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The map label for this gene is gpmA [H]

Identifier: 15603371

GI number: 15603371

Start: 1704487

End: 1705170

Strand: Reverse

Name: gpmA [H]

Synonym: PM1506

Alternate gene names: 15603371

Gene position: 1705170-1704487 (Counterclockwise)

Preceding gene: 15603375

Following gene: 15603366

Centisome position: 75.53

GC content: 41.52

Gene sequence:

>684_bases
ATGGAATTGGTCTTTATTCGCCACGGTTTCAGTGAGTGGAATGCCAAAAACCTATTCACAGGTTGGCGTGATGTCAACTT
AACAGAACGCGGTATCGAAGAAGCAAAATCAGCAGGCAAAAAATTACTCGAAGCCGGTTTTGAATTTGATATTGCTTTCA
CGTCTGTTTTAACGCGTGCAATTAAAACCTGTAACATTGTGTTAGAAGAATCTAACCAACTTTGGATCCCACAAGTGAAA
AACTGGCGTTTAAATGAGCGTCATTACGGTGCATTACAAGGCTTAGATAAAAAAGCCACTGCAGAACAATATGGTGATGA
GCAAGTCCATATTTGGCGTCGTTCTTACGATATTTCTCCTCCAGATTTAGATCCACAAGATCCTCATTCTGCCCATAACG
ACCGTCGTTATGCTCACTTACCAAGCGATGTGGTACCTGATGCAGAAAACTTAAAAATCACCCTTGAGCGTGTTTTACCT
TTCTGGGAAGACCAAATTGCCCCAGCTTTACTGGCGGGTAAACGTGTCCTTGTGACAGCACACGGCAACTCATTACGTGC
ATTGGCAAAACACATTGAAGGCATTTCTGATGCAGACATCATGGATTTAGAAATCCCAACCGGTCAGCCATTAGTGTACA
AATTAGATGACAATTTAAAAGTCGTGGAAAAATACTACCTTTAA

Upstream 100 bases:

>100_bases
TTTGCGACAGATCAGAAAAGCAAAGTATTTCCCTTTTAAAGCCGGCTGTTTTTTGCTATAACTTGCCATAGTTTTTTTAT
TAACATTGAGGAGATTTTTT

Downstream 100 bases:

>100_bases
TTGAAATCAAGAAAAATCGGGGCAATTGTCCCGATTTTTTTATGAAACTCAACCTAAAAAAAGTGCGGTCCTTTTTACCG
CACTTTTTTATCCACAATCG

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM [H]

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MELVFIRHGFSEWNAKNLFTGWRDVNLTERGIEEAKSAGKKLLEAGFEFDIAFTSVLTRAIKTCNIVLEESNQLWIPQVK
NWRLNERHYGALQGLDKKATAEQYGDEQVHIWRRSYDISPPDLDPQDPHSAHNDRRYAHLPSDVVPDAENLKITLERVLP
FWEDQIAPALLAGKRVLVTAHGNSLRALAKHIEGISDADIMDLEIPTGQPLVYKLDDNLKVVEKYYL

Sequences:

>Translated_227_residues
MELVFIRHGFSEWNAKNLFTGWRDVNLTERGIEEAKSAGKKLLEAGFEFDIAFTSVLTRAIKTCNIVLEESNQLWIPQVK
NWRLNERHYGALQGLDKKATAEQYGDEQVHIWRRSYDISPPDLDPQDPHSAHNDRRYAHLPSDVVPDAENLKITLERVLP
FWEDQIAPALLAGKRVLVTAHGNSLRALAKHIEGISDADIMDLEIPTGQPLVYKLDDNLKVVEKYYL
>Mature_227_residues
MELVFIRHGFSEWNAKNLFTGWRDVNLTERGIEEAKSAGKKLLEAGFEFDIAFTSVLTRAIKTCNIVLEESNQLWIPQVK
NWRLNERHYGALQGLDKKATAEQYGDEQVHIWRRSYDISPPDLDPQDPHSAHNDRRYAHLPSDVVPDAENLKITLERVLP
FWEDQIAPALLAGKRVLVTAHGNSLRALAKHIEGISDADIMDLEIPTGQPLVYKLDDNLKVVEKYYL

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily [H]

Homologues:

