| Definition | Pasteurella multocida subsp. multocida str. Pm70, complete genome. |
|---|---|
| Accession | NC_002663 |
| Length | 2,257,487 |
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The map label for this gene is ponA [H]
Identifier: 15603095
GI number: 15603095
Start: 1420199
End: 1422760
Strand: Direct
Name: ponA [H]
Synonym: PM1230
Alternate gene names: 15603095
Gene position: 1420199-1422760 (Clockwise)
Preceding gene: 15603086
Following gene: 15603097
Centisome position: 62.91
GC content: 42.7
Gene sequence:
>2562_bases ATGCGGATCGCAAAACTAATACTCAGTACCCTGCTCACGCTCATCGTACTAGGCTGTCTCGCGCTAGGTGCGATCTATGT TTATTTAAAGGCGGACTTACCGGATGTAGAAAGCCTAAAAACAGTCGAATTACAACAGCCAATGCAAATTTATACGGCTG ATGGCAAACTGATTGGCGAAGTGGGAGAACAACGTCGGATTCCAGTGCCACTGGATAAAATTCCAAAACAACTGATTCAT GCTGTTTTAGCAACAGAAGATAACCGTTTCTATGAACATCATGGGCTCGATCCTATTGGCATTGCGCGTGCTATTATGGT CGCGGTTACGAAGAAAGGCGTTTCACAAGGCGCCAGTACAATTACTCAACAATTAGCACGAAATTTTTTCTTAACCCCTG AAAAATCGCTTGAACGCAAAGCTAAAGAAGCCGTTTTAGCCATTGATATCGAAAATACACTAAGTAAAAATGAGATTTTA GAACTCTATCTGAACAAAATTTATTTAGGCTATCGTTCTTATGGCGTTGCCGCTGCCGCCAAAACCTATTTTGGCAAAGA GCTCGATCAACTAAGCTTGTCCGAAATTGCGATTATCGCTGGCTTACCTAAAGCACCTTCCACAATGAACCCGATTTATT CATTAAAACGGGCGCAAGAACGCCGTAATATTGTCTTAGGACGGATGTTAACCACTAAATACATCACACAAGAAGAATAT GACGCGGCAATCAAAGAACCTATCGTCGCGCGCTACCATGGTGCACAAATTGATTTCCGTGCAGACTATGTCACTGAAAT GGCACGTCAAGAAATGGTCAGACGTTTTGGTGAAGAAAAAGCCTACACTAGCGGTTTTAAAGTTTATACTACGGTGCTTT CGAAGGATCAGGCTGAAGCGCAAAAAGCCTTACGTAATAACTTAATTGATTACGATATGCGCCATGGTTATCGTGGCGGT GCGCCACTTTGGCAAAAAGACGAAACGGTGTGGGACAATGATCGTATCATAGGTTTCTTAAAAAAATTACCACATTCTGA ACCGCTCTTACCGGCTGCCGTCATGAATATCAGCAAAACCGGAGCAGAACTTCTTCTAGCCTCAGGTGAACGCATGACCT TATCACACAATGCTATGCGTTGGGCGGGTAAAAAAACACCAAAAGTAGGCGAACAAATTTGGATTCGTCAAAAAGAGAAA GGGGAATGGATTCTGGCTCAAGTGCCGGAAGTCAACTCTGCCTTGGTATCCTTAAATAGTGATAATGGTGCAATTGAAGC CTTAGTTGGTGGATTTAGTTTCGAACAAAGCAAATTTAACCGTGCTACACAATCTTTAGTCCAAGTGGGCTCTTCAATTA AACCGTTTATTTATGCGGCCGCATTAGAAAAAGGGTTAACGCTTTCAAGCGTCTTACAAGACTCGCCTCTTGTCATACAA AAAGCAGGACAAAAACCTTGGCAGCCAAAAAACTCACCAAATCGATTTGATGGACCAATGCGCTTGCGGGTTGGCTTAGG ATTATCAAAAAATATGATTGCGATTCGTGCGATGCAAATGGCGGGCATTGATTTTACAGCAGAATTCTTACAACGCTTTG GTTTTAAACGCGATCAATACTTAGCCAGTGAAGCCCTTGCCTTAGGTGCGGCCTCTTTTACTCCACTTGAAATGGCAAGA