Click here to switch to the map view.

The map label for this gene is nqrA

Identifier: 15603193

GI number: 15603193

Start: 1520407

End: 1521747

Strand: Direct

Name: nqrA

Synonym: PM1328

Alternate gene names: 15603193

Gene position: 1520407-1521747 (Clockwise)

Preceding gene: 15603192

Following gene: 15603194

Centisome position: 67.35

GC content: 42.58

Gene sequence:

>1341_bases
ATGATTACGATTAAAAAAGGCTTGAATCTTCCTATTTCGGGAAGCCCAGAGCAGGTAATCCGTGATGGCAATGCTATCAC
TGAAGTTGCTTTGCTTGGTGAAGAGTATGTGGGAATGCGCCCTTCAATGAAGGTGCGTGAAGGTGATGTTGTGAAAAAAG
GCCAAGTGCTTTTTGAAGATAAAAAGAACCCTGGTGTGGTTTTCACAGCCCCTGCAAGTGGTACTGTAACTGCGATTCAT
CGTGGTGCTAAGCGAGTTTTACAATCTGTAGTAATTAAAATTGAAGGTAATGAACAAATTACTTTTGAAAAATATACAAC
AGAACAATTAAACCAACTTACTTCAGAGCAAGTTCGTCAAAATTTACAAGCTTCTGGATTATGGACCGCACTTCGTACGC
GTCCGTTCAGTAAAGTGCCTGCCGTCGATGCCACACCCGTATCGATTTTCGTGAATGCGATGGATACCAATCCATTATGT
GCCGATCCACAAGTGATCGTGCAACAATCTGCGCAAGCTTTTGAAGCGGGTCTGACTGTATTAAGTCGTTTACATGAGGG
GAAAGTGTACCTGTGTAAAGCGGCGAATGCGAGCATTCCAAGCCCAAGCATTGCCAATCTTGACGTGAAAGAATTTGCAG
GTCCACATCCAGCTGGGTTAAGTGGTACGCATATTCACTTTATTGATCCTGTGAGTGCAACCAAATTTGTTTGGTATATC
AATTACCAAGATGTGATAGCGGTGGGTAAATTATTTACCACAGGTGAATTAGATGTTTCACGCGTAGTGTCCTTAGCTGG
TCCACAAGTGAAAAATCCAAGATTAGTACGTACCGTATTAGGTGCAAACCTTTCCCAATTAACAGCGAATGAAGTGAAAG
ACGGTGAAAATCGCGTGATTTCAGGTTCAGTATTAAGTGGTGCAAAAGCTGCAGGTCCTGTTGATTATTTAGGTCGTTAC
GCATTGCAAGTTTCAGTACTTGAAGAAGGTCGTGAGAAAGAATTTCTAGGTTGGATCATGCCGGGTGCGAATAAATACTC
ACTTTCACGCACGGTGTTAGGGCATTTCTCTAAAAAATTATTTAATTTTACCACCGCACTTAATGGCGGTGAGCGTGCGA
TGGTACCTATCGGTGCTTATGAGCGTGTGATGCCATTGGATATTATTCCAACATTATTACTGCGTGATTTGGCAGCAGGC
GATACCGATTCTGCACAGGCGTTAGGGTGTTTAGAGCTAGATGAAGAAGATTTAGCCCTTTGTACCTTTGTTTGCCCTGG
TAAAAATGAATATGGTCCGCTCTTACGTCAAGCTTTAGATAAGATCGAGAAGGAAGGTTAA

Upstream 100 bases:

>100_bases
AGCGTTTGCATGATCTTGCTGAAATCATTACTCAAGACGAGGTTATAGTGCTAGTCACTGTAACTATATTTTTAATCTGA
CTAAAAGTAGTGCAAACAAT

Downstream 100 bases:

>100_bases
AAATGGGTTTAAAACATTTTATTGAAAAAATTGAACCTGCGTTTTTACCGGGTGGTAAATATGAGAAATGGTATGCATTA
TTTGAAGCAACCGCCACCTT

Product: Na(+)-translocating NADH-quinone reductase subunit A

Products: NA

Alternate protein names: Na(+)-NQR subunit A; Na(+)-translocating NQR subunit A; NQR complex subunit A; NQR-1 subunit A

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MITIKKGLNLPISGSPEQVIRDGNAITEVALLGEEYVGMRPSMKVREGDVVKKGQVLFEDKKNPGVVFTAPASGTVTAIH
RGAKRVLQSVVIKIEGNEQITFEKYTTEQLNQLTSEQVRQNLQASGLWTALRTRPFSKVPAVDATPVSIFVNAMDTNPLC
ADPQVIVQQSAQAFEAGLTVLSRLHEGKVYLCKAANASIPSPSIANLDVKEFAGPHPAGLSGTHIHFIDPVSATKFVWYI
NYQDVIAVGKLFTTGELDVSRVVSLAGPQVKNPRLVRTVLGANLSQLTANEVKDGENRVISGSVLSGAKAAGPVDYLGRY
ALQVSVLEEGREKEFLGWIMPGANKYSLSRTVLGHFSKKLFNFTTALNGGERAMVPIGAYERVMPLDIIPTLLLRDLAAG
DTDSAQALGCLELDEEDLALCTFVCPGKNEYGPLLRQALDKIEKEG

Sequences:

>Translated_446_residues
MITIKKGLNLPISGSPEQVIRDGNAITEVALLGEEYVGMRPSMKVREGDVVKKGQVLFEDKKNPGVVFTAPASGTVTAIH
RGAKRVLQSVVIKIEGNEQITFEKYTTEQLNQLTSEQVRQNLQASGLWTALRTRPFSKVPAVDATPVSIFVNAMDTNPLC
ADPQVIVQQSAQAFEAGLTVLSRLHEGKVYLCKAANASIPSPSIANLDVKEFAGPHPAGLSGTHIHFIDPVSATKFVWYI
NYQDVIAVGKLFTTGELDVSRVVSLAGPQVKNPRLVRTVLGANLSQLTANEVKDGENRVISGSVLSGAKAAGPVDYLGRY
ALQVSVLEEGREKEFLGWIMPGANKYSLSRTVLGHFSKKLFNFTTALNGGERAMVPIGAYERVMPLDIIPTLLLRDLAAG
DTDSAQALGCLELDEEDLALCTFVCPGKNEYGPLLRQALDKIEKEG
>Mature_446_residues
MITIKKGLNLPISGSPEQVIRDGNAITEVALLGEEYVGMRPSMKVREGDVVKKGQVLFEDKKNPGVVFTAPASGTVTAIH
RGAKRVLQSVVIKIEGNEQITFEKYTTEQLNQLTSEQVRQNLQASGLWTALRTRPFSKVPAVDATPVSIFVNAMDTNPLC
ADPQVIVQQSAQAFEAGLTVLSRLHEGKVYLCKAANASIPSPSIANLDVKEFAGPHPAGLSGTHIHFIDPVSATKFVWYI
NYQDVIAVGKLFTTGELDVSRVVSLAGPQVKNPRLVRTVLGANLSQLTANEVKDGENRVISGSVLSGAKAAGPVDYLGRY
ALQVSVLEEGREKEFLGWIMPGANKYSLSRTVLGHFSKKLFNFTTALNGGERAMVPIGAYERVMPLDIIPTLLLRDLAAG
DTDSAQALGCLELDEEDLALCTFVCPGKNEYGPLLRQALDKIEKEG

Specific function: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to nqrE are probably involved in the second step, the conversion of ubisemiqui

COG id: COG1726

COG function: function code C; Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nqrA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NQRA_PASMU (Q9CLB1)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_246266.1
- PRIDE:   Q9CLB1
- GeneID:   1244675
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM1328
- NMPDR:   fig|272843.1.peg.1329
- HOGENOM:   HBG413878
- OMA:   EYGPILR
- ProtClustDB:   PRK05352
- BioCyc:   PMUL272843:PM1328-MONOMER
- HAMAP:   MF_00425
- InterPro:   IPR008703
- InterPro:   IPR022615
- TIGRFAMs:   TIGR01936