Organism=Homo sapiens, GI50593010, Length=220, Percent_Identity=53.6363636363636, Blast_Score=255, Evalue=3e-68,
Organism=Homo sapiens, GI4505753, Length=224, Percent_Identity=54.0178571428571, Blast_Score=244, Evalue=5e-65,
Organism=Homo sapiens, GI4502445, Length=225, Percent_Identity=49.7777777777778, Blast_Score=241, Evalue=3e-64,
Organism=Homo sapiens, GI40353764, Length=225, Percent_Identity=49.7777777777778, Blast_Score=241, Evalue=3e-64,
Organism=Homo sapiens, GI71274132, Length=224, Percent_Identity=52.2321428571429, Blast_Score=233, Evalue=8e-62,
Organism=Homo sapiens, GI310129614, Length=161, Percent_Identity=53.416149068323, Blast_Score=166, Evalue=2e-41,
Organism=Escherichia coli, GI1786970, Length=226, Percent_Identity=53.0973451327434, Blast_Score=262, Evalue=1e-71,
Organism=Saccharomyces cerevisiae, GI6322697, Length=227, Percent_Identity=53.3039647577093, Blast_Score=257, Evalue=1e-69,
Organism=Saccharomyces cerevisiae, GI6324516, Length=276, Percent_Identity=31.5217391304348, Blast_Score=131, Evalue=9e-32,
Organism=Saccharomyces cerevisiae, GI6320183, Length=284, Percent_Identity=32.7464788732394, Blast_Score=130, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6324857, Length=189, Percent_Identity=25.9259259259259, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24646216, Length=221, Percent_Identity=52.0361990950226, Blast_Score=236, Evalue=1e-62,
Organism=Drosophila melanogaster, GI85725270, Length=224, Percent_Identity=52.6785714285714, Blast_Score=228, Evalue=4e-60,
Organism=Drosophila melanogaster, GI85725272, Length=224, Percent_Identity=52.6785714285714, Blast_Score=228, Evalue=4e-60,
Organism=Drosophila melanogaster, GI24650981, Length=224, Percent_Identity=52.6785714285714, Blast_Score=228, Evalue=4e-60,
Organism=Drosophila melanogaster, GI28571815, Length=217, Percent_Identity=39.63133640553, Blast_Score=174, Evalue=6e-44,
Organism=Drosophila melanogaster, GI24648979, Length=217, Percent_Identity=39.63133640553, Blast_Score=174, Evalue=6e-44,
Organism=Drosophila melanogaster, GI28571817, Length=217, Percent_Identity=39.63133640553, Blast_Score=174, Evalue=6e-44,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR005952 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 25955; Mature: 25955

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELVFIRHGFSEWNAKNLFTGWRDVNLTERGIEEAKSAGKKLLEAGFEFDIAFTSVLTRA
CEEEEEECCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHH
IKTCNIVLEESNQLWIPQVKNWRLNERHYGALQGLDKKATAEQYGDEQVHIWRRSYDISP
HHHHEEEEECCCCEECCCCCCCCCCCCHHHHHHCCCCHHHHHHCCCCEEEEEEEECCCCC
PDLDPQDPHSAHNDRRYAHLPSDVVPDAENLKITLERVLPFWEDQIAPALLAGKRVLVTA
CCCCCCCCCCCCCCCEEEECCCCCCCCCCCCEEEHHHHCCHHHHHHHHHHHCCCEEEEEE
HGNSLRALAKHIEGISDADIMDLEIPTGQPLVYKLDDNLKVVEKYYL
CCCHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEECCCCEEHHHHCC
>Mature Secondary Structure
MELVFIRHGFSEWNAKNLFTGWRDVNLTERGIEEAKSAGKKLLEAGFEFDIAFTSVLTRA
CEEEEEECCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHH
IKTCNIVLEESNQLWIPQVKNWRLNERHYGALQGLDKKATAEQYGDEQVHIWRRSYDISP
HHHHEEEEECCCCEECCCCCCCCCCCCHHHHHHCCCCHHHHHHCCCCEEEEEEEECCCCC
PDLDPQDPHSAHNDRRYAHLPSDVVPDAENLKITLERVLPFWEDQIAPALLAGKRVLVTA
CCCCCCCCCCCCCCCEEEECCCCCCCCCCCCEEEHHHHCCHHHHHHHHHHHCCCEEEEEE
HGNSLRALAKHIEGISDADIMDLEIPTGQPLVYKLDDNLKVVEKYYL
CCCHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEECCCCEEHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA