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The map label for this gene is fis [H]

Identifier: 15602951

GI number: 15602951

Start: 1282342

End: 1282641

Strand: Reverse

Name: fis [H]

Synonym: PM1086

Alternate gene names: 15602951

Gene position: 1282641-1282342 (Counterclockwise)

Preceding gene: 15602952

Following gene: 15602950

Centisome position: 56.82

GC content: 36.33

Gene sequence:

>300_bases
ATGTTAGAACAACAACGTAATCCTGCTGATGCACTAACTGTATCAGTGTTAAATTCACAATCTCAAGTCACAAATAAACC
ATTGCGTGATTCTGTGAAACAAGCATTGAGAAATTATTTGTCGCAGTTAGATGGCCAAGATGTCAATGAGCTTTATGAAT
TAGTATTAGCAGAAGTTGAGCATCCTATGTTAGATATGGTTATGCAATATACACGTGGAAATCAAACTCGTGCAGCGACA
ATGTTAGGGATTAACCGTGGCACTTTACGTAAGAAATTAAAAAAGTACGGTATGGGTTAA

Upstream 100 bases:

>100_bases
CCCGTTTTTAGACAGGCTTTTAATGCAATTACTGATCCCAAAGAACAATTAATTGCTTTAGAAGGTTTTTTTAATTTGAT
TCTGATGGATAAAGAAAAAA

Downstream 100 bases:

>100_bases
CGGACCATTGTAGTATTTAAACTAGTTTTGGTTATAGAAGGGCGGACTTAGGTTCGCCTTTTTAATTTTCATTTCCTTTC
TTTTTCAAAACAATGATTTT

Product: DNA-binding protein Fis

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 99; Mature: 99

Protein sequence:

>99_residues
MLEQQRNPADALTVSVLNSQSQVTNKPLRDSVKQALRNYLSQLDGQDVNELYELVLAEVEHPMLDMVMQYTRGNQTRAAT
MLGINRGTLRKKLKKYGMG

Sequences:

>Translated_99_residues
MLEQQRNPADALTVSVLNSQSQVTNKPLRDSVKQALRNYLSQLDGQDVNELYELVLAEVEHPMLDMVMQYTRGNQTRAAT
MLGINRGTLRKKLKKYGMG
>Mature_99_residues
MLEQQRNPADALTVSVLNSQSQVTNKPLRDSVKQALRNYLSQLDGQDVNELYELVLAEVEHPMLDMVMQYTRGNQTRAAT
MLGINRGTLRKKLKKYGMG

Specific function: Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters [H]

COG id: COG2901

COG function: function code KL; Factor for inversion stimulation Fis, transcriptional activator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transcriptional regulatory fis family [H]

Homologues:

Organism=Escherichia coli, GI1789661, Length=98, Percent_Identity=80.6122448979592, Blast_Score=161, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005412
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197 [H]

Pfam domain/function: PF02954 HTH_8 [H]

EC number: NA

Molecular weight: Translated: 11223; Mature: 11223

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.1 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.1 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEQQRNPADALTVSVLNSQSQVTNKPLRDSVKQALRNYLSQLDGQDVNELYELVLAEVE
CCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHC
HPMLDMVMQYTRGNQTRAATMLGINRGTLRKKLKKYGMG
CHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MLEQQRNPADALTVSVLNSQSQVTNKPLRDSVKQALRNYLSQLDGQDVNELYELVLAEVE
CCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHC
HPMLDMVMQYTRGNQTRAATMLGINRGTLRKKLKKYGMG
CHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA