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The map label for this gene is ulaD [H]

Identifier: 15603111

GI number: 15603111

Start: 1439165

End: 1439809

Strand: Reverse

Name: ulaD [H]

Synonym: PM1246

Alternate gene names: 15603111

Gene position: 1439809-1439165 (Counterclockwise)

Preceding gene: 15603112

Following gene: 15603110

Centisome position: 63.78

GC content: 44.81

Gene sequence:

>645_bases
ATGGCAAAACCACTTATTCAACTTGCACTAGATTCGCTTGATTTAGAAAGCGCGGTTGTCACCGCCAAAAATGCGGCTGA
TTCTGTCGACATTATTGAAGTCGGCACCATTCTTGCCTTTGCAGAAGGAATGCGCGCGGTCCGTACATTGCGCGCCTTGC
ACCCAGATCACATTTTAGTCTGTGATATGAAAACCACTGATGCAGGAGCAATTTTAGCGGAAATGGCATTCAAGGCAGGA
GCAGACTGGCTCACCGTTTCTGCCGCGGCTCACATTGCCACTATTGCGAGCTGTAAAAAAATTGCGGATAGTTACAACAA
AGAGATTCAAATTGAAATCTATGGTAACTGGACATTTGATGATGCAAAAGCGTGGGTTGATTTAGGCATCACACAAGCCA
TTTATCATCGTTCACGCGATGCGGAAGCAGCAGGCAAAGGTTGGAGCGAAGACGATCTGAACACGATGAAAAAACTGTCC
GATATCGGTCTGGCGCTTTCTATTACAGGCGGCATTGTCCCTGAAGATATTCATTTATTTAAAGAAATCAATGCTAAAGC
CTTCATTGCTGGCAGAGCCTTTACGGGTGAAGCGGGCAAATTAACTGCAGAAAAAGTGCGGTCAGAAATTAATAAATATT
GGTGA

Upstream 100 bases:

>100_bases
GAATCCGGCTTATTTTGCAGCTTACCAAGCTAAATATCAACGCTATCAACAACTTACTACTGCCTTAAAAGCAATGCTTT
AATTGATAATGAGGAACAAT

Downstream 100 bases:

>100_bases
TAATACAGAAATACGGAGCAAATAGTGAGAAAACATAAAATAGGGATTTATGAAAAAGCCCTCCCTAAAAATATAAGCTG
GCAAGATCGTCTCTCCATTG

Product: 3-keto-L-gulonate-6-phosphate decarboxylase

Products: NA

Alternate protein names: KGPDC; 3-dehydro-L-gulonate-6-phosphate decarboxylase [H]

Number of amino acids: Translated: 214; Mature: 213

Protein sequence:

>214_residues
MAKPLIQLALDSLDLESAVVTAKNAADSVDIIEVGTILAFAEGMRAVRTLRALHPDHILVCDMKTTDAGAILAEMAFKAG
ADWLTVSAAAHIATIASCKKIADSYNKEIQIEIYGNWTFDDAKAWVDLGITQAIYHRSRDAEAAGKGWSEDDLNTMKKLS
DIGLALSITGGIVPEDIHLFKEINAKAFIAGRAFTGEAGKLTAEKVRSEINKYW

Sequences:

>Translated_214_residues
MAKPLIQLALDSLDLESAVVTAKNAADSVDIIEVGTILAFAEGMRAVRTLRALHPDHILVCDMKTTDAGAILAEMAFKAG
ADWLTVSAAAHIATIASCKKIADSYNKEIQIEIYGNWTFDDAKAWVDLGITQAIYHRSRDAEAAGKGWSEDDLNTMKKLS
DIGLALSITGGIVPEDIHLFKEINAKAFIAGRAFTGEAGKLTAEKVRSEINKYW
>Mature_213_residues
AKPLIQLALDSLDLESAVVTAKNAADSVDIIEVGTILAFAEGMRAVRTLRALHPDHILVCDMKTTDAGAILAEMAFKAGA
DWLTVSAAAHIATIASCKKIADSYNKEIQIEIYGNWTFDDAKAWVDLGITQAIYHRSRDAEAAGKGWSEDDLNTMKKLSD
IGLALSITGGIVPEDIHLFKEINAKAFIAGRAFTGEAGKLTAEKVRSEINKYW

Specific function: Catalyzes the decarboxylation of 3-keto-L-gulonate-6-P into L-xylulose-5-P [H]

COG id: COG0269

COG function: function code G; 3-hexulose-6-phosphate synthase and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPS/KGPDC family. KGPDC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790006, Length=215, Percent_Identity=52.5581395348837, Blast_Score=218, Evalue=2e-58,
Organism=Escherichia coli, GI1790640, Length=215, Percent_Identity=46.046511627907, Blast_Score=198, Evalue=2e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001754
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00215 OMPdecase [H]

EC number: =4.1.1.85 [H]

Molecular weight: Translated: 23136; Mature: 23004

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKPLIQLALDSLDLESAVVTAKNAADSVDIIEVGTILAFAEGMRAVRTLRALHPDHILV
CCCHHHHHHHHHCCHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
CDMKTTDAGAILAEMAFKAGADWLTVSAAAHIATIASCKKIADSYNKEIQIEIYGNWTFD
EECCCCCHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCC
DAKAWVDLGITQAIYHRSRDAEAAGKGWSEDDLNTMKKLSDIGLALSITGGIVPEDIHLF
HHHHHHHHHHHHHHHHCCCCCHHHCCCCCHHHHHHHHHHHHCCEEEEECCCCCCHHHHHH
KEINAKAFIAGRAFTGEAGKLTAEKVRSEINKYW
HHCCCEEEEECCEECCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
AKPLIQLALDSLDLESAVVTAKNAADSVDIIEVGTILAFAEGMRAVRTLRALHPDHILV
CCHHHHHHHHHCCHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
CDMKTTDAGAILAEMAFKAGADWLTVSAAAHIATIASCKKIADSYNKEIQIEIYGNWTFD
EECCCCCHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCC
DAKAWVDLGITQAIYHRSRDAEAAGKGWSEDDLNTMKKLSDIGLALSITGGIVPEDIHLF
HHHHHHHHHHHHHHHHCCCCCHHHCCCCCHHHHHHHHHHHHCCEEEEECCCCCCHHHHHH
KEINAKAFIAGRAFTGEAGKLTAEKVRSEINKYW
HHCCCEEEEECCEECCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 9274005 [H]