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The map label for this gene is trpD

Identifier: 15602446

GI number: 15602446

Start: 669582

End: 670583

Strand: Reverse

Name: trpD

Synonym: PM0581

Alternate gene names: 15602446

Gene position: 670583-669582 (Counterclockwise)

Preceding gene: 15602448

Following gene: 15602445

Centisome position: 29.7

GC content: 44.31

Gene sequence:

>1002_bases
ATGCAAACCGAGCAGTTACTTCACCAACTCTTTGAAAAAAAAGCGTTAAACCAACAACAAACCGAATTTCTTTTCACCGC
TATCGTACGTGGACAATTGGATAACTCACAACTCAGTGCCGCATTAATTGCCCTTAAACTGCGCGGTGAAACCCCTGAAG
AAATCAGTGGTGCCGTCACCGCATTACAAGCTGATGCCGAATCCTTTCCCATTCCAGACTACCCTTTTGCTGATATTGTC
GGCACGGGAGGAGATGGCGCCAATACCATTAATATTTCTACAGCTTCGGCAATTGTAGCGGCCAGTTATGGACTAAAAGT
CGCAAAACATGGTAATCGTAGTGTTTCGAGCCAAACGGGCGCCAGTGATCTGTTAACGGCCTTAGGGGTGAATGTCCATA
TATCAGCTCACAAAGCCAGACAAGCGTTGGATGAAATTGGCTTATGTTTTCTTTTTGCCCCACAATATCATCTGGGGTTT
CAACATGCGATTCCTGTCCGCCAAGCACTTAAAACACGCACTATTTTTAATATCTTAGGTCCCTTGATCAATCCAGCCAA
ACCCAAACGGCAGTTACTTGGTGTGTATTCATCTGACTTAATTCAACCTTATGCAGAAACGGTTGCCCGTTTGGGACATG
AGCATAGCGTAGTGGTACATGGCTCAGGCTTAGATGAAATTGCACTACATGGTGTGACCGAAGTCGCTGAAATCAAAGCA
GGACAAATCGAACGTTATACACTTACACCGCAAGATTTTGGCTTTCAGCCACAGCCACTTGAAACATTACGTGGCGGAAA
GCCTAGCGAAAATGCCCAAATTCTGACCGCACTTTTACAAGGCAAAGGTAAATTGGCACACCAACAAGCAGTGGCAATGA
ATAGTGCCATGTTGATGAGCTTATTTGGCTATCCAAACCTCAAACAAAATGCACAAGCGATTATGGATATTATCGCCACA
GGCAAACCATTTGAGACCTTACAACAACTTACCCAATATTAA

Upstream 100 bases:

>100_bases
TTTTTCTATTGGATGCAAAATTTACCCCTTGACATTATTATTCTGTACTAGTTTAATAGTTTTAAATTACAAAATAAAAA
TGGATTTAAAAGGAAAAAAC

Downstream 100 bases:

>100_bases
TTCGTTTTGATGACTTATTATTAAGAGAACCTAACAATGACACAAGCGTTTCCCTCTATTCTGCAAAAAATCATTCAAGA
TAAAACCACTTGGATTGCAG

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MQTEQLLHQLFEKKALNQQQTEFLFTAIVRGQLDNSQLSAALIALKLRGETPEEISGAVTALQADAESFPIPDYPFADIV
GTGGDGANTINISTASAIVAASYGLKVAKHGNRSVSSQTGASDLLTALGVNVHISAHKARQALDEIGLCFLFAPQYHLGF
QHAIPVRQALKTRTIFNILGPLINPAKPKRQLLGVYSSDLIQPYAETVARLGHEHSVVVHGSGLDEIALHGVTEVAEIKA
GQIERYTLTPQDFGFQPQPLETLRGGKPSENAQILTALLQGKGKLAHQQAVAMNSAMLMSLFGYPNLKQNAQAIMDIIAT
GKPFETLQQLTQY

Sequences:

>Translated_333_residues
MQTEQLLHQLFEKKALNQQQTEFLFTAIVRGQLDNSQLSAALIALKLRGETPEEISGAVTALQADAESFPIPDYPFADIV
GTGGDGANTINISTASAIVAASYGLKVAKHGNRSVSSQTGASDLLTALGVNVHISAHKARQALDEIGLCFLFAPQYHLGF
QHAIPVRQALKTRTIFNILGPLINPAKPKRQLLGVYSSDLIQPYAETVARLGHEHSVVVHGSGLDEIALHGVTEVAEIKA
GQIERYTLTPQDFGFQPQPLETLRGGKPSENAQILTALLQGKGKLAHQQAVAMNSAMLMSLFGYPNLKQNAQAIMDIIAT
GKPFETLQQLTQY
>Mature_333_residues
MQTEQLLHQLFEKKALNQQQTEFLFTAIVRGQLDNSQLSAALIALKLRGETPEEISGAVTALQADAESFPIPDYPFADIV
GTGGDGANTINISTASAIVAASYGLKVAKHGNRSVSSQTGASDLLTALGVNVHISAHKARQALDEIGLCFLFAPQYHLGF
QHAIPVRQALKTRTIFNILGPLINPAKPKRQLLGVYSSDLIQPYAETVARLGHEHSVVVHGSGLDEIALHGVTEVAEIKA
GQIERYTLTPQDFGFQPQPLETLRGGKPSENAQILTALLQGKGKLAHQQAVAMNSAMLMSLFGYPNLKQNAQAIMDIIAT
GKPFETLQQLTQY

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=325, Percent_Identity=57.8461538461538, Blast_Score=363, Evalue=1e-102,
Organism=Saccharomyces cerevisiae, GI6320561, Length=348, Percent_Identity=32.183908045977, Blast_Score=143, Evalue=5e-35,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_PASMU (P57856)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_245518.1
- ProteinModelPortal:   P57856
- SMR:   P57856
- GeneID:   1243928
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM0581
- NMPDR:   fig|272843.1.peg.581
- HOGENOM:   HBG559996
- OMA:   LGVYSPE
- ProtClustDB:   PRK00188
- BioCyc:   PMUL272843:PM0581-MONOMER
- BRENDA:   2.4.2.18
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 35880; Mature: 35880

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTEQLLHQLFEKKALNQQQTEFLFTAIVRGQLDNSQLSAALIALKLRGETPEEISGAVT
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHEEEECCCCHHHHHHHHH
ALQADAESFPIPDYPFADIVGTGGDGANTINISTASAIVAASYGLKVAKHGNRSVSSQTG
HHHCCCCCCCCCCCCHHHHEECCCCCCCEEEEEHHHHHHHHHHCCCEECCCCCCCCCCCC
ASDLLTALGVNVHISAHKARQALDEIGLCFLFAPQYHLGFQHAIPVRQALKTRTIFNILG
HHHHHHHHCCEEEEEHHHHHHHHHHCCEEEEECCCHHCCCHHHHHHHHHHHHHHHHHHHH
PLINPAKPKRQLLGVYSSDLIQPYAETVARLGHEHSVVVHGSGLDEIALHGVTEVAEIKA
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHCHHHHHHHCC
GQIERYTLTPQDFGFQPQPLETLRGGKPSENAQILTALLQGKGKLAHQQAVAMNSAMLMS
CCEEEEEECCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
LFGYPNLKQNAQAIMDIIATGKPFETLQQLTQY
HHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCC
>Mature Secondary Structure
MQTEQLLHQLFEKKALNQQQTEFLFTAIVRGQLDNSQLSAALIALKLRGETPEEISGAVT
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHEEEECCCCHHHHHHHHH
ALQADAESFPIPDYPFADIVGTGGDGANTINISTASAIVAASYGLKVAKHGNRSVSSQTG
HHHCCCCCCCCCCCCHHHHEECCCCCCCEEEEEHHHHHHHHHHCCCEECCCCCCCCCCCC
ASDLLTALGVNVHISAHKARQALDEIGLCFLFAPQYHLGFQHAIPVRQALKTRTIFNILG
HHHHHHHHCCEEEEEHHHHHHHHHHCCEEEEECCCHHCCCHHHHHHHHHHHHHHHHHHHH
PLINPAKPKRQLLGVYSSDLIQPYAETVARLGHEHSVVVHGSGLDEIALHGVTEVAEIKA
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHCHHHHHHHCC
GQIERYTLTPQDFGFQPQPLETLRGGKPSENAQILTALLQGKGKLAHQQAVAMNSAMLMS
CCEEEEEECCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
LFGYPNLKQNAQAIMDIIATGKPFETLQQLTQY
HHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100