Click here to switch to the map view.

The map label for this gene is sbcB [H]

Identifier: 15602476

GI number: 15602476

Start: 712101

End: 713528

Strand: Direct

Name: sbcB [H]

Synonym: PM0611

Alternate gene names: 15602476

Gene position: 712101-713528 (Clockwise)

Preceding gene: 15602475

Following gene: 15602477

Centisome position: 31.54

GC content: 38.17

Gene sequence:

>1428_bases
ATGTCCACATCACCTGATTTTAGCTTTTTCATTTATGATTATGAGAGTTTTGGCGTTGACCCCGCTTCTGATCGTCCTGC
TCAATTCGCTGGTATTCGCACTGACATCAATTTCAATATCATCAGTGACCCTGTCATGTTTTATTGTAAACAAACCAATG
ATTATTTACCCGCGCCTGAAGCGGTTTTAGTCACAGGGATTACACCACAAGAATGTAATGAGAAGGGGATTCCTGAACCA
GAGTTTGCGGAACGTATTTTGCAAGAGTTCAGTCGTCCAAATACGTGTGTGATGGGATTTAATAATATTCGTTATGATGA
TGAAATGACACGCTATACCTTTTATCGCAATTTCATTGATCCCTATGAATATAGCTGGAAAAATGGCAATTCGCGTTGGG
ATTTATTGGATTTGGTTCGTGCTTGCTATGCTTTACGCCCAGAAGGTATTAATTGGGCTTATGATGAAGAAGGGATGCCG
TCATTTCGTTTAGAGAAATTGACTAAAGCCAATGGCATTGAACATAGCAATGCACATGATGCAATGGCGGATGTATATGC
CACCATTGCGATGGCAAAACTGATTAAAGAAAAACAACCCAAATTATTTCAATATTTCTTTGAAAATCGCGGTAAAAAAG
AAGTTGAGAAACTGATTGATACTGCAAATCTGACGCCATTGGTTCATGTTTCAGGTATGCTTGGTAATCATCGTGGTAAT
ACTACCTGGATTGTGCCTTTAGCCTGGCATCCGACCAATCAAAATGCTGTCATTTGTTGTGACTTAGCCGCAAATATAAC
AGATTTACTCAATAAAGATGCTAACGAATTACGTCAAAATCTTTATACTCCTAAAGCTGAATTAATTGAAAAGGGGATTT
TACCGGTACCATTAAAATTGGTGCACATTAATAAGTGTCCAATTCTTGCGCCTGCTAAAACCTTATTACCTGAAAATGCA
GCGCGGTTAGGTATTGATCGTACATTTTGTTTGGAAAACTTACAGCGCCTCAAATTATCACCACCTATTCGTGACAAGGT
CACTGAAATTTTCAATGAAGAACGGCATTTTGCCCCAAGCATCAATGTAGAAACAGAACTGTATAATGGGTTCTTTGATT
ACAATGATAAAAACAACATGGCGATTTTACGCCATTTACCAGAAGAAAAGCTGGCCGAGCATGGTTTAGCGTTTAAAGAT
ACGCGTATCCCCAAATTATTATTCCATTATCGGGCAAGACATTATTTTAATAGCTTAACTCGCGCAGAACAAATTCAATG
GCAAAAGTACCGTCATAAAAAGTTGGATCAAGTTGCACTGCAATTTGAGCAGAGCTTACAACGTTTAATCGCAGAGAATA
GTGAAAATCCGACTAATTTAGCCTTATTACAAAAAGTCTATGAGTATGGCGCAAAAATATTAGCCTAA

Upstream 100 bases:

>100_bases
CACAGTTTCGGATAACAACAGCCGCACAAAAGTGCGGTTTGTTTTTTCTGAATTTTATTGATTATGCTAGAATGACGTTT
ATTTGTTATTGAGTACGATT

Downstream 100 bases:

>100_bases
ATAGGTTGTCGAGCGTTAATTTTTGCTTAGCTTACTGCACAAATCATTTCAGATTTCACGTAGCGCGATCAATAAAAAAT
AAAGTCATGGAGAAGTTAAT

Product: exonuclease I

Products: NA

Alternate protein names: Exonuclease I; DNA deoxyribophosphodiesterase; dRPase [H]

Number of amino acids: Translated: 475; Mature: 474

Protein sequence:

>475_residues
MSTSPDFSFFIYDYESFGVDPASDRPAQFAGIRTDINFNIISDPVMFYCKQTNDYLPAPEAVLVTGITPQECNEKGIPEP
EFAERILQEFSRPNTCVMGFNNIRYDDEMTRYTFYRNFIDPYEYSWKNGNSRWDLLDLVRACYALRPEGINWAYDEEGMP
SFRLEKLTKANGIEHSNAHDAMADVYATIAMAKLIKEKQPKLFQYFFENRGKKEVEKLIDTANLTPLVHVSGMLGNHRGN
TTWIVPLAWHPTNQNAVICCDLAANITDLLNKDANELRQNLYTPKAELIEKGILPVPLKLVHINKCPILAPAKTLLPENA
ARLGIDRTFCLENLQRLKLSPPIRDKVTEIFNEERHFAPSINVETELYNGFFDYNDKNNMAILRHLPEEKLAEHGLAFKD
TRIPKLLFHYRARHYFNSLTRAEQIQWQKYRHKKLDQVALQFEQSLQRLIAENSENPTNLALLQKVYEYGAKILA

Sequences:

>Translated_475_residues
MSTSPDFSFFIYDYESFGVDPASDRPAQFAGIRTDINFNIISDPVMFYCKQTNDYLPAPEAVLVTGITPQECNEKGIPEP
EFAERILQEFSRPNTCVMGFNNIRYDDEMTRYTFYRNFIDPYEYSWKNGNSRWDLLDLVRACYALRPEGINWAYDEEGMP
SFRLEKLTKANGIEHSNAHDAMADVYATIAMAKLIKEKQPKLFQYFFENRGKKEVEKLIDTANLTPLVHVSGMLGNHRGN
TTWIVPLAWHPTNQNAVICCDLAANITDLLNKDANELRQNLYTPKAELIEKGILPVPLKLVHINKCPILAPAKTLLPENA
ARLGIDRTFCLENLQRLKLSPPIRDKVTEIFNEERHFAPSINVETELYNGFFDYNDKNNMAILRHLPEEKLAEHGLAFKD
TRIPKLLFHYRARHYFNSLTRAEQIQWQKYRHKKLDQVALQFEQSLQRLIAENSENPTNLALLQKVYEYGAKILA
>Mature_474_residues
STSPDFSFFIYDYESFGVDPASDRPAQFAGIRTDINFNIISDPVMFYCKQTNDYLPAPEAVLVTGITPQECNEKGIPEPE
FAERILQEFSRPNTCVMGFNNIRYDDEMTRYTFYRNFIDPYEYSWKNGNSRWDLLDLVRACYALRPEGINWAYDEEGMPS
FRLEKLTKANGIEHSNAHDAMADVYATIAMAKLIKEKQPKLFQYFFENRGKKEVEKLIDTANLTPLVHVSGMLGNHRGNT
TWIVPLAWHPTNQNAVICCDLAANITDLLNKDANELRQNLYTPKAELIEKGILPVPLKLVHINKCPILAPAKTLLPENAA
RLGIDRTFCLENLQRLKLSPPIRDKVTEIFNEERHFAPSINVETELYNGFFDYNDKNNMAILRHLPEEKLAEHGLAFKDT
RIPKLLFHYRARHYFNSLTRAEQIQWQKYRHKKLDQVALQFEQSLQRLIAENSENPTNLALLQKVYEYGAKILA

Specific function: Also functions as a DNA deoxyribophosphodiesterase that release deoxyribose-phosphate moieties following the cleavage DNA at an apurinic/apyrimidinic (AP) site by either an AP endonuclease AP lyase [H]

COG id: COG2925

COG function: function code L; Exonuclease I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788321, Length=468, Percent_Identity=55.1282051282051, Blast_Score=536, Evalue=1e-153,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013620
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T; PF08411 Exonuc_X-T_C [H]

EC number: =3.1.11.1 [H]

Molecular weight: Translated: 54900; Mature: 54769

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTSPDFSFFIYDYESFGVDPASDRPAQFAGIRTDINFNIISDPVMFYCKQTNDYLPAPE
CCCCCCCEEEEEEHHHCCCCCCCCCCCHHEEEEECCEEEEECCCCEEEEECCCCCCCCCC
AVLVTGITPQECNEKGIPEPEFAERILQEFSRPNTCVMGFNNIRYDDEMTRYTFYRNFID
EEEEECCCHHHCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHCCC
PYEYSWKNGNSRWDLLDLVRACYALRPEGINWAYDEEGMPSFRLEKLTKANGIEHSNAHD
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHH
AMADVYATIAMAKLIKEKQPKLFQYFFENRGKKEVEKLIDTANLTPLVHVSGMLGNHRGN
HHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEHHHHCCCCCC
TTWIVPLAWHPTNQNAVICCDLAANITDLLNKDANELRQNLYTPKAELIEKGILPVPLKL
EEEEEEEEECCCCCCEEEEEECHHHHHHHHCCCHHHHHHHHCCCHHHHHHCCCCCCCEEE
VHINKCPILAPAKTLLPENAARLGIDRTFCLENLQRLKLSPPIRDKVTEIFNEERHFAPS
EEECCCCCCCCHHHHCCCCHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCC
INVETELYNGFFDYNDKNNMAILRHLPEEKLAEHGLAFKDTRIPKLLFHYRARHYFNSLT
CCCCHHHHCCEECCCCCCCCHHHHHCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
RAEQIQWQKYRHKKLDQVALQFEQSLQRLIAENSENPTNLALLQKVYEYGAKILA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
STSPDFSFFIYDYESFGVDPASDRPAQFAGIRTDINFNIISDPVMFYCKQTNDYLPAPE
CCCCCCEEEEEEHHHCCCCCCCCCCCHHEEEEECCEEEEECCCCEEEEECCCCCCCCCC
AVLVTGITPQECNEKGIPEPEFAERILQEFSRPNTCVMGFNNIRYDDEMTRYTFYRNFID
EEEEECCCHHHCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHCCC
PYEYSWKNGNSRWDLLDLVRACYALRPEGINWAYDEEGMPSFRLEKLTKANGIEHSNAHD
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHH
AMADVYATIAMAKLIKEKQPKLFQYFFENRGKKEVEKLIDTANLTPLVHVSGMLGNHRGN
HHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEHHHHCCCCCC
TTWIVPLAWHPTNQNAVICCDLAANITDLLNKDANELRQNLYTPKAELIEKGILPVPLKL
EEEEEEEEECCCCCCEEEEEECHHHHHHHHCCCHHHHHHHHCCCHHHHHHCCCCCCCEEE
VHINKCPILAPAKTLLPENAARLGIDRTFCLENLQRLKLSPPIRDKVTEIFNEERHFAPS
EEECCCCCCCCHHHHCCCCHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCC
INVETELYNGFFDYNDKNNMAILRHLPEEKLAEHGLAFKDTRIPKLLFHYRARHYFNSLT
CCCCHHHHCCEECCCCCCCCHHHHHCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
RAEQIQWQKYRHKKLDQVALQFEQSLQRLIAENSENPTNLALLQKVYEYGAKILA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]