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The map label for this gene is gcp [H]

Identifier: 15603103

GI number: 15603103

Start: 1429170

End: 1430201

Strand: Reverse

Name: gcp [H]

Synonym: PM1238

Alternate gene names: 15603103

Gene position: 1430201-1429170 (Counterclockwise)

Preceding gene: 15603107

Following gene: 15603102

Centisome position: 63.35

GC content: 45.64

Gene sequence:

>1032_bases
ATGCGCGTGTTAGGCATTGAAACCTCCTGTGATGAAACAGGGGTCGCGATTTATGATGAAGAAAAAGGTTTAGTGGCAAA
CCAGTTATACACACAAATTGCTTTACATGCTGATTACGGCGGGGTCGTGCCCGAATTAGCATCGCGCGATCATATTCGAA
AAACCGCTCCTTTGATCCAAGCGGCGTTAGCACAAGCTAATTTAACGCCCGACGAGATCGATGGGATCGCGTATACCTCT
GGTCCAGGCTTAGTCGGTGCATTATTAGTGGGATCCACTATTGCACGCTCTTTAGCTTATGCTTGGAATGTGCCAGCTAT
TGGTGTACACCATATGGAAGGGCATTTGCTAGCACCAATGTTGGAAGATAATCCACCGACATTCCCTTTTGTTGCGTTAT
TAGTCTCAGGGGGACACACGCAATTAGTCCGTGTCGATGGCGTAGGACGTTATCAGTTACTGGGTGAATCAATTGATGAT
GCGGCAGGCGAAGCCTTTGATAAAACAGCGAAATTATTAGGCTTAGATTATCCGGGTGGTGCCGCGTTGGCGCGTTTGGC
GGAAAAAGGTGATCCTAAACGTTTTAAGTTTCCACGTCCGATGACGGATCGTCCAGGTTTGGATTTTAGTTTCTCCGGTT
TAAAAACCTTTGCTGCCAATACACTGCAGCAAGCGATAAAAGAAGAAGGGGAATTAACCGAACAAACCAAAGCAGATATT
GCCTATGCTTTCCAACAAGCTGTGGTTGAAACTTTAGTGATTAAATGCCGCCGTGCGTTAAAAGAAACGGGATTTAACCG
CCTCGTGATTGCGGGGGGCGTAAGTGCAAATAAGCAACTTCGTCAGGATTTAGCACAATTAATGCAGCAGTTAAAAGGGG
AAGTATTTTATCCACAACCACAATTTTGTACCGATAATGGAGCCATGATTGCCTATACTGGTTTTTTACGTTTAAAACAA
GGGGAGTCACAACCGCTTGCGATTCAGGTAAAGCCGCGTTGGGCGATGACTGAGCTTTCTGCGATTGATTAA

Upstream 100 bases:

>100_bases
GAAGTTTGATCTTTTGTGTAAAAATGCGCTGTCAAACTGGTGAAAGCGTGTTAAACAAGGTAAAATTCTGCCCCAATAAT
AATGACAAAGGAAGAGCAAA

Downstream 100 bases:

>100_bases
TATTTAACAAGGAAATCACCATGAGTGAACAGCTAAAAATAAAAGCCATGCGTGCAGCAGGTGTGGGTTGTGTCTTAATG
TTAATGATAATTGCCTTAGT

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MRVLGIETSCDETGVAIYDEEKGLVANQLYTQIALHADYGGVVPELASRDHIRKTAPLIQAALAQANLTPDEIDGIAYTS
GPGLVGALLVGSTIARSLAYAWNVPAIGVHHMEGHLLAPMLEDNPPTFPFVALLVSGGHTQLVRVDGVGRYQLLGESIDD
AAGEAFDKTAKLLGLDYPGGAALARLAEKGDPKRFKFPRPMTDRPGLDFSFSGLKTFAANTLQQAIKEEGELTEQTKADI
AYAFQQAVVETLVIKCRRALKETGFNRLVIAGGVSANKQLRQDLAQLMQQLKGEVFYPQPQFCTDNGAMIAYTGFLRLKQ
GESQPLAIQVKPRWAMTELSAID

Sequences:

>Translated_343_residues
MRVLGIETSCDETGVAIYDEEKGLVANQLYTQIALHADYGGVVPELASRDHIRKTAPLIQAALAQANLTPDEIDGIAYTS
GPGLVGALLVGSTIARSLAYAWNVPAIGVHHMEGHLLAPMLEDNPPTFPFVALLVSGGHTQLVRVDGVGRYQLLGESIDD
AAGEAFDKTAKLLGLDYPGGAALARLAEKGDPKRFKFPRPMTDRPGLDFSFSGLKTFAANTLQQAIKEEGELTEQTKADI
AYAFQQAVVETLVIKCRRALKETGFNRLVIAGGVSANKQLRQDLAQLMQQLKGEVFYPQPQFCTDNGAMIAYTGFLRLKQ
GESQPLAIQVKPRWAMTELSAID
>Mature_343_residues
MRVLGIETSCDETGVAIYDEEKGLVANQLYTQIALHADYGGVVPELASRDHIRKTAPLIQAALAQANLTPDEIDGIAYTS
GPGLVGALLVGSTIARSLAYAWNVPAIGVHHMEGHLLAPMLEDNPPTFPFVALLVSGGHTQLVRVDGVGRYQLLGESIDD
AAGEAFDKTAKLLGLDYPGGAALARLAEKGDPKRFKFPRPMTDRPGLDFSFSGLKTFAANTLQQAIKEEGELTEQTKADI
AYAFQQAVVETLVIKCRRALKETGFNRLVIAGGVSANKQLRQDLAQLMQQLKGEVFYPQPQFCTDNGAMIAYTGFLRLKQ
GESQPLAIQVKPRWAMTELSAID

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=337, Percent_Identity=36.4985163204748, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI8923380, Length=327, Percent_Identity=33.6391437308869, Blast_Score=160, Evalue=2e-39,
Organism=Escherichia coli, GI1789445, Length=341, Percent_Identity=72.4340175953079, Blast_Score=524, Evalue=1e-150,
Organism=Caenorhabditis elegans, GI17557464, Length=330, Percent_Identity=32.4242424242424, Blast_Score=164, Evalue=7e-41,
Organism=Caenorhabditis elegans, GI71995670, Length=327, Percent_Identity=34.5565749235474, Blast_Score=151, Evalue=6e-37,
Organism=Saccharomyces cerevisiae, GI6320099, Length=376, Percent_Identity=34.8404255319149, Blast_Score=184, Evalue=2e-47,
Organism=Saccharomyces cerevisiae, GI6322891, Length=349, Percent_Identity=30.945558739255, Blast_Score=133, Evalue=5e-32,
Organism=Drosophila melanogaster, GI20129063, Length=342, Percent_Identity=35.9649122807018, Blast_Score=200, Evalue=1e-51,
Organism=Drosophila melanogaster, GI21357207, Length=335, Percent_Identity=31.3432835820896, Blast_Score=167, Evalue=7e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 37067; Mature: 37067

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLGIETSCDETGVAIYDEEKGLVANQLYTQIALHADYGGVVPELASRDHIRKTAPLIQ
CEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHEEECCCCCCCHHHHCHHHHHHHHHHHH
AALAQANLTPDEIDGIAYTSGPGLVGALLVGSTIARSLAYAWNVPAIGVHHMEGHLLAPM
HHHHHCCCCHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEECCC
LEDNPPTFPFVALLVSGGHTQLVRVDGVGRYQLLGESIDDAAGEAFDKTAKLLGLDYPGG
CCCCCCCHHHHHHHHCCCCEEEEEECCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCH
AALARLAEKGDPKRFKFPRPMTDRPGLDFSFSGLKTFAANTLQQAIKEEGELTEQTKADI
HHHHHHHHCCCCCCEECCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
AYAFQQAVVETLVIKCRRALKETGFNRLVIAGGVSANKQLRQDLAQLMQQLKGEVFYPQP
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCEECCCC
QFCTDNGAMIAYTGFLRLKQGESQPLAIQVKPRWAMTELSAID
CCCCCCCCEEEEEEEEEEECCCCCCEEEEECCCHHHHHHHCCC
>Mature Secondary Structure
MRVLGIETSCDETGVAIYDEEKGLVANQLYTQIALHADYGGVVPELASRDHIRKTAPLIQ
CEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHEEECCCCCCCHHHHCHHHHHHHHHHHH
AALAQANLTPDEIDGIAYTSGPGLVGALLVGSTIARSLAYAWNVPAIGVHHMEGHLLAPM
HHHHHCCCCHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEECCC
LEDNPPTFPFVALLVSGGHTQLVRVDGVGRYQLLGESIDDAAGEAFDKTAKLLGLDYPGG
CCCCCCCHHHHHHHHCCCCEEEEEECCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCH
AALARLAEKGDPKRFKFPRPMTDRPGLDFSFSGLKTFAANTLQQAIKEEGELTEQTKADI
HHHHHHHHCCCCCCEECCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
AYAFQQAVVETLVIKCRRALKETGFNRLVIAGGVSANKQLRQDLAQLMQQLKGEVFYPQP
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCEECCCC
QFCTDNGAMIAYTGFLRLKQGESQPLAIQVKPRWAMTELSAID
CCCCCCCCEEEEEEEEEEECCCCCCEEEEECCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA