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The map label for this gene is tolA [H]

Identifier: 15602833

GI number: 15602833

Start: 1140827

End: 1141996

Strand: Reverse

Name: tolA [H]

Synonym: PM0968

Alternate gene names: 15602833

Gene position: 1141996-1140827 (Counterclockwise)

Preceding gene: 15602834

Following gene: 15602832

Centisome position: 50.59

GC content: 44.79

Gene sequence:

>1170_bases
GTGCAAAGTAAGCAGAACAATAAAGACATCAGTGCGGTTATTCTTTCCGTCATTTTGCACGCGATCTTATTTGGCTTATT
GATTTTAGGTTCCCTCTATCATCGGGTTGAAATTATGGGTGGCGGTGAAGGTGACAGCGAGGTGATGGGGGCGGTGATGG
TTGATACAGGCGCAGCTGCTCAAGAGTGGGGACGCCTTCAGCAACAGAAAAAAGGTCAAACCGATAAAGCGAAAAAAACG
GAACCTGTTATTGAAGAGAAACCTGTACAGCCAGATGAACAAGAGATCATTCGTCAGCAAGAAATTGAGAAGCAAAAAGC
GTTAGAAAAACAGAAAGAAATTGAACAACAAAAAGAAATTGAACGTCAAAAACAACTTGCTGAGCAGAAAAAGCAAGAAG
AACAAGCACGCTTGGCAGCATTAGAAAAACAAAAACAAGCAGAAGAAGCAAAAGCGAAGCAGCTAGCTGAAGCGGCAAAA
CTAAAGGCAGAAGCAGAAGCTAAACGCTTAGCTGCATTGGCTAAACAAGCAGAAGAAGAGGCAAAAGCGAAAGCAGCAGA
AGAAGCCAAACGTAAAGCGGAAAAAGCGAAGGCAGAGGCTGAGGCAAAAGCGAAAGTAGAGAAAGCGAAAGCAGAGGCTG
AGGCAAAAGTGAAGGCAGAGAAAGCCAAAGCAGAAGCGGAAGCGAAGGCCAAAGCAGAAAAAGCCAAAGCGGAAGCAAAA
GCAAAAGCTGAAAAAGCCAAAGCCGATGCGGAAGCTGCACAACGCAAAGCGAATCAAGCCGCACTGGATGATTTCTTTAG
TGGAGGAGATGTTGGTGGTGGCTCTGCAACGAGAGGATCAAATACGGATCGTCAGGGAAGCCAAGGAAGCGGTGCAGCAC
TGGGGGCTGGTGATGGTGGAAAAACAGGCGATCAATATGCCGGAGTAATTAAACGAGAAATTCAACGCAGATTTTTGAAA
GAGCCGAGTTTTGCAAATAAAGTTTGCGTCGTTGAAGTCGAGTTTTTACGGGATGGAACCATTGCAAATTATCGTCGAGT
ATCAGGACCTGATGATATTTGTCAAGCTGCGGTAAGTGCCGTGGCAAGGACGAAGAAAGTCCCGCCAGCACCAACAGATG
ATATCTATCAAAGATATAAGAAATCCCCAATTGAATTTAAATTAAGATAA

Upstream 100 bases:

>100_bases
TCCTTATGAAGAAGTGATCAAAGCACTCAACTTGCTTCATCTTGCAGGTATTAAATCTGTTGGATTAATGACAAACCCGA
TTTAATAAAAAGGCAATATT

Downstream 100 bases:

>100_bases
AGTTAGTATTGCCTTTTTGTTTATCGTAAATCAACGATAAAGGATTGGAAATGAAAAATAATAGGTGGTTCCAATGAAAT
TAGTCACCCGTATGTGGAGT

Product: cell envelope integrity inner membrane protein TolA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MQSKQNNKDISAVILSVILHAILFGLLILGSLYHRVEIMGGGEGDSEVMGAVMVDTGAAAQEWGRLQQQKKGQTDKAKKT
EPVIEEKPVQPDEQEIIRQQEIEKQKALEKQKEIEQQKEIERQKQLAEQKKQEEQARLAALEKQKQAEEAKAKQLAEAAK
LKAEAEAKRLAALAKQAEEEAKAKAAEEAKRKAEKAKAEAEAKAKVEKAKAEAEAKVKAEKAKAEAEAKAKAEKAKAEAK
AKAEKAKADAEAAQRKANQAALDDFFSGGDVGGGSATRGSNTDRQGSQGSGAALGAGDGGKTGDQYAGVIKREIQRRFLK
EPSFANKVCVVEVEFLRDGTIANYRRVSGPDDICQAAVSAVARTKKVPPAPTDDIYQRYKKSPIEFKLR

Sequences:

>Translated_389_residues
MQSKQNNKDISAVILSVILHAILFGLLILGSLYHRVEIMGGGEGDSEVMGAVMVDTGAAAQEWGRLQQQKKGQTDKAKKT
EPVIEEKPVQPDEQEIIRQQEIEKQKALEKQKEIEQQKEIERQKQLAEQKKQEEQARLAALEKQKQAEEAKAKQLAEAAK
LKAEAEAKRLAALAKQAEEEAKAKAAEEAKRKAEKAKAEAEAKAKVEKAKAEAEAKVKAEKAKAEAEAKAKAEKAKAEAK
AKAEKAKADAEAAQRKANQAALDDFFSGGDVGGGSATRGSNTDRQGSQGSGAALGAGDGGKTGDQYAGVIKREIQRRFLK
EPSFANKVCVVEVEFLRDGTIANYRRVSGPDDICQAAVSAVARTKKVPPAPTDDIYQRYKKSPIEFKLR
>Mature_389_residues
MQSKQNNKDISAVILSVILHAILFGLLILGSLYHRVEIMGGGEGDSEVMGAVMVDTGAAAQEWGRLQQQKKGQTDKAKKT
EPVIEEKPVQPDEQEIIRQQEIEKQKALEKQKEIEQQKEIERQKQLAEQKKQEEQARLAALEKQKQAEEAKAKQLAEAAK
LKAEAEAKRLAALAKQAEEEAKAKAAEEAKRKAEKAKAEAEAKAKVEKAKAEAEAKVKAEKAKAEAEAKAKAEKAKAEAK
AKAEKAKADAEAAQRKANQAALDDFFSGGDVGGGSATRGSNTDRQGSQGSGAALGAGDGGKTGDQYAGVIKREIQRRFLK
EPSFANKVCVVEVEFLRDGTIANYRRVSGPDDICQAAVSAVARTKKVPPAPTDDIYQRYKKSPIEFKLR

Specific function: Involved in the tonB-independent uptake of proteins [H]

COG id: COG3064

COG function: function code M; Membrane protein involved in colicin uptake

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014161 [H]

Pfam domain/function: PF06519 TolA [H]

EC number: NA

Molecular weight: Translated: 42197; Mature: 42197

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHCCCCCCCCHHHHHHHHCCCCCEECC
>Mature Secondary Structure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HHHHCCCCCCCCHHHHHHHHCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800; 8921895 [H]