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The map label for this gene is ybhA [H]

Identifier: 15603108

GI number: 15603108

Start: 1436717

End: 1437532

Strand: Direct

Name: ybhA [H]

Synonym: PM1243

Alternate gene names: 15603108

Gene position: 1436717-1437532 (Clockwise)

Preceding gene: 15603106

Following gene: 15603122

Centisome position: 63.64

GC content: 43.5

Gene sequence:

>816_bases
ATGAAATATCAAGTCATTGCATTTGATCTTGATGGCACCTTATTAAATCGCCAAGGTCAAATTCTTCCCACCAGTAAAAA
AATCATTCAGCATTGTCTGGATAAAGGGCTCAAAGTCATGCTCGTGACCGGGCGACACCACACTGCAGCATACCCTTATT
ATCATGAACTGAATTTAACCACACCGATGATTTGTTGTAATGGGACTTATGTTTACCAACCACAAACCGATCAAGTGCTC
AGTGCAAACCCGCTTTCTTTATCGCAAGCGAAAACAGTAGTGCAACTGGCTGAAAAGTATGGGCTTCATTTACTCATGTA
TTCGCGTGATGCCATGAACTACGCTGTATTAAATGAACACATGAGAAAATTTTCTCAATGGGTCCAACATTGTCCTCCTC
ACGTACGCCCGCATTTATGTCAGGTTTCAGATTTCCACGCGTTGCTTGATGATAAGGAAACTATCTGGAAATTTGTGATC
AGTCATCCTGAACGTGACACAATGCTCAAGGCTATCCAAGCACTTTCGCCAACGGAGTTTAGTTGCGAATGGTCTTGGGT
TGATCGTGTTGATATCGCCAATGCAGGTAACACGAAAGGCGCCAGACTTTTAGAATTACTGAATTCCTGGCACATTGCAC
CTCAACATGTGATTGCGTTTGGGGATAATCATAACGATATCTCTATGTTAAGTGCAGTAGGGCTCGGTGTCGCAATGGGC
AATGCTGAAAACGAGGTTAAACAACAGGCGGATTTGATCACGTTGAGCAATGATCAAGACGGAATCGCGTCTGTCCTTGC
TACCGTTCTCGACTAA

Upstream 100 bases:

>100_bases
TGAATTTCTTGCTTGTCTATGAGGCTTGAAGATTCATTTTCTTTTTTTATTAAACACTCTATACTGTATTAAGTAACTTA
TATTCAATACAGGAAAAAAG

Downstream 100 bases:

>100_bases
TCACCTTTTAAGGATAAAGAGCTAAAGTACCTCCTTTAGCTCTTTTGCTTAGTGCGTTTTATTGCCCGTAATACGCGTTT
TTCCCATGTTTACGTAAGTA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MKYQVIAFDLDGTLLNRQGQILPTSKKIIQHCLDKGLKVMLVTGRHHTAAYPYYHELNLTTPMICCNGTYVYQPQTDQVL
SANPLSLSQAKTVVQLAEKYGLHLLMYSRDAMNYAVLNEHMRKFSQWVQHCPPHVRPHLCQVSDFHALLDDKETIWKFVI
SHPERDTMLKAIQALSPTEFSCEWSWVDRVDIANAGNTKGARLLELLNSWHIAPQHVIAFGDNHNDISMLSAVGLGVAMG
NAENEVKQQADLITLSNDQDGIASVLATVLD

Sequences:

>Translated_271_residues
MKYQVIAFDLDGTLLNRQGQILPTSKKIIQHCLDKGLKVMLVTGRHHTAAYPYYHELNLTTPMICCNGTYVYQPQTDQVL
SANPLSLSQAKTVVQLAEKYGLHLLMYSRDAMNYAVLNEHMRKFSQWVQHCPPHVRPHLCQVSDFHALLDDKETIWKFVI
SHPERDTMLKAIQALSPTEFSCEWSWVDRVDIANAGNTKGARLLELLNSWHIAPQHVIAFGDNHNDISMLSAVGLGVAMG
NAENEVKQQADLITLSNDQDGIASVLATVLD
>Mature_271_residues
MKYQVIAFDLDGTLLNRQGQILPTSKKIIQHCLDKGLKVMLVTGRHHTAAYPYYHELNLTTPMICCNGTYVYQPQTDQVL
SANPLSLSQAKTVVQLAEKYGLHLLMYSRDAMNYAVLNEHMRKFSQWVQHCPPHVRPHLCQVSDFHALLDDKETIWKFVI
SHPERDTMLKAIQALSPTEFSCEWSWVDRVDIANAGNTKGARLLELLNSWHIAPQHVIAFGDNHNDISMLSAVGLGVAMG
NAENEVKQQADLITLSNDQDGIASVLATVLD

Specific function: Catalyzes the dephosphorylation of the artificial chromogenic substrate p-nitrophenyl phosphate (pNPP) and of the natural substrates pyridoxalphosphate and erythrose 4-phosphate [H]

COG id: COG0561

COG function: function code R; Predicted hydrolases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. Cof family [H]

Homologues:

Organism=Escherichia coli, GI1786982, Length=269, Percent_Identity=40.5204460966543, Blast_Score=217, Evalue=8e-58,
Organism=Escherichia coli, GI2367265, Length=275, Percent_Identity=28.3636363636364, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787043, Length=279, Percent_Identity=25.089605734767, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001757
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006379
- InterPro:   IPR000150
- InterPro:   IPR006380 [H]

Pfam domain/function: PF00702 Hydrolase; PF05116 S6PP [H]

EC number: NA

Molecular weight: Translated: 30431; Mature: 30431

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: PS01228 COF_1 ; PS01229 COF_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYQVIAFDLDGTLLNRQGQILPTSKKIIQHCLDKGLKVMLVTGRHHTAAYPYYHELNLT
CCEEEEEEECCCEEECCCCCEECCHHHHHHHHHHCCCEEEEEECCCCCEECCEEEECCCC
TPMICCNGTYVYQPQTDQVLSANPLSLSQAKTVVQLAEKYGLHLLMYSRDAMNYAVLNEH
CCEEEECCEEEECCCCCCEECCCCCCHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHH
MRKFSQWVQHCPPHVRPHLCQVSDFHALLDDKETIWKFVISHPERDTMLKAIQALSPTEF
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCC
SCEWSWVDRVDIANAGNTKGARLLELLNSWHIAPQHVIAFGDNHNDISMLSAVGLGVAMG
CEEEEEECCEEECCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHEEC
NAENEVKQQADLITLSNDQDGIASVLATVLD
CCHHHHHHHHCEEEECCCCHHHHHHHHHHCC
>Mature Secondary Structure
MKYQVIAFDLDGTLLNRQGQILPTSKKIIQHCLDKGLKVMLVTGRHHTAAYPYYHELNLT
CCEEEEEEECCCEEECCCCCEECCHHHHHHHHHHCCCEEEEEECCCCCEECCEEEECCCC
TPMICCNGTYVYQPQTDQVLSANPLSLSQAKTVVQLAEKYGLHLLMYSRDAMNYAVLNEH
CCEEEECCEEEECCCCCCEECCCCCCHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHH
MRKFSQWVQHCPPHVRPHLCQVSDFHALLDDKETIWKFVISHPERDTMLKAIQALSPTEF
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCC
SCEWSWVDRVDIANAGNTKGARLLELLNSWHIAPQHVIAFGDNHNDISMLSAVGLGVAMG
CEEEEEECCEEECCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHEEC
NAENEVKQQADLITLSNDQDGIASVLATVLD
CCHHHHHHHHCEEEECCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7665460; 8564363; 8905232; 9278503 [H]