GGCTACGCGGTCTTTGACAATGGCGGTTTCTTAGTTGATCCCTTTATTATTAATCGTATTTTAGACAATACGGGCAAAGA GATTTTCTTAGCCAATCCGAAAATTGCCTGTATTAGCTGTCATAATATTCCTGTGCTCTATGGTGAAACTGAAAAACTGG ATGCATTTAAAAACTACGACTTAAGCTTAACGGAGAATTTCGATACCAATATCAATGGGGAAGAAGAAAACGATGTCGGT GATTTGATCCCTGACTTGCCAGAACTTCAACCAACGGCACAAACACAATTAGATGAAAATAATCTTAGCTTTATGGCTGC GGCTAAAACAGATAATGCTGAAACCCAATATGCACCGCGCGTGATTAGCGGTGAATTGGCCTTTTTAGTTCGCAGTGCTT TAACCTCCGCTATTTATGGCGAGCCGGGTAAAAGCTGGGTGGGGACTAGCTGGCGCTTATCTAAAGCCTTTAAACGTCAA GATATCGGTGGAAAAACCGGTACTACGAATAATTCGAAAGTTGCTTGGTACGCTGGCTTTGGCGCACATTTAACCACCGC TGTGTATGTTGGCTTCGACGACAATAAGCGTAATTTAGGGCGCGGCGAAGCAGGGGCAAAAACGGCTTTACCTGCGTGGC AAGCCTATATGCAAGTAAGCTTAGAAAATATTCCAGAACGTAAATTGAGTCCACCACCCAATATTATTGAAAAACGCATT GATACGGGTTCTGGCTTACTCACGGAATCTGGTGGACGAATGGAATATTTTATCAATGGTACAGAACCTAAACGGAGTTA TGTAGAAGAACAAGGCTACTACATCCCATCTGATGAGATAAACGAAAATTCCCCAATCCAAGAACGGGAAGAACTTTTCT AA
Upstream 100 bases:
>100_bases ACTGCACTTTTAGCTTTGGATTTAGTCTTGTTGTCTTTATACTGTGTACAATTTTTTCGAGTTTTGAATAAACAAACATT AAACTAAAGAGAATTTCCCG
Downstream 100 bases:
>100_bases AACAGACCGCACTTTTAAGACGCTATTTCTTTCAAATAGCGTCTTGTGCAAACCACGCATTCAATAAACAGCTGACGCCT TCCACTAATTGTGTTTCACT
Product: PonA
Products: NA
Alternate protein names: PBP-1a; PBP1a; Penicillin-binding protein A; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Penicillin-sensitive transpeptidase; DD-transpeptidase [H]
Number of amino acids: Translated: 853; Mature: 853
Protein sequence:
>853_residues MRIAKLILSTLLTLIVLGCLALGAIYVYLKADLPDVESLKTVELQQPMQIYTADGKLIGEVGEQRRIPVPLDKIPKQLIH AVLATEDNRFYEHHGLDPIGIARAIMVAVTKKGVSQGASTITQQLARNFFLTPEKSLERKAKEAVLAIDIENTLSKNEIL ELYLNKIYLGYRSYGVAAAAKTYFGKELDQLSLSEIAIIAGLPKAPSTMNPIYSLKRAQERRNIVLGRMLTTKYITQEEY DAAIKEPIVARYHGAQIDFRADYVTEMARQEMVRRFGEEKAYTSGFKVYTTVLSKDQAEAQKALRNNLIDYDMRHGYRGG APLWQKDETVWDNDRIIGFLKKLPHSEPLLPAAVMNISKTGAELLLASGERMTLSHNAMRWAGKKTPKVGEQIWIRQKEK GEWILAQVPEVNSALVSLNSDNGAIEALVGGFSFEQSKFNRATQSLVQVGSSIKPFIYAAALEKGLTLSSVLQDSPLVIQ KAGQKPWQPKNSPNRFDGPMRLRVGLGLSKNMIAIRAMQMAGIDFTAEFLQRFGFKRDQYLASEALALGAASFTPLEMAR GYAVFDNGGFLVDPFIINRILDNTGKEIFLANPKIACISCHNIPVLYGETEKLDAFKNYDLSLTENFDTNINGEEENDVG DLIPDLPELQPTAQTQLDENNLSFMAAAKTDNAETQYAPRVISGELAFLVRSALTSAIYGEPGKSWVGTSWRLSKAFKRQ DIGGKTGTTNNSKVAWYAGFGAHLTTAVYVGFDDNKRNLGRGEAGAKTALPAWQAYMQVSLENIPERKLSPPPNIIEKRI DTGSGLLTESGGRMEYFINGTEPKRSYVEEQGYYIPSDEINENSPIQEREELF
Sequences:
>Translated_853_residues MRIAKLILSTLLTLIVLGCLALGAIYVYLKADLPDVESLKTVELQQPMQIYTADGKLIGEVGEQRRIPVPLDKIPKQLIH AVLATEDNRFYEHHGLDPIGIARAIMVAVTKKGVSQGASTITQQLARNFFLTPEKSLERKAKEAVLAIDIENTLSKNEIL ELYLNKIYLGYRSYGVAAAAKTYFGKELDQLSLSEIAIIAGLPKAPSTMNPIYSLKRAQERRNIVLGRMLTTKYITQEEY DAAIKEPIVARYHGAQIDFRADYVTEMARQEMVRRFGEEKAYTSGFKVYTTVLSKDQAEAQKALRNNLIDYDMRHGYRGG APLWQKDETVWDNDRIIGFLKKLPHSEPLLPAAVMNISKTGAELLLASGERMTLSHNAMRWAGKKTPKVGEQIWIRQKEK GEWILAQVPEVNSALVSLNSDNGAIEALVGGFSFEQSKFNRATQSLVQVGSSIKPFIYAAALEKGLTLSSVLQDSPLVIQ KAGQKPWQPKNSPNRFDGPMRLRVGLGLSKNMIAIRAMQMAGIDFTAEFLQRFGFKRDQYLASEALALGAASFTPLEMAR GYAVFDNGGFLVDPFIINRILDNTGKEIFLANPKIACISCHNIPVLYGETEKLDAFKNYDLSLTENFDTNINGEEENDVG DLIPDLPELQPTAQTQLDENNLSFMAAAKTDNAETQYAPRVISGELAFLVRSALTSAIYGEPGKSWVGTSWRLSKAFKRQ DIGGKTGTTNNSKVAWYAGFGAHLTTAVYVGFDDNKRNLGRGEAGAKTALPAWQAYMQVSLENIPERKLSPPPNIIEKRI DTGSGLLTESGGRMEYFINGTEPKRSYVEEQGYYIPSDEINENSPIQEREELF >Mature_853_residues MRIAKLILSTLLTLIVLGCLALGAIYVYLKADLPDVESLKTVELQQPMQIYTADGKLIGEVGEQRRIPVPLDKIPKQLIH AVLATEDNRFYEHHGLDPIGIARAIMVAVTKKGVSQGASTITQQLARNFFLTPEKSLERKAKEAVLAIDIENTLSKNEIL ELYLNKIYLGYRSYGVAAAAKTYFGKELDQLSLSEIAIIAGLPKAPSTMNPIYSLKRAQERRNIVLGRMLTTKYITQEEY DAAIKEPIVARYHGAQIDFRADYVTEMARQEMVRRFGEEKAYTSGFKVYTTVLSKDQAEAQKALRNNLIDYDMRHGYRGG APLWQKDETVWDNDRIIGFLKKLPHSEPLLPAAVMNISKTGAELLLASGERMTLSHNAMRWAGKKTPKVGEQIWIRQKEK GEWILAQVPEVNSALVSLNSDNGAIEALVGGFSFEQSKFNRATQSLVQVGSSIKPFIYAAALEKGLTLSSVLQDSPLVIQ KAGQKPWQPKNSPNRFDGPMRLRVGLGLSKNMIAIRAMQMAGIDFTAEFLQRFGFKRDQYLASEALALGAASFTPLEMAR GYAVFDNGGFLVDPFIINRILDNTGKEIFLANPKIACISCHNIPVLYGETEKLDAFKNYDLSLTENFDTNINGEEENDVG DLIPDLPELQPTAQTQLDENNLSFMAAAKTDNAETQYAPRVISGELAFLVRSALTSAIYGEPGKSWVGTSWRLSKAFKRQ DIGGKTGTTNNSKVAWYAGFGAHLTTAVYVGFDDNKRNLGRGEAGAKTALPAWQAYMQVSLENIPERKLSPPPNIIEKRI DTGSGLLTESGGRMEYFINGTEPKRSYVEEQGYYIPSDEINENSPIQEREELF
Specific function: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal
COG id: COG5009
COG function: function code M; Membrane carboxypeptidase/penicillin-binding protein
Gene ontology:
