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The map label for this gene is ribH [H]

Identifier: 15602596

GI number: 15602596

Start: 859937

End: 860410

Strand: Reverse

Name: ribH [H]

Synonym: PM0731

Alternate gene names: 15602596

Gene position: 860410-859937 (Counterclockwise)

Preceding gene: 15602598

Following gene: 15602595

Centisome position: 38.11

GC content: 45.15

Gene sequence:

>474_bases
ATGAAAGTATTAGAAGGTGCCGTGGCAGCGCCAAATGCCAAAATTGCGGTCGTGATTGCGCGCTTTAATAGCTTTATTAA
TGAAAGTTTACTTGAAGGTGCATTAGATGCGTTAAAACGTCTCGGACAAGTCAAAGAAGAAAATATTACGTTAGTTCGTG
TGCCGGGCGCGTATGAATTACCGTTAGTGGCTCGCCGTTTAGCAGAAAGTAAAAAATACGATGGGATTGTAGCATTAGGA
ACCGTTATTCGTGGTGGCACCGCGCATTTTGAGTATGTGGCGGGTGAGGCTAGCAGTGGATTAGGTCAAGTAGCAATGAA
TGCAGATATTCCCGTTGCGTTTGGCGTATTAACCACAGAGAACATTGAGCAAGCAATTGAGCGAGCTGGCACCAAAGCGG
GGAATAAAGGGGCGGAAGCTGCGTTAGTTGCTTTAGAAATGGTAAATTTATTAGCGCAAATTGACGCGGCGTAA

Upstream 100 bases:

>100_bases
TAGGATGACACTCAATAGAAAGATAACTACTGAACGAAGAAAAATTTTATGCTAAAATTCGCAACCGATTTTACCCATTA
ATTTTAGATTAGGAAAGAAT

Downstream 100 bases:

>100_bases
TTCAGATGACAGAACAAAAACATGAGAAAAAAATCTCGCCACGTCGTCGTGCGAGAGAATGTGCAGTACAAGCGTTATAT
TCTTGGTATGTGTCACAAAA

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain [H]

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MKVLEGAVAAPNAKIAVVIARFNSFINESLLEGALDALKRLGQVKEENITLVRVPGAYELPLVARRLAESKKYDGIVALG
TVIRGGTAHFEYVAGEASSGLGQVAMNADIPVAFGVLTTENIEQAIERAGTKAGNKGAEAALVALEMVNLLAQIDAA

Sequences:

>Translated_157_residues
MKVLEGAVAAPNAKIAVVIARFNSFINESLLEGALDALKRLGQVKEENITLVRVPGAYELPLVARRLAESKKYDGIVALG
TVIRGGTAHFEYVAGEASSGLGQVAMNADIPVAFGVLTTENIEQAIERAGTKAGNKGAEAALVALEMVNLLAQIDAA
>Mature_157_residues
MKVLEGAVAAPNAKIAVVIARFNSFINESLLEGALDALKRLGQVKEENITLVRVPGAYELPLVARRLAESKKYDGIVALG
TVIRGGTAHFEYVAGEASSGLGQVAMNADIPVAFGVLTTENIEQAIERAGTKAGNKGAEAALVALEMVNLLAQIDAA

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786617, Length=156, Percent_Identity=73.0769230769231, Blast_Score=234, Evalue=2e-63,
Organism=Saccharomyces cerevisiae, GI6324429, Length=143, Percent_Identity=34.965034965035, Blast_Score=94, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002180 [H]

Pfam domain/function: PF00885 DMRL_synthase [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 16357; Mature: 16357

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLEGAVAAPNAKIAVVIARFNSFINESLLEGALDALKRLGQVKEENITLVRVPGAYEL
CCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCEEEEECCCCCCH
PLVARRLAESKKYDGIVALGTVIRGGTAHFEYVAGEASSGLGQVAMNADIPVAFGVLTTE
HHHHHHHHHCCCCCCEEEEHHHHCCCCCCEEEECCCCCCCCCCEEECCCCCEEEEHCCHH
NIEQAIERAGTKAGNKGAEAALVALEMVNLLAQIDAA
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKVLEGAVAAPNAKIAVVIARFNSFINESLLEGALDALKRLGQVKEENITLVRVPGAYEL
CCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCEEEEECCCCCCH
PLVARRLAESKKYDGIVALGTVIRGGTAHFEYVAGEASSGLGQVAMNADIPVAFGVLTTE
HHHHHHHHHCCCCCCEEEEHHHHCCCCCCEEEECCCCCCCCCCEEECCCCCEEEEHCCHH
NIEQAIERAGTKAGNKGAEAALVALEMVNLLAQIDAA
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA