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The map label for this gene is yidC

Identifier: 15603030

GI number: 15603030

Start: 1359418

End: 1361043

Strand: Direct

Name: yidC

Synonym: PM1165

Alternate gene names: 15603030

Gene position: 1359418-1361043 (Clockwise)

Preceding gene: 15603029

Following gene: 15603031

Centisome position: 60.22

GC content: 40.65

Gene sequence:

>1626_bases
ATGGACTCAAGACGTAGCCTGTTAGTCATCGCACTACTCTTCATTTCTTTTCTTGTTTATCAGCAATGGCAACTTGACTA
CCATACGCCAAAACCTGTTGCAACTGAACAAGTAAAAGTATCTTCTGATGTACCTGCAAGTTCTGCTTCTTCATCTTCGG
ATATTGCAACAACAGCACAAGCACAAGGTCGTATTATCACATTAGAAAATGATGTATTCCGTTTGGAAGTGGATACCTTA
GGGGGCGATGTTGTTCATTCTGAATTATTAAAATACGATGCAGAATTAAATTCCAATACCCCGTTTACGTTGTTAACCAA
CAAAGCAAATCATGTCTATATCGCACAAAGTGGTCTTGTTGGTAAAGACGGTATTGATACCAAAGCGGGACGTGCTAACT
ATCAGGTTGATGGCGATACGTTTAAATTAGCAGATGGGCAAAATGAACTTGCCGTGCCATTCGTGTTTGAGAAAGACGGC
GTGACTTTCCGTAAAATCTTTGTGTTAAAACGTGGTGCTTATGACATTGCGGTAAACTTTGAAATTGATAACCAAAGTGA
TAAAACTATCGAAGTTGAGCCTTATGGGCAATTACGTCATACTTTAGTTGAAGATACTGGTAACGTCGCGATGCCAACCT
ATACGGGTGGCGCTTATTCCTCGTCTGAAACCAACTATAAAAAATACAGTTTTGCAGACATGGAAAAAGCCAACTTGTCT
ATCTCAACCAAAGCTGGCTGGGTCGCTGTATTACAGCACTATTTCGTTTCGGCGTGGATCCCAAATCAAGATGCAGATAA
TCAGCTTTATAGCTTAACCGATAAAGCTAATAATTTGGCTTCGATTGGTTATCGTGGTCCAGTAACTGCAATTCCTGCTG
GTGCCAAAGAAACGATTCGCAGCTCCCTTTGGACTGGACCTAAGTTACAAGATCAAATGGCAACTGTCGCAAACCATTTA
GACTTAAGTGTGGACTATGGGTGGGCATGGTTTATTGCTAAACCGCTATTCTGGCTCTTAACCTTTATTCAAAGTATTGT
ACAAAACTGGGGGCTTGCGATTATTGGTGTGACTTTAGTGGTCAAAGCGATTTTATACCCACTTACTAAAGCACAATACA
CCTCCATGGCAAAAATGCGTATGTTACAGCCGAAACTGCAAGAAATGCGTGAACGTTTTGGTGAAGATCGTCAACGTATG
AGCCAAGAAATGATGAAACTTTATAAAGAAGAGAAAGTCAATCCATTAGGTGGCTGTTTACCTATTCTTCTGCAAATGCC
AATTTTCATCGCATTATACTGGACGTTCTTAGAAGCCGTTGAATTACGTCATGCACCATTCTTTGGTTGGATCCAAGACT
TATCGGCACAAGACCCGTATTATATCCTGCCGATCTTAATGGGTGCATCGATGTTCTTATTACAGAAAATGTCACCAACG
CCAGTGGCAGATCCAACACAACAGAAGATCATGAACTTCATGCCATTAATCTTTATGGTGTTCTTCTTGTGGTTCCCATC
AGGCTTGGTATTATACTGGTTAGTGTCTAACTTGATCACTATCGCTCAACAGCAATTGATTTATCGTGGCTTAGAGAAAA
AAGGGTTACACTCTCGCCATAAATAA

Upstream 100 bases:

>100_bases
GTTGGCTTACGCTAAAACGTATATTAAAATGTCATCCTTTAAACGCGGGTGGATACGATCCTGTTCCACCAAAGATCAAT
AACAAAAAAGAGAAAAAATA

Downstream 100 bases:

>100_bases
TTCAGTTGAATGAACATAAAAGGCATCAAGTTGGTGCCTTTTGTTTTATCAAAGTGCGGTCATTTTTAAGAGAGTTTTTA
TGAAAGAAACCATTGTTGCA

Product: putative inner membrane protein translocase component YidC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 541; Mature: 541

Protein sequence:

>541_residues
MDSRRSLLVIALLFISFLVYQQWQLDYHTPKPVATEQVKVSSDVPASSASSSSDIATTAQAQGRIITLENDVFRLEVDTL
GGDVVHSELLKYDAELNSNTPFTLLTNKANHVYIAQSGLVGKDGIDTKAGRANYQVDGDTFKLADGQNELAVPFVFEKDG
VTFRKIFVLKRGAYDIAVNFEIDNQSDKTIEVEPYGQLRHTLVEDTGNVAMPTYTGGAYSSSETNYKKYSFADMEKANLS
ISTKAGWVAVLQHYFVSAWIPNQDADNQLYSLTDKANNLASIGYRGPVTAIPAGAKETIRSSLWTGPKLQDQMATVANHL
DLSVDYGWAWFIAKPLFWLLTFIQSIVQNWGLAIIGVTLVVKAILYPLTKAQYTSMAKMRMLQPKLQEMRERFGEDRQRM
SQEMMKLYKEEKVNPLGGCLPILLQMPIFIALYWTFLEAVELRHAPFFGWIQDLSAQDPYYILPILMGASMFLLQKMSPT
PVADPTQQKIMNFMPLIFMVFFLWFPSGLVLYWLVSNLITIAQQQLIYRGLEKKGLHSRHK

Sequences:

>Translated_541_residues
MDSRRSLLVIALLFISFLVYQQWQLDYHTPKPVATEQVKVSSDVPASSASSSSDIATTAQAQGRIITLENDVFRLEVDTL
GGDVVHSELLKYDAELNSNTPFTLLTNKANHVYIAQSGLVGKDGIDTKAGRANYQVDGDTFKLADGQNELAVPFVFEKDG
VTFRKIFVLKRGAYDIAVNFEIDNQSDKTIEVEPYGQLRHTLVEDTGNVAMPTYTGGAYSSSETNYKKYSFADMEKANLS
ISTKAGWVAVLQHYFVSAWIPNQDADNQLYSLTDKANNLASIGYRGPVTAIPAGAKETIRSSLWTGPKLQDQMATVANHL
DLSVDYGWAWFIAKPLFWLLTFIQSIVQNWGLAIIGVTLVVKAILYPLTKAQYTSMAKMRMLQPKLQEMRERFGEDRQRM
SQEMMKLYKEEKVNPLGGCLPILLQMPIFIALYWTFLEAVELRHAPFFGWIQDLSAQDPYYILPILMGASMFLLQKMSPT
PVADPTQQKIMNFMPLIFMVFFLWFPSGLVLYWLVSNLITIAQQQLIYRGLEKKGLHSRHK
>Mature_541_residues
MDSRRSLLVIALLFISFLVYQQWQLDYHTPKPVATEQVKVSSDVPASSASSSSDIATTAQAQGRIITLENDVFRLEVDTL
GGDVVHSELLKYDAELNSNTPFTLLTNKANHVYIAQSGLVGKDGIDTKAGRANYQVDGDTFKLADGQNELAVPFVFEKDG
VTFRKIFVLKRGAYDIAVNFEIDNQSDKTIEVEPYGQLRHTLVEDTGNVAMPTYTGGAYSSSETNYKKYSFADMEKANLS
ISTKAGWVAVLQHYFVSAWIPNQDADNQLYSLTDKANNLASIGYRGPVTAIPAGAKETIRSSLWTGPKLQDQMATVANHL
DLSVDYGWAWFIAKPLFWLLTFIQSIVQNWGLAIIGVTLVVKAILYPLTKAQYTSMAKMRMLQPKLQEMRERFGEDRQRM
SQEMMKLYKEEKVNPLGGCLPILLQMPIFIALYWTFLEAVELRHAPFFGWIQDLSAQDPYYILPILMGASMFLLQKMSPT
PVADPTQQKIMNFMPLIFMVFFLWFPSGLVLYWLVSNLITIAQQQLIYRGLEKKGLHSRHK

Specific function: Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and indepe

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 1 subfamily

Homologues:

Organism=Homo sapiens, GI223718097, Length=193, Percent_Identity=29.0155440414508, Blast_Score=68, Evalue=3e-11,
Organism=Escherichia coli, GI1790140, Length=551, Percent_Identity=54.9909255898367, Blast_Score=610, Evalue=1e-176,
Organism=Drosophila melanogaster, GI24662345, Length=192, Percent_Identity=29.1666666666667, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21356443, Length=192, Percent_Identity=29.1666666666667, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OXAA_PASMU (Q9CLQ2)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_246102.1
- ProteinModelPortal:   Q9CLQ2
- SMR:   Q9CLQ2
- GeneID:   1244512
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM1165
- NMPDR:   fig|272843.1.peg.1165
- HOGENOM:   HBG507812
- OMA:   TYRGAAF
- ProtClustDB:   PRK01318
- BioCyc:   PMUL272843:PM1165-MONOMER
- HAMAP:   MF_01810
- InterPro:   IPR019998
- InterPro:   IPR001708
- PANTHER:   PTHR12428
- PRINTS:   PR00701
- PRINTS:   PR01900
- TIGRFAMs:   TIGR03593
- TIGRFAMs:   TIGR03592

Pfam domain/function: PF02096 60KD_IMP

EC number: NA

Molecular weight: Translated: 61006; Mature: 61006

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xe3c0f30)-; HASH(0xcffad80)-; HASH(0xc857dc4)-; HASH(0xe5244f4)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSRRSLLVIALLFISFLVYQQWQLDYHTPKPVATEQVKVSSDVPASSASSSSDIATTAQ
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCEEHH
AQGRIITLENDVFRLEVDTLGGDVVHSELLKYDAELNSNTPFTLLTNKANHVYIAQSGLV
CCCEEEEEECCEEEEEEECCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEEEECCCC
GKDGIDTKAGRANYQVDGDTFKLADGQNELAVPFVFEKDGVTFRKIFVLKRGAYDIAVNF
CCCCCCCCCCCCCEEECCCEEEEECCCCCEEEEEEEECCCCEEEEEEEEECCCEEEEEEE
EIDNQSDKTIEVEPYGQLRHTLVEDTGNVAMPTYTGGAYSSSETNYKKYSFADMEKANLS
EECCCCCCEEEECCCHHHHHHHHHCCCCEECCEECCCCCCCCCCCCCEEEECCCHHCCEE
ISTKAGWVAVLQHYFVSAWIPNQDADNQLYSLTDKANNLASIGYRGPVTAIPAGAKETIR
EECCCHHHHHHHHHHHHHCCCCCCCCCHHEEHHHHCCCCEECCCCCCCCCCCCCHHHHHH
SSLWTGPKLQDQMATVANHLDLSVDYGWAWFIAKPLFWLLTFIQSIVQNWGLAIIGVTLV
HHHCCCCCHHHHHHHHHHHCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
VKAILYPLTKAQYTSMAKMRMLQPKLQEMRERFGEDRQRMSQEMMKLYKEEKVNPLGGCL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
PILLQMPIFIALYWTFLEAVELRHAPFFGWIQDLSAQDPYYILPILMGASMFLLQKMSPT
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCEEEHHHHHHHHHHHHHCCCCC
PVADPTQQKIMNFMPLIFMVFFLWFPSGLVLYWLVSNLITIAQQQLIYRGLEKKGLHSRH
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
K
H
>Mature Secondary Structure
MDSRRSLLVIALLFISFLVYQQWQLDYHTPKPVATEQVKVSSDVPASSASSSSDIATTAQ
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCEEHH
AQGRIITLENDVFRLEVDTLGGDVVHSELLKYDAELNSNTPFTLLTNKANHVYIAQSGLV
CCCEEEEEECCEEEEEEECCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEEEECCCC
GKDGIDTKAGRANYQVDGDTFKLADGQNELAVPFVFEKDGVTFRKIFVLKRGAYDIAVNF
CCCCCCCCCCCCCEEECCCEEEEECCCCCEEEEEEEECCCCEEEEEEEEECCCEEEEEEE
EIDNQSDKTIEVEPYGQLRHTLVEDTGNVAMPTYTGGAYSSSETNYKKYSFADMEKANLS
EECCCCCCEEEECCCHHHHHHHHHCCCCEECCEECCCCCCCCCCCCCEEEECCCHHCCEE
ISTKAGWVAVLQHYFVSAWIPNQDADNQLYSLTDKANNLASIGYRGPVTAIPAGAKETIR
EECCCHHHHHHHHHHHHHCCCCCCCCCHHEEHHHHCCCCEECCCCCCCCCCCCCHHHHHH
SSLWTGPKLQDQMATVANHLDLSVDYGWAWFIAKPLFWLLTFIQSIVQNWGLAIIGVTLV
HHHCCCCCHHHHHHHHHHHCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
VKAILYPLTKAQYTSMAKMRMLQPKLQEMRERFGEDRQRMSQEMMKLYKEEKVNPLGGCL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
PILLQMPIFIALYWTFLEAVELRHAPFFGWIQDLSAQDPYYILPILMGASMFLLQKMSPT
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCEEEHHHHHHHHHHHHHCCCCC
PVADPTQQKIMNFMPLIFMVFFLWFPSGLVLYWLVSNLITIAQQQLIYRGLEKKGLHSRH
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
K
H

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11248100