Pfam domain/function: PF05896 NQRA; PF11973 NQRA_SLBB

EC number: NA

Molecular weight: Translated: 48169; Mature: 48169

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITIKKGLNLPISGSPEQVIRDGNAITEVALLGEEYVGMRPSMKVREGDVVKKGQVLFED
CEEECCCCCCCCCCCHHHHHHCCCHHHHHHHHCHHHCCCCCCCEECCCCCEECCCEEEEC
KKNPGVVFTAPASGTVTAIHRGAKRVLQSVVIKIEGNEQITFEKYTTEQLNQLTSEQVRQ
CCCCCEEEECCCCCCHHHHHHHHHHHHHHEEEEECCCCEEEEEEHHHHHHHHHHHHHHHH
NLQASGLWTALRTRPFSKVPAVDATPVSIFVNAMDTNPLCADPQVIVQQSAQAFEAGLTV
HHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHH
LSRLHEGKVYLCKAANASIPSPSIANLDVKEFAGPHPAGLSGTHIHFIDPVSATKFVWYI
HHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHCCCCCCCCCCCEEEEECCCCCCEEEEEE
NYQDVIAVGKLFTTGELDVSRVVSLAGPQVKNPRLVRTVLGANLSQLTANEVKDGENRVI
CCHHHHHHHCEEECCCCCHHHHHHHCCCCCCCCHHHHHHHCCCHHHHHHHHCCCCCCEEE
SGSVLSGAKAAGPVDYLGRYALQVSVLEEGREKEFLGWIMPGANKYSLSRTVLGHFSKKL
ECHHHCCCCCCCCHHHHHHHHEEEEEHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHH
FNFTTALNGGERAMVPIGAYERVMPLDIIPTLLLRDLAAGDTDSAQALGCLELDEEDLAL
HHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCHHEEEEEECCCCCEEE
CTFVCPGKNEYGPLLRQALDKIEKEG
EEEECCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MITIKKGLNLPISGSPEQVIRDGNAITEVALLGEEYVGMRPSMKVREGDVVKKGQVLFED
CEEECCCCCCCCCCCHHHHHHCCCHHHHHHHHCHHHCCCCCCCEECCCCCEECCCEEEEC
KKNPGVVFTAPASGTVTAIHRGAKRVLQSVVIKIEGNEQITFEKYTTEQLNQLTSEQVRQ
CCCCCEEEECCCCCCHHHHHHHHHHHHHHEEEEECCCCEEEEEEHHHHHHHHHHHHHHHH
NLQASGLWTALRTRPFSKVPAVDATPVSIFVNAMDTNPLCADPQVIVQQSAQAFEAGLTV
HHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHH
LSRLHEGKVYLCKAANASIPSPSIANLDVKEFAGPHPAGLSGTHIHFIDPVSATKFVWYI
HHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHCCCCCCCCCCCEEEEECCCCCCEEEEEE
NYQDVIAVGKLFTTGELDVSRVVSLAGPQVKNPRLVRTVLGANLSQLTANEVKDGENRVI
CCHHHHHHHCEEECCCCCHHHHHHHCCCCCCCCHHHHHHHCCCHHHHHHHHCCCCCCEEE
SGSVLSGAKAAGPVDYLGRYALQVSVLEEGREKEFLGWIMPGANKYSLSRTVLGHFSKKL
ECHHHCCCCCCCCHHHHHHHHEEEEEHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHH
FNFTTALNGGERAMVPIGAYERVMPLDIIPTLLLRDLAAGDTDSAQALGCLELDEEDLAL
HHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCHHEEEEEECCCCCEEE
CTFVCPGKNEYGPLLRQALDKIEKEG
EEEECCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11248100