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The map label for this gene is coaD

Identifier: 15603169

GI number: 15603169

Start: 1499003

End: 1499479

Strand: Reverse

Name: coaD

Synonym: PM1304

Alternate gene names: 15603169

Gene position: 1499479-1499003 (Counterclockwise)

Preceding gene: 15603170

Following gene: 15603167

Centisome position: 66.42

GC content: 41.3

Gene sequence:

>477_bases
ATGATTACGGTTATTTACCCTGGTACCTTTGATCCCATTACGAATGGACATCTAGATATTATTCAACGTACCGCACGTTT
ATTTCCCAATGTGTTAGTCGCCGTGGCGTCTAATCCAAATAAAAAGCCCTTATTTGATCTGGCGACACGAGTGGAATTAG
TCAAGCAAGCCGTCGCTCACTTACCGAATGTGACTGTCGTGGGTTTTTTAGATTTATTAGCCGATGTGGTCAAGGAACGG
AATATCACAGCGATTATTCGTGGTGTACGCAGTGCAAGCGATTTTGACTATGAATTACAGCTTGCCCACTTAAATCGCTT
ATTAACCAATGGAGTAGAAAGTTTATTTTTCCCACCGTCTGAACGTTGGTCATATGTGTCCTCTACTATGATTCGTGAAA
TCCATTTACATCATGGCGATGTAAGTCAACTCGTGCCCGAAGTCGTTTTTCACGCCTTACAAAACTTAAAAAAATAG

Upstream 100 bases:

>100_bases
GTGAGCGTTATGGCAATGCGGGTTATGAAGTCCTGATTGAAAATCGTGGCGCCTTACAACGTTTGTTAGATTTATTAGAT
CCTTATTTAAGTAAAACAGT

Downstream 100 bases:

>100_bases
TTCACTACGATGAAAAAAGGGGAAATATGTTTTCCCCTTATGCTTGATATCCCGCTAACAAAGCTTGCCAGTCTTGTTCA
CTGAATTGAATTTTCATCCG

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 158; Mature: 158

Protein sequence:

>158_residues
MITVIYPGTFDPITNGHLDIIQRTARLFPNVLVAVASNPNKKPLFDLATRVELVKQAVAHLPNVTVVGFLDLLADVVKER
NITAIIRGVRSASDFDYELQLAHLNRLLTNGVESLFFPPSERWSYVSSTMIREIHLHHGDVSQLVPEVVFHALQNLKK

Sequences:

>Translated_158_residues
MITVIYPGTFDPITNGHLDIIQRTARLFPNVLVAVASNPNKKPLFDLATRVELVKQAVAHLPNVTVVGFLDLLADVVKER
NITAIIRGVRSASDFDYELQLAHLNRLLTNGVESLFFPPSERWSYVSSTMIREIHLHHGDVSQLVPEVVFHALQNLKK
>Mature_158_residues
MITVIYPGTFDPITNGHLDIIQRTARLFPNVLVAVASNPNKKPLFDLATRVELVKQAVAHLPNVTVVGFLDLLADVVKER
NITAIIRGVRSASDFDYELQLAHLNRLLTNGVESLFFPPSERWSYVSSTMIREIHLHHGDVSQLVPEVVFHALQNLKK

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=150, Percent_Identity=52, Blast_Score=181, Evalue=3e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_PASMU (Q9CLD4)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_246242.1
- ProteinModelPortal:   Q9CLD4
- SMR:   Q9CLD4
- GeneID:   1244651
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM1304
- NMPDR:   fig|272843.1.peg.1305
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- ProtClustDB:   PRK00168
- BioCyc:   PMUL272843:PM1304-MONOMER
- BRENDA:   2.7.7.3
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 17731; Mature: 17731

Theoretical pI: Translated: 7.98; Mature: 7.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITVIYPGTFDPITNGHLDIIQRTARLFPNVLVAVASNPNKKPLFDLATRVELVKQAVAH
CEEEEECCCCCCCCCCHHHHHHHHHHHHHHHEEHCCCCCCCCHHHHHHHHHHHHHHHHHH
LPNVTVVGFLDLLADVVKERNITAIIRGVRSASDFDYELQLAHLNRLLTNGVESLFFPPS
CCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
ERWSYVSSTMIREIHLHHGDVSQLVPEVVFHALQNLKK
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MITVIYPGTFDPITNGHLDIIQRTARLFPNVLVAVASNPNKKPLFDLATRVELVKQAVAH
CEEEEECCCCCCCCCCHHHHHHHHHHHHHHHEEHCCCCCCCCHHHHHHHHHHHHHHHHHH
LPNVTVVGFLDLLADVVKERNITAIIRGVRSASDFDYELQLAHLNRLLTNGVESLFFPPS
CCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
ERWSYVSSTMIREIHLHHGDVSQLVPEVVFHALQNLKK
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100