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The map label for this gene is gpt [H]

Identifier: 15603234

GI number: 15603234

Start: 1560622

End: 1561083

Strand: Direct

Name: gpt [H]

Synonym: PM1369

Alternate gene names: 15603234

Gene position: 1560622-1561083 (Clockwise)

Preceding gene: 15603232

Following gene: 15603241

Centisome position: 69.13

GC content: 44.81

Gene sequence:

>462_bases
ATGAGCGAAAAATATGTAGTGACCTGGGACATGTTCCAAATGCACGCGCGTAAATTATCGGAGCGCTTACTTCCTGCTTC
ACAATGGAAAGGCATTATTGCTGTCAGCCGTGGTGGATTATTTCCTGCGGCAGTGCTTGCACGTGAACTGGGCATTCGTC
ATATCGAAACCGTCTGTATCGCCAGCTATCACGATCATGTTGAACAAGGCGAATTAAAAGTATTACATCGTGCCGAAGGT
GATGGTGAAGGTTTCATCGTAGTGGATGACTTAGTGGATACAGGCAATACAGCACGTGCTATCCGTGACATGTATCCAAA
AGCTAAATTTGTGACGGTATTCGCAAAACCCGCCGGTGCGGCATTAGTTGACGATTATGTGATCGATATTCCACAAAATA
CTTGGATTGAACAGCCTTGGGATTTAGGTTTAACCTTTGTGCCACCATTAGCCAGAAAATAA

Upstream 100 bases:

>100_bases
ATCAGTAAAATTATAGCATAAAAGGCGATTTCGCGTTATCCTAACGCAATTTTTTAATTTATGGGTAAATTTTACCCCCT
CTTTGTCAAAAGGTGTATTT

Downstream 100 bases:

>100_bases
TTACGTCGTTATTTTCGCTTTTCAAACATAAAAAATGCGAGTAATTAACTCGCATTTTTTGTTGTCTATTCATCGACTTA
GCTGGCGAATTTCGCCTTTA

Product: xanthine-guanine phosphoribosyltransferase

Products: NA

Alternate protein names: Xanthine-guanine phosphoribosyltransferase 1; XGPRT 1 [H]

Number of amino acids: Translated: 153; Mature: 152

Protein sequence:

>153_residues
MSEKYVVTWDMFQMHARKLSERLLPASQWKGIIAVSRGGLFPAAVLARELGIRHIETVCIASYHDHVEQGELKVLHRAEG
DGEGFIVVDDLVDTGNTARAIRDMYPKAKFVTVFAKPAGAALVDDYVIDIPQNTWIEQPWDLGLTFVPPLARK

Sequences:

>Translated_153_residues
MSEKYVVTWDMFQMHARKLSERLLPASQWKGIIAVSRGGLFPAAVLARELGIRHIETVCIASYHDHVEQGELKVLHRAEG
DGEGFIVVDDLVDTGNTARAIRDMYPKAKFVTVFAKPAGAALVDDYVIDIPQNTWIEQPWDLGLTFVPPLARK
>Mature_152_residues
SEKYVVTWDMFQMHARKLSERLLPASQWKGIIAVSRGGLFPAAVLARELGIRHIETVCIASYHDHVEQGELKVLHRAEGD
GEGFIVVDDLVDTGNTARAIRDMYPKAKFVTVFAKPAGAALVDDYVIDIPQNTWIEQPWDLGLTFVPPLARK

Specific function: Acts on guanine, xanthine and to a lesser extent hypoxanthine [H]

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786433, Length=153, Percent_Identity=76.4705882352941, Blast_Score=251, Evalue=2e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.22 [H]

Molecular weight: Translated: 17115; Mature: 16984

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKYVVTWDMFQMHARKLSERLLPASQWKGIIAVSRGGLFPAAVLARELGIRHIETVCI
CCCCEEEEHHHHHHHHHHHHHHCCCHHHCCCEEEEECCCCCHHHHHHHHHCHHHHHHHHH
ASYHDHVEQGELKVLHRAEGDGEGFIVVDDLVDTGNTARAIRDMYPKAKFVTVFAKPAGA
HHHHHCCCCCCEEEEEECCCCCCEEEEEECCCCCCCHHHHHHHHCCCCEEEEEEECCCCC
ALVDDYVIDIPQNTWIEQPWDLGLTFVPPLARK
EEECCEEEECCCCCCCCCCCCCCCEECCCCCCC
>Mature Secondary Structure 
SEKYVVTWDMFQMHARKLSERLLPASQWKGIIAVSRGGLFPAAVLARELGIRHIETVCI
CCCEEEEHHHHHHHHHHHHHHCCCHHHCCCEEEEECCCCCHHHHHHHHHCHHHHHHHHH
ASYHDHVEQGELKVLHRAEGDGEGFIVVDDLVDTGNTARAIRDMYPKAKFVTVFAKPAGA
HHHHHCCCCCCEEEEEECCCCCCEEEEEECCCCCCCHHHHHHHHCCCCEEEEEEECCCCC
ALVDDYVIDIPQNTWIEQPWDLGLTFVPPLARK
EEECCEEEECCCCCCCCCCCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA