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The map label for this gene is lyx

Identifier: 15603112

GI number: 15603112

Start: 1439828

End: 1441279

Strand: Reverse

Name: lyx

Synonym: PM1247

Alternate gene names: 15603112

Gene position: 1441279-1439828 (Counterclockwise)

Preceding gene: 15603113

Following gene: 15603111

Centisome position: 63.84

GC content: 44.63

Gene sequence:

>1452_bases
GTGAATTATTACTTAGGCATAGACTGTGGTGGGACGTTTATCAAAGCAGCACTCTTTGATAAAACGGGAAAAATGTTTAG
TTGTGTCCGTGAAAATGTGCAAGTCATCAGCGAACAAGCGGGCTATGCTGAACGTGATATGGATGAGTTATGGCAAATTT
TTGCCCGTGTCATTCGTCAAACGATTGAGCGTAGTCAAGTTTCCCCCCAACATATTAAAGGGATAGGAATCTCTGCACAG
GGCAAAGGGGCTTTCCTATTAGATCAAGAAAATAAACCGCTTGGTCGAGGAATTTTATCTTCCGATCAGCGTGCGTTAAC
GCTTGTCAAACAATGGCAAGAACAAGGGATCCCTGAGCAATTATATCCACATACACGACAAACACTCTGGACAGGTCATC
CTGTTTCTATATTACGTTGGTTAAAAGAACATGAGCCGGAGCGTTATCAACGAATTGGTTCAATTCTGATGTCACATGAT
TACTTGCGTTTTTGTTTAACTGGTGAGCTACACTGTGAAGAAACCAATATATCTGAATCAAATCTCTACAATATTCATAG
CGGTCAATACGATCCCAAACTTGCCGAGCTGCTCGGGTTAGAAGGCATTATTGCGAAGCTCCCACCGGTTATCGCGGCTA
ACCAAATTGCGGGATATGTCACGCCAAAAGCAGCTGAACTCACCGGATTGGCTGTAGGAACCGCTGTCGTCGGTGGTCTT
TTTGATGTGGTATCAACCGCACTTTGTGCCGGTCTGGATGATGAAACCAAACTGAATGCTGTATTGGGCACTTGGTCGGT
GGTGAGTGGGGTGACTCAACATATCGATCAGCAACAAACACTGCCTTTTGTTTATGGATGTTATGCGGAAGCTGGCAAAT
TCATAGTCCATGAAGCCAGCCCGACTTCCGCAGGAAATTTAGAATGGTTCGTCAAACAGTGGCATTTGGATTATGCACAC
ATTAATCAGCATGTTGCATCCCTCGAACCTGCCTCAAGCTCTGTCTTATTTGTGCCATTCCTATACGGTTCCAATGCGGG
ACTAGGTATGCAAGCTTGTTTCTATGGTATGCAAGCTCACCATACCCAAGCACATCTACTCCAAGCCATTTACGAAGGGG
TACTGTTCAGTTTAATGCACCATTTAGAGCGCATGCGAAAACGCTTCCCACAAGCGAACCTGTTGCGTGTCACAGGCGGA
CCAACCAAGTCCCCTATTTGGTTACAAATGTTGGCTGATTTCACAGGAATGCGATTAGAAATTCCACAAATCGAAGAAAC
CGGCTGCTTAGGGGCGGCATTAATGGCAATGCAAGGGGTAAATGAATCAGCAGATGTCTTTCAAGCACAATCTATGCTGC
ATGTGGAACCGAATCCGGCTTATTTTGCAGCTTACCAAGCTAAATATCAACGCTATCAACAACTTACTACTGCCTTAAAA
GCAATGCTTTAA

Upstream 100 bases:

>100_bases
TAAAACCACCTCAAATTGTACATTTGGTGCCGACCAAAAAACCTTATTCATTACAGCGACAAATAGTCTTTATCGGTTAA
CTTGTTATTAAGGATGGACT

Downstream 100 bases:

>100_bases
TTGATAATGAGGAACAATATGGCAAAACCACTTATTCAACTTGCACTAGATTCGCTTGATTTAGAAAGCGCGGTTGTCAC
CGCCAAAAATGCGGCTGATT

Product: L-xylulose kinase

Products: NA

Alternate protein names: L-xylulokinase

Number of amino acids: Translated: 483; Mature: 483

Protein sequence:

>483_residues
MNYYLGIDCGGTFIKAALFDKTGKMFSCVRENVQVISEQAGYAERDMDELWQIFARVIRQTIERSQVSPQHIKGIGISAQ
GKGAFLLDQENKPLGRGILSSDQRALTLVKQWQEQGIPEQLYPHTRQTLWTGHPVSILRWLKEHEPERYQRIGSILMSHD
YLRFCLTGELHCEETNISESNLYNIHSGQYDPKLAELLGLEGIIAKLPPVIAANQIAGYVTPKAAELTGLAVGTAVVGGL
FDVVSTALCAGLDDETKLNAVLGTWSVVSGVTQHIDQQQTLPFVYGCYAEAGKFIVHEASPTSAGNLEWFVKQWHLDYAH
INQHVASLEPASSSVLFVPFLYGSNAGLGMQACFYGMQAHHTQAHLLQAIYEGVLFSLMHHLERMRKRFPQANLLRVTGG
PTKSPIWLQMLADFTGMRLEIPQIEETGCLGAALMAMQGVNESADVFQAQSMLHVEPNPAYFAAYQAKYQRYQQLTTALK
AML

Sequences:

>Translated_483_residues
MNYYLGIDCGGTFIKAALFDKTGKMFSCVRENVQVISEQAGYAERDMDELWQIFARVIRQTIERSQVSPQHIKGIGISAQ
GKGAFLLDQENKPLGRGILSSDQRALTLVKQWQEQGIPEQLYPHTRQTLWTGHPVSILRWLKEHEPERYQRIGSILMSHD
YLRFCLTGELHCEETNISESNLYNIHSGQYDPKLAELLGLEGIIAKLPPVIAANQIAGYVTPKAAELTGLAVGTAVVGGL
FDVVSTALCAGLDDETKLNAVLGTWSVVSGVTQHIDQQQTLPFVYGCYAEAGKFIVHEASPTSAGNLEWFVKQWHLDYAH
INQHVASLEPASSSVLFVPFLYGSNAGLGMQACFYGMQAHHTQAHLLQAIYEGVLFSLMHHLERMRKRFPQANLLRVTGG
PTKSPIWLQMLADFTGMRLEIPQIEETGCLGAALMAMQGVNESADVFQAQSMLHVEPNPAYFAAYQAKYQRYQQLTTALK
AML
>Mature_483_residues
MNYYLGIDCGGTFIKAALFDKTGKMFSCVRENVQVISEQAGYAERDMDELWQIFARVIRQTIERSQVSPQHIKGIGISAQ
GKGAFLLDQENKPLGRGILSSDQRALTLVKQWQEQGIPEQLYPHTRQTLWTGHPVSILRWLKEHEPERYQRIGSILMSHD
YLRFCLTGELHCEETNISESNLYNIHSGQYDPKLAELLGLEGIIAKLPPVIAANQIAGYVTPKAAELTGLAVGTAVVGGL
FDVVSTALCAGLDDETKLNAVLGTWSVVSGVTQHIDQQQTLPFVYGCYAEAGKFIVHEASPTSAGNLEWFVKQWHLDYAH
INQHVASLEPASSSVLFVPFLYGSNAGLGMQACFYGMQAHHTQAHLLQAIYEGVLFSLMHHLERMRKRFPQANLLRVTGG
PTKSPIWLQMLADFTGMRLEIPQIEETGCLGAALMAMQGVNESADVFQAQSMLHVEPNPAYFAAYQAKYQRYQQLTTALK
AML

Specific function: L-lyxose utilization. [C]

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family

Homologues:

Organism=Escherichia coli, GI1790005, Length=486, Percent_Identity=58.641975308642, Blast_Score=584, Evalue=1e-168,
Organism=Escherichia coli, GI1789987, Length=487, Percent_Identity=25.2566735112936, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1787789, Length=509, Percent_Identity=22.3968565815324, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1789168, Length=468, Percent_Identity=23.0769230769231, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790361, Length=474, Percent_Identity=21.3080168776371, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1790338, Length=461, Percent_Identity=24.0780911062907, Blast_Score=83, Evalue=4e-17,
Organism=Drosophila melanogaster, GI17864214, Length=469, Percent_Identity=24.7334754797441, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24654573, Length=402, Percent_Identity=25.8706467661692, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LYXK_PASMU (P57928)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_246184.1
- ProteinModelPortal:   P57928
- SMR:   P57928
- GeneID:   1244594
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM1247
- NMPDR:   fig|272843.1.peg.1247
- HOGENOM:   HBG299886
- OMA:   SEYHISA
- ProtClustDB:   CLSK870414
- BioCyc:   PMUL272843:PM1247-MONOMER
- BRENDA:   2.7.1.53
- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- PANTHER:   PTHR10196

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N

EC number: =2.7.1.53

Molecular weight: Translated: 53674; Mature: 53674

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00933 FGGY_KINASES_1; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYYLGIDCGGTFIKAALFDKTGKMFSCVRENVQVISEQAGYAERDMDELWQIFARVIRQ
CCEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
TIERSQVSPQHIKGIGISAQGKGAFLLDQENKPLGRGILSSDQRALTLVKQWQEQGIPEQ
HHHHHCCCHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHH
LYPHTRQTLWTGHPVSILRWLKEHEPERYQRIGSILMSHDYLRFCLTGELHCEETNISES
HCCCHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCC
NLYNIHSGQYDPKLAELLGLEGIIAKLPPVIAANQIAGYVTPKAAELTGLAVGTAVVGGL
CEEECCCCCCCHHHHHHHCHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
FDVVSTALCAGLDDETKLNAVLGTWSVVSGVTQHIDQQQTLPFVYGCYAEAGKFIVHEAS
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHHCCCCHHEEEHHHCCCEEEEECC
PTSAGNLEWFVKQWHLDYAHINQHVASLEPASSSVLFVPFLYGSNAGLGMQACFYGMQAH
CCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHC
HTQAHLLQAIYEGVLFSLMHHLERMRKRFPQANLLRVTGGPTKSPIWLQMLADFTGMRLE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHCCCEEE
IPQIEETGCLGAALMAMQGVNESADVFQAQSMLHVEPNPAYFAAYQAKYQRYQQLTTALK
CCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCEEEECCCCCHHHHHHHHHHHHHHHHHHHH
AML
HHC
>Mature Secondary Structure
MNYYLGIDCGGTFIKAALFDKTGKMFSCVRENVQVISEQAGYAERDMDELWQIFARVIRQ
CCEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
TIERSQVSPQHIKGIGISAQGKGAFLLDQENKPLGRGILSSDQRALTLVKQWQEQGIPEQ
HHHHHCCCHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHH
LYPHTRQTLWTGHPVSILRWLKEHEPERYQRIGSILMSHDYLRFCLTGELHCEETNISES
HCCCHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCC
NLYNIHSGQYDPKLAELLGLEGIIAKLPPVIAANQIAGYVTPKAAELTGLAVGTAVVGGL
CEEECCCCCCCHHHHHHHCHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
FDVVSTALCAGLDDETKLNAVLGTWSVVSGVTQHIDQQQTLPFVYGCYAEAGKFIVHEAS
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHHCCCCHHEEEHHHCCCEEEEECC
PTSAGNLEWFVKQWHLDYAHINQHVASLEPASSSVLFVPFLYGSNAGLGMQACFYGMQAH
CCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHC
HTQAHLLQAIYEGVLFSLMHHLERMRKRFPQANLLRVTGGPTKSPIWLQMLADFTGMRLE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHCCCEEE
IPQIEETGCLGAALMAMQGVNESADVFQAQSMLHVEPNPAYFAAYQAKYQRYQQLTTALK
CCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCEEEECCCCCHHHHHHHHHHHHHHHHHHHH
AML
HHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11248100