Cell location: Cell inner membrane; Single-pass type II membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI87082258, Length=866, Percent_Identity=52.7713625866051, Blast_Score=882, Evalue=0.0, Organism=Escherichia coli, GI1786343, Length=289, Percent_Identity=35.9861591695502, Blast_Score=156, Evalue=6e-39, Organism=Escherichia coli, GI1788867, Length=184, Percent_Identity=37.5, Blast_Score=114, Evalue=3e-26, Organism=Escherichia coli, GI1789601, Length=138, Percent_Identity=40.5797101449275, Blast_Score=94, Evalue=5e-20,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR001264 - InterPro: IPR011816 - InterPro: IPR001460 [H]
Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: 2.4.2.-; 3.4.-.-
Molecular weight: Translated: 94759; Mature: 94759
Theoretical pI: Translated: 7.03; Mature: 7.03
Prosite motif: PS00013 PROKAR_LIPOPROTEIN
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 2.2 %Met (Translated Protein) 2.6 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 2.2 %Met (Mature Protein) 2.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRIAKLILSTLLTLIVLGCLALGAIYVYLKADLPDVESLKTVELQQPMQIYTADGKLIGE CHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCHHHHHCCCCEEEECCCHHHHH VGEQRRIPVPLDKIPKQLIHAVLATEDNRFYEHHGLDPIGIARAIMVAVTKKGVSQGAST CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH ITQQLARNFFLTPEKSLERKAKEAVLAIDIENTLSKNEILELYLNKIYLGYRSYGVAAAA HHHHHHHHCCCCCHHHHHHHHHHEEEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH KTYFGKELDQLSLSEIAIIAGLPKAPSTMNPIYSLKRAQERRNIVLGRMLTTKYITQEEY HHHHHHHHHHCCHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH DAAIKEPIVARYHGAQIDFRADYVTEMARQEMVRRFGEEKAYTSGFKVYTTVLSKDQAEA HHHHHCCHHHHCCCCEEEEHHHHHHHHHHHHHHHHHCCHHHHCCCCEEEHHHHCCCHHHH QKALRNNLIDYDMRHGYRGGAPLWQKDETVWDNDRIIGFLKKLPHSEPLLPAAVMNISKT HHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHC GAELLLASGERMTLSHNAMRWAGKKTPKVGEQIWIRQKEKGEWILAQVPEVNSALVSLNS CHHEEEECCCEEEEECCHHHHCCCCCCCCCHHHEEEECCCCCEEEEECCCCCCEEEEECC DNGAIEALVGGFSFEQSKFNRATQSLVQVGSSIKPFIYAAALEKGLTLSSVLQDSPLVIQ CCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHCCCCEEEE KAGQKPWQPKNSPNRFDGPMRLRVGLGLSKNMIAIRAMQMAGIDFTAEFLQRFGFKRDQY CCCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHEEHHHHCCCCHHHHHHHHHCCCHHHH LASEALALGAASFTPLEMARGYAVFDNGGFLVDPFIINRILDNTGKEIFLANPKIACISC HHHHHHHHCCCCCCHHHHHCCEEEEECCCEEECHHHHHHHHHCCCCEEEEECCCEEEEEE HNIPVLYGETEKLDAFKNYDLSLTENFDTNINGEEENDVGDLIPDLPELQPTAQTQLDEN CCCEEEECCCHHHHHHHCCCCEEECCCCCCCCCCCCCCHHHHCCCCCCCCCCHHHHCCCC NLSFMAAAKTDNAETQYAPRVISGELAFLVRSALTSAIYGEPGKSWVGTSWRLSKAFKRQ CCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH DIGGKTGTTNNSKVAWYAGFGAHLTTAVYVGFDDNKRNLGRGEAGAKTALPAWQAYMQVS CCCCCCCCCCCCEEEEEECCCCCEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHH LENIPERKLSPPPNIIEKRIDTGSGLLTESGGRMEYFINGTEPKRSYVEEQGYYIPSDEI HHHCCCCCCCCCHHHHHHHCCCCCCEEECCCCEEEEEEECCCHHHHHHHHCCCCCCCCCC NENSPIQEREELF CCCCCCHHHHHCC >Mature Secondary Structure MRIAKLILSTLLTLIVLGCLALGAIYVYLKADLPDVESLKTVELQQPMQIYTADGKLIGE CHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCHHHHHCCCCEEEECCCHHHHH VGEQRRIPVPLDKIPKQLIHAVLATEDNRFYEHHGLDPIGIARAIMVAVTKKGVSQGAST CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH ITQQLARNFFLTPEKSLERKAKEAVLAIDIENTLSKNEILELYLNKIYLGYRSYGVAAAA HHHHHHHHCCCCCHHHHHHHHHHEEEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH KTYFGKELDQLSLSEIAIIAGLPKAPSTMNPIYSLKRAQERRNIVLGRMLTTKYITQEEY HHHHHHHHHHCCHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH DAAIKEPIVARYHGAQIDFRADYVTEMARQEMVRRFGEEKAYTSGFKVYTTVLSKDQAEA HHHHHCCHHHHCCCCEEEEHHHHHHHHHHHHHHHHHCCHHHHCCCCEEEHHHHCCCHHHH QKALRNNLIDYDMRHGYRGGAPLWQKDETVWDNDRIIGFLKKLPHSEPLLPAAVMNISKT HHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHC GAELLLASGERMTLSHNAMRWAGKKTPKVGEQIWIRQKEKGEWILAQVPEVNSALVSLNS CHHEEEECCCEEEEECCHHHHCCCCCCCCCHHHEEEECCCCCEEEEECCCCCCEEEEECC DNGAIEALVGGFSFEQSKFNRATQSLVQVGSSIKPFIYAAALEKGLTLSSVLQDSPLVIQ CCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHCCCCEEEE KAGQKPWQPKNSPNRFDGPMRLRVGLGLSKNMIAIRAMQMAGIDFTAEFLQRFGFKRDQY CCCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHEEHHHHCCCCHHHHHHHHHCCCHHHH LASEALALGAASFTPLEMARGYAVFDNGGFLVDPFIINRILDNTGKEIFLANPKIACISC HHHHHHHHCCCCCCHHHHHCCEEEEECCCEEECHHHHHHHHHCCCCEEEEECCCEEEEEE HNIPVLYGETEKLDAFKNYDLSLTENFDTNINGEEENDVGDLIPDLPELQPTAQTQLDEN CCCEEEECCCHHHHHHHCCCCEEECCCCCCCCCCCCCCHHHHCCCCCCCCCCHHHHCCCC NLSFMAAAKTDNAETQYAPRVISGELAFLVRSALTSAIYGEPGKSWVGTSWRLSKAFKRQ CCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH DIGGKTGTTNNSKVAWYAGFGAHLTTAVYVGFDDNKRNLGRGEAGAKTALPAWQAYMQVS CCCCCCCCCCCCEEEEEECCCCCEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHH LENIPERKLSPPPNIIEKRIDTGSGLLTESGGRMEYFINGTEPKRSYVEEQGYYIPSDEI HHHCCCCCCCCCHHHHHHHCCCCCCEEECCCCEEEEEEECCCHHHHHHHHCCCCCCCCCC NENSPIQEREELF CCCCCCHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 1916268; 7542800; 7592463; 10675023 [H]