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The map label for this gene is nagC [H]

Identifier: 15602548

GI number: 15602548

Start: 792792

End: 794015

Strand: Reverse

Name: nagC [H]

Synonym: PM0683

Alternate gene names: 15602548

Gene position: 794015-792792 (Counterclockwise)

Preceding gene: 15602549

Following gene: 15602547

Centisome position: 35.17

GC content: 41.75

Gene sequence:

>1224_bases
ATGCGAGAAAATCACCAAATAGCAAATGTTGATTTAGTAAAACAAATGAATAGCGCTGTTGTTTATAAACTGATTGATCA
ACAAGGTCCCATTTCTCGTATTCAAATTTCAGAACTCAGCCAATTAGCCCCGGCGAGTGTCACTAAAATTACACGTCATC
TGCTTGCTCGAGGGTTAATTAAAGAAGTGGAGCAACAGGAGTCTACTGGTGGACGTCGTGCCACTTCAATTGTGGCGGAA
CATAAAGCTTTCCGCACGATTTTGATTCGTTTAGGTCGTCAACATGCGACTTTTGCTATCATGGATTTATCCACGAAGTT
ATTAAAAAAAGCTGTGGTGGATTTACCTGAACAGCAAAGTGTTACGAGTATAGAGGCTTTTCTGTTACAACATTTGACGG
CATTTATGGCACAACATCAGAAACGAGGCAGTGAGTTTATCGCGGTGGGGATCACTGTGCCGGGATTTGTCGATGTGAAA
ACGGACATGATTCAATATATGCCACATCTTGATTTAGACGCGCCTTGGGATCTGGCGAATAAAATCTCACAACATACGCA
GTTAGCCACTTTTATTGGACATGATGTGCGCAGTTTAGCCTTAGCGGAACATTATTTTGGTGTGACGCAAGATTGTTATG
ATTCGTTGCTATTACGTGTTCACCGTGGCGTTGGTGCTGGCATTGTGATAAATCATGAGGTTTTTTTAGGTTATAAAAAT
AATGTCGCTGAAATTGGACATATTCAAGTTGATCCTCTCGGAAAACGTTGTTTATGTGGCAATGTGGGGTGTTTGGAAAC
TGTCGTGAGCAATACGGCGATTGAGCGCAAAATGCATGAGCTGTTAGAAGATGGCTACGAGAGTAAATGGTTATCGCTTG
AATCGCACGATATTGAAGCTATTTGTAAGGCAAGTAATAAACAGGATACGGCGGCGATTGAACTGATTGAACACGTTGGG
GTGCAAATTGGACGAGTGTTGGCGATGAGTGTGAATATGTTTAATCCCGAGAAGATCGTGATTTCTGGTGAAATTACACA
AGCTAAAAATATCTTGTTTTCGGCAATACAACGTTCTTTAGATAGCCATGCGTTGCCTGCTTTTGTCAAGAATACACCAT
TGGTTGCGTCAGAGCTGAAGAATGAAGATGTCATTGGGGCATTTGCGTTAATTAAACGTGCGTTATTAGATGGGAGTCTG
TTGCGTCGCTTGCTAGCAGACTAA

Upstream 100 bases:

>100_bases
CTTTAAAGTCCGACGTGGAGTAGCACAACAAATAAAAGTGATTTCTAATTCAGTCAATTCACTTTAGAATAATCAGGTTA
TTTTTTTATTGGGGTAAAAT

Downstream 100 bases:

>100_bases
AGTGCGGTTGCTTTTACAGCGATTTGTTCAAACTGTATGCGAACGCGTTAAAAATTTCATTTTTATAAAAAAAAGAGTTG
ACGAGTGGGGGCGATATCAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MRENHQIANVDLVKQMNSAVVYKLIDQQGPISRIQISELSQLAPASVTKITRHLLARGLIKEVEQQESTGGRRATSIVAE
HKAFRTILIRLGRQHATFAIMDLSTKLLKKAVVDLPEQQSVTSIEAFLLQHLTAFMAQHQKRGSEFIAVGITVPGFVDVK
TDMIQYMPHLDLDAPWDLANKISQHTQLATFIGHDVRSLALAEHYFGVTQDCYDSLLLRVHRGVGAGIVINHEVFLGYKN
NVAEIGHIQVDPLGKRCLCGNVGCLETVVSNTAIERKMHELLEDGYESKWLSLESHDIEAICKASNKQDTAAIELIEHVG
VQIGRVLAMSVNMFNPEKIVISGEITQAKNILFSAIQRSLDSHALPAFVKNTPLVASELKNEDVIGAFALIKRALLDGSL
LRRLLAD

Sequences:

>Translated_407_residues
MRENHQIANVDLVKQMNSAVVYKLIDQQGPISRIQISELSQLAPASVTKITRHLLARGLIKEVEQQESTGGRRATSIVAE
HKAFRTILIRLGRQHATFAIMDLSTKLLKKAVVDLPEQQSVTSIEAFLLQHLTAFMAQHQKRGSEFIAVGITVPGFVDVK
TDMIQYMPHLDLDAPWDLANKISQHTQLATFIGHDVRSLALAEHYFGVTQDCYDSLLLRVHRGVGAGIVINHEVFLGYKN
NVAEIGHIQVDPLGKRCLCGNVGCLETVVSNTAIERKMHELLEDGYESKWLSLESHDIEAICKASNKQDTAAIELIEHVG
VQIGRVLAMSVNMFNPEKIVISGEITQAKNILFSAIQRSLDSHALPAFVKNTPLVASELKNEDVIGAFALIKRALLDGSL
LRRLLAD
>Mature_407_residues
MRENHQIANVDLVKQMNSAVVYKLIDQQGPISRIQISELSQLAPASVTKITRHLLARGLIKEVEQQESTGGRRATSIVAE
HKAFRTILIRLGRQHATFAIMDLSTKLLKKAVVDLPEQQSVTSIEAFLLQHLTAFMAQHQKRGSEFIAVGITVPGFVDVK
TDMIQYMPHLDLDAPWDLANKISQHTQLATFIGHDVRSLALAEHYFGVTQDCYDSLLLRVHRGVGAGIVINHEVFLGYKN
NVAEIGHIQVDPLGKRCLCGNVGCLETVVSNTAIERKMHELLEDGYESKWLSLESHDIEAICKASNKQDTAAIELIEHVG
VQIGRVLAMSVNMFNPEKIVISGEITQAKNILFSAIQRSLDSHALPAFVKNTPLVASELKNEDVIGAFALIKRALLDGSL
LRRLLAD

Specific function: Acts as a repressor of the nagEBACD operon and acts both as an activator and a repressor for the transcription of the glmSU operon [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Escherichia coli, GI1786891, Length=402, Percent_Identity=54.4776119402985, Blast_Score=449, Evalue=1e-127,
Organism=Escherichia coli, GI1787878, Length=406, Percent_Identity=35.2216748768473, Blast_Score=273, Evalue=1e-74,
Organism=Escherichia coli, GI87082127, Length=339, Percent_Identity=22.4188790560472, Blast_Score=86, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR; PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 45036; Mature: 45036

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRENHQIANVDLVKQMNSAVVYKLIDQQGPISRIQISELSQLAPASVTKITRHLLARGLI
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHCCHHHHHHHHHHHHHHHH
KEVEQQESTGGRRATSIVAEHKAFRTILIRLGRQHATFAIMDLSTKLLKKAVVDLPEQQS
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHCCCCCCH
VTSIEAFLLQHLTAFMAQHQKRGSEFIAVGITVPGFVDVKTDMIQYMPHLDLDAPWDLAN
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCCCHHHHH
KISQHTQLATFIGHDVRSLALAEHYFGVTQDCYDSLLLRVHRGVGAGIVINHEVFLGYKN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEEEEEEEEECC
NVAEIGHIQVDPLGKRCLCGNVGCLETVVSNTAIERKMHELLEDGYESKWLSLESHDIEA
CCCCCCCEEECCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHH
ICKASNKQDTAAIELIEHVGVQIGRVLAMSVNMFNPEKIVISGEITQAKNILFSAIQRSL
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHH
DSHALPAFVKNTPLVASELKNEDVIGAFALIKRALLDGSLLRRLLAD
HCCCCHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHCHHHHHHHHCC
>Mature Secondary Structure
MRENHQIANVDLVKQMNSAVVYKLIDQQGPISRIQISELSQLAPASVTKITRHLLARGLI
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHCCHHHHHHHHHHHHHHHH
KEVEQQESTGGRRATSIVAEHKAFRTILIRLGRQHATFAIMDLSTKLLKKAVVDLPEQQS
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHCCCCCCH
VTSIEAFLLQHLTAFMAQHQKRGSEFIAVGITVPGFVDVKTDMIQYMPHLDLDAPWDLAN
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCCCHHHHH
KISQHTQLATFIGHDVRSLALAEHYFGVTQDCYDSLLLRVHRGVGAGIVINHEVFLGYKN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEEEEEEEEECC
NVAEIGHIQVDPLGKRCLCGNVGCLETVVSNTAIERKMHELLEDGYESKWLSLESHDIEA
CCCCCCCEEECCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHH
ICKASNKQDTAAIELIEHVGVQIGRVLAMSVNMFNPEKIVISGEITQAKNILFSAIQRSL
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHH
DSHALPAFVKNTPLVASELKNEDVIGAFALIKRALLDGSLLRRLLAD
HCCCCHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]