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The map label for this gene is corC

Identifier: 15602898

GI number: 15602898

Start: 1215479

End: 1216381

Strand: Reverse

Name: corC

Synonym: PM1033

Alternate gene names: 15602898

Gene position: 1216381-1215479 (Counterclockwise)

Preceding gene: 15602899

Following gene: 15602897

Centisome position: 53.88

GC content: 40.97

Gene sequence:

>903_bases
ATGGCTAACGAAGAACAATCAAATACTTACTCTACTGAATCTCACCAGAAAAAAAGTTTTTTTCAATCGCTGTTTGGGCG
CTTTTTCCAAGGTGAATTAAAAAATCGTGAAGAGCTGGTCGAAGTGATTCGCGATTCAGAGCAAAACGAGCTGATTGATC
AAAATACACGGGAGATGATAGAAGGTGTCATGGAAATCGCGGAATTACGCGTGCGTGACATTATGATCCCCCGCTCACAA
ATAGTATTTATTCACACGGATCAAAATTTAGATTCTTGTTTGGATACGATCATTGTGTCAGCACACTCGCGTTTCCCGGT
GATTACGGATGAGCGTGATAATATCGCAGGGATTCTACATGCGAAAGATTTGCTCCGCTTTTTACGTTCCAATGCGGAAG
AATTTGATTTAATGCCTTTATTACGTCCTGCGGTAATTGTGCCGGAAAGTAAGCGAGTTGATCGGATGCTCAAAGATTTC
CGTTCAGAACGTTTTCATATGGCGATCGTGGTTGATGAGTTTGGCGCAGTGTCTGGTTTGGTGACAATTGAAGATATTCT
TGAGCAAATTGTAGGGGATATTGAAGATGAATTCGATGAAGAAGAAATTGTCAATATTCGTCAGCTTTCTCGCCATACTT
ATGCGGTACGCGCTTTAACGGATATTGAAGACTTTAATCAACAGTTTAATACTCACTTTGCTGATGAAGAGGTGGATACC
ATTGGTGGGGTGGTCATGCAAGCCTTTGGTTACTTACCAAAACGCGGTGAAGAAATCACCATTGAGAATATCGGTTTTAA
AGTGACTTCTGCGGATAGTCGTCGTTTGATTCAATTACGCATTACTGTCACGGATGAGCAGTTAGCTGAAATTGAAAAAG
CCGAAGAACTAAAGGAAGATTAA

Upstream 100 bases:

>100_bases
TCGTTTTTTGCCCCACTGTCTAGGGGCTTTTTTTTGCTATTAAGCAGGAAATATGTTACTTTTCAACGGTCAATGTTGAC
GGAAACGTATTCAAAAATTT

Downstream 100 bases:

>100_bases
ACACGTCGATACGGAAGACGAGCACGAGTAAAGACTCGTGCTTCATTATTTAAAGAAGATGAAAAAAAAGATTTTTACTT
ATTTTATTGCGATTTTTTCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MANEEQSNTYSTESHQKKSFFQSLFGRFFQGELKNREELVEVIRDSEQNELIDQNTREMIEGVMEIAELRVRDIMIPRSQ
IVFIHTDQNLDSCLDTIIVSAHSRFPVITDERDNIAGILHAKDLLRFLRSNAEEFDLMPLLRPAVIVPESKRVDRMLKDF
RSERFHMAIVVDEFGAVSGLVTIEDILEQIVGDIEDEFDEEEIVNIRQLSRHTYAVRALTDIEDFNQQFNTHFADEEVDT
IGGVVMQAFGYLPKRGEEITIENIGFKVTSADSRRLIQLRITVTDEQLAEIEKAEELKED

Sequences:

>Translated_300_residues
MANEEQSNTYSTESHQKKSFFQSLFGRFFQGELKNREELVEVIRDSEQNELIDQNTREMIEGVMEIAELRVRDIMIPRSQ
IVFIHTDQNLDSCLDTIIVSAHSRFPVITDERDNIAGILHAKDLLRFLRSNAEEFDLMPLLRPAVIVPESKRVDRMLKDF
RSERFHMAIVVDEFGAVSGLVTIEDILEQIVGDIEDEFDEEEIVNIRQLSRHTYAVRALTDIEDFNQQFNTHFADEEVDT
IGGVVMQAFGYLPKRGEEITIENIGFKVTSADSRRLIQLRITVTDEQLAEIEKAEELKED
>Mature_299_residues
ANEEQSNTYSTESHQKKSFFQSLFGRFFQGELKNREELVEVIRDSEQNELIDQNTREMIEGVMEIAELRVRDIMIPRSQI
VFIHTDQNLDSCLDTIIVSAHSRFPVITDERDNIAGILHAKDLLRFLRSNAEEFDLMPLLRPAVIVPESKRVDRMLKDFR
SERFHMAIVVDEFGAVSGLVTIEDILEQIVGDIEDEFDEEEIVNIRQLSRHTYAVRALTDIEDFNQQFNTHFADEEVDTI
GGVVMQAFGYLPKRGEEITIENIGFKVTSADSRRLIQLRITVTDEQLAEIEKAEELKED

Specific function: Plays a role in the transport of magnesium and cobalt ions

COG id: COG4535

COG function: function code P; Putative Mg2+ and Co2+ transporter CorC

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains

Homologues:

Organism=Homo sapiens, GI310128564, Length=204, Percent_Identity=31.8627450980392, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI94681046, Length=194, Percent_Identity=33.5051546391753, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI40068055, Length=187, Percent_Identity=31.5508021390374, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI40068053, Length=187, Percent_Identity=31.5508021390374, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI157412263, Length=212, Percent_Identity=28.7735849056604, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1786879, Length=280, Percent_Identity=64.6428571428572, Blast_Score=355, Evalue=2e-99,
Organism=Escherichia coli, GI1788119, Length=228, Percent_Identity=32.8947368421053, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI145693175, Length=230, Percent_Identity=27.8260869565217, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI87082033, Length=263, Percent_Identity=28.5171102661597, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790664, Length=237, Percent_Identity=27.4261603375527, Blast_Score=88, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CORC_PASMU (Q9CM13)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_245970.1
- ProteinModelPortal:   Q9CM13
- SMR:   Q9CM13
- GeneID:   1244380
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM1033
- NMPDR:   fig|272843.1.peg.1033
- HOGENOM:   HBG673071
- OMA:   RSQIIFI
- ProtClustDB:   CLSK870340
- BioCyc:   PMUL272843:PM1033-MONOMER
- GO:   GO:0006810
- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170
- Gene3D:   G3DSA:3.30.465.10
- SMART:   SM00116

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC

EC number: NA

Molecular weight: Translated: 34684; Mature: 34552

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: PS51371 CBS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANEEQSNTYSTESHQKKSFFQSLFGRFFQGELKNREELVEVIRDSEQNELIDQNTREMI
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHCCHHHHHH
EGVMEIAELRVRDIMIPRSQIVFIHTDQNLDSCLDTIIVSAHSRFPVITDERDNIAGILH
HHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCEEECCCCCHHHHHH
AKDLLRFLRSNAEEFDLMPLLRPAVIVPESKRVDRMLKDFRSERFHMAIVVDEFGAVSGL
HHHHHHHHHCCCCHHCCHHHHCCEEECCCHHHHHHHHHHHHHCCEEEEEEEECCCCHHHH
VTIEDILEQIVGDIEDEFDEEEIVNIRQLSRHTYAVRALTDIEDFNQQFNTHFADEEVDT
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
IGGVVMQAFGYLPKRGEEITIENIGFKVTSADSRRLIQLRITVTDEQLAEIEKAEELKED
HHHHHHHHHCCCCCCCCEEEEEECCEEEECCCCCEEEEEEEEECHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ANEEQSNTYSTESHQKKSFFQSLFGRFFQGELKNREELVEVIRDSEQNELIDQNTREMI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHCCHHHHHH
EGVMEIAELRVRDIMIPRSQIVFIHTDQNLDSCLDTIIVSAHSRFPVITDERDNIAGILH
HHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCEEECCCCCHHHHHH
AKDLLRFLRSNAEEFDLMPLLRPAVIVPESKRVDRMLKDFRSERFHMAIVVDEFGAVSGL
HHHHHHHHHCCCCHHCCHHHHCCEEECCCHHHHHHHHHHHHHCCEEEEEEEECCCCHHHH
VTIEDILEQIVGDIEDEFDEEEIVNIRQLSRHTYAVRALTDIEDFNQQFNTHFADEEVDT
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
IGGVVMQAFGYLPKRGEEITIENIGFKVTSADSRRLIQLRITVTDEQLAEIEKAEELKED
HHHHHHHHHCCCCCCCCEEEEEECCEEEECCCCCEEEEEEEEECHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100