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The map label for this gene is deoC

Identifier: 15603208

GI number: 15603208

Start: 1536444

End: 1537115

Strand: Direct

Name: deoC

Synonym: PM1343

Alternate gene names: 15603208

Gene position: 1536444-1537115 (Clockwise)

Preceding gene: 15603202

Following gene: 15603209

Centisome position: 68.06

GC content: 41.67

Gene sequence:

>672_bases
ATGGATGCAAAGCAAATTGCACAGTTTATCGATCATACTGCGTTAACCGCGGAGAAAACGGAACAAGATATTATTCAATT
ATGTGATGAAGCCATTACACATCAGTTTTGGTCAGTTTGTATTAATTCTGCCTATATTCCGTTAGCCAAACAAAAATTAG
CTGGGACGCCAGTCAAAATCTGTACTGTAGTGGGTTTTCCATTAGGTGCAAATTTAAGCACGGTTAAGGCCTTTGAAACG
ACAGAAGCGATCAAAGCCGGGGCAGATGAAATTGATATGGTGATTAATGTCGGTTGGATTAAATCAAATAAATGGGATGC
GGTAGAAAAAGATATTGCGACCGTGTTAGCTGCTTGTGCAGGAAAACCATTAAAAGTCATTTTAGAAACGTGCTTATTAA
GTAAAGACGAAATTGTAAAAGCATGTGAAATTTGTAAAACGCTCAATGTGGCGTTTGTCAAAACATCAACTGGTTTCAAT
CGTGGTGGGGCAACAAAGGAAGATGTTGCTTTGATGAAACGAACCGTAGGCGATATTGGAGTCAAAGCGTCTGGCGGCGT
GCGTGATACGGAGACCGCAATCGCGATGATTAATGCGGGGGCTAGCCGTATCGGTGCAAGTGCAGGGATTGCGATTATCC
ATGGTTTACAGGACGTAAGCAGTACCTATTAA

Upstream 100 bases:

>100_bases
ATTATTTTTTTGTTAACTTTGTCACATTTTATGTATTATTTTCGTGTATAATATGAGCATATCGTTCAGCTATAGTTAAA
TTGTCAATGAGGAAAGAAGT

Downstream 100 bases:

>100_bases
TAAATCACTGAGCTTGCTATGGAAAAAATGACGTCTCGCATTCAGAAATTGGAGTTTCTACTTAAGCAAATGGACAAAAT
TCATCTGCGAGATGCGGCAG

Product: deoxyribose-phosphate aldolase

Products: NA

Alternate protein names: Phosphodeoxyriboaldolase; DERA; Deoxyriboaldolase

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MDAKQIAQFIDHTALTAEKTEQDIIQLCDEAITHQFWSVCINSAYIPLAKQKLAGTPVKICTVVGFPLGANLSTVKAFET
TEAIKAGADEIDMVINVGWIKSNKWDAVEKDIATVLAACAGKPLKVILETCLLSKDEIVKACEICKTLNVAFVKTSTGFN
RGGATKEDVALMKRTVGDIGVKASGGVRDTETAIAMINAGASRIGASAGIAIIHGLQDVSSTY

Sequences:

>Translated_223_residues
MDAKQIAQFIDHTALTAEKTEQDIIQLCDEAITHQFWSVCINSAYIPLAKQKLAGTPVKICTVVGFPLGANLSTVKAFET
TEAIKAGADEIDMVINVGWIKSNKWDAVEKDIATVLAACAGKPLKVILETCLLSKDEIVKACEICKTLNVAFVKTSTGFN
RGGATKEDVALMKRTVGDIGVKASGGVRDTETAIAMINAGASRIGASAGIAIIHGLQDVSSTY
>Mature_223_residues
MDAKQIAQFIDHTALTAEKTEQDIIQLCDEAITHQFWSVCINSAYIPLAKQKLAGTPVKICTVVGFPLGANLSTVKAFET
TEAIKAGADEIDMVINVGWIKSNKWDAVEKDIATVLAACAGKPLKVILETCLLSKDEIVKACEICKTLNVAFVKTSTGFN
RGGATKEDVALMKRTVGDIGVKASGGVRDTETAIAMINAGASRIGASAGIAIIHGLQDVSSTY

Specific function: Nucleotide and deoxyribonucleotide catabolism. [C]

COG id: COG0274

COG function: function code F; Deoxyribose-phosphate aldolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the deoC/fbaB aldolase family. DeoC type 1 subfamily

Homologues:

Organism=Homo sapiens, GI116063554, Length=227, Percent_Identity=29.0748898678414, Blast_Score=72, Evalue=4e-13,
Organism=Escherichia coli, GI1790841, Length=202, Percent_Identity=35.1485148514851, Blast_Score=82, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DEOC_PASMU (P57937)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_246282.1
- ProteinModelPortal:   P57937
- SMR:   P57937
- GeneID:   1244690
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM1343
- NMPDR:   fig|272843.1.peg.1344
- HOGENOM:   HBG636421
- OMA:   GANTPEV
- ProtClustDB:   PRK00507
- BioCyc:   PMUL272843:PM1343-MONOMER
- BRENDA:   4.1.2.4
- GO:   GO:0005737
- HAMAP:   MF_00114
- InterPro:   IPR013785
- InterPro:   IPR011343
- InterPro:   IPR002915
- InterPro:   IPR022979
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR10889
- PIRSF:   PIRSF001357
- TIGRFAMs:   TIGR00126

Pfam domain/function: PF01791 DeoC

EC number: =4.1.2.4

Molecular weight: Translated: 23586; Mature: 23586

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: ACT_SITE 154-154 ACT_SITE 182-182

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAKQIAQFIDHTALTAEKTEQDIIQLCDEAITHQFWSVCINSAYIPLAKQKLAGTPVKI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCEE
CTVVGFPLGANLSTVKAFETTEAIKAGADEIDMVINVGWIKSNKWDAVEKDIATVLAACA
HEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHC
GKPLKVILETCLLSKDEIVKACEICKTLNVAFVKTSTGFNRGGATKEDVALMKRTVGDIG
CCHHHHHHHHHHCCHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCC
VKASGGVRDTETAIAMINAGASRIGASAGIAIIHGLQDVSSTY
CCCCCCCCHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MDAKQIAQFIDHTALTAEKTEQDIIQLCDEAITHQFWSVCINSAYIPLAKQKLAGTPVKI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCEE
CTVVGFPLGANLSTVKAFETTEAIKAGADEIDMVINVGWIKSNKWDAVEKDIATVLAACA
HEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHC
GKPLKVILETCLLSKDEIVKACEICKTLNVAFVKTSTGFNRGGATKEDVALMKRTVGDIG
CCHHHHHHHHHHCCHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCC
VKASGGVRDTETAIAMINAGASRIGASAGIAIIHGLQDVSSTY
CCCCCCCCHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100