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The map label for this gene is pdxS

Identifier: 15603097

GI number: 15603097

Start: 1424316

End: 1425203

Strand: Direct

Name: pdxS

Synonym: PM1232

Alternate gene names: 15603097

Gene position: 1424316-1425203 (Clockwise)

Preceding gene: 15603095

Following gene: 15603098

Centisome position: 63.09

GC content: 46.73

Gene sequence:

>888_bases
ATGAATACGATTTTAGGTTCTGATACCGTCAAAAGAGGTATGGCACAAATGCAAAAAGGCGGTGTGATTATGGATGTGGT
GAATGCCGAACAAGCACGCATTGCCGAAGCGGCTGGTGCGGTTGCTGTCATGGCGTTAGAGCGAGTGCCTTCTGATATTC
GTGCGGCGGGCGGTGTCGCACGCATGGCAAATCCGAAAATTGTCAAAGAGGTGATGAATGCGGTATCAATTCCAGTCATG
GCGAAAGCTCGAATTGGGCATATCACCGAAGCCCGCGTGTTAGAGGCAATGGGTGTCGATTACATTGACGAGAGCGAAGT
ATTAACTCCTGCTGACGATGAATTTCATCTGTTAAAATGTGAATTTACTGTGCCGTTCGTATGTGGTTGCCGTGATTTAG
GCGAAGCATTACGCCGTATCGGTGAAGGTGCCTCAATGTTGCGCACCAAAGGTGAACCGGGCACAGGTAATATTGTGGAA
GCGGTACGTCATATACGTAAAGTCAATGCACAAATCCGCAAAGTCGTCGCCATGAACCATGATGAGCTCATGACCGAGGC
CAAAAATCTTAGCGCACCCTTTGAATTACTATTACAAATCAAAGCATTAGGTAAATTACCGGTAGTAAATTTTGCCGCAG
GTGGGGTGGCAACGCCAGCCGATGCTGCTTTGATGATGGAATTAGGTGCTGATGGCGTCTTTGTTGGTTCAGGAATTTTT
AAATCTGAACATCCTGAAAAATTCGCCAAAGCCATTGTACAGGCGACCACTCATTATCAAGATTATGATTTGATCGCCCG
TTTATCGGAAGAATTAGGCGAACCGATGAAAGGCATTGAGATTTCCCGCCTGCAACAACATGAAAGAATGCAAGAGCGTG
GCTGGTAA

Upstream 100 bases:

>100_bases
CATTAAATTTCTCTTTTTTGACACTTTTAATCATACCTAAATAAGCGCAAAAATAGCAGCAGTTTATACACAATAATACA
ATGATAAAAGGAGACAAAAT

Downstream 100 bases:

>100_bases
GTATGAAAGACTATTCACATTTACACATTGGCGTGTTAGCTCTGCAGGGAGCAGTAAGCGAACATTTGCGCCAAATTGAA
CAACTTGGTGCCAACGCCAG

Product: pyridoxal biosynthesis lyase PdxS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MNTILGSDTVKRGMAQMQKGGVIMDVVNAEQARIAEAAGAVAVMALERVPSDIRAAGGVARMANPKIVKEVMNAVSIPVM
AKARIGHITEARVLEAMGVDYIDESEVLTPADDEFHLLKCEFTVPFVCGCRDLGEALRRIGEGASMLRTKGEPGTGNIVE
AVRHIRKVNAQIRKVVAMNHDELMTEAKNLSAPFELLLQIKALGKLPVVNFAAGGVATPADAALMMELGADGVFVGSGIF
KSEHPEKFAKAIVQATTHYQDYDLIARLSEELGEPMKGIEISRLQQHERMQERGW

Sequences:

>Translated_295_residues
MNTILGSDTVKRGMAQMQKGGVIMDVVNAEQARIAEAAGAVAVMALERVPSDIRAAGGVARMANPKIVKEVMNAVSIPVM
AKARIGHITEARVLEAMGVDYIDESEVLTPADDEFHLLKCEFTVPFVCGCRDLGEALRRIGEGASMLRTKGEPGTGNIVE
AVRHIRKVNAQIRKVVAMNHDELMTEAKNLSAPFELLLQIKALGKLPVVNFAAGGVATPADAALMMELGADGVFVGSGIF
KSEHPEKFAKAIVQATTHYQDYDLIARLSEELGEPMKGIEISRLQQHERMQERGW
>Mature_295_residues
MNTILGSDTVKRGMAQMQKGGVIMDVVNAEQARIAEAAGAVAVMALERVPSDIRAAGGVARMANPKIVKEVMNAVSIPVM
AKARIGHITEARVLEAMGVDYIDESEVLTPADDEFHLLKCEFTVPFVCGCRDLGEALRRIGEGASMLRTKGEPGTGNIVE
AVRHIRKVNAQIRKVVAMNHDELMTEAKNLSAPFELLLQIKALGKLPVVNFAAGGVATPADAALMMELGADGVFVGSGIF
KSEHPEKFAKAIVQATTHYQDYDLIARLSEELGEPMKGIEISRLQQHERMQERGW

Specific function: Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring

COG id: COG0214

COG function: function code H; Pyridoxine biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxS/SNZ family

Homologues:

Organism=Saccharomyces cerevisiae, GI6323743, Length=290, Percent_Identity=57.5862068965517, Blast_Score=343, Evalue=2e-95,
Organism=Saccharomyces cerevisiae, GI6323996, Length=293, Percent_Identity=59.7269624573379, Blast_Score=341, Evalue=8e-95,
Organism=Saccharomyces cerevisiae, GI6321049, Length=293, Percent_Identity=59.7269624573379, Blast_Score=340, Evalue=1e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PDXS_PASMU (Q9CLJ6)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_246169.1
- ProteinModelPortal:   Q9CLJ6
- SMR:   Q9CLJ6
- GeneID:   1244579
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM1232
- NMPDR:   fig|272843.1.peg.1232
- HOGENOM:   HBG292342
- OMA:   ARMSDPD
- ProtClustDB:   PRK04180
- BioCyc:   PMUL272843:PM1232-MONOMER
- HAMAP:   MF_01824
- InterPro:   IPR013785
- InterPro:   IPR011060
- InterPro:   IPR001852
- Gene3D:   G3DSA:3.20.20.70
- PIRSF:   PIRSF029271
- TIGRFAMs:   TIGR00343

Pfam domain/function: PF01680 SOR_SNZ; SSF51366 RibP_bind_barrel

EC number: NA

Molecular weight: Translated: 31915; Mature: 31915

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS01235 PDXS_SNZ_1; PS51129 PDXS_SNZ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTILGSDTVKRGMAQMQKGGVIMDVVNAEQARIAEAAGAVAVMALERVPSDIRAAGGVA
CCCCCCHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHH
RMANPKIVKEVMNAVSIPVMAKARIGHITEARVLEAMGVDYIDESEVLTPADDEFHLLKC
HHCCHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEE
EFTVPFVCGCRDLGEALRRIGEGASMLRTKGEPGTGNIVEAVRHIRKVNAQIRKVVAMNH
EECCCHHCCCHHHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCH
DELMTEAKNLSAPFELLLQIKALGKLPVVNFAAGGVATPADAALMMELGADGVFVGSGIF
HHHHHHHHCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHCCCCEEECCCCC
KSEHPEKFAKAIVQATTHYQDYDLIARLSEELGEPMKGIEISRLQQHERMQERGW
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNTILGSDTVKRGMAQMQKGGVIMDVVNAEQARIAEAAGAVAVMALERVPSDIRAAGGVA
CCCCCCHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHH
RMANPKIVKEVMNAVSIPVMAKARIGHITEARVLEAMGVDYIDESEVLTPADDEFHLLKC
HHCCHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEE
EFTVPFVCGCRDLGEALRRIGEGASMLRTKGEPGTGNIVEAVRHIRKVNAQIRKVVAMNH
EECCCHHCCCHHHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCH
DELMTEAKNLSAPFELLLQIKALGKLPVVNFAAGGVATPADAALMMELGADGVFVGSGIF
HHHHHHHHCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHCCCCEEECCCCC
KSEHPEKFAKAIVQATTHYQDYDLIARLSEELGEPMKGIEISRLQQHERMQERGW
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100