=436, Percent_Identity=25, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI115532534, Length=432, Percent_Identity=24.7685185185185, Blast_Score=119, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI71990744, Length=313, Percent_Identity=24.9201277955272, Blast_Score=82, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6324950, Length=481, Percent_Identity=40.5405405405405, Blast_Score=363, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6320917, Length=484, Percent_Identity=40.9090909090909, Blast_Score=355, Evalue=1e-98,
Organism=Saccharomyces cerevisiae, GI6323822, Length=471, Percent_Identity=40.1273885350318, Blast_Score=339, Evalue=7e-94,
Organism=Saccharomyces cerevisiae, GI6325196, Length=481, Percent_Identity=38.2536382536383, Blast_Score=333, Evalue=3e-92,
Organism=Saccharomyces cerevisiae, GI6323821, Length=471, Percent_Identity=39.0658174097665, Blast_Score=330, Evalue=3e-91,
Organism=Saccharomyces cerevisiae, GI6319478, Length=476, Percent_Identity=33.8235294117647, Blast_Score=285, Evalue=9e-78,
Organism=Saccharomyces cerevisiae, GI6321828, Length=475, Percent_Identity=27.7894736842105, Blast_Score=164, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6321826, Length=508, Percent_Identity=25.7874015748031, Blast_Score=110, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6323757, Length=344, Percent_Identity=25.8720930232558, Blast_Score=85, Evalue=3e-17,
Organism=Drosophila melanogaster, GI20129399, Length=470, Percent_Identity=45.3191489361702, Blast_Score=408, Evalue=1e-114,
Organism=Drosophila melanogaster, GI24585660, Length=485, Percent_Identity=39.7938144329897, Blast_Score=367, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24650465, Length=487, Percent_Identity=42.5051334702259, Blast_Score=350, Evalue=2e-96,
Organism=Drosophila melanogaster, GI281362580, Length=477, Percent_Identity=36.0587002096436, Blast_Score=319, Evalue=3e-87,
Organism=Drosophila melanogaster, GI62472918, Length=477, Percent_Identity=36.0587002096436, Blast_Score=319, Evalue=3e-87,
Organism=Drosophila melanogaster, GI62472926, Length=477, Percent_Identity=36.0587002096436, Blast_Score=319, Evalue=3e-87,
Organism=Drosophila melanogaster, GI62472936, Length=477, Percent_Identity=36.0587002096436, Blast_Score=319, Evalue=3e-87,
Organism=Drosophila melanogaster, GI21356737, Length=477, Percent_Identity=36.0587002096436, Blast_Score=319, Evalue=3e-87,
Organism=Drosophila melanogaster, GI24666674, Length=481, Percent_Identity=27.2349272349272, Blast_Score=194, Evalue=9e-50,
Organism=Drosophila melanogaster, GI24638876, Length=439, Percent_Identity=30.751708428246, Blast_Score=182, Evalue=7e-46,
Organism=Drosophila melanogaster, GI24638878, Length=439, Percent_Identity=30.751708428246, Blast_Score=181, Evalue=8e-46,
Organism=Drosophila melanogaster, GI24668425, Length=491, Percent_Identity=24.847250509165, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24668417, Length=491, Percent_Identity=24.847250509165, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24668413, Length=491, Percent_Identity=24.847250509165, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI281360299, Length=353, Percent_Identity=27.1954674220963, Blast_Score=115, Evalue=8e-26,
Organism=Drosophila melanogaster, GI281360297, Length=353, Percent_Identity=27.1954674220963, Blast_Score=115, Evalue=8e-26,
Organism=Drosophila melanogaster, GI281360295, Length=353, Percent_Identity=27.1954674220963, Blast_Score=115, Evalue=8e-26,
Organism=Drosophila melanogaster, GI24586250, Length=353, Percent_Identity=27.1954674220963, Blast_Score=115, Evalue=8e-26,
Organism=Drosophila melanogaster, GI281360301, Length=353, Percent_Identity=27.1954674220963, Blast_Score=115, Evalue=8e-26,
Organism=Drosophila melanogaster, GI45552499, Length=356, Percent_Identity=26.685393258427, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI281360303, Length=356, Percent_Identity=26.685393258427, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI28571806, Length=482, Percent_Identity=21.5767634854772, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI28571798, Length=482, Percent_Identity=21.5767634854772, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI28571796, Length=482, Percent_Identity=21.5767634854772, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI28571794, Length=482, Percent_Identity=21.5767634854772, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI28571802, Length=482, Percent_Identity=21.5767634854772, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI28571800, Length=482, Percent_Identity=21.5767634854772, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI28574525, Length=466, Percent_Identity=21.0300429184549, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR011985 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: 1.2.1.60

Molecular weight: Translated: 53352; Mature: 53352

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU ; PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKHWINGKEVASEETFDNFNPATGEVICQVASGGEKEINAAVQAAKDAFPKWSKTPAKE
CCCCCCCCHHHCCHHCCCCCCCCCHHEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCHHH
RARLMRKLGELIDQNVAKLAELETLDTGLPIHQTKNVLIPRASHNFDFFAEVCTRMNGHS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCCC
YPVDDKMLNYTLYQPVGVCGLVSPWNVPFMTATWKTAPCLALGNTAVLKMSELSPLTANE
CCCCCHHHCEEEECCCCCEECCCCCCCCEEEEECCCCCEEEECCCEEEEECCCCCCCHHH
LGRLALEAGIPEGVFNVVQGLGSTAGHALVTHDDVRAISFTGGTATGKHILKHAGLKKYS
HHHHHHHCCCCHHHHHHHHHCCCCCCCEEEEECCCEEEEECCCCCHHHHHHHHCCCHHHH
MELGGKSPVLIFDDADLDRALDAALFTIFSLNGERCTAGSRIFIQETVYDEFVKQFAARA
HHCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCEECCCCEEEEHHHHHHHHHHHHHHHH
KRLIVGDPQDFNTQVGSMITRQHYDKVTGYIRIGLEEGATLLAGGLERPQNLPAHLQKGH
CEEEECCCCCHHHHHHHHHHHHHHHHHEEEEEEECCCCCEEECCCCCCCCCCCHHHCCCC
FIQPTVFADVDNRMRIAQEEIFGPVVCLMKFKDEAEALRLANDVEYGLASYIWTKDIAKA
CCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRLSNGIEAGMVFVNSQNVRDLRQPFGGIKASGIGREGGEYSFEVFAELKNVCISMHDHP
HHHCCCCCCCEEEEECCCHHHHHHHCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHCCCC
IPRWGL
CCCCCC
>Mature Secondary Structure
MIKHWINGKEVASEETFDNFNPATGEVICQVASGGEKEINAAVQAAKDAFPKWSKTPAKE
CCCCCCCCHHHCCHHCCCCCCCCCHHEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCHHH
RARLMRKLGELIDQNVAKLAELETLDTGLPIHQTKNVLIPRASHNFDFFAEVCTRMNGHS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCCC
YPVDDKMLNYTLYQPVGVCGLVSPWNVPFMTATWKTAPCLALGNTAVLKMSELSPLTANE
CCCCCHHHCEEEECCCCCEECCCCCCCCEEEEECCCCCEEEECCCEEEEECCCCCCCHHH
LGRLALEAGIPEGVFNVVQGLGSTAGHALVTHDDVRAISFTGGTATGKHILKHAGLKKYS
HHHHHHHCCCCHHHHHHHHHCCCCCCCEEEEECCCEEEEECCCCCHHHHHHHHCCCHHHH
MELGGKSPVLIFDDADLDRALDAALFTIFSLNGERCTAGSRIFIQETVYDEFVKQFAARA
HHCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCEECCCCEEEEHHHHHHHHHHHHHHHH
KRLIVGDPQDFNTQVGSMITRQHYDKVTGYIRIGLEEGATLLAGGLERPQNLPAHLQKGH
CEEEECCCCCHHHHHHHHHHHHHHHHHEEEEEEECCCCCEEECCCCCCCCCCCHHHCCCC
FIQPTVFADVDNRMRIAQEEIFGPVVCLMKFKDEAEALRLANDVEYGLASYIWTKDIAKA
CCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRLSNGIEAGMVFVNSQNVRDLRQPFGGIKASGIGREGGEYSFEVFAELKNVCISMHDHP
HHHCCCCCCCEEEEECCCHHHHHHHCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHCCCC
IPRWGL
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 5-carboxymethyl-2-hydroxymuconate semialdehyde; H2O; NAD+

Specific reaction: 5-carboxymethyl-2-hydroxymuconate semialdehyde + H2O + NAD+ = 5-carboxymethyl-2-hydroxymuconate + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7737515 